Oko kufuneka ukwazi malunga ne-androgens!

Ngaba wakha weva ngee-androgens? Mhlawumbi ewe, mhlawumbi akunjalo. Kodwa liqela lee-hormones ezikhoyo kuyo yonke imizimba yethu kwaye zibaluleke kakhulu kuphuhliso lwethu lwesondo kunye nempilo yethu. Ezi androgens zifana nezinceku ezincinci ezisebenza ngasemva kweziganeko emizimbeni yethu. Namhlanje, siza kuthetha ngazo ngendlela elula onokuyiqonda.

Ngamafutshane, ii-androgens luhlobo lwe-hormone yesini. Zizo ezisenza sikhule, kwaye zikwanceda kwimpilo yenkqubo yethu yokuzala kunye nokukhula kwemizimba yethu. Unokucinga ukuba ngamadoda kuphela anazo. Kodwa eneneni, sonke, nokuba ngamadoda okanye ngabafazi, sine-androgens emizimbeni yethu. Nangona kunjalo, ziveliswa ngokwendalo ngamanani aphezulu kumadoda. I-Testosterone, uninzi lwethu esiye seva ngayo, ikwayi-androgen enkulu.

Ngoku usenokuba uzibuza ukuba la ma-hormone avela phi. Ii-Androgens ziveliswa kakhulu ngama-testicles kwinkqubo yokuzala yamadoda kunye nama-ovari kwinkqubo yokuzala yabasetyhini. Ukongeza, la ma-hormone akwaveliswa ngama-adrenal glands akwizintso zethu. Ii-Androgens azikho apho kuphela. Zenza umsebenzi omkhulu ekugcineni uphuhliso lwethu ngokwesondo kunye nempilo iyonke. Amanqanaba azo anokutshintsha imini yonke. Kwakhona, la manqanaba ee-hormone ayatshintsha kumanqanaba ahlukeneyo ebomini bethu, njengakwixesha lokufikisa kunye nokuya exesheni.

Ziziphi iintlobo ze-androgens ezikhoyo?

Njengoko besitshilo ngaphambili, i-testosterone yeyona androgen iphambili esinayo sonke. Ezinye ii-androgens ezininzi zinceda ekwenzeni ezinye iihomoni. Umzekelo, ezi androgens zilandelayo zinceda ekwenzeni i-testosterone kunye ne-estrogen:

• I-Androstenedione
• I-Dehydroepiandrosterone (DHEA)
• I-DHEA sulfate (DHEA sulfate - DHEAS)

Enye i-androgen yi- dihydrotestosterone (DHT) . Njengoko ukhula, umzimba wakho uguqula malunga ne-10% ye-testosterone yakho ibe yi-DHT yonke imihla. Ukongeza, kukho ezinye iintlobo ezininzi ze-androgen kunye neekhemikhali ezininzi ezinxulumene ne-androgen. Indlela imizimba yethu esebenzisa ngayo ezi hormone iyinkimbinkimbi kakhulu, njengomatshini omkhulu.

Yeyiphi inkonzo enikezelwa yi-androgens emizimbeni yethu?

I-Androgens kuthi sonke, kungakhathaliseki ukuba singobani na ngokwesini, isinceda kwezi zinto:

• Uxinano lwamathambo: Oku kubalulekile ukuze amathambo ethu ahlale eqinile.
• Uphuhliso lwezihlunu: Ezi zikwafuneka ekukhuleni kwezihlunu .
• Ukufikisa: Ezi ziinguqu ezisisiseko ezenzeka ukususela ebuntwaneni ukuya ebuntwini obukhulu.
• Ukuveliswa kweeseli ezibomvu zegazi (i-Erythropoiesis): Ikwanceda ekuvelisweni kweeseli ezibomvu zegazi emizimbeni yethu.
• Umnqweno wesondo kunye nomsebenzi: Ezi zichaphazela uphuhliso lweemvakalelo zesondo kunye nemisebenzi yesondo.

Kwenzeka ntoni ngokukodwa kumadoda ane-androgens?

I-Androgens emzimbeni wendoda inegalelo ku:

• Ilizwi elinzulu (ukwandiswa kwelizwi): Ilizwi elithambileyo owawunalo xa wawusengumntwana liyatshintsha, kwaye ilizwi lobudoda liyavela ngenxa yoku. Khawuthelekelele, unyana womhlobo wakho utshintsha ilizwi lakhe ngequbuliso, uze ucinge, "Mzalwana, sele ekhulile ngoku," akunjalo? Isizathu soko yi-androgens.
• Ukuba mde: Ezi hormone zikwachaphazela nobude.
• Ukukhula kweenwele ebusweni, entlokweni, esifubeni, emakhwapheni, nakwiindawo zangasese: Izinto ezinje ngokukhula kweendevu kunye nokukhula kweenwele esifubeni.
• Uphuhliso lwesidoda: Ezi zibalulekile ekuveliseni isidoda esifunekayo ukuze umntwana abe ngumntwana.

Ezi mpawu zomzimba ziqala kakhulu ngexesha lokufikisa. Kodwa i-testosterone inemisebenzi eyahlukeneyo kumanqanaba ahlukeneyo obomi. Njengoko usiba ngumntu omdala, amanqanaba akho e-testosterone ayancipha ngokwendalo njengoko ukhula.

Ii-androgens zichaphazela njani abafazi?

Kwabasetyhini, ezinye iikhemikhali zomzimba ziguqula i-androgen testosterone ibe yi -estradiol, uhlobo lwehomoni ye-estrogen . Le estradiol:

• Uphuhliso lweempawu zesondo zesibini ngexesha lokufikisa: umzekelo, uphuhliso lwamabele kunye nokwandiswa kwamaqakala.
• Ilawula ukuya exesheni: Inceda ukugcina umjikelo wexesha eliqhelekileyo wokuya exesheni.
• Inceda ekukhulelweni nasekukhulelweni: Ezi zinto zibalulekile ekukhulelweni komntwana nasekukhulelweni ngempumelelo.
• Inciphisa ukulahleka kwamathambo - I-Osteoporosis: Inceda ekunciphiseni umngcipheko we- osteoporosis , imeko eyenzeka xa amathambo ewohloka, ingakumbi njengoko sikhula.

Amanqanaba e-estradiol emzimbeni wakho ayatshintsha kumanqanaba ahlukeneyo ebomini bakho. Emva kokuya exesheni, apho ixesha lakho lenyanga liyema khona, umzimba wakho awuvelisi i-estradiol engako.

Ziziphi iingxaki amadoda anazo nge-androgens?

Amadoda adla ngokuchaphazeleka kakhulu yimeko ebizwa ngokuba yi -male hypogonadism, ebangelwa kukwehla kwamanqanaba e-androgen, okanye amanqanaba e-testosterone. Oku kunokukhokelela ekunciphiseni umnqweno wesondo kunye nokungasebenzi kakuhle kwe-erectile.Iimpawu ezinje: Ukuba unento efana nale, kubaluleke kakhulu ukuthetha nogqirha ngaphandle kokuyigcina kuwe okanye ukhathazeke.

Kwabanye abantu, ii-androgens zinokubangela ukuba kubekho umhlaza we-prostate . Kwiimeko ezinjalo, kunokufuneka uthathe amayeza okunciphisa imveliso yendalo yomzimba yee-androgens. Oogqirha babiza olu nyango ngokuba yi-Androgen Deprivation Therapy (ADT) .

IiAndrogens – ingakumbi i-DHT (i-Dihydrotestosterone) – zikwanxulunyaniswa nokuba nebala elifana nelamadoda , imeko ebizwa ngokuba yi-androgenic alopecia . Ezi hormone zikwanegalelo ekubeni nebala elifana nelamadoda abantu abaninzi abalibiza ngokuba yi-'waxiness'.

Ziziphi iingxaki abanazo abafazi nge-androgens?

Abafazi bachaphazeleka kakhulu ziingxaki zokunyuka kwamanqanaba e-androgen (hyperandrogenism) . Eyona nto ibangela oku yimeko ebizwa ngokuba yiPolycystic Ovary Syndrome (PCOS) . Le PCOS yinto ebonwa phakathi kwabasetyhini abaninzi kule mihla. Ubusazi ukuba i-PCOS ngamanye amaxesha inokubangela ukulibaziseka kokukhulelwa? Amaxesha amaninzi, amanqanaba e-androgen anokunyuka ngenxa yeethumba kwi-adrenal glands okanye kuma-ovari.

Abantu abane-PCOS, okanye abo banamanqanaba aphezulu e-androgens, banokufumana iimpawu ezifana nezi:

• Iimpundu: Iimpundu zivela ebusweni, esifubeni, nasemqolo. Ngamanye amaxesha ezi impundu zinokuba yinto ecaphukisayo.
• I-Amenorrhea okanye ukuya exesheni ngokungacwangciswanga: Ukuya exesheni okungenzeki ngexesha elifanelekileyo, okanye okulibaziseka kangangeenyanga.
• Ukukhula kweenwele ngokugqithisileyo (i-hirsutism): Ukukhula kweenwele okungafunekiyo esilevini, esifubeni, nasesiswini, njengendevu. Oku kunokuchaphazela abafazi abaninzi ngokwengqondo.
• Uxinzelelo lwegazi oluphezulu kunye ne-cholesterol ephezulu.
• Ubunzima bokufumana abantwana (Ukungazali).
• Ukutyeba kakhulu: Ukuba nobunzima obukhulu.

I-Androgens – ingakumbi i-DHT (i-Dihydrotestosterone) – inokuchaphazela nokuba neenwele ezinde kwabasetyhini. Abanye abafazi banengxaki yokulahlekelwa ziinwele ezingaqhelekanga kunye nokuba nentloko enesihlunu, akunjalo? Le hormone nayo inempembelelo kuloo nto.

Ziziphi iingxaki ezinokuvela ngenxa yamanqanaba e-androgen kubantwana abancinci?

Iingxaki ngamanqanaba e-androgen ebantwaneni zinokubangela ukuba bafikise ixesha elide okanye bafikise ngaphambi kwexesha.Ewe, kunokwenzeka. Zininzi izizathu zokuba kubekho esinye sezizathu. Umzekelo, abanye abantwana babonisa iimpawu zokufikisa kwangethuba kakhulu kunabanye. Kwaye abanye abantwana abafikisi kwangethuba nangona sele befikelele ekufikiseni. Zombini ezi ziimeko ezifuna unyango.

Amanqanaba e-androgen akwanxulunyaniswa neemeko ezibizwa ngokuba ziingxaki zophuhliso lwesondo . Oku kubhekisa kwiqela leemeko ezahlukeneyo ezimalunga nama-60 apho umntu eneempawu zobudoda nezebhinqa. Ezi ziimeko ezinzima kancinci, ngoko ke zifuna ingqalelo ekhethekileyo koogqirha.

Oogqirha balinganisa njani amanqanaba e-androgen?

Ukujonga ukuba umfazi unezinga eliphezulu le-androgen, oogqirha badla ngokusebenzisa uvavanyo olubizwa ngokuba yiFree Androgen Index (FAI) . I-FAI ilinganiswa ngokuthatha isampuli yegazi kunye nokulinganisa oku kulandelayo:

• I-testosterone iyonke
• I-testosterone yasimahla
• I-globulin ebopha i-sex-hormone (SHBG)

I-SHBG yiproteni ethwala ii-androgens (ezifana ne-testosterone kunye ne-DHT) kunye ne-estrogen egazini. Ugqirha wakho uza kubala amanqanaba akho e-androgen ngokuthelekisa amanqanaba akho e-testosterone kunye ne-SHBG.

Kumadoda, oogqirha badla ngokuyalela uvavanyo lwegazi lwe-testosterone ukujonga amanqanaba e-testosterone aphantsi.

Kodwa khumbula, olu vavanyo lwegazi lodwa alunakukuxelela yonke into. Ugqirha wakho uza kwenza isigqibo ngokusekelwe kwizinto ezininzi, kuquka iimpawu zakho kunye novavanyo lwezonyango.

Ngoko ke, sithini isigidimi esifanele sisithathe ekhaya kuko konke oku?

IiAndrogens zibalulekile kwimpilo yokuzala kunye nokuphila kakuhle kwethu sonke, abafazi, amadoda, abancinci nabadala. Kodwa ukuze ezi zisebenze kakuhle, kufuneka kubekho ibhalansi efanelekileyo . Njengesikali, ukuba sinzima kakhulu kwelinye icala, kukho ingxaki. Ukuba sincinci kakhulu, kukho ingxaki; xa sininzi kakhulu, kukho ingxaki.

Ukuba uneempawu ze-androgen ephantsi okanye ephezulu, umzekelo, njengoko bekutshiwo ngaphambili, ukungabikho komnqweno wesondo, ubunzima bokuqina kwamadoda, ukuya exesheni okungacwangciswanga, ukukhula kweenwele ngokugqithisileyo, i-acne kwabasetyhini, okanye ukufikisa okulibazisekileyo okanye kwangethuba kumntwana, qiniseka ukuba ubona ugqirha ukuze akunike ingcebiso . Ugqirha unokwenza uvavanyo olufunekayo aze afumanise ukuba yintoni kanye ebangela iimpawu zakho. Ungakhathazeki, zihlala zikho iindlela ezilungileyo zokunyanga oku.

Khumbula, uyayazi kakuhle imizimba yakho. Ukuba ubona naluphi na utshintsho okanye izinto ezingaqhelekanga, kububulumko ukufuna ingcebiso kagqirha kunokungayinaki.

I- Androgens, iTestosterone, iiHormones, Impilo yokuzala, i-PCOS, Impilo yamadoda, Impilo yabasetyhini