Wakambonyorerwa mushonga we "Sulfa" nachiremba here muhupenyu hwako? Pamwe unoyeuka, kana kuti pamwe wakambonzwa nezvawo. Vanhu vazhinji pavanonzwa izwi rekuti "sulfa," vanofunga kuti mushonga mumwe chete. Asi chaizvoizvo izita rinowanzo shandiswa pakurapa boka guru remishonga. Saka nhasi, ngatitaurei nezvema "sulfonamides" aya, zvaanoita, uye zvinhu zvakakosha zvaunofanira kuziva nezvazvo.
Chii chaizvo chinonzi sulfonamides idzi?
Zvichitaurwa zviri nyore, sulfonamides iboka remishonga inogadzirwa murabhoritari nevanhu (synthetic). Haisi yemuzvarirwo. Kana ukatarisa chimiro chemakemikari chemishonga iyi, yese ine chikamu chakafanana chine chinhu chinonzi sarufa. Apa ndipo panobva zita rekuti "sulfonamide".
Saka mishonga iyi inoshanda sei? Funga nezvazvo, mabhakitiriya anopinda mumiviri yedu anoda chikafu kuti ararame uye apararire. Chimwe chezvinovaka muviri zvinodiwa nemabhakitiriya aya ifolate, kana kuti vhitamini B9 . Zvinoitwa nemishonga iyi yesulfa kuvharira kugona kwemabhakitiriya kugadzira folate iyi. Zvakafanana nekushaya chikafu nenzara. Kana mabhakitiriya akarasikirwa nefolate, haagone kupatsanurana kana kukura uye kufa zvishoma nezvishoma.
Zvino ungave uchifunga kuti, "Isu tinodawo folate, saka hazvizotikuvadzi here?" Mubvunzo wakanaka uyu! Asi isu, kureva vanhu, tinowana folate yatinoda kubva muchikafu chatinodya. Hatigadzire folate mumiviri yedu. Saka mishonga iyi haikanganisi masero edu zvakananga nenzira iyoyo. Ndosaka iri nzira inoshanda zvikuru yekuuraya mabhakitiriya.
Mishonga yesulfa inokosha nhasi sezvayaikosha kare ikako.
Mishonga yeSulfonamides yakanga isiri yekutanga kuwanikwa kwemishonga inorwisa mabhakitiriya. Asi mushure mekuwanikwa kwayo muma1930, ndiyo yaive mhando yepamusoro uye ine simba yemishonga inorwisa mabhakitiriya yaiwanikwa kwemakore angangoita gumi. Penicillin isati yazivikanwa, mishonga iyi yesulfa yakabatsira zvikuru kuderedza kufa kunokonzerwa nehutachiona hwemabhakitiriya.
Asi nhasi uno, sulfonamides haingoshandiswi kurapa hutachiona hwemabhakitiriya chete. Rudzi urwu rwemishonga runoshandiswa kurapa zvirwere zvakasiyana-siyana, zvinosanganisira chirwere cheshuga, BP, utachiona hweHIV, nedzimwe mhando dzekenza.
Ndeipi mimwe mishonga iri muboka resulfonamide?
Rondedzero iyi yakareba zvishoma, asi ichakupa pfungwa yekuti mishonga iyi inoshandiswa kangani. Ngatiiparadzanisei muzvikamu zviviri.
| Zita reMushonga | Mashandisirwo Akajairika |
|---|---|
| 1. Mishonga inorwisa mabhakitiriya inonzi sulfonamides | |
| Sulfacetamide | Semushonga wekubvisa mapundu kana semushonga wemaziso wezvirwere zvemaziso (conjunctivitis) |
| Sulfadiazine (Silvadene®) | Kudzivirira hutachiona hwemaronda ekutsva |
| Sulfasalazine (Azulfidine®) | Ulcerative colitis uye rheumatoid arthritis |
| Sulfamethoxazole (iri muBactrim™) | Mabhakitiriya akasiyana-siyana akadai sehutachiona hwemunzira yemudumbu, hutachiona hwekufema |
| 2. Mishonga isingashandisi mishonga inorwisa mabhakitiriya inonzi sulfonamides | |
| Furosemide (Lasix®), Bumetanide (Bumex®) | Mishonga inobvisa mvura mumuviri (diuretics) inoderedza kuzvimba kwemuviri uye BP yakakwira |
| Celecoxib (Celebrex®) | Kune marwadzo emapfundo akadai searthritis |
| Sumatriptan (Imitrex®) | Kune misoro ine migraine |
| Tolbutamide, Chlorpropamide | Kune chirwere cheshuga cherudzi rwechipiri |
| Tamsulosin (Flomax®) | Kune matambudziko eweti anokonzerwa nekukura kweprostate gland (benign prostatic hyperplasia) |
| Darunavir (Prezista®) | Mushonga wekudzivirira hutachiona hweHIV |
Kubva pane izvi, unogona kuona kuti kunyangwe "sulfa" ichinzi "sulfa", haisi chinhu chimwe chete, uye kuti imhando yakakura yemishonga.
Nyaya ye 'sulfa allergy' ndeyechokwadi here?
Ehe, allergies kumishonga yesulfonamide inogona kuitika. Pasi rose, vanhu vari pakati pe3 ne8 pavanhu zana vane allergies kumishonga yesulfa. Asi izvi zvakafanana nehuwandu hweallergies kune mamwe maantibiotic akajairika, akadai sepenicillin.
Asi chinhu chakakosha pano ndechekuti nekuti wakamborwara nemushonga mumwe chete wesulfa, hauzove neallergy kune mimwe mishonga yese yesulfa . Semuenzaniso, munhu ane allergy kumushonga weBactrim anogona kunge asina allergy kumushonga wekurwadziwa weCelebrex. Nekuti maumbirwo emakemikoro emishonga miviri akasiyana.
Saka, kana wakambova nechirwere chekusawirirana nemishonga yesulfa, iva nechokwadi chekuudza chiremba wako kuitira kuti akupe imwe nzira yakachengeteka.
Pane migumisiro kana njodzi dziripo pamushonga uyu here?
Kufanana nemushonga upi zvawo, sulfonamides inogona kuva nezvayakaipira uye njodzi.
- Kusabatwa neMabhakitiriya: Nekufamba kwenguva, mamwe mabhakitiriya anogona 'kupindwa muropa' nemishonga iyi uye otanga kusabatwa nayo. Mushonga wacho unobva warega kushanda pabhakitiriya iyoyo.
- Migumisiro yakaipa: Kashoma, vamwe vanhu vanogona kusangana nezvirwere zvakakomba zveganda. Stevens-Johnson syndrome uye toxic epidermal necrolysis zvinhu zviviri zvakakomba, asi zvisingawanzoitiki. Usati watya nezvechinhu chakadai, zvakanaka kutaura nachiremba wako nezvemushonga wauri kutora.
Bactrim isulfonamide here?
Ehe, muchikamu. Mushonga weBactrim™ une sulfamethoxazole, sulfonamide, nemumwe mushonga unonzi trimethoprim, unoshanda zvakafanana.
Ko Celebrex mushonga wesulfa zvakare here?
Ehe. Celecoxib (Celebrex®) mushonga wekurwadziwa kwemusoro uri muboka resulfonamide.
Mushonga uyu unogona kukonzera makristaro muweti here?
Mimwe mishonga yesulfa inogona kukonzera kuti weti iumbwe nemakristaro. Izvi hazviwanzoitika. Kana chiremba wako akakunyorera mushonga, achakuudza zvekuita kudzivirira izvi (semuenzaniso, inwa mvura yakawanda). Saka usazvidya mwoyo nazvo.
Mishonga yeSulfonamides yakaedzwa zvakanaka uye yakasimbiswa ine nhoroondo yemakore anopfuura 90. Pakutanga yaishandiswa chete pakutapukirwa nemabhakitiriya, asi ikozvino inoshandiswa kurapa zvirwere zvakasiyana-siyana kubva kumusoro kusvika kutsoka.
Mharidzo Yekuenda Nayo Kumba
- Sulfonamides, kana kuti "sulfa," haisi mushonga mumwe chete. Iboka guru remishonga inoshandiswa kurapa zvirwere zvakasiyana-siyana, zvinosanganisira chirwere cheshuga, BP, hutachiona, uye marwadzo.
- Kana wakambova nechirwere chekusawirirana nemishonga yesulfa, iva nechokwadi chekuzivisa chiremba wako usati watora chero mushonga.
- Mushonga wega wega wesulfa wakasiyana. Nekuti une allergy kune mumwe, usazvidya moyo kuti uchava neallergy kune mimwe yese. Bvunza chiremba wako nezvazvo.
- Inwa mushonga chero upi zvawo kana wapiwa zano nachiremba chete. Kana uine zvinokunetsa kana kutya nezvemigumisiro yemishonga, taura nachiremba wako nezvazvo pachena.
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