Chii chinonzi Wernicke-Korsakoff Syndrome? Ngatikurukurei nezvazvo!

Wakambonzwa nezvechirwere chinoshamisa chinokanganisa uropi nendangariro here? Dzimwe nguva, hatitombozivi kuti kana muviri wedu usina mavhitamini, kunyanya vhitamini B1 inonzi ``Thiamine``, uropi hwedu hunogona kukuvara zvakanyanya. Chimwe chezvirwere zvakakomba zvakadaro i``Wernicke -Korsakoff Syndrome`` (``WKS``) . Ichi chirwere chinoda kurapwa nekukurumidza. Tinofanira kutaura nezvazvo zviri nyore, nenzira yatinonzwisisa here?

Chii chinonzi Wernicke-Korsakoff syndrome (`WKS`) chaizvo?

Zvichitaurwa zviri nyore, ichi chirwere chinokanganisa uropi hwedu nendangariro. Chikonzero chikuru cheizvi ndechekuti miviri yedu ine kudzikira kukuru kwe'Thiamine' ('Thiamine') kana vhitamini B1 . Funga nezvazvo, muviri wedu wakaita semota. Injini yemota iyi uropi. Injini inoda peturu kuti ishande. Saizvozvowo, vhitamini inonzi 'Thiamine' ('Thiamine') inokosha kuti uropi hwedu netsinga dzedu zvishande. Vhitamini iyi ndiyo inoshandura chikafu chatinodya kuita simba. Saka kana 'Thiamine' iyi ('Thiamine') yadzikira, uropi hahuwani simba rahunoda, uye masero europi anotanga kukuvara.

Kune matanho maviri makuru mu 'WKS' iyi:

1. Wernicke encephalopathy: Uku ndiko kukuvara kwekutanga, kwakakomba, uye kamwe kamwe kweuropi. Kunoda kurapwa nekukasika.

2. Korsakoff syndrome: Ichi chirwere chinokanganisa ndangariro zvakanyanya.

Inotumidzwa zita iri kubva kuna Carl Wernicke, chiremba wepfungwa wekuGermany uye Sergei Korsakoff, chiremba wepfungwa wekuRussia, avo vakatanga kuona chirwere ichi.

Chii chiri hukama huripo pakati pe'Wernicke's encephalopathy' ne'Korsakoff syndrome'?

Zviviri izvi zvine hukama. Kutaura chokwadi, chirwere chinonzi ``Wernicke encephalopathy``, kana chikarapwa nenguva, ndicho chinokura zvishoma nezvishoma kuita dambudziko guru rekuyeuka rinonzi ``Korsakoff syndrome``.

Kazhinji pane zviratidzo zvikuru zvitatu zveWernicke encephalopathy:

• Kuvhiringidzika: Kurasikirwa nepfungwa, kurasikirwa nenzvimbo nenguva.
• Kurasikirwa nekuenzana uye kutadza kudzora mafambiro (`Ataxia`): Kufamba kunova kusina kugadzikana uye makumbo anova akaoma kudzora.
• Kuchinja kwekuona uye matambudziko emaziso: Kufamba kwemaziso kusina kujairika, sekunge kuona kaviri.

Pamusoro peizvi, dzimwe nguva kunyange tsandanyama dzinogona kushaya simba.

Kana zviratidzo izvi zvikaramba zviripo kwenguva yakareba, kukuvara kunogara kwenguva refu kunoitika kuuropi nemasero etsinga. Apa ndipo panoitika kurasikirwa kukuru kwendangariro uye ndangariro itsva dzisingachayeukwe. Izvi zvinonzi ``Korsakoff syndrome``.

Wernicke-Korsakoff Syndrome (WKS) chirwere chinogona kuramba chichiipa nekufamba kwenguva uye chinogona kutokonzera njodzi kuhupenyu. Saka, kurapwa nekukurumidza nethiamine kwakakosha. Kuita izvi kunogona kubatsira kuderedza zviratidzo uye kudzivirira kukuvara kusingaperi kwendangariro nemamwe mabasa europi.

Kana iwe kana mumwe munhu ari pedyo newe aine zviratidzo izvi, unofanira kuona chiremba nekukasika kana kuenda kuchipatara chiri pedyo newe.

Ndiani anonyanya kukanganiswa nemamiriro ezvinhu aya?

Chirwere cheWernicke-Korsakoff (WKS) chinowanzoitika muvarume kupfuura vakadzi. Chinowanzoonekwa muvanhu vane makore ari pakati pe30 ne70. Vanhu vazhinji vanowana chirwere ichi nekuda kwekushandisa doro varume vane makore anopfuura makumi mana. Zvisinei, vakadzi nevechidiki vanogonawo kuwana chirwere ichi nekuda kwezvikonzero zvisiri doro. Hazviwanzoonekwa muvana vadiki.

Ndiani ari panjodzi huru yekubatwa nechirwere cheWernicke-Korsakoff?

Wernicke encephalopathy chirwere chinowanzoonekwa muvanhu vanoshandisa doro zvakanyanya (doro rinoshandiswa zvisina kunaka). Kana doro rikanwiwa kwenguva yakareba, rinokuvadza dumbu nedumbu. Rinokanganisawo kugona kwemuviri kunwa mavhitamini (malabsorption). Zvinonzi vanhu vanosvika 80% vanonwa doro havagone kunwa kana kuchengetedza thiamine yakakwana.

Pamusoro pezvo, vanhu vasingakwanise kunwisa chikafu zvakanaka nekuda kwemamwe mamiriro ehutano vanogonawo kuva ne "WKS". Semuenzaniso, zvinogona kuitika mushure mekuvhiyiwa kwekudzikisa uremu ('bariatric surgery') kana semhedzisiro ye 'chemotherapy' yekenza.

Heano zvimwe zvinhu zvinokonzera njodzi:

• Zvirwere zvemudumbu, semuenzaniso, chirwere chemudumbu chinozvimba kana gastropathy.
• Kenza (kunyanya muzviitiko zvakakomba).
• Mahormone ethyroid akawandisa (thyrotoxicosis).
• Mamwe majini akachinja.
• Kushandisa diuretic therapy kwenguva yakareba yekushaya simba kwemoyo.
• Zvirwere zvekushaya thiamine zvakaita seHIV/AIDS.
• Kutadza kushanda kweitsvo, nekuti kurapwa kwenguva refu kwe dialysis kunoderedza kugona kwemuviri kunwisa thiamine.
• Kushaikwa kwenzvimbo dzekurapa kana chikafu chinovaka muviri.
• Kurutsa zvakanyanya uye kuda kurutsa panguva yekuzvitakura (hyperemesis gravidarum).

Ndezvipi zvikonzero zve 'Wernicke-Korsakoff syndrome'?

Chikonzero chikuru cheizvi kushomeka kwe "Thiamine". Iyi vhitamini inokosha ndiyo inoshandura shuga yatinodya kuita simba. Saka kana tisina "Thiamine" yakakwana, uropi hwedu hahuwani simba rahunoda kuti hushande zvakanaka.

Chikonzero chikuru chekushaikwa kwe thiamine ndecheKunwa doro rakawandisa kwenguva yakareba. Doro rinoita kuti zviomere muviri kunwa thiamine woichengeta muchiropa. Doro rinokanganisawo kushandiswa kwevhitamini B1 kune mamwe mabasa akakosha.

Kune zvimwe zvikonzero zvakare:

• Kudya zvisina kunaka: Kusadya chikafu chakakwana.
• Matambudziko ekudya: akadai seanorexia nebulimia.
• Utachiona husingaperi.
• Kuvhiyiwa: Kunyanya kuvhiyiwa kwakadai sekuvhiyiwa kwemudumbu kuti uderedze uremu.
• Kukuvara kweuropi: Asi izvi hazviwanzoitiki.

Ndezvipi zviratidzo zve 'Wernicke-Korsakoff syndrome'?

Izvi zvinogona kuoneka muzviratidzo zvakasiyana-siyana. Chimwe chezviratidzo zvinowanzoonekwa muzviitiko zvakakomba 'confabulation' . Kureva, kugadzira nyaya mupfungwa dzako kuti uvhare zvinhu zvausingayeuki. Fungidzira, mumwe munhu haayeuki chimwe chinhu chaakaita nezuro, asi anotaura nhema kuti avhare, asi haanyepi nekuti anofunga kuti chakaitika zvechokwadi. Vanotenda nyaya yacho.

Vanhu vane chirwere ichi vanowanzo vhiringidzika kana kuvhiringidzika. Kuvhiringidzika uku kunoita kuti zvivaomere kuziva kuti pane chakaipa pavari uye kuti vatsvage kurapwa.

Zviratidzo zvinowanzoonekwa zveWernicke encephalopathy:

• Kurasikirwa nechiyero kana kutadza kudzora mafambiro (ataxia).
• 'Kusangana'.
• Kuvhiringidzika, kupenga.
• Kufamba zvakaoma, kufamba kusina kugadzikana.
• Kurara.
• Kudzikira kwemuviri zvakanyanya (hypothermia).
• Matambudziko emwoyo: kuwedzera kwekurova kwemoyo (tachycardia) kana kuderera kweBP (hypotension).
• Kurasikirwa nekubatana kwetsandanyama (ataxia).

Matambudziko emaziso anowanzoitikawo:

• Kufamba kwemaziso kusina kujairika (nystagmus).
• Kuona kaviri.
• Kudonha kwemaziso epamusoro (ptosis).
• Kusashanda zvakanaka kwetsandanyama dzemaziso kana kushaya simba (ophthalmoplegia).

Kana Wernicke encephalopathy ikasarapwa, inogona kukura kuita Korsakoff syndrome, chirwere chenguva refu chekuyeuka. Zviratidzo zvayo zvinosanganisira:

• Kurasikirwa zvachose nendangariro (`Amnesia`) kana kutadza kurangarira chero chinhu chitsva.
• Kuchinja kwemaitiro: kushatirwa, hasha dzinokurumidza.
• 'Kusangana'.
• Kuvhiringidzika kwepfungwa uye kuvhiringidzika.
• Kuneta kana kuneta.
• Kufungidzira zvinhu zvisipo, kunyanya kana munhu akarega doro.
• Kusakwanisa kuisa pfungwa pachinhu chimwe nechimwe.
• Kufamba kusina kugadzikana.

Zvimwe zviratidzo hazvinyatsovandudzika kunyangwe kana ukarapwa. Muzviitiko zvakakomba, kurasikirwa nepfungwa ('coma') kunogona kuitika. Kana iwe kana mumwe munhu ari pedyo newe akarasikirwa nepfungwa, kana uine zviratidzo zve'Wernicke-Korsakoff syndrome', ona chiremba kana enda kuchipatara nekukurumidza.

'Wernicke-Korsakoff syndrome' inoonekwa sei?

Kuonekwa kwechirwere ichi che "WKS" nekukurumidza kwakakosha kuti kurapwa kubudirire. Vanachiremba vanochiongorora nekuita bvunzo yemuviri, kubvunza nezvezviratidzo zvako, uye kubvunza nezvenhoroondo yemhuri yako. Zvisinei, zvinogona kuoma kuona kana mumwe munhu akavhiringidzika kana kuti aine ndangariro dzisina kunaka.

Chiremba achaongorora zvinhu izvi zvakananga:

• Pane matambudziko ekushandisa doro here ('Doro rinoshandiswa zvisina kunaka')?
• Kune kushaya chikafu chakakwana here?
• Pane kushomeka kwe thiamine here?

Ndezvipi zviedzo zvinobatsira pakuongorora chirwere cheWernicke-Korsakoff?

Chiremba wako acharaira kuongororwa kweropa kuti aone huwandu hweshuga muropa rako uye thiamine. Vanogonawo kuraira kuongororwa kwedoro muropa kuti vaone kana doro riri kushandiswa uye kuongororwa kwechiropa kuti vaone mashandiro echiropa, sezvo izvi zvingaratidza kukuvara kwechiropa.

Mimwe miedzo inogona kuitwa kuti iongorore zvimwe zvikonzero:

• Kuongororwa kwe'Arterial blood gas' (ABG) kunoongorora huwandu hwecarbon dioxide neoxygen muropa.
• 'Kuverengwa kweropa kwakazara' ('Kuverengwa kweropa kwakazara - CBC`).
• Kuongororwa kwechepfu.

Ungangodawo kuita bvunzo dzemifananidzo dzakadai sedzinotevera:

• 'CT scan'.
• 'MRI' ('MRI`).
• 'Electrocardiogram' ('Electrocardiogram - EKG`).

Ko Wernicke-Korsakoff Syndrome inogona kurapwa here? Inorapwa sei?

Kutaura zvazviri, hazvirapiki zvachose. Zvisinei, kana kurapwa kukatanga nekukurumidza, zviratidzo zvinogona kupera uye zvimwe zvacho zvinogona kugadziriswa. Izvi zvinoreva kuti chirwere chinonzi ``Wernicke encephalopathy`` chinogona kumiswa kubva pakuwedzera kuita ``Korsakoff syndrome``.

Kazhinji, kurapwa kunogona kudzora kana kugadzirisa zviratidzo zvakaita sekuvhiringidzika, matambudziko emaziso, uye kurasikirwa nepfungwa dzakanaka. Chiremba wako achagadzira hurongwa hwekurapa hwakakunakira.

Zvinotevera zvinowanzoitwa sekurapa:

• Kupa vhitamini B1 kuburikidza nemapiritsi kana majekiseni.
• Kana muviri usina mvura mumuviri, isa saline kuburikidza ne "IV fluids".
• Kurapa matambudziko ane chekuita nekushandisa doro.
• Kupa rutsigiro rwezvekudya.
• Ipai mimwe mishonga kana zvichidikanwa.

Ungaderedza sei njodzi yekubatwa nechirwere ichi?

Kazhinji, kurega kana kuderedza kunwa doro ndicho chinhu chakakosha chaunogona kuita kuderedza njodzi yako yekubatwa nechirwere cheWernicke-Korsakoff. Uyewo, kuwana kudya kwakanaka uye, kana zvichidikanwa, kutora mishonga yekuwedzera yethiamine muchimiro chemajekiseni kana mapiritsi kunogona kubatsira kuderedza njodzi yako, kunyanya kune avo vakapindwa muropa nedoro.

Chii chingave chiri fungidziro yemunhu ane chirwere cheWernicke-Korsakoff?

Kana iwe kana mumwe munhu ari pedyo newe aine chirwere ichi, fungidziro yacho inoenderana nekuti zviratidzo zvacho zvakakura sei uye kuti chirwere ichi chinokurumidza kuonekwa uye kurapwa. Kurapwa nekukurumidza kunogona kuchinja zviratidzo uye kudzivirira matambudziko asingaperi. Zvisinei, kana zvikasarapwa, zvinogona kukonzera kuremara uye kunyange rufu.

Unofanira kutsvaga rubatsiro rwechiremba riini panyaya iyi?

Kana iwe kana mumwe munhu waunoziva aine zviratidzo zveWernicke-Korsakoff syndrome, tsvaga rubatsiro rwechiremba nekukasika. Ungangoda kufonera chiremba wako kana kuenda kuchipatara chiri pedyo kuti uwane rubatsiro rwekukurumidzira.

Ndinozvitarisira sei?

Kuongororwa kuti une chirwere cheWernicke-Korsakoff hakusi nyore. Ungangoda kuenda kuchipatara worapwa. Chinhu chakakosha kutevedzera zano rachiremba wako, rakadai sekuderedza kunwa doro (kana kurega zvachose) uye kudya chikafu chinovaka muviri. Zvinhu izvi zvichabatsira zvikuru pakupora kwako.

Tevedzera mirairo yachiremba wako nokungwarira kuti ugadzirise matambudziko uye urape zviratidzo. Iye achagadzira hurongwa hwekutarisira hwakakunakira uye huchakubatsira kuti udzokere pahutano hwako.

Chirwere cheWernicke-Korsakoff chirwere chisingawanzoitiki asi chakakomba chekurangarira. Chinoda kurapwa nekukurumidza kuderedza zviratidzo uye kudzivirira matambudziko. Sezvo chirwere ichi chichienderera mberi, zviratidzo zvetsinga, zvakaita sekuvhiringidzika kwakanyanya uye kuvhiringidzika, zvinoitika. Zviratidzo izvi zvinogona kuita kuti zvikuomere iwe kana mumwe munhu ari pedyo newe kuziva mamiriro ako ezvinhu. Saka, zvakakosha kuongorora chirwere ichi nekukurumidza. Chiremba wako achakurudzira chirongwa chekurapa chakagadzirirwa zvaunoda.

Zvinhu zvakakosha zvekurangarira (Mharidzo Yekuenda Kumba)

Zvakanaka, hezvino zvinhu zvikuru zvekurangarira nezve `Wernicke-Korsakoff Syndrome` yatakataura nezvayo:

• Ichi chirwere chakakomba chinokanganisa uropi nendangariro nekuda kwekushomeka kwe thiamine (vhitamini B1).
• Chinhu chikuru chinokonzera njodzi iyi kunwa doro zvakanyanya.
• Danho rekutanga iWernicke encephalopathy, iyo, kana ikasarapwa, inogona kukonzera dambudziko renguva refu rekuyeuka rinonzi Korsakoff syndrome.
• Kuvhiringidzika, kuoma kufamba, matambudziko ekuona, uye kutadza kuyeuka zvinogona kunge zviri zviratidzo zvikuru.
• Kuongororwa nekukurumidza uye kurapwa nekukurumidza ne thiamine kwakakosha.
• Kunyange hazvo isingarapike zvachose, kurapwa kwekutanga kunogona kudzora zviratidzo uye kudzivirira kukuvara zvachose.
• Kana iwe kana mumwe munhu waunoziva ari kuratidza zviratidzo izvi, tsvaga rubatsiro rwechiremba nekukasika.

Ndinovimba ruzivo urwu ruchakubatsira. Ramba uine hutano hwakanaka!

Wernicke -Korsakoff syndrome, kushomeka kwethiamine, vhitamini B1, kushandiswa kwedoro, kutadza kurangarira, matambudziko europi, zvirwere zvetsinga