Ngaba wakha waziva ngequbuliso uziva uxinene esifubeni sakho, nto leyo eyenza kube nzima ukuphefumla? Akukho mazwi okuchaza uloyiko noloyiko olufika engqondweni yakho ngexesha elinjalo, akunjalo? Usenokuba ucinga, "Owu Thixo wam, ngaba esi sisifo sentliziyo?" Ngexesha elinje, namhlanje siza kuthetha ngovavanyo olubaluleke kakhulu oluza kwenziwa ngugqirha ukuze afumanise ukuba kukho into engalunganga ngentliziyo yakho. Oku kubizwa ngokuba luvavanyo lwee-enzymes zentliziyo.
Zithini ezi enzymes zentliziyo? Ngamafutshane...
Kulungile, masiqale sijonge ukuba zeziphi ezi enzymes zentliziyo, okanye ii-biomarkers zentliziyo . Khawuthelekelele intliziyo yakho ingumatshini omangalisayo osebenza ngokungayekiyo. Ukuba le ntliziyo yonakele nangayiphi na indlela, umzekelo, ukuba akukho oxygen yaneleyo, okanye ukuba kukho uxinzelelo olukhulu, izinto ezikhethekileyo ezivela kwiiseli zentliziyo ziyakhutshwa ziye egazini. Ezo zinto zezo sizibiza ngokuba zii-enzymes zentliziyo.
Iienzymes ziiproteni ezikhethekileyo emizimbeni yethu. Ezi zezona zinceda ekulawuleni iinkqubo ezininzi zeekhemikhali zomzimba, ezinje ngokugaya ukutya esikutyayo, ukwenza amandla, kunye nokususa inkunkuma emzimbeni. Ngoko ke, ukuba ezi enzymes zentliziyo zininzi egazini, luphawu lokuba kukho into engalunganga entliziyweni.
Kutheni ezi enzymes zentliziyo zibonakala ngequbuliso egazini?
Ngokwesiqhelo, igazi lomntu ophilileyo liqulathe ubungakanani obuncinci kakhulu bezi enzymes zentliziyo. Kodwa ukuba izihlunu zentliziyo, okanye izihlunu zentliziyo, zonakele nangayiphi na indlela, ezi seli zentliziyo ziyaqhekeka kwaye ii enzymes ezingaphakathi kuzo ziyakhutshwa egazini. Kufana nebhotile yamanzi eqhumayo aze amanzi aphume.
Eyona sizathu siphambili soku kukuhlaselwa yintliziyo . Kwisifo sentliziyo, umthambo ohambisa igazi entliziyweni ngequbuliso uyavaleka, unciphise ioksijini kwinxalenye yentliziyo. Emva koko iiseli zentliziyo eziphulukene neoksijini ziqala ukufa, kwaye le enzyme ikhutshwa egazini.
Ayisiyiyo loo nto kuphela, kodwa nenqanaba lale enzyme egazini linokunyuka nakwiimeko ezifana noxinzelelo lwegazi oluphezulu kunye nokudumba kwentliziyo.
Ngoko ke, yintoni iCardiac Enzyme Marker Test?
Olu luvavanyo lwegazi olulula kakhulu. Ugqirha uthatha inani elincinci legazi lakho aze alivavanye kwilebhu ukuze abone ukuba zingakanani na ezi enzymes zentliziyo, okanye ii-biomarkers zentliziyo, ezikwelo gazi. Ukuba amanqanaba ezi enzymes aphezulu kakhulu kunesiqhelo, ugqirha unokucinga ukuba kukho into engalunganga ngentliziyo yakho okanye ukuba intliziyo yakho isebenza phantsi koxinzelelo olukhulu.
Olu vavanyo lwenziwa njani? Lwenziwa phi?
Olu vavanyo lwegazi aluyonto inkulu. Luthatha nje isampuli encinci yegazi elivela kumthambo osengalweni yakho. Luthatha imizuzu embalwa kuphela.
Kwimeko kaxakeka, oko kukuthi, ukuba ngequbuliso uneentlungu esifubeni uze uye esibhedlele, yiya kwiSebe likaxakeka.Olu vavanyo lwenziwe. Ngaphandle koko, ukuba kufuneka ukwenze oku ngexesha lotyelelo oluqhelekileyo lukagqirha, ungakwenza eofisini kagqirha okanye kwilabhoratri eyahlukileyo yovavanyo lwegazi.
Oogqirha bazisebenzisa njani ezi biomarkers zentliziyo?
La manqanaba eeenzyme zentliziyo abaluleke kakhulu kugqirha. Anga:
- Fumanisa ukuba kukho umonakalo entliziyweni okanye ezinye iingxaki.
- Fumana unobangela ochanekileyo weempawu zakho, ezinje ngeentlungu zesifuba kunye nokuphefumla kancinci. Umzekelo, oku kunokunceda ekuchongeni imeko yentliziyo engalindelekanga ebizwa ngokuba yi -Acute Coronary Syndrome (ACS) , okanye i-Myocardial Ischemia (ukuncipha kokuhamba kwegazi ukuya entliziyweni).
- Jonga ukuba amayeza anikwe isifo sentliziyo asebenza kakuhle na okanye utyando luphumelele.
- Qagela kwangaphambili ukuba kuza kubakho iingxaki ezahlukeneyo zentliziyo.
Khawucinge nje, mhlobo wakho, masithi uKamala. UKamala ngequbuliso uziva exinene esifubeni sakhe, uyabila, kwaye unengxaki yokuphefumla. Xa efika esibhedlele, oogqirha benza uvavanyo lwee-enzymes zentliziyo ngokukhawuleza ngolu hlobo. Yiloo nto ebavumela ukuba babone ukuba kukho into engalunganga ngentliziyo kaKamala, okanye ukuba sisifo sentliziyo. Ukuba nokuxilongwa ngokuchanekileyo kubaluleke kakhulu, kuba kulapho kuphela onokumnika unyango olufanelekileyo.
Ziziphi ezi ntlobo zee-enzymes zentliziyo? (Iintlobo zee-Enzymes zentliziyo)
Kukho iintlobo ezahlukeneyo zee-enzymes zentliziyo. Zonke zii-enzymes okanye iiproteni. Ukuba nezininzi kakhulu egazini lakho kuthetha ukuba usenokuba nesifo sentliziyo okanye enye ingxaki yentliziyo.
Yintoni iTroponin? Le yeyona ibalulekileyo!
Kwezi, i-enzyme ebizwa ngokuba yi -troponin yeyona isetyenziswa ngoogqirha ukubona uhlaselo lwentliziyo okanye umonakalo wentliziyo. Luphawu olunobuthathaka kakhulu. Oku kuthetha ukuba nokuba umonakalo omncinci entliziyweni unokubangela ukuba amanqanaba ayo anyuke egazini.
Cinga ngale nto, emva kokuhlaselwa yintliziyo, inqanaba lale troponin egazini lingaqala ukunyuka kwiiyure ezi-3-4, kwaye lifikelele kwinqanaba eliphezulu kwiiyure ezili-12. Emva koko linokuhlala liphezulu iintsuku ezimbalwa, mhlawumbi neeveki ezimbalwa. Yiyo loo nto ngamanye amaxesha oogqirha bephinda olu vavanyo rhoqo emva kweeyure ezimbalwa okanye emva kweentsuku ezimbalwa. Ngaleyo ndlela banokubona ukuba monakalo mkhulu kangakanani owenzekayo entliziyweni, nokuba iyanda okanye iyancipha.
Masifunde nangeNatriuretic Peptides (NPs)
Olunye uhlobo olukhethekileyo lweproteni lubizwa ngokuba yiNatriuretic Peptides (NPs) . Ezi zinokunyuka egazini.Kwiimeko ezifana nokusilela kwentliziyo. Ukusilela kwentliziyo yimeko apho intliziyo ingakwazi ukupompa igazi elaneleyo emzimbeni. Emva koko kubakho uxinzelelo olukhulu entliziyweni. Ngamaxesha anjalo, inqanaba lezi NPs liyakhula.
Oogqirha bajonga iintlobo ezahlukeneyo zezi NPs, kodwa leyo bayisebenzisa kakhulu ibizwa ngokuba yi -N-terminal proBNP (NT-proBNP) . Oku kungasetyenziselwa ukuvavanya ukuba ingakanani na ingcinezelo ebekwa entliziyweni ngenxa yokungasebenzi kakuhle kwentliziyo.
Ngubani ofuna olu vavanyo lwe-enzyme yentliziyo? Ngaba unazo ezi mpawu?
Ukuba unenye okanye ngaphezulu kwezi mpawu zilandelayo, ugqirha wakho unokuyalela ezi mvavanyo ze-enzyme yentliziyo:
- Intlungu okanye ukungakhululeki esifubeni luphawu oluphambili.
- Ukudinwa, ukuziva ngathi ujikeleza entloko.
- Ukucaphuka, ukuziva ngathi uza kuhlanza.
- Ukubila okukhulu ngequbuliso.
- Ubunzima bokuphefumla, ukuziva ngathi uyafuthaniseka (ukuphelelwa ngumoya).
- Ukwanda ngequbuliso kweempawu zokusilela kwentliziyo (ukwanda kokusilela kwentliziyo), njengokudumba kwemilenze kunye nobunzima bokuphefumla.
Musa ukuthatha nayiphi na kwezi mpawu lula. Ukuba unayo nayiphi na kuzo, kungcono ukufuna ingcebiso kagqirha ngokukhawuleza.
Zeziphi ezinye iimvavanyo zegazi ezenziwayo ukuze kubonwe ukuba kukho uhlaselo lwentliziyo?
Ukongeza kuvavanyo lwee-enzymes zentliziyo, ugqirha unokuyalela nezinye iimvavanyo zegazi ezininzi ukuze afumane umbono ongcono wemeko yentliziyo yakho kunye nempilo iyonke.
Nazi ezinye zazo:
- Ubalo lweGazi olupheleleyo (CBC): Oku kujonga amanqanaba ezinto ezifana neeseli ezibomvu, iiseli ezimhlophe, kunye neeplatelets egazini lakho.
- I-Basic Metabolic Panel (BMP) okanye i-Comprehensive Metabolic Panel (CMP): Oku kunokujonga izinto ezininzi ezifana nee-electrolytes egazini lakho, ezifana ne-sodium kunye ne-potassium, ukusebenza kwezintso, kunye namanqanaba eswekile.
- Uvavanyo lweGesi egazini (ABG): Olu vavanyo lujonga i-oksijini, i-carbon dioxide, kunye nebhalansi ye-asidi egazini.
Ugqirha ufikelela kwisigqibo ngemeko yakho ngokudibanisa ulwazi oluvela kuzo zonke ezi mvavanyo.
Zeziphi ezinye iimvavanyo ezenziwayo ukuze kufunyaniswe isifo sentliziyo?
Ukongeza kuvavanyo lwegazi, kukho ezinye iimvavanyo ezininzi ezinokwenziwa ukuqinisekisa ukuba unesifo sentliziyo okanye omnye umonakalo wentliziyo. Ugqirha wakho unokuyalela enye okanye ezingaphezulu kwezi, kuxhomekeke kwimeko yakho.
- I-X-reyi yesifuba: Oku kunokujonga ubungakanani kunye nokuma kwentliziyo kunye nemeko yemiphunga.
- I-Echocardiogram:Oku kufana ne-ultrasound scan yentliziyo. Ingajonga indlela amagumbi entliziyo kunye neevalvu ezisebenza ngayo, kunye nendlela izihlunu zentliziyo ezincipha ngayo. Ngamanye amaxesha uvavanyo olukhethekileyo lwe-echo olubizwa ngokuba yi-Transesophageal Echocardiogram (TEE) lunokwenziwa.
- I-Electrocardiogram (ECG okanye EKG): Le ilinganisa umsebenzi wombane wentliziyo yakho. Oku kunokuba luncedo kakhulu ekufumaneni iingxaki kwintliziyo yakho, njengeempawu zokuhlaselwa yintliziyo.
- Uvavanyo loxinzelelo lomzimba okanye uvavanyo loxinzelelo lwentliziyo yenyukliya: Oku kuquka ukuhamba nge-treadmill okanye ukukhwela ibhayisekile uze ubone indlela intliziyo yakho esabela ngayo kulo mthambo.
- I-Angiogram: Kolu vavanyo, kufakwa ulwelo olukhethekileyo kwimithambo yentliziyo ethwala igazi ukuya entliziyweni, kwaye kuthathwa i-X-ray ukuze kubonwe ukuba kukho na ukuvaleka kwaloo mithambo.
- I-Positron Emission Tomography (PET) Scan: Le ikwayi-scan ekhethekileyo ejonga ukusebenza kwentliziyo kunye nokuhamba kwegazi.
Zonke ezi mvavanyo zenziwa ukuze kuchongwe ukuba yeyiphi kanye kanye ingxaki onayo kwaye kubonelelwe ngonyango olufanelekileyo ngayo.
Eyona nto ibalulekileyo ekufuneka uyikhumbule: khathalela intliziyo yakho!
"Ingaba ndinesifo sentliziyo?" Lo mbuzo unokuba yingozi kakhulu kwaye woyikise ukucinga ngawo. Ke ngoko, ukuba ufumana naziphi na iimpawu, eyona nto ingcono onokuyenza kukufuna ingcebiso kagqirha ngokukhawuleza, ngaphandle kokuyicinga kakhulu.
Njengoko mhlawumbi uyaqonda, olu vavanyo lwee-enzyme zentliziyo lubaluleke kakhulu ekuxilongeni isifo sentliziyo, ingakumbi iziganeko zentliziyo ezikhawulezileyo. Ukuba namanqanaba aphezulu ezi enzymes egazini lakho luphawu oluqinileyo lokuba kukho umonakalo othile, uxinzelelo, okanye ukudumba entliziyweni yakho.
Ngoko ke, ukuba ugqirha wakho ukucela ukuba wenze olu vavanyo, ungoyiki. Luza kukunceda wazi kakuhle imeko yakho kwaye uqale unyango olufunekayo ngokukhawuleza. Ukuxilongwa kwangoko kunye nonyango kunokusindisa ubomi bakho kwaye kuthintele iingxaki ezinkulu. Intliziyo yakho yeyona nto ixabisekileyo kuwe. Kuxhomekeke kuwe ukuyinyamekela. Thetha nogqirha wakho kwaye uqonde ukuba ezi ziphumo zovavanyo zithetha ukuthini.
👩🏽⚕️ Imibuzo eyongezelelweyo (Ii-FAQ)
💬 Yintoni uvavanyo lweCardiac Enzymes (Cardiac Enzymes / Troponin)?
Xa uhlaselwa yintliziyo uze uye esibhedlele, olu luvavanyo lwegazi oluyimfuneko nolubaluleke kakhulu oluye lwenziwa ngoogqirha, ukongeza kwi-ECG! Xa izihlunu zentliziyo yethu zitshatyalalisiwe/zibolile, uhlobo lweproteni (iTroponin kunye nezinye ii-enzymes) ngaphakathi kuloo zihlunu lukhutshwa egazini ngobuninzi obunganyamezelekiyo. Lolo luphawu olufunwa lolu vavanyo.
💬 Ngaba le ngxelo iza kuyibona isifo sentliziyo kwangoko nje xa sisenzeka?
Ifunyanwa ngoko nangoko yi-ECG. Ixabiso leTroponin kukuba nokuba ukuhlaselwa yintliziyo 'okungathethiyo' okungabonakaliyo kwi-ECG kunokubonwa yile ngxelo kwiiyure ezi-2 ukuya kwezi-4. Xa oogqirha bethatha igazi baze bajonge la maxabiso (amanqanaba eTroponin), ukuba libonakala 'liphezulu', oko kuthetha ukuba uninzi lwemisipha yentliziyo yakho sele ifile.
💬 Ukuba ii-enzymes ezikule ngxelo ziphezulu, ngaba kuya kufuneka ndenze utyando?
Inqanaba eliphezulu le-troponin lithetha ukuba kukho umonakalo omkhulu entliziyweni (uhlaselo lwentliziyo olucacileyo). Kwakuba nje oku kusenzeka, oogqirha baya kukunika isithambisi segazi okanye isithambisi segazi. Ukuba inqanaba le-enzyme liphezulu kakhulu, kuya kwenziwa i-angiogram ngoko nangoko ukuze kuqinisekiswe ukuba ngaba kufuneka utyando lwe-stent okanye lwe-bypass.
Iienzymes zentliziyo , uhlaselo lwentliziyo, iienzymes zentliziyo, itroponin, iintlungu zesifuba, uhlaselo lwentliziyo, uvavanyo lwegazi, ii-biomarkers zentliziyo
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