Xa ugqirha wakho ekuxelela okanye umntu omthandayo ukuba kufuneka ufumane inaliti ebizwa ngokuba yiBlinatumomab ukuze unyange i-leukemia, kuyinto eqhelekileyo ukuziva usoyika kancinci, unexhala, kwaye unomdla. Loluphi uhlobo lonyango olu? Lulwa njani nomhlaza? Yintoni ekufuneka siyazi? Ndibhala le nkcazo ukuze ndiphendule imibuzo emininzi efana nale onokuba unayo engqondweni yakho. Masithethe ngezi zinto nganye nganye.
Kalula nje, yintoni iBlinatumomab?
I-Blinatumomab (uza kuyifumana rhoqo phantsi kwegama lophawu lwe-BLINCYTO) liyeza elikhethekileyo elisetyenziselwa ukunyanga i-leukemia , uhlobo lomhlaza wegazi. Alifani neyeza eliqhelekileyo le-chemotherapy. Liyeza eliphucukileyo kakhulu.
Ngamafutshane, eli yeza lisebenza ngokuthetha nenkqubo yomzimba wakho yokuzikhusela , ukuyivusa, nokuyinceda ifumane kwaye itshabalalise iiseli zomhlaza. Kufana nokubonisa ukhuselo lomzimba wethu iintshaba ezifihlakeleyo (iiseli zomhlaza) size sizixelele ukuba, "Nanku, zihlasele." Kwizonyango, ezi ntlobo zamayeza sizibiza ngokuba zii-monoclonal antibodies . Oko kukuthi, iproteni eyenzelwe ukuhlasela kuphela injongo ethile.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale unyango
Ukuze ufumane unyango olungcono nolukhuselekileyo, kubalulekile ukuba ugqirha wakho ayazi imbali yakho epheleleyo yempilo. Ngoko ke, ukuba kukho nayiphi na kwezi zilandelayo ezikukhathazayo, qiniseka ukuba uxelela ugqirha wakho ngaphandle kokuzibamba .
- Ukuba ukhe wanyangwa ngemitha engqondweni: Ukuba ukhe wanyangwa ngemitha kwindawo ethile yengqondo yakho ngaphambili, qiniseka ukuba uyayikhankanya loo nto.
- Usulelo lwangoku: Ukuba okwangoku unayo nayiphi na intsholongwane , efana nomkhuhlane, ukukhwehlela, umkhuhlane, okanye usulelo lomchamo.
- Isifo sesibindi: Ukuba unesifo esinxulumene nesibindi.
- Iingxaki zenkqubo yemithambo-luvo: Ukuba ukhe waxhuzula ngaphambili, ukuba uziva ngathi ulahlekelwa yinkumbulo, ukuba uneengxaki ezifana nobunzima bokuthetha, okanye ukuba ulahlekelwa yibhalansi yakho xa uhamba.
- Ukuba ucwangciselwe ukufumana ugonyo: Ukuba uceba ukufumana naluphi na ugonyo kungekudala.
- Ii-Allergy: Ukuba une-allergy kule Blinatumomab okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukuba uzama ukukhulelwa okanye ukhulelwe: Oku kubaluleke kakhulu ukuba ukhulelwe okanye uceba ukuba nomntwana. Eli yeza linokubangela ingozi enkulu kumntwana ngexesha lokukhulelwa.
- Ukuba uncancisa:Ukuba ungumama oncancisa umntwana.
Ndingakunika njani eli yeza?
Le ayisiyo pilisi oyiginyayo. I-Blinatumomab liyeza elifakwa emthanjeni . Lidla ngokunikwa esibhedlele okanye eklinikhi, phantsi kweliso elibukhali labasebenzi bezonyango.
Oku akuqhelekanga ukuba kwenziwe kube kanye. Kunikwa kwingxowa encinci (ingxowa yokufaka) kwaye kunikwa njengesicombululo setyuwa esifakwa kancinci emzimbeni wakho kangangeeyure ezingama-24. Ngale ndlela, unyango lunokuqhubeka iintsuku ezininzi.
Ngaphambi kokuba uqale unyango ngalunye, uza kunikwa incwadana yolwazi ekhethekileyo (iMedGuide) malunga nalo mayeza. Kubaluleke kakhulu ukulifunda nokuliqonda ngononophelo ngalo lonke ixesha.
Kwanabantwana abancinci (ukususela kwinyanga enye ubudala) banikwa eli yeza kwiimeko ezithile ezikhethekileyo. Nangona kunjalo, isigqibo senziwa ngugqirha wezingane.
Kuthekani ukuba ngempazamo usele amayeza amaninzi kakhulu?
Oku kunikwa esibhedlele, ngoko ke amathuba okuba oku kwenzeke mancinci kakhulu. Nangona kunjalo, ukuba ucinga ukuba usenokuba uthathe amayeza amaninzi kakhulu, fowunela iZiko loLwazi lweeTyhefu zeSizwe kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko . Okanye, yiya kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Kuthekani ukuba ndiphoswa yiseshoni yonyango?
Kubaluleke kakhulu ukugqiba umjikelo wakho wonyango ngokuchanekileyo. Ungaphoswa ziiseshoni zonyango nangasiphi na isizathu. Ukuba ngesizathu esithile awukwazi ukuza esibhedlele ngosuku olucwangcisiweyo, fowunela iqela lakho lezonyango ngoko nangoko uze ubazise.
Amanye amayeza anokusebenza kunye nale mayeza
Kubalulekile ukuxelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo (kuquka iivithamini kunye namayeza esintu), njengoko amanye amayeza enokuchaphazela i-Blinatumomab.
| Amayeza/izinto ezinokuba yingxaki | Ingcaciso elula |
|---|---|
| Izitofu zokugonya iintsholongwane eziphilayo | Kuphephe ukufumana imijovo yentsholongwane ephilayo (umz. imasisi, i-mumps) ngelixa usela eli yeza. Eli yeza litshintsha amasosha omzimba wakho, ngoko ke unokufumana usulelo kwezi mijovo. |
| I-Cyclosporine | La mayeza akwathintela amajoni omzimba. Kufuneka iingcebiso zonyango ngaphambi kokuba uwasebenzise kunye. |
| I-Warfarin | Ukuba usebenzisa eli yeza elithintela ukujiya kwegazi, ukusebenza kwalo kunokutshintsha xa usebenzisa iBlinatumomab. |
Olu luhlu aluphelelanga, ngoko ke xelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo.
Izinto ekufuneka uzilumkele ngakumbi ngexesha lonyango
Iqela lakho lezonyango liza kukujonga ngokusondeleyo ngelixa usenza olu nyango, kodwa kubalulekile nokuba ukhathalele umzimba wakho.
Lumka malunga nosulelo.
Eli yeza linokuchaphazela ukusebenza kwenkqubo yakho yokuzikhusela komzimba, nto leyo enokunyusa umngcipheko wokufumana usulelo. Ke ngoko, ukuba ubonakalisa iimpawu zomkhuhlane ezifana nomkhuhlane, ukugodola, umphimbo obuhlungu, kunye nokukhwehlela , musa ukuzenza unyango kwaye wazise iqela lakho lezonyango ngoko nangoko. Nciphisa ukutyelela kwakho kwiindawo apho abantu bagula khona.
Uvavanyo lwegazi
Ngexesha lonyango, kuya kufuneka ukuba uhlolwe igazi rhoqo (umsebenzi wegazi) ukujonga amanqanaba egazi lakho.
Ukuqhuba nokusebenzisa oomatshini
Eli yeza linokuchaphazela ulungelelwano lwakho, ixesha lokuphendula, kunye nokukwazi kwakho ukwenza izigqibo . Ngoko ke, kuphephe ukuqhuba okanye ukusebenzisa oomatshini abanzima ude wazi kakuhle ukuba eli yeza likuchaphazela njani. Ukunciphisa umngcipheko wokuba nesiyezi okanye ukuba nentloko ebuhlungu, yima ngokukhawuleza, nokuba uhleli okanye ulele phantsi. Ukusela utywala kunokwenza ezi ziphumo zibe zimbi ngakumbi.
Ukukhulelwa nokuncancisa (kubaluleke kakhulu)
Kufuneka ulumke kakhulu ngale nto. Ukukhulelwa ngelixa usela eli yeza kwaye emva kweeyure ezingama-48 emva komthamo wokugqibela kunokubangela iziphene ezinkulu zokuzalwa komntwana.
- Ngaphambi kokuba uqale unyango, uza kuvavanywa ukuqinisekisa ukuba awukhulelwanga.
- Kubalulekile ukusebenzisa uhlobo lokuthintela ukukhulelwa oluthembekileyo kulo lonke ixesha lonyango nakwiiyure ezingama-48 emva konyango. Thetha nogqirha wakho ngale nto uze ukhethe eyona ndlela ifanelekileyo.
- Kuphephe ukuncancisa ngokupheleleyo xa usebenzisa eli yeza kwaye kangangeeyure ezingama-48 emva kwedosi yokugqibela.
Zeziphi iziphumo ebezingalindelekanga endinokuzifumana?
Njengalo naliphi na iyeza elinamandla, iBlinatumomab inokubangela iziphumo ebezingalindelekanga. Ezinye zinzima kwaye kufuneka zixelwe ngoko nangoko. Ezinye zihlala zingenzima, kodwa ukuba ziyaqhubeka, kufuneka uxelele ugqirha wakho .
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka uzixele kugqirha wakho ngoko nangoko | |
|---|---|
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi okanye umqala. |
| I-Cytokine Release Syndrome | Umkhuhlane, ukubanda, ukudinwa kakhulu, ukungabi namdla wokutya, isicaphucaphu, intloko ebuhlungu, isiyezi, ukuquleka, ubunzima bokuphefumla, ukubetha kwentliziyo okukhawulezayo okanye okungahambelaniyo. Oku kusenokuba yindlela enamandla yokusabela kwiyeza. |
| Usulelo | Umkhuhlane, ukubanda, ukukhohlela, umphimbo obuhlungu, amanxeba angapholiyo, usulelo lomchamo, kunye neentlungu zomzimba. |
| Ukulimala kwesibindi | Intlungu kwicala eliphezulu lasekunene lesisu, ukuphelelwa ngumdla wokutya, isicaphucaphu, indle ekhanyayo, umchamo otyheli okanye omdaka omnyama, ukutyheli kolusu okanye amehlo, kunye nokudinwa kakhulu. |
| Iingxaki zenkqubo yemithambo-luvo | Intlungu emilenzeni, ukungaziva, ubuthathaka, utshintsho ekuboneni, ukudideka, ubunzima bokuthetha, ukulahleka kokulinganisela, ubunzima bokuhamba, ukuxhuzula. |
| I-Pancreatitis | Intlungu ebuhlungu esiswini esingaphezulu, ephuma emqolo. Intlungu eba mandundu xa usitya okanye uchukumisa isisu, umkhuhlane, isicaphucaphu, ukuhlanza. |
| Isifo seTumor Lysis (TLS) | Imeko ebangelwa kukutshatyalaliswa ngokukhawuleza kweeseli zomhlaza. Isicaphucaphu, ukuhlanza, urhudo, ukuncipha kokuphuma komchamo, umchamo omnyama, ukudinwa kakhulu, ukudideka, ukuxhuzula kwemisipha, iintlungu zamalungu, kunye notshintsho kwisantya sentliziyo. |
| Iziphumo ebezingalindelekanga ezingaqhelekanga, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Intloko ebuhlungu | Intloko ebuhlungu ngokubanzi inokubakho. |
| Ukudumba komzimba | Ukudumba kwamaqatha, izandla, okanye iinyawo. |
| Iingxolo | Ukungcangcazela okungalawulekiyo kwamalungu omzimba, njengezandla neenyawo. |
Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga. Ukuba ufumana into engaqhelekanga okanye engathandekiyo, thetha nogqirha wakho ngayo.
Umyalezo Wokuya Ekhaya
- I-Blinatumomab liyeza eliphucukileyo kakhulu elivuselela amajoni akho omzimba ukuba alwe ne-leukemia.
- Ngaphambi kokuba uqale unyango, xelela ugqirha wakho lonke ulwazi lwakho lwempilo, amayeza owasebenzisayo, kunye nazo naziphi na izinto ezibangela ukuba ungabi namdla.
- Ngexesha lonyango, lumka kakhulu xa ubona iimpawu zosulelo ezifana nomkhuhlane nokukhwehlela, kunye neempawu ezingaqhelekanga ezinxulumene nenkqubo yemithambo-luvo (ubunzima bokuthetha, ukuxhuzula). Ukuba ubona nantoni na, xelela ugqirha wakho ngoko nangoko.
- Kubaluleke kakhulu:Kuphephe ukukhulelwa ngokupheleleyo ngexesha lonyango kwaye emva kweeyure ezingama-48 emva konyango. Qiniseka ukuba usebenzisa iindlela zokulawula ukukhulelwa ezithembekileyo. Kwakhona kuphephe ukuncancisa ngeli xesha.
- Olu asilulo uhambo oluhamba wedwa. Thetha ngokukhululekileyo nogqirha wakho kunye neqela lezonyango malunga nemibuzo okanye iinkxalabo onokuba nazo.
💬 Comments (0)
Akukho zimvo zithunyelweyo okwangoku. Faka uluvo lwakho apha okokuqala.
Faka uluvo lwakho