Ngaba wakha waziva udiniwe kancinci ngendlela engaqhelekanga, watyeba okanye wancipha umzimba ngequbuliso, okanye watshintsha umbala wolusu? Ngexesha elinje, ukuba ugqirha uthe kuwe, "Masenze uvavanyo lwe-ACTH," usenokuba novalo kancinci. "Luhlobo luni lovavanyo olo?" Usenokuba uzibuza. Ungakhathazeki. Olu luvavanyo lwegazi oluqhelekileyo oluhlala lwenziwa ukujonga iihomoni emzimbeni wethu. Namhlanje, siza kuthetha ngayo yonke into ngendlela elula kakhulu onokuyiqonda.
Kalula nje, yintoni i-ACTH?
Umzimba wethu ngumatshini omangalisayo. Inxalenye nganye yawo inxibelelana ngemiyalezo yamakhemikhali ebizwa ngokuba yi "hormones." Khawuthelekelele ukuba
i-pituitary gland, enobukhulu be-pea kwaye ikwisiseko sobuchopho bethu, ifana nomphathi oyintloko kwiofisi enkulu. Lo mphathi ukhupha umyalezo okhethekileyo obizwa ngokuba yi
-ACTH (i-Adrenocorticotropic hormone) . Lo myalezo uya ngqo kwi-
adrenal glands, ezifana nee-caps ezimbini phezu kwezintso zethu. La ma-adrenal glands afana nomzi-mveliso. Nje ukuba umyalezo we-ACTH uphume kwi-pituitary gland, lo mzi-mveliso uvelisa i-hormone ebalulekileyo ebizwa ngokuba
yi-cortisol .
Kutheni ke le hormone i-cortisol ibalulekile kuthi?
I-Cortisol ayisiyo hormone nje kuphela, inomsebenzi obaluleke kakhulu emizimbeni yethu.
- Inceda ekulawuleni uxinzelelo lwegazi .
- Inika umzimba amandla okulwa nosulelo ngempumelelo .
- Isinceda siqhekeze iswekile , amafutha kunye neeproteni ekutyeni esikutyayo kwaye ivelise amandla .
- Inceda umzimba ukuba ukwazi ukulawula uxinezeleko.
Ngoku uyaqonda ukuba le nkqubo ibaluleke kangakanani? Ukuba umyalezo we-ACTH ovela kwi-pituitary gland uyanda, ii-adrenal glands zivelisa i-cortisol engakumbi. Ukuba i-ACTH iyancipha, nemveliso ye-cortisol iyancipha. Ukuba ugqirha unamathandabuzo malunga nokusebenza kwezi glands zimbini, oko kukuthi, ukuba ufuna ukwazi ukuba amanqanaba e-ACTH okanye e-cortisol aphezulu okanye aphantsi, uya kuyalela olu vavanyo lwe-ACTH.
Okubalulekileyo kukuba, uvavanyo lwe-ACTH ludla ngokwenziwa ngexesha elinye novavanyo lwe-cortisol , njengoko imisebenzi yezi hormone zimbini inxulumene.
Lolu vavanyo lwenzelwa ziphi iimpawu?
Iimpawu ezibangelwa kukungalingani kwehomoni ye-ACTH zinxulumene ngokuthe ngqo nokwanda okanye ukuncipha kwehomoni ye-cortisol. Makhe sibone ukuba zeziphi ezi mpawu.
Iimpawu zamanqanaba aphezulu e-cortisol ngenxa yokwanda kwe-ACTH
| Ukutyeba kwakho | Amanqatha ahlala emzimbeni, ingakumbi ebusweni, ngasemva kwentamo, nasemagxeni. |
| Utshintsho lolusu | Ukubonakala kweempawu zokunwebeka ezipinki okanye ezimfusa esiswini, emathangeni nasemabeleni. |
| Ukubuthathaka | Ubuthathaka bemisipha kunye nokudinwa kakhulu rhoqo. |
| Ezinye iimpawu | Nokuba inxeba elincinci lijika libe luhlaza okwesibhakabhaka ngokukhawuleza, i-acne iyanda, ukukhula kweenwele ezingafunekiyo kubafazi, kunye noxinzelelo lwegazi oluphezulu. |
Iimpawu zamanqanaba aphantsi e-cortisol ngenxa ye-ACTH ephantsi
| Ukuhla ukusinda | Ukunciphisa umzimba nangona usitya kakuhle. |
| Iingxaki zenkqubo yokugaya ukutya | Ukugabha rhoqo, ukugabha, iintlungu zesisu, kunye norhudo. |
| Utshintsho lolusu | Ulusu luba mnyama (luba mnyama) kwezinye iindawo, ingakumbi iingqiniba namadolo. |
| Ezinye iimpawu | Ukusoloko uziva udiniwe kakhulu, unesizungu, kunye nokunqwenela ukutya okunetyuwa. |
Ngokusekelwe kwezi mpawu, ugqirha wakho unokukrokrela ukuba unemeko efana ne
-Cushing's syndrome (i-cortisol eyonyukileyo),
isifo sika-Addison (i-cortisol ehlileyo), okanye ithumba kwi-pituitary gland okanye kwenye indawo. Olu vavanyo lwe-ACTH lubaluleke kakhulu ukuqinisekisa olo krokrelo.
Ufanele uzilungiselele njani ngaphambi kovavanyo?
Ekubeni olu luvavanyo lwegazi, akukho mfuneko yokulungiselela okuninzi. Nangona kunjalo, kukho izinto ezininzi ezinokuchaphazela iziphumo zovavanyo. Ngoko ke,
kubaluleke kakhulu ukulandela imiyalelo kagqirha ngokuchanekileyo.
- IiSteroids: Ukuba uthatha nawaphi na amayeza e-steroid, ugqirha wakho angakucela ukuba uyeke ukuwathatha malunga neeyure ezingama-48 ngaphambi kovavanyo. La mayeza anokutshintsha ngokupheleleyo iziphumo.
- Ukutya Neziselo: Usenokucelwa ukuba uzile ukutya ukususela ezinzulwini zobusuku ngaphambi kovavanyo. Usenokucelwa ukuba unciphise ukutya kwakho iicarbohydrate ( starch ).
- Ukuzilolonga noxinzelelo : Kuphephe ukuzilolonga ngokugqithisileyo okanye uxinzelelo olungeyomfuneko kwiiyure ezili-12 ngaphambi kovavanyo. Ezi zinto zinokuchaphazela amanqanaba eehomoni.
- Lala kamnandi ebusuku: Lala kamnandi ebusuku bangaphambili. Nokuba ungalali ngokwaneleyo kunokuchaphazela iihomoni.
- Yazisa ugqirha wakho malunga nawo onke amayeza: Qiniseka ukuba uxelela ugqirha wakho malunga nawo onke amayeza (aseNtshona, aseAyurvedic, aseSinhala), iivithamini, kunye nezongezo ozisebenzisayo.
Indlela yokwenza uvavanyo kunye neengozi
Le yinkqubo elula kakhulu. Njengesampuli yegazi, umongikazi uza kuthatha isampuli yegazi kumthambo osengalweni yakho. Kodwa kukho into ekhethekileyo apha. Amanqanaba ethu e-ACTH kunye ne-cortisol ayatshintsha ngokuxhomekeke kwixesha lemini.
Amanqanaba e-ACTH adla ngokuba phezulu malunga ne-8 kusasa kwaye
asezantsi ebusuku . Ngoko ke, ukuba ugqirha wakho ufuna ukufumana umfanekiso opheleleyo weehomoni zakho, unokuthatha iisampuli zegazi kanye kusasa aze aphinde athathe ngokuhlwa okanye ebusuku. Emva kokuba igazi lithathiwe, iisampuli zifakwa ngoko nangoko emkhenkceni zize zithunyelwe kwilebhu. Oku kungenxa yokuba i-ACTH yihomoni enokutshatyalaliswa ngokukhawuleza. Ngokuphathelele iingozi, kukho iingozi eziqhelekileyo zalo naluphi na uvavanyo lwegazi. Kunokubakho ubuhlungu apho inaliti ifakwe khona, ukukrweleka okuthile, kwaye kunqabile kakhulu, usulelo. Akukho nto yokukhathazeka ngayo.
Ungaziqonda njani iziphumo?
Iziphumo zengxelo yakho zinokwahluka kancinci kwilebhu nganye. Inqanaba eliqhelekileyo le-ACTH kumntu omdala osempilweni, elilinganiswa ngentsimbi yesi-8 kusasa, kufuneka libe phakathi kwe-10 kunye ne-50 picograms nge-milliliter (pg/mL). Nangona kunjalo,
musa ukuba ngugqirha kwaye wenze izigqibo zakho ngokusekelwe kwingxelo . Kukho ezinye izinto ezininzi ezinokuchaphazela ezi ziphumo.
- Ngaba ulale kakuhle ngosuku olungaphambi kovavanyo?
- Ngaba ubuxinezelekile?
- Amanye amayeza owasebenzisayo (umz. i-insulin, iipilisi zehomoni).
- Ukuba ngumfazi, ngumhla womjikelo wakhe wokuya exesheni.
- Ingozi okanye ingozi yakutshanje.
- Nokuba isampuli yegazi iqokelelwe ngokufanelekileyo, igcinwe emkhenkceni, kwaye igcinwe.
Ucinga ngako konke oku, ugqirha wakho uza kujonga iziphumo zakho ze-ACTH kunye neziphumo zakho ze-cortisol kunye. Abayi kwenza isigqibo ngokusekelwe kwisiphumo esinye kuphela. Ukuba inqanaba lakho le-ACTH liphezulu kwaye inqanaba lakho le-cortisol nalo liphezulu, oko kuthetha into enye. Ukuba inqanaba lakho le-ACTH liphezulu kwaye inqanaba lakho le-cortisol liphantsi, oko kuthetha enye into. Ngoko ke, wakuba ufumene iziphumo zakho, zithathe uhambe nazo ukuya kubona ugqirha wakho. Nguye oza kukuqwalasela konke oku aze akuxelele ngqo ukuba imeko yakho injani kwaye wenze ntoni emva koko. Banokuyalela iimvavanyo ezingaphezulu ukuqinisekisa ezi ziphumo.
Umyalezo Wokuya Ekhaya
- Uvavanyo lwe-ACTH luvavanyo lwegazi olulinganisa ihomoni ekhutshwa yi-pituitary gland engqondweni yethu. Lunokusixelela nangokusebenza kwamadlala e-adrenal.
- Olu vavanyo ludla ngokwenziwa kunye novavanyo lwehomoni ye-cortisol.
- Ugqirha angacebisa olu vavanyo ukuba uneempawu ezifana nokutshintsha kobunzima obungachazwanga, ukudinwa kakhulu, okanye utshintsho lolusu.
- Kubaluleke kakhulu ukuba iziphumo zichaneke ukulandela imiyalelo kagqirha (malunga nokutya, amayeza, kunye nokuzilolonga) ngaphambi kovavanyo.
- Emva kokufumana ingxelo yovavanyo, musa ukuzenzela izigqibo ngokusekelwe kwixabiso. Qiniseka ukuba uyibonisa ugqirha wakho ingxelo ukuze afumane uhlalutyo oluchanekileyo kunye nengcebiso.
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