Xa ugqirha wakho ekuxelela ukuba unesifo seswekile, iyeza lokuqala oza kulinikwa yiMetformin. Eli liyeza elidumileyo nelikhuselekileyo lesifo seswekile, kungekuphela nje eSri Lanka, kodwa kwihlabathi liphela. Nangona kunjalo, kuqhelekile ukuba sonke sibe nemibuzo embalwa kunye noloyiko xa siqala iyeza elitsha. Usenokuba uzibuza izinto ezinje, "Kuza kwenzeka ntoni ngale nto?", "Ingaba oku kulungile emzimbeni?", "Ngaba kukho naziphi na iziphumo ebezingalindelekanga?" Ungakhathazeki, namhlanje siza kuthetha ngolu hlobo lwamayeza olubizwa ngokuba yiMetformin, oko kukuthi, iBiguanides, ngendlela elula kakhulu onokuyiqonda.
Ngamafutshane, ziintoni ezi Biguanides?
IiBiguanides ludidi lwamayeza asetyenziselwa ukulawula isifo seswekile. Zithathwa ngendlela yeepilisi. Zisetyenziswa kakhulu ukunyanga abantu abanesifo seswekile sohlobo lwesibini . Umsebenzi ophambili wala mayeza kukunciphisa nokulawula inqanaba leswekile, okanye iglucose, egazini lakho.
Ngoku usenokuba ucinga, "Ngaba kukho amayeza amaninzi kwiqela leBiguanides?" Akunjalo ngokwenene. Okwangoku, kumazwe amaninzi ehlabathi, kuquka neSri Lanka, kukho ichiza elinye kuphela phantsi kweli qela. Le yiMetformin esiyaziyo sonke. Nangona kunjalo, ungayibona ichiza iMetformin phantsi kwamagama eempawu ezahlukeneyo. Umzekelo:
- I-Glucophage®
- I-Glucophage XR®
- I-Glumetza®
- IFortamet®
- I-Riomet®
Kungakhathaliseki ukuba inaliphi igama, isithako esisebenzayo ngaphakathi siyafana, esiyiMetformin.
Ngaba i-metformin inikwa kuphela abantu abanesifo seswekile?
I-Metformin ivunyiwe kakhulu kwisifo seswekile sohlobo lwesibini. Enyanisweni, ithathwa njengonyango lokuqala kuloo nto. Oko kukuthi, liyeza lokuqala ugqirha aza kuqala ngalo kwangoko nje ukuba isifo seswekile sifunyenwe.
Nangona kunjalo, oogqirha banika eli yeza kwezinye iimeko ezininzi, kungekuphela nje kwesifo seswekile. Oku sikubiza ngokuba "kukusetyenziswa okungekho kwileyibhile". Oko kukuthi, oogqirha banika eli yeza kwezinye iimeko ngaphandle kwaleyo ivunyiweyo ngokusemthethweni, ngenxa yokusebenza kwalo.
| Imeko/ukusetyenziswa kwezonyango | Ingcaciso elula |
|---|---|
| Uhlobo lwesibini lwesifo seswekile | Olu lolona setyenziso luphambili noluvunyiweyo ngokusemthethweni: ukulawula amanqanaba eswekile egazini. |
| I-prediabetes | Libazisa okanye uthintele ukukhula kwesifo seswekile kubantu abasengozini yokufumana isifo seswekile. |
| Isifo Seswekile Sokukhulelwa | Ukulawula isifo seswekile esibangelwa ngabanye oomama ngexesha lokukhulelwa. |
| I-Polycystic ovary syndrome (i-PCOS) | Ukulawula iingxaki (ukungahlali exesheni rhoqo, ukutyeba) ezibangelwa yile meko yamahomoni kubafazi. |
| Amanye amayeza engqondo abangela ukutyeba | Ukulawula ukutyeba okunokubangelwa ngamayeza anikwa ezinye izifo zengqondo. |
Ukongeza, abaphandi ngoku baphanda ukuba ingaba i-metformin inazo na iimpawu zokulwa nomhlaza. Ezinye izifundo zibonise ukuba abantu abasebenzisa i-metformin yesifo seswekile banomngcipheko omncinci wokuba nomhlaza. Nangona kunjalo, ezi zisesekwinqanaba lophando.
Isebenza njani le pilisi yeMetformin emzimbeni wethu?
Lo ngumbuzo obaluleke kakhulu. Zimbini iindlela eziphambili ezisebenza ngazo eli yeza. Masiwuqonde ngomzekelo olula.
Khawuthelekelele ukuba unefektri enkulu emzimbeni wakho eyenza iswekile (iglucose). Eso sisibindi sakho. Kumntu onesifo seswekile, le fektri isebenza kakhulu, isoloko ifaka iswekile egazini.
1. Ukunciphisa ukuveliswa kweswekile sisibindi: Into yokuqala eyenziwa yiMetformin kukunciphisa ukuveliswa kweswekile kwifektri yeswekile (isibindi). Ngamanye amazwi, eli yeza lilawula ukongezwa kweswekile egazini elivela kwisibindi ngokungeyomfuneko.
2. Izihlunu ziya zivakalelwa ngakumbi yi-insulin: Into yesibini kukunceda i-hormone ye-insulin emzimbeni wethu isebenze kakuhle. I-insulin ifana nesitshixo seengcango zeeseli zomzimba wethu. Esi sitshixo sivumela iswekile egazini ukuba ingene kwiiseli kwaye yenze amandla. Abantu abanesifo seswekile banengxaki yokuvula esi sitshixo. Sisibiza ngokubaUkuxhathisa i-insulin. I-Metformin isebenza ngokwenza iingcango zemisipha efana neeseli zamkele ngakumbi esi sitshixo (i-insulin). Emva koko iswekile egazini inokungena lula kwiiseli ize iguqulwe ibe ngamandla. Emva koko inqanaba leswekile egazini liyehla.
Ngamafutshane, into eyenziwa yiMetformin kukunciphisa ukuveliswa kweswekile ngokungeyomfuneko emzimbeni kwaye incede umzimba ukuba usebenzise i-insulin enayo ngokupheleleyo.
Kwabasetyhini abane-PCOS, iMetformin yehlisa amanqanaba e-insulin, nto leyo enciphisa amanqanaba eehomoni ezifana ne-androgens, nto leyo enceda ukubuyisela imijikelo eqhelekileyo yokuya exesheni.
Zithini iingenelo zale yeza?
I-Metformin sisiyobisi esisebenza kakuhle kakhulu.
- Ukwehlisa amanqanaba e-A1C: Kumntu onesifo seswekile, i-metformin inokwehlisa amanqanaba ayo e-A1C (uvavanyo olubonisa amanqanaba aphakathi eswekile egazini kwiinyanga ezi-2-3 ezidlulileyo) malunga ne-1%. Olu luphumelelo olukhulu ekulawuleni isifo seswekile.
- Ukuthintela isifo seswekile: Izifundo zibonise ukuba eli yeza linokunceda ukulibazisa okanye ukuthintela ngokupheleleyo ukukhula kwesifo seswekile esipheleleyo kubantu abanesifo seswekile esingaphambi kokuba sivele.
- Ukunciphisa umngcipheko wesifo sentliziyo: Ezinye izifundo zibonise ukuba i-metformin inokunciphisa nomngcipheko wesifo sentliziyo.
Eyona nto ibalulekileyo kukuba ekubeni eli yeza liyimeko yobomi bonke, kubalulekile ukuhlala unxibelelana nogqirha wakho kwaye uthathe amayeza akho kunye notshintsho kwindlela ophila ngayo (ukutya, umthambo) njengoko kuyalelwe. Amayeza ewodwa awakwazi ukulawula isifo seswekile.
Masiqaphele nemiphumo emibi kunye neengozi.
Njengalo naliphi na iyeza, iMetformin inokubangela ezinye iziphumo ebezingalindelekanga. Kodwa uninzi lwazo azibi zibi kwaye ayinguye wonke umntu ozifumanayo.
Iziphumo ebezingalindelekanga eziqhelekileyo
Ezi zinokwenzeka kwiintsuku zokuqala okanye kwiiveki emva kokuqala amayeza. Zihlala ziphela ngokuhamba kwexesha njengoko umzimba uqhelana namayeza.
- Ukuphazamiseka kwesisu: Ukudumba, isicaphucaphu, ukuhlanza, kwaye ingakumbi urhudo zezona ziphumo zixhaphakileyo. Le meko inokwenzeka kubantu abamalunga nama-30% abasebenzisa i-metformin.
- Ukusela amayeza emva kokutya: Eyona ndlela ilungileyo yokunciphisa ukungakhululeki esiswini ngolu hlobo kukuthatha amayeza xa usitya okanye emva nje kokutya. Musa ukuwasela ungenanto esiswini.
Iziphumo ebezingalindelekanga ezingaqhelekanga
- Ukungonwabi esifubeni
- Intloko ebuhlungu
- Ukubila okugqithisileyo (i-diaphoresis)
- Iswekile ephantsi egazini (i-hypoglycemia) - (Oku kunqabile kakhulu xa usebenzisa i-metformin yodwa, kodwa kunokwenzeka xa ithathwa kunye namanye amayeza eswekile)
- Ubuthathaka
Ukuba ezi zinto ziyaqhubeka okanye zibangela ukungakhululeki, thetha nogqirha wakho.
Iimeko zomngcipheko ezifuna ingqwalaselo ekhethekileyo
I-Metformin ngokubanzi liyeza elikhuselekileyo kakhulu, kodwa kubalulekile ukuqaphela ezinye iingxaki ezinkulu ezinokwenzeka rhoqo.
1. Ukunqongophala kweVithamin B12
Xa usela iMetformin ixesha elide, umzimba wakho usenokufunxa ivithamin B12 kancinci. Ke ngoko, ugqirha wakho unokujonga amanqanaba evithamin B12 yakho, ingakumbi ukuba une-anemia okanye i-peripheral neuropathy. Ukuba kuyimfuneko, unokucebisa ukuba uthathe isongezelelo sevithamin B12.
2. I-Lactic Acidosis
Le yeyona ngxaki ibalulekileyo nenzulu, kodwa ingaqhelekanga, ekufuneka uyazi malunga neMetformin.
I-lactic acidosis yimeko apho umzimba uqokelela i-lactic acid eninzi kakhulu, nto leyo ebangela ukuba igazi libe ne-asidi eninzi kakhulu. Le meko ichaphazela malunga nomntu omnye kwabangama-30,000 abasebenzisa i-metformin. Oku kunqabile kakhulu. Nangona kunjalo, kunokuba yingozi ebomini, ngoko ke kubalulekile ukuba uqaphele iimpawu.
Abantu abasengozini enkulu yokufumana i-lactic acidosis:
- Abantu abanesifo sezintso okanye sesibindi
- Abantu abangaphezu kweminyaka engama-65 ubudala
- Abantu abasandula utyando
- Abantu abane-hypoxia (ukungabikho komoya-mpilo emzimbeni)
- Abantu abasela utywala kakhulu
Ugqirha wakho uza kujonga rhoqo ukusebenza kwezintso zakho xa ekunika iMetformin ukuze aqwalasele le ngozi.
Iimpawu ze-lactic acidosis:
Ukuba kuvela olunye okanye ngaphezulu kwezi mpawu ngequbuliso, yeka ukuthatha amayeza ngoko nangoko uze uye kwigumbi likaxakeka lesibhedlele elikufutshane (ETU).
- Ukudinwa kakhulu kunye nobuthathaka
- Isicaphucaphu nokuhlanza
- Isisu esibuhlungu
- Ukuphefumla okunzulu okanye okukhawulezayo
Le meko ingakhokelela ekufeni ukuba ayinyangwa ngokukhawuleza, ngoko ke ziqaphele ezi mpawu.
3. Iingxaki ngamanye amayeza (Ukusebenzisana kwamayeza)
Ukuba usebenzisa i-metformin kwaye usebenzisa amanye amayeza ngenxa yesinye isifo, kubalulekile ukuxelela ugqirha wakho. Amanye amayeza anokusebenzisana ne-metformin aze anyuse umngcipheko we-lactic acidosis. Amanye amayeza anokubangela iswekile ephantsi egazini (i-hypoglycemia). Qiniseka ukuba uxelela ugqirha wakho ngawo onke amayeza owasebenzisayo (kuquka iivithamini, izongezo, kunye namayeza emifuno).
Ndifanele ndimbone nini ugqirha?
Xa usebenzisa i-metformin, kufuneka uye kwiikliniki ngamaxesha amiselweyo njengoko ugqirha wakho emisele. Ngale ndlela, unokubona ukuba iyeza liyasebenza na, ukuba idosi kufuneka itshintshwe na, kwaye ukuba kukho naziphi na iziphumo ebezingalindelekanga.
Ukongeza, thetha nogqirha wakho kwezi meko zilandelayo:
- Ukuba iziphumo ebezingalindelekanga ziyakukhathaza okanye kunzima ukuzinyamezela.
- Ukuba uvakalelwa kukuba isifo sakho seswekile okanye imeko ye-PCOS ayilawulwa ngokufanelekileyo ngamayeza.
- Ukuba uziva ngathi kufuneka uyeke ukusebenzisa amayeza nangasiphi na isizathu, ungaze uyeke ukuwasebenzisa ngaphandle kokubonisana nogqirha wakho.
I-Metformin liyeza elikhuselekileyo nelisebenzayo elisetyenziswe zizigidi zabantu kwihlabathi liphela amashumi eminyaka, liphandwe kakuhle, kwaye liyanyamezela. Ngoko ke ungoyiki ukubuza imibuzo. Zive ukhululekile ukuthetha nogqirha wakho ngayo nayiphi na imibuzo okanye iinkxalabo onokuba nazo. Uhlala ekulungele ukukunceda.
Umyalezo Wokuya Ekhaya
- I-Metformin liyeza eliqhelekileyo, elikhuselekileyo, nelisebenzayo kwiimeko ezifana nesifo seswekile kunye ne-PCOS.
- Oku kusebenza kakhulu ngokunciphisa ukuveliswa kweswekile sisibindi kwaye kwandisa uvakalelo lomzimba kwi-insulin.
- Iziphumo ezingezizo ezinje ngokudumba kwesisu zinokubakho ekuqaleni, kodwa zinokuncitshiswa ngokuthatha amayeza kunye nokutya.
- I-lactic acidosis yingxaki engaqhelekanga kodwa enzima. Qaphela iimpawu zayo (ukudinwa kakhulu, iintlungu zesisu, ukuphefumla ngokukhawuleza). Ukuba iimpawu ezinjalo ziyavela, yiya kwi-ETU ngoko nangoko.
- Yazisa ugqirha wakho ngazo zonke ezinye iziyobisi ozisebenzisayo.
- Ungaze uqale okanye uyeke ukuthatha iMetformin ngaphandle kwengcebiso kagqirha.
💬 Comments (0)
Akukho zimvo zithunyelweyo okwangoku. Faka uluvo lwakho apha okokuqala.
Faka uluvo lwakho