Kunzima ukuchaza ngamazwi ukuba kunjani ukufunyanwa unomhlaza. Nangona kunjalo, ngokuhambela phambili kwesayensi yezonyango, kukho unyango oluninzi oluphambili olufumanekayo namhlanje lokulwa nomhlaza. Namhlanje siza kuthetha ngonyango olutsha nolukhethekileyo. Le yindlela entle esebenzisa iiseli zakho ukutshabalalisa iiseli zomhlaza.
Yintoni le Brexucabtagene Autoleucel?
Eli gama lisenokuvakala liyinkimbinkimbi kancinci, kodwa ukuyibeka ngokulula, eli liyeza elikhethekileyo elisetyenziselwa ukunyanga iintlobo zomhlaza ezifana ne-leukemia kunye ne-lymphoma . Kodwa eli asilo pilisi esidla ngokuyithatha okanye inaliti esiyinikwayo. Oku kwahlukile kakhulu koko.
Khawucinge nje, sinomkhosi wokhuselo emizimbeni yethu. Siwubiza ngokuba yinkqubo yokuzikhusela . Amajoni (iiseli zokuzikhusela) kulo mkhosi ngawo alwa neentsholongwane ezibangela izifo. Kolu nyango, uthatha amanye ala majoni okhuselo (iiseli) emzimbeni wakho, uwanike uqeqesho olukhethekileyo, uwafundise ukuqaphela nokuhlasela iiseli zomhlaza, uze uwabuyisele emzimbeni wakho. Kwizonyango, oku kubizwa ngokuba yi -CAR T-cell therapy . Oko kukuthi, olu nyango lusebenzisa inkqubo yakho yokuzikhusela ukunceda ekumiseni okanye ekunciphiseni ukusasazeka kweeseli zomhlaza.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale unyango
Ekubeni olu nyango lukhethekileyo, kubalulekile ukuba ugqirha wakho azi imeko yakho yonke yempilo ngaphambi kokuba uluqale. Ke ngoko, ukuba unenye yezi meko zilandelayo, qiniseka ukuba uxelela ugqirha wakho ngazo.
- Isifo sentliziyo: Ukuba unesifo sentliziyo.
- Usulelo: Naziphi na iimeko zosulelo ezikhoyo ngoku.
- Izifo zokudumba: Malunga neemeko zokudumba emzimbeni.
- Isifo sezintso okanye sesibindi: Ukuba kukho ingxaki ngezintso okanye isibindi.
- Isifo semiphunga okanye sokuphefumla: Ubunzima bokuphefumla obufana ne-asthma okanye i-COPD.
- Iingxaki zenkqubo yemithambo-luvo: Ukuba ukhe waxhuzula ngaphambili, ukuba ukhe wahlaselwa sistroke, okanye ukuba unengxaki yokukhumbula.
- Ukugonywa: Ukuba usandul’ ukufumana naluphi na ugonyo, okanye uceba ukuzifumana kwixesha elizayo.
- Ii-Allergies: Ukuba une-allergy kule yeza okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukukhulelwa: Ukuba ukhulelwe, okanye uzama ukukhulelwa.
- Ukuba ungumama oncancisayo: Ukuba uncancisa umntwana wakho.
Olu lwazi luya kunceda kakhulu ugqirha wakho ukuba agqibe ukuba unyango lufanelekile kwaye lukhuselekile kangakanani kuwe.
Lunikwa njani olu nyango?
Oku akuyonto inokwenziwa ekhaya. Lonke eli xesha lenzeka esibhedlele okanye ekliniki, phantsi kweliso elibukhali leqela lezonyango.
Ngamafutshane, oku kwenzeka ngamanyathelo ambalwa:
1. Ukuqokelelwa kweeseli: Okokuqala, igazi lithathwa kumthambo osengalweni yakho, liqhagamshelwe kumatshini okhethekileyo, kwaye iiseli zomzimba (ii-T-cells) zahlulwe egazini lakho. Oku kungathatha iiveki ezininzi.
2. Ukuguqulwa kweeseli: Emva koko, iiseli zakho zomzimba ezizimeleyo zithunyelwa kwilabhoratri ekhethekileyo, apho ziguqulwa khona ngokwemfuza kwaye "ziqeqeshwe" ukuqaphela nokuhlasela iiseli zomhlaza.
3. Ukulungiselela: Kwiintsuku ezimbalwa ngaphambi kokuba ezi seli ziqeqeshweyo zibuyiselwe emzimbeni wakho, uza kunikwa i-chemotherapy enesilinganiselo esiphantsi. Ungakhathazeki, oku kuya kunceda ukunciphisa inani lezinye iiseli zomzimba emzimbeni wakho kwaye kudalwe imeko-bume yokuba iiseli ezintsha eziqeqeshweyo zisebenze kakuhle.
4. Ukufakwa kwakhona kweeseli: Okokugqibela, iiseli eziqeqeshwe kwilebhu ziphinda zifakwe emzimbeni wakho ngemithambo (infusion) efana ne-saline.
Ngaphambi kokuba unyango lwakho luqale, uza kunikwa incwadana yolwazi ekhethekileyo (`MedGuide`). Kubaluleke kakhulu ukuyifunda nokuyiqonda ngononophelo.
Eyona nto ibalulekileyo kukuba, olu nyango lolwakho wedwa. Alunakwabelwana ngalo nomnye umntu. Kuba lwenziwe ngeeseli zakho.
Izinto ekufuneka ziqwalaselwe ngexesha nasemva konyango
Emva konyango, imeko yakho iya kuhlolwa ngononophelo liqela lezonyango.
- Ukujongwa esibhedlele: Emva kokuba iiseli zifakwe emzimbeni wakho, uza kugcinwa ujongiwe ngononophelo ngoogqirha besibhedlele ubuncinane iintsuku ezisi-7 .
- Kuphephe ukuqhuba: Olu nyango lunokuchaphazela ingqalelo yakho, amandla okwenza izigqibo, kunye nokulinganisela. Ngoko ke, kuphephe ukuqhuba okanye ukusebenzisa oomatshini de wazi kakuhle ukuba eli yeza likuchaphazela njani. Yima uhlale phantsi rhoqo ukuze unciphise isiyezi kunye nokungabi nangqondo.
- Ikhadi leWallet yesigulana: Uza kunikwa ikhadi elikhethekileyo. Kuyimfuneko ukuba uligcine nawe ngamaxesha onke. Bonisa eli khadi xa ubona ugqirha. Liqulathe iinkcukacha malunga neempawu zeziphumo ebezingalindelekanga ezinokubakho ngenxa yolu nyango.
- Zikhusele kwiintsholongwane:Olu nyango lunokwenza buthathaka amasosha omzimba wakho, nto leyo eyonyusa umngcipheko wokufumana usulelo. Ukuba ubonakalisa iimpawu ezifana nomkhuhlane, ukubanda, umphimbo obuhlungu, okanye impumlo egobhozayo, musa ukuzinyanga kwaye utsalele umnxeba iqela lakho lezempilo ngokukhawuleza ukuze ufumane iingcebiso. Nciphisa ukudibana kwakho nabantu abagulayo.
- Kuphephe ukunikela ngegazi kunye nezitho zomzimba: Oku kubaluleke kakhulu. Emva kokufumana olu nyango, akufanele unikele ngegazi, izitho zomzimba, izicubu zomzimba, okanye iiseli ubomi bakho bonke.
- Umngcipheko wezinye iintlobo zomhlaza: Ukusebenzisa olu nyango kunokunyusa kancinci umngcipheko wakho wokuba nezinye iintlobo zomhlaza kwixesha elizayo. Thetha nogqirha wakho ngale nto.
Zithini iziphumo ebezingalindelekanga ezinokubakho?
Njengakwezinye iindlela zonyango, kukho iziphumo ebezingalindelekanga. Ezinye zazo zinokuba yingozi, ngoko ke kubalulekile ukuba uzazi.
| Imiphumela | Inkcazo |
|---|---|
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka zixelwe kwiqela lakho lezonyango ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi okanye umqala. |
| I-Cytokine Release Syndrome | Le yindlela ebangela ukusabela okukhulu kwenkqubo yomzimba yokuzikhusela. Iimpawu ziquka umkhuhlane, ukubanda, ukudinwa kakhulu, ukungabi namdla wokutya, isicaphucaphu, intloko ebuhlungu, isiyezi, ukuquleka, ubunzima bokuphefumla, kunye nokubetha kwentliziyo okukhawulezayo okanye okungahambelaniyo. |
| Iingxaki zenkqubo yemithambo-luvo | Umkhuhlane, ukudumba kwee-lymph nodes, ukudideka, ubunzima bokuhamba, ukulahleka kokulinganisela, ukuxhuzula, ubunzima bokuthetha. |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, ukukhohlela, umphimbo obuhlungu, amanxeba angapholiyo, iintlungu xa uchama, kunye nokungonwabi komzimba. |
| Ukuncipha kweeseli zegazi | Ukuncipha kweeseli ezibomvu zegazi kunokubangela ukudinwa okungaqhelekanga, isiyezi, iintloko ezibuhlungu, kunye nobunzima bokuphefumla. |
| Ukopha okungaqhelekanga | Imivumbo emzimbeni wonke okanye ukopha okungayekiyo nokuba yingozi encinci. |
| Iziphumo ebezingalindelekanga ezihlala zingeyongozi, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Iziphumo ebezingalindelekanga ezincinci | Urhudo, ukudinwa, intloko ebuhlungu, ukungabi namdla wokutya, iintlungu zemisipha, isicaphucaphu, ukudumba kwamaqatha, izandla okanye iinyawo. |
Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga. Ukuba ubona into engaqhelekanga, ungathandabuzi ukubuza ugqirha wakho ngayo.
Ngaba kukho iingxaki ngamanye amayeza?
Ewe. Ngokukodwa, musa ukufumana olu nyango ngee -vaccine ze-live virus . Kwakhona, nika ugqirha wakho uluhlu olupheleleyo lwamayeza owasebenzisayo (kuquka iivithamini, amayeza e-herbal, kunye nezongezo) . Kwakhona xelela ugqirha wakho ukuba utshaya okanye usela utywala.
Ekubeni olu lunyango oluqhutywa esibhedlele, akukho thuba lokuba udlule kwi-overdose. Nangona kunjalo, ukuba ufumana naziphi na iimpawu ezingaqhelekanga okanye ezinzima, yiya kwiYunithi yoNyango oluNgxamisekileyo (ETU) ngoko nangoko. Ukuba kuyimfuneko, ungatsalela umnxeba iZiko loLwazi lweePoisons kwiSibhedlele sikaZwelonke saseColombo .
Umyalezo Wokuya Ekhaya
- I-Brexecabtagene Autolucell lunyango oluphucukileyo nolwenzelwe wena olusebenzisa iiseli zakho zomzimba ukulwa nomhlaza.
- Ngaphambi kokuba uqale unyango, xelela ugqirha wakho ngazo zonke iimeko zakho zempilo kunye namayeza owasebenzisayo.
- Olu nyango lunikwa esibhedlele, kwaye uza kugcinwa phantsi kweliso elibukhali lezonyango kangangeentsuku ezimbalwa emva koko.
- Soloko ugcina ikhadi elikhethekileyo (iKhadi leWallet yeSigulana) elinikiweyo kuwe.
- Lumka xa kukho iimpawu ezinobungozi ezifana nomkhuhlane ophezulu, ukudideka, kunye nobunzima bokuphefumla. Ukuba uneengxaki, xelela ugqirha wakho ngoko nangoko.
- Emva kokufumana olu nyango, uya kucetyiswa ukuba unganikeli ngegazi, amalungu omzimba, okanye izicubu ubomi bakho bonke.
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