Oko kufuneka ukwazi malunga novavanyo lwe-ACTH

Ngaba ugqirha wakho ukuxelele ukuba wenze uvavanyo lwe-ACTH? Usenokuba novalo kancinci xa usiva igama. Usenokuba ucinga, "Luhlobo luni lovavanyo olungaqhelekanga olu?" Kodwa akukho mfuneko yokoyika. Luvavanyo lwegazi olulula kakhulu. Namhlanje, siza kuthetha ngovavanyo lwe-ACTH, isizathu sokuba lwenziwe, kunye nendlela yokululungiselela ngendlela elula kakhulu onokuyiqonda.

Kalula nje, yintoni i-ACTH?

Kulungile, masicinge ngale ndlela. Umzimba wakho ufana nenkampani enkulu. Kukho izinto ezininzi ezibalulekileyo ezenzekayo kule nkampani.

• Umphathi Oyintloko: Phantsi kwengqondo yakho, kukho idlala elincinci elilingana ne-pea encinci. Silibiza ngokuba yi-pituitary gland. Lo ngumphathi oyintloko webali lethu.
• Umyalezo: Lo mphathi, i-pituitary gland, uthumela umyalezo okhethekileyo. Loo myalezo yinto esiyibiza ngokuba yi-ACTH (i-Adrenocorticotropic hormone).
• Umsebenzi: Lo myalezo we-ACTH uya ngqo kumadlala amabini amancinci aphezu kwezintso zakho. Siwabiza ngokuba ngamadlala e-adrenal. La ngabasebenzi bebali lethu.
• Imveliso: Xa ifumana umyalezo we-ACTH, la madlala e-adrenal avelisa i-hormone ebaluleke kakhulu ebizwa ngokuba yi-cortisol.

Ngoko ke i-ACTH yi-hormone esixelela ukuba senze i-cortisol. Le hormone ye-cortisol ibaluleke kakhulu emizimbeni yethu. Isinceda silawule uxinzelelo lwethu lwegazi , siphendule ngokufanelekileyo kwiintsholongwane , kwaye isincede siqhekeze iishukela, amafutha, kunye neeproteni ekutyeni esikutyayo zibe ngamandla .

Uyaqonda ngoku? Ukuba ugqirha wakho ukrokrela ukuba kukho into engalunganga kule nkqubo, uza kukucela ukuba uhlole igazi ukuze ujonge amanqanaba akho e-ACTH kunye ne-cortisol.

Kutheni ugqirha angacebisa olu vavanyo?

Uvavanyo lwe-ACTH alusoloko lwenziwa lodwa. Phantse luhlala lwenziwa kunye novavanyo lwe-cortisol. Oku kungenxa yokuba iimpawu esizifumanayo xa amanqanaba e-ACTH ephezulu okanye ephantsi zinxulumene ngokuthe ngqo notshintsho kumanqanaba e-cortisol.

Ngoku makhe sibone ukuba zeziphi ezi mpawu.

Ngokujonga ezi mpawu nokuvavanya amanqanaba akho e-ACTH kunye ne-cortisol, ugqirha wakho unokufumanisa ukuba unayo nayiphi na kwezi meko zilandelayo:

• I-Cushing's syndrome: Amanqanaba aphezulu e-cortisol emzimbeni.
• Isifo sika-Addison: Amanqanaba e-cortisol aphantsi kakhulu emzimbeni.
• Nokuba kukho ithumba kwi-pituitary gland okanye kwenye indawo .
• Nokuba i-pituitary glands okanye i-adrenal glands yakho ayisebenzi kakuhle.

Ungazilungiselela njani uvavanyo?

Ukuze ufumane iziphumo ezichanekileyo kolu vavanyo, kufuneka ulungiselele kancinci. Landela la manyathelo ngokuchanekileyo.

• IiSteroids: Ukuba usebenzisa ii-steroids (umz. iPrednisolone), kuya kufuneka uyeke ukuzisebenzisa malunga neeyure ezingama-48 ngaphambi kovavanyo. La mayeza anokuchaphazela iziphumo. Nangona kunjalo, ungaze uyeke ukuwasebenzisa ngaphandle kokubonisana nogqirha wakho kuqala. Uza kukunika ingcebiso ngale nto.
• Ukutya Neziselo: Ugqirha wakho angakuxelela ukuba ungatyi okanye ungaseli nto emva kweentsuku ezimnyama ebusuku ngaphambi kovavanyo. Ngamanye amaxesha, angakuxelela nokuba unciphise ukutya okune-carbohydrate eninzi (iitatshi) kangangeentsuku ezimbini ngaphambi kokuba kwenziwe uvavanyo.
• Lala kamnandi: Lala kamnandi ebusuku ngaphambi kovavanyo.
• Ukuzilolonga: Kuphephe ukuzilolonga okunzima iiyure ezili-12 ngaphambi kovavanyo.
• Uxinzelelo: Zama ukuphumla kangangoko unako. Kuphephe ukuxinezeleka kakhulu iiyure ezili-12 ngaphambi kovavanyo.

Indlela yokwenza uvavanyo kunye neengozi

Oku kulula kakhulu. Njengokunikela ngegazi okuqhelekileyo, umongikazi uza kuthatha isampuli encinci yegazi kumthambo osengalweni yakho.

Ngenxa yokuba amanqanaba ethu eehomoni ayatshintsha imini yonke, ugqirha wakho unokuyalela uvavanyo lwegazi kube kanye kusasa aze aphinde afune uvavanyo ngokuhlwa . Amanqanaba e-ACTH adla ngokuba phezulu malunga nentsimbi yesi-8 kusasa aze anciphe ngokuhlwa. Olu vavanyo luphindwe kabini lunceda ugqirha wakho ukuba afumane umfanekiso opheleleyo.

Emva kokuba igazi litsaliwe, isampuli ibekwa ngoko nangoko emkhenkceni ize ithunyelwe kwilebhu.

Iingozi zizinto eziqhelekileyo zokutsalwa kwegazi ngenaliti. Oko kuthetha intlungu encinci kwindawo yenaliti, ukukrweleka kancinci, okanye, kunqabile kakhulu, usulelo.

Ungaziqonda njani iziphumo?

Amaxabiso akwingxelo yovavanyo lwakho anokwahluka kancinci ukusuka kwilabhoratri ukuya kwenye. Iziphumo ziyahluka ngokuxhomekeke kwixesha lokutsalwa kwegazi.

Ngokwesiqhelo, amanqanaba e-ACTH kumntu omdala ophilileyo aphakathi kwe-10-50 pg/mL (ii-picograms nge-milliliter) malunga ne-8 kusasa. Ngobusuku, oku kwehla kuye ngaphantsi kwe-5-10 pg/mL.

Kodwa musa ukutsiba ufikelele kwizigqibo ngokusekelwe kula manani. Ezinye izinto zinokuchaphazela iziphumo zakho.

• Indlela olale ngayo ngobusuku bangaphambi kovavanyo.
• Uxinezeleko oluphantsi kwakho.
• Nokuba ukhulelwe okanye usexesheni.
• Amanye amayeza owasebenzisayo (umz. iihomoni, i-insulin, ii-steroids).
• Ingozi okanye ukwenzakala emzimbeni kutshanje.
• Nokuba isampuli yegazi iqokelelwe kakuhle kwaye igcinwe emkhenkceni.

Ugqirha wakho uza kuthelekisa ingxelo ye-ACTH nengxelo ye-cortisol aze ayidibanise neempawu zakho ukuze afikelele kwisigqibo sokugqibela. Ukuba kukho into engaqhelekanga kwinqanaba lakho le-ACTH, unokuyalela iimvavanyo ezongezelelweyo ukuze kuchongwe unobangela ochanekileyo.