Mwana wenyu ane kenza iyi isingawanzoitiki here? Ngatikurukurei nezveRhabdoid Tumor!

Vanaamai nababa, mutoro mukuru pamoyo yenyu uye chimwe chinhu chamusingatombodi kufunga nezvacho kana mwana wenyu aziva kuti ane kenza. Asi dzimwe nguva, vana vanogona kurwara zvatisingatarisiri. Nhasi tichataura nezverudzi rwekenza rusingawanzoitiki, runopararira nekukurumidza runobata vana, kunyanya vana vadiki. Iyi inonzi Rhabdoid Tumor . Unganzwa zvisinganzwisisike kana ukanzwa zita iri, asi ngatitsanangurei zviri nyore.

Chii chinonzi Rhabdoid Bumor? Zvichitaurwa zviri nyore...

Rhabdoid Bundu regomarara igomarara risingawanzoonekwi uye rinokura nekukurumidza . Rinonyanya kuwanikwa muvana vadiki nevacheche . Kana richitariswa nemaikorosikopu, masero egomarara aya akafanana nerhabdomyoblasts , rudzi rwesero rinoumba tsandanyama. Ndosaka richinzi "rhabdoid." Gomarara iri rinogona kukura muitsvo dzemwana, nyama dzakapfava, kana mutsinga dzeuropi nemusana. Zvinosuwisa kuti gomarara iri rinogona kupararira nekukurumidza, zvichiita kuti zviome kurapa.

Kune mhando dzakasiyana dzeRhabdoid Tumor here?

Ehe, kune mhando dzakawanda dzegomarara iri zvichienderana nekuti rinoitika kupi. Ngationei kuti ndedzipi.

1. Bundu reRhabdoid reKidney (RTK)

Iri ibundu reRhabdoid reitsvo mumwana. Dzimwe nguva rinopfupikiswa sekuti ``(RTK)``.

2. Matumbu eRhabdoid Anouraya Ari Kunze Kwemusoro kana Kunze Kwetsvina

Rudzi urwu rwegomarara runogona kukura munyama dzakapfava dzemwana nedzimwe nhengo dzemuviri, dzakadai sechiropa, mapapu, neganda. Runonziwo malignant rhabdoid tumors (MRT) . "Malignant" zvinoreva gomarara.

3. Matumbu erudzi rweAtypical Teratoid Rhabdoid (ATRT)

Rudzi urwu rwegomarara rerhabdoid runokura mutsinga dzemukati memwana, muuropi nemumusana. Murudzi urwu rwegomarara, masero egomarara anotanga kuumbwa muuropi hwemwana kana mumutsipa. Inenge 50% yegomarara iri (ATRT) rinokura mucerebellum (inodzora kufamba uye kuenzana) kana muuropi ( inodzora zvinhu zvakaita sekufema uye kurova kwemoyo).

Ndiani ane mukana mukuru wekuva neRhabdoid Tumors?

Inonyanya kubata vacheche nevana vadiki , kunyanya avo vari pakati pemwedzi 11 ne18 . Vakuru vane mikana mishoma yekubata chirwere ichi.

Izvi hazviwanzoitiki, dzimwe ongororo dzinoti zvinoitika muvanhu vasingasviki mumwe chete pavanhu miriyoni imwe chete.Gomarara iri rinonzi rinoitika zvishoma. Izvi zvinoreva kuti chirwere chisingawanzoitiki.

Sei bundu iri reRhabdoid richikura? Chii chinokonzera izvi?

Kazhinji, chikonzero chikuru chegomarara rerhabdoid ikuchinja kwemajini mujini reSMARCB1 . Fungidzira kuti pane kakudzivirira mumuviri wedu kanodzora kukura kwemasero. Iri jini reSMARCB1 ijini rinodzivirira bundu . Rinoburitsa puroteni inodzora kukura kwemasero. Kufanana nemapurisa, rinomisa masero kuti asapatsanuke nekukurumidza. Saka, kana paine chikanganiso, ndiko kuti, kuchinja, mujini iri reSMARCB1, kutonga ikoko kunorasika uye masero anopatsanuka nekukurumidza, zvichikonzera gomarara . Kashoma, magomarara aya anogonawo kukura nekuda kwekuchinja mune rimwe jini rinodzivirira bundu rinonzi SMARCA4. Kunyangwe vamwe vana vachigona kugara nhaka jini iri rakachinja kubva kuvabereki vavo, kazhinji magomarara aya anoitika nekuda kwekuchinja kwemajini kutsva kunoitika pasina nhoroondo yemhuri . Izvi zvinoreva kuti kunyangwe pasina munhu mumhuri akambova nekuchinja uku, masero emwana anogona kunge aine kuchinja uku netsaona. Pakurapa mwana, kuongororwa kwemajini kunogona kuitwa kuti paonekwe shanduko yemajini iyi.

Ndezvipi zviratidzo zveRhabdoid Tumor?

Zviratidzo zvinogona kusiyana zvichienderana nezera remwana uye nzvimbo yekenza . Zviratidzo zvinowanzo tanga munzvimbo iri kukura kenza. Izvi zvinogona kusanganisira kukuvara kwetsinga, kunetseka kufema, kana bundu mudumbu remwana. Nekuti kenza iyi inopararira nekukurumidza, zviratidzo zvinogona kuoneka nekukurumidza. Zvimwe zviratidzo zvinogona kusanganisira:

• Kugara uchidziya muviri.
• Musoro .
• Ropa muweti ( Hematuria ) .
• Kusvotwa nekurutsa .
• Manodhi elymph akazvimba .
• Kugara akatsamwa, asina kugadzikana (Kutsamwa).
• Chikafu hachina kunaka .
• Kurara kusingawanzoitiki.
• Muvana vacheche, saizi yemusoro inokura.
• Kutadza kugadzikana kana kuoma kufamba.

Kana mwana wako aine chimwe chezviratidzo izvi kana kupfuura, zvakakosha kuti utsvage rubatsiro rwechiremba nekukasika.

Sei?Gomarara iri reRhabdoid rinoonekwa sei?

Chiremba anoongorora mwana wenyu achatanga aita bvunzo yemuviri wenyu uye achakubvunzai nezvezviratidzo zvemwana wenyu. Vachabva varaira bvunzo dzinoverengeka kuti vasimbise chirwere ichi. Izvi zvinogona kusanganisira:

• Ultrasound scan: Izvi zvinoshandisa mafungu eruzha ane simba guru kugadzira mufananidzo (sonogram) wenhengo dzemukati dzemwana.
• CT scan: Izvi zvinoshandisa X-rays nekombiyuta kugadzira mufananidzo wezvikamu zvitatu (3D) wenyama nemapfupa emwana akapfava.
• MRI scan: Izvi zvinoshandisa magineti, mafungu eredhiyo, nekombiyuta kugadzira mifananidzo yakadzama yenzvimbo dzakadai seuropi hwemwana nemusana.
• Kuongororwa kwetsinga: Izvi zvinoedza uropi hwemwana, musana, uye mashandiro etsinga.
• Kuboorwa kwemusana/Kupomba kwemusana: Muizvi, sampuro ye cerebrospinal fluid (CSF) inotorwa kubva kumusana wemwana yoongororwa nemaikorosikopu kuti ione kana paine masero ekenza.

Zvisinei, ma scan aya anogona kuratidza bundu re rhabdoid rinotaridzika semamwe marudzi ekenza. Nokudaro, vanachiremba vanowanzo tora masampuli enyama uye vanoraira mimwe miedzo. Miedzo iyi inosanganisira:

• Kuongororwa kwemajini: Muenzaniso weropa remwana kana nyama yake unotorwa woongororwa kuti uone kana paine shanduko mumajini `SMARCB1` uye `SMARCA4`.
• Kuongororwa kwemuviri: Mukuita uku, chiremba anoshandisa tsono kutora sampuli diki yebundu. Nyanzvi yezvirwere inozoritarisa pasi pemaikorosikopu kuti ione kana paine masero ekenza. Kana masero ekenza akawanikwa, bundu rakawanda rinogona kubviswa panguva yekuvhiyiwa kana pakuvhiyiwa kunotevera.
• Immunohistochemistry: Iyi bvunzo chaiyo. Inoshandisa ma antibodies kutsvaga mamwe ma markers/antigens mumuenzaniso wenyama yemwana wako. Ma markers aya anogona kubatsira kuona kana iri kenza ye rhabdoid kana imwe mhando yekenza.

Gomarara reRhabdoid rinorapwa sei?

Chiremba wezvirwere zvegomarara revana ndiye anotungamira mukurapa mwana. Anoshanda nechikwata chevamwe nyanzvi kugadzira hurongwa hwekurapa hunonyatsokodzera mwana. Mishonga yakasiyana-siyana inogona kushandiswa pamwe chete kurapa gomarara rerhabdoid. Nekuti gomarara iri rinopararira nekukurumidza, zvidzidzo zvakaratidza kuti kushandisa mishonga yakawanda pamwe chete kunogona kuuraya masero egomarara pane kushandisa rimwe chete.

• Kuvhiyiwa: Kana biopsy ikasabvisa kenza, danho rekutanga, kana zvichibvira, nderekuvhiya kubvisa kenza yakawanda sezvinobvira, pamwe yese.
• Kurapa nemakemikari (Chemotherapy): Izvi zvinosanganisira kupa mishonga inomisa kukura kwemasero ekenza. Mishonga iyi inouraya mamwe masero ekenza uye inodzivisa mamwe kupatsanuka. Zvisinei, mishonga iyi haigone kusiyanisa masero akanaka nemasero ekenza, saka inogona kukonzera migumisiro yakaipa.
• Kurapa kenza yemudumbu nemasero emuviri: Kurapa kenza yemudumbu nemasero emuviri nemasero emuviri nemasero emuviri nemasero emudumbu kunogona kuuraya masero akawanda ekenza. Zvisinei, inourayawo masero ane hutano, akadai semasero anogadzira ropa mumongo wemapfupa. Kuti izvi zviitike, mamwe mamongo emapfupa emwana anotorwa uye anochengetwa asati apiwa chemotherapy yakawanda. Mushure mekurapwa, mapfupa anodzoserwa kumwana kuti atsive masero akaparadzwa.
• Kurapa nemwaranzi: Izvi zvinoshandisa X-rays ine simba guru kuderedza kana kuparadza masero egomarara. Zvisinei, nekuti kurapwa nemwaranzi kunogona kukanganisa kukura kwemwana nekukura kwehuropi, chiyero chinogadziriswa zvichienderana nezera nehukuru hwemwana.
• Miedzo yekiriniki: Chiremba anogonawo kukurudzira miedzo mitsva yekiriniki (mhando itsva dzechemotherapy, kurapwa kwakanangana, kana mishonga yekudzivirira muviri) yekurapa kenza yemwana wako.

Ndezvipi zvingakonzera migumisiro yekurapwa?

Kurapa kenza, kunyanya chemotherapy, kunogona kukonzera migumisiro yakaipa. Izvi zvinodaro nekuti mishonga inoshandiswa kuuraya masero ekenza inourayawo masero ane hutano. Zvisinei, migumisiro yakawanda inonyangarika mushure mekunge kurapwa kwamiswa . Unogona kushanda nechikwata chevanachiremba vemwana wako kugadzirisa migumisiro yakaipa iyi. Migumisiro inowanzo sanganisira:

• Kurasikirwa nebvudzi `(Alopecia)` .
• Chikafu hachina kunaka.
• Kuzvimba.
• Manyoka.
• Kusvotwa nekurutsa.
• Maronda pahuro nemumuromo.
• Kuzvimba `(Edema)` .
• Kushaya hope.
• Kuneta zvakanyanya.
• Matambudziko ekurangarira.

Matumbu eRhabdoid anogona kudzivirirwa here?

Zvinosuwisa kuti magomarara aya anokonzerwa nekuchinja kwemajini, saka hapana nzira yekudzivirira . Zvisinei, kana mumwe munhu mumhuri yako akambova negomarara rerhabdoid kana mamwe magomarara, uye uri kutarisira mwana, zvakanaka kutaura nachiremba wako nezvemajini . Kupa mazano emajini kunogona kukubatsira kunzwisisa njodzi yako yekuva nechirwere chemajini mumwana wako.

Gomarara reRhabdoid rinogona kurapwa here? Remangwana remwana richava rakaita sei?

Chiremba ari kurapa mwana wenyu anogona kukupai mhinduro chaiyo kumubvunzo uyu. Zvisinei,Zvinosuwisa kuti vana vazhinji vane chirwere chegomarara remarara havararame kwemakore anopfuura mashoma. Zvisinei, kana mwana akaonekwa aine chirwere ichi mushure memakore maviri , fungidziro yacho inogona kunge iri nani zvishoma. Mwero wekurarama kwegomarara iri unoenderana nezvinhu zvakati wandei:

• Zera remwana.
• Kana kenza iri mumuviri wemwana.
• Kana kenza yapararira kune dzimwe nhengo dzemuviri.
• Kubviswa kwegomarara rakawanda sei nekuvhiyiwa.
• Kuti mwana achaita sei kana achirapwa kenza.

Nekuti kansa yerudzi rwemalignant rhabdoid haiwanzoitiki, nhamba dzenguva yekurarama dzinobva pahuwandu hushoma hwevarwere. Nokudaro, tarisiro chaiyo yehupenyu hwemwana inogona kusiyana. Zvidzidzo zvinoratidza kuti mwero wekurarama kwemakore mashanu wekansa yerudzi rwe rhabdoid yeitsvo (RTK) uri pakati pe20% ne25% . Izvi zvinoreva kuti pakati pe20% ne25% yevanhu vanoonekwa vaine RTK vachiri vapenyu makore mashanu mushure mekuonekwa. Mwero wekurarama kwemakore mashanu wekansa yerudzi rwe atypical teratoid rhabdoid (ATRT) uri pakati pe32% ne50%.

Zvakajairika kunzwa mutoro mukuru uye kusuruvara paunonzwa chimwe chinhu chakadai. Asi yeuka, hausi wega.

Chii chandinofanira kubvunza chiremba?

Zvakajairika kuva nemibvunzo yakawanda kana ukaona kuti mwana wako ane kenza. Heano mimwe mibvunzo yekurangarira kubvunza panguva iyoyo:

• Mwana wangu ane kenza yerudzii?
• Ko kenza yemwana wangu iri padanho ripi?
• Ndezvipi bvunzo dzinofanira kuitwa nemwana wangu?
• Ndezvipi zvingasarudzwa zvekurapa kenza yemwana wangu?
• Mikana ipi yekuti kurapwa uku kubudirire?
• Ndezvipi zvidzidzo zvekiriniki zviripo kuti mwana wangu atore chikamu mazviri?
• Tingaziva sei kana kurapwa kwacho kwabudirira?

Kutevera kunoitiswa sei panguva yekurapwa uye mushure mekurapwa?

Mukurapa kwegomarara kwemwana wenyu, mimwe yemiedzo inoshandiswa kuona chirwere ichi inofanira kudzokororwa. Miedzo iyi inoshandiswa kuyera kuti kurapwa kuri kushanda zvakanaka sei. Zvichibva pamigumisiro yemiedzo iyi, timu yenyu yezvekurapa ichashanda nemi kuti isarudze matanho anotevera amunofanira kutora. Izvi zvinogona kusanganisira kuramba muchichinja, kuchinja, kana kumisa kurapwa. Mushure mekunge mwana wenyu apedza kurapwa gomarara, achafanira kudzoka kuzoongororwa nguva nenguva uye kuongororwa . Munguva yekutevera uku, chiremba wenyu achaongorora kana mamiriro emwana wenyu avandudzika kana kuti chirwere chacho chadzoka. Kutevera uku kunogona kugara kwemakore akati wandei mushure mekurapwa.

Pakupedzisira, yeukai... (Mharidzo Yekuenda Nayo Kumba)

Tinoziva kuti zvinorwadza kunzwa nhau dzekuti mwana wako ane kenza. Asi zvakakosha kuyeuka kuti hausi wega.Chikwata chose chiri kurapa mwana wenyu, kusanganisira vanachiremba nevanamukoti, chiripo kuti chikubatsirei imi nemhuri yenyu munguva ino yakaoma. Kune mishonga yekurapa bundu reRhabdoid, uye pane tariro kumwana wenyu . Taurai nachiremba wemwana wenyu nezvekujoinha boka rekutsigira kenza kuvabereki kana mhuri. Munogona kuwana nyaradzo huru nekukurudzirana nekugovana nyaya yenyu uye kunzwa nezvezviitiko zvevamwe vanhu.