Yintoni i-cortisol? Ichaphazela njani umzimba wakho?

Mhlawumbi ukhe weva igama elithi 'cortisol', ingakumbi xa kuthethwa 'ngoxinzelelo'. Kodwa ubusazi na ukuba, asiyo 'hormone yoxinzelelo' nje kuphela? I-Cortisol yihormone ebaluleke kakhulu emizimbeni yethu. Enyanisweni, ichaphazela phantse onke amalungu kunye nezicubu zomzimba wethu.

Yintoni kanye kanye i-cortisol?

Ngamafutshane, i-cortisol yi-hormone eyenziwa kwaye ikhutshwe zii -adrenal glands zakho - ii-glands ezimbini ezincinci ezikwindawo engaphezulu kwezintso zakho. Ikwiqela lee -hormone ezibizwa ngokuba yi-glucocorticoids , ezizi-hormone ze-steroid.

Usenokucinga ukuba oku kubalulekile kuphela kuxinzelelo. Kodwa akunjalo. I-Cortisol ineminye imisebenzi emininzi ebalulekileyo ekufuneka iyenze. Umzekelo:

• Ilawula indlela umzimba wethu osebenzisa ngayo iswekile, okanye iglucose , ukuze ufumane amandla.
• Inciphisa ukudumba emzimbeni.
• Ilawula uxinzelelo lwegazi.
• Inceda ukugcina umjikelo wethu wokulala nokuvuka.

Umzimba wethu uhlala ujonge eli nqanaba le-cortisol, uligcina likwinqanaba elizinzileyo, oko kukuthi, kwimeko ye-homeostasis . Kuba nokuba amanqanaba e-cortisol aphezulu okanye aphantsi, akulunganga kwimpilo yethu.

Ngoko ke ngaba i-cortisol 'yi-hormone yoxinzelelo' ngokwenene?

Ewe, i-cortisol idlala indima ebalulekileyo kwimpendulo yemizimba yethu kuxinzelelo. I-Cortisol ikhutshwa xa ufumana naluphi na uhlobo loxinzelelo, olufana nolu:

• Uxinzelelo oluqatha – Cinga ngayo njengokusukela inja ngequbuliso.
• Uxinzelelo olungapheliyo - umzekelo, iingxaki eziqhubekayo emsebenzini okanye iingxaki zosapho.
• Uxinzelelo olubuhlungu – njengokubona isiganeko esingenakucingelwa.

Kodwa, njengoko benditshilo ngaphambili, i-cortisol inezinto ezininzi ekufuneka zenziwe kunokunceda nje ngoxinzelelo.

I-cortisol iyichaphazela njani umzimba wam?

I-Cortisol ichaphazela phantse zonke iinkqubo zomzimba emzimbeni wethu, kwaye ikwanceda ekulawuleni imisebenzi emininzi ebalulekileyo.

Ukulawula indlela imizimba yethu esabela ngayo kuxinzelelo

Xa sixinezelekile, imizimba yethu iqala ikhuphe iihomoni ezinxulumene nempendulo 'yokulwa okanye yokubaleka' , njenge- adrenaline . Emva koko i-cortisol iyakhutshwa. Uyazi ukuba kutheni? Ukusigcina silindile. I-Cortisol ikwanceda isibindi sethu sikhuphe i-glucose , eyiswekile. Yile nto isinika amandla ngokukhawuleza ngamaxesha oxinzelelo.

I-metabolism kunye nolawulo lweswekile egazini

I-MetabolismNgamafutshane, zonke iinkqubo zeekhemikhali ezisinceda siphile kwaye sisebenze ngaphakathi emizimbeni yethu. Amawaka ezi nkqubo zenzeka emizimbeni yethu ngamaxesha onke.

I-Cortisol ichaphazela le metabolism ngokulawula indlela imizimba yethu esebenzisa ngayo i-glucose ukuze ibe namandla. Ikwenza oku ngeendlela ezahlukeneyo. Umzekelo, i-cortisol ixelela i-pancreas yethu ukuba inciphise ukuveliswa kwe -insulin kwaye inyuse ukuveliswa kwe -glucagon . I-insulin yehlisa iswekile yegazi, kwaye i-glucagon inyusa iswekile yegazi. Uyayazi?

Ayipheleli apho, i-cortisol ikwachaphazela nezinye izicwili ezininzi emzimbeni wethu kwaye ilawula ukusetyenziswa kweglucose.

• Izicubu zamafutha – oko kukuthi, amafutha emzimbeni.
• Isibindi
• Izihlunu

Ukuthintela ukudumba

Ngexesha elifutshane, i-cortisol inokunciphisa ukudumba , okukukudumba nokubomvu emzimbeni, kwaye inyuse amasosha omzimba wethu. Nangona kunjalo, ukuba umzimba wakho unezinga eliphezulu le-cortisol ixesha elide, umzimba wakho uyaziqhelanisa nako. Okunokwenzeka kukuba ukudumba kuyanda kwaye inkqubo yakho yokuzikhusela yomzimba ibuthathaka.

Ukulawula uxinzelelo lwegazi

Akukacaci kakuhle ukuba i-cortisol ilawula njani uxinzelelo lwegazi ebantwini. Nangona kunjalo, ukuba amanqanaba e-cortisol aphezulu kakhulu, inokukhokelela kuxinzelelo lwegazi oluphezulu. Ngokufanayo, ukuba amanqanaba e-cortisol aphantsi kakhulu, inokukhokelela kuxinzelelo lwegazi oluphantsi.

Ukunceda ukulawula umjikelo wokulala nokuvuka

Uninzi lwabantu lunezinga eliphantsi le-cortisol xa besiya kulala ebusuku. Amanqanaba e-cortisol afikelela kwinqanaba eliphezulu ngaphambi kokuba bavuke kusasa. Oku kubonisa ukuba i-cortisol inxulumene kakhulu nesigqi sethu se-circadian , yindlela esebenza ngayo imizimba yethu nendlela esivuka ngayo kuxhomekeke kwixesha losuku.

Umzimba wam ulawula njani amanqanaba e-cortisol?

Imizimba yethu inenkqubo entsonkothileyo kakhulu yokulawula amanqanaba e-cortisol. I-hypothalamus yakho - inxalenye yengqondo yakho - kunye ne-pituitary gland yakho - i-gland encinci ekwisiseko sobuchopho bakho - zisebenza kunye ukulawula ukuveliswa kwe-cortisol yi-adrenal glands yakho. Nantsi indlela esebenza ngayo:

• Xa amanqanaba e-cortisol egazini lakho ehla, i-hypothalamus ikhupha i -hormone ebizwa ngokuba yi-corticotropin-releasing hormone (CRH) .
• Oku kuxelela i-pituitary gland yakho ukuba yenze i-adrenocorticotropic hormone (ACTH) .
• Emva koko i-ACTH iyahamba ize ixelele amadlala akho e-adrenal ukuba enze kwaye akhuphe i-cortisol.

Ngoko ke, ukuze ugcine amanqanaba e-cortisol asempilweni, i-hypothalamus yakho, i-pituitary gland, kunye ne-adrenal glands zonke kufuneka zisebenze ngokufanelekileyo.

Yintoni ebangela amanqanaba aphezulu e-cortisol?

Ukuba unezinga eliphezulu le-cortisol emzimbeni wakho ixesha elide ( i-hypercortisolism ), idla ngokubizwa ngokuba yi-Cushing's syndrome . Izinto ezinokubangela amanqanaba aphezulu e-cortisol kunye ne-Cushing's syndrome ziquka:

• Ukuthatha amayeza e -corticosteroid aphezulu, afana ne -prednisone , i-prednisolone , kunye ne-dexamethasone .
• Iithumba ezivelisa i-ACTH – Ezi zihlala zikhula kwi-pituitary gland yakho.
• Iithumba ezikhula kwi-adrenal glands zize zivelise i-cortisol egqithisileyo.

Zithini iimpawu zamanqanaba aphezulu e-cortisol?

Xa amanqanaba e-cortisol ephakanyisiwe, okuyi- Cushing's syndrome, iimpawu ezifana nezi:

• Ukwanda kobunzima, ingakumbi ebusweni nasesiswini.
• Amafutha ahlala emqolo phakathi kwamagxa (njengenkunzi yenkomo).
• Ukubonakala kweempawu zokunwebeka ezibanzi, ezimfusa esiswini.
• Ubuthathaka bemisipha kwiingalo nasemathangeni angaphezulu.
• Ukwanda kwamanqanaba eswekile egazini kudla ngokukhokelela kwi- Type 2 Diabetes Mellitus .
• Igazi elonyukayo.
• Kwabasetyhini, ukukhula kweenwele okungafunekiyo emzimbeni ( i-hirsutism ).
• Ukubuthathaka kwamathambo ( i-osteoporosis ) kunye nokuqhekeka kwamathambo kunokwenzeka.

Khangela, ungoyiki kuba nje unempawu enye okanye ezimbini kwezi. Kodwa ukuba uziva ngathi unezinye zezi zinto, kungcono ukubona ugqirha.

Yintoni ebangela amanqanaba aphantsi e-cortisol?

Oogqirha bathi kukungasebenzi kakuhle kwe-adrenal, okwenzeka xa amanqanaba e-cortisol ephantsi kunesiqhelo ( i-hypocortisolism ). Kukho iintlobo ezimbini zale nto: eyokuqala neyesibini.

Ukungasebenzi kakuhle kwe-adrenal cortex kudla ngokuvela xa inkqubo yakho yokuzikhusela yomzimba ihlasela amadlala akho e-adrenal. Oku kukwabizwa ngokuba sisifo sika-Addison . I-Cortisol inokuncipha ukuba izicubu zamadlala e-adrenal zisulelekile okanye ukuba ukuhamba kwegazi kuzo kuvaliwe.

Ukungasebenzi kakuhle kwe-adrenal yesibini kwenzeka xa i-pituitary gland yakho ingasebenzi kakuhle ( hypopituitarism).) Ewe, ukuba unethumba le-pituitary. Ezi meko zithintela ukuveliswa kwe -ACTH , nto leyo ethintela ukuveliswa kwe-cortisol. Kwakhona, ukuba usebenzisa amayeza e-corticosteroid uze uyeke ngequbuliso, amanqanaba akho e-cortisol anokwehla.

Zithini iimpawu zamanqanaba aphantsi e-cortisol?

Xa amanqanaba e-cortisol ephantsi, okubangelwa kukungasebenzi kakuhle kwe-adrenal , iimpawu ezifana nezi:

• Ukuhlala uziva udiniwe kwaye udiniwe (Ukudinwa).
• Ukunciphisa umzimba ngengozi.
• Ukulahlekelwa yintliziyo.
• Uxinzelelo lwegazi oluphantsi.

Ndifanele ndimbone nini ugqirha malunga namanqanaba am e-cortisol?

Ukuba uneempawu ezibonisa ukuba une -Cushing's syndrome okanye i-adrenal insufficiency , qiniseka ukuba ubona ugqirha wakho. Musa ukulibazisa.

Kwakhona, ukuba unengxaki yoxinzelelo lwemihla ngemihla, thetha nogqirha wakho malunga neendlela zokulawula olo xinzelelo. Usenokufumana uncedo.

Ndingawanciphisa njani amanqanaba e-cortisol yam?

Ukuba unesifo esifana neCushing's syndrome , kuya kufuneka unyango ukuze wehlise amanqanaba akho e-cortisol. Oku kudla ngokubandakanya amayeza okanye utyando.

Nangona kunjalo, kukho iindlela ezahlukeneyo zokunceda ukulawula amanqanaba ethu e-cortisol ngokubanzi, ingakumbi xa amanqanaba e-cortisol enyuka ngenxa yoxinzelelo:

• Lala kakuhle, uphumle ebusuku. Iingxaki ezifana nokungalali kakuhle kunye nokusebenza ebusuku zinokunyusa amanqanaba e-cortisol. Zama ukulala ubuncinane iiyure ezisi-7-8 ngosuku.
• Shukumisa umzimba wakho kwaye uzilolonge. Ukuzilolonga rhoqo kuphucula ubuthongo kwaye kunciphisa uxinzelelo. Ukuhamba ubuncinane imizuzu engama-30 ngosuku nako kulungile.
• Yenza umthambo wokuphefumla nzulu. Umthambo wokuphefumla olawula ukuphefumla kwakho uvuselela inkqubo yethu ye-parasympathetic nervous system – inkqubo yethu 'yokuphumla nokugaya'. Oku kunceda ekunciphiseni amanqanaba e-cortisol.
• Yonwaba, hleka. Xa uhleka, ii-endorphins , ii-hormones zovuyo, ziyakhutshwa, kwaye amanqanaba e-cortisol ayancitshiswa. Ukuthatha inxaxheba kwimisebenzi eyonwabisayo kukwaphucula impilo-ntle yengqondo.
• Gcina ubudlelwane obuhle nobusempilweni. Ubudlelwane obuhlala bunengxaki nobuxinezelekileyo bunokukhokelela kuxinzelelo. Ke ngoko, kubalulekile ukugcina ubudlelwane obuhle nabahlobo abalungileyo kunye nosapho.

Okokugqibela, umyalezo oya ekhaya:

Xa abantu besiva igama elithi cortisol, bacinga ukuba yinto embi. Kodwa eneneni yi-hormone ebalulekileyo echaphazela iinkalo ezininzi zemizimba yethu.Zininzi iindlela zokunceda ukunciphisa uxinzelelo kunye nokulawula amanqanaba ethu e-cortisol. Nangona kunjalo, ngamanye amaxesha amanqanaba e-cortisol anokuba phezulu okanye aphantsi ngendlela engaqhelekanga, nto leyo esingenakuyilawula.

Ukuba uneempawu zamanqanaba aphezulu okanye aphantsi e-cortisol, kubalulekile ukubona ugqirha. Banokwenza uvavanyo olulula ukuze babone ukuba amadlala akho e-adrenal okanye i-pituitary gland abangela ezi mpawu. Khumbula, okukhona uyifumanisa ngokukhawuleza, kokukhona kulula ukuyinyanga.

Ngoko ke, khathalela umzimba wakho, kwaye ungoyiki ukufuna ingcebiso kagqirha ukuba ubona into engaqhelekanga okanye eyahlukileyo. Hlala usempilweni!

I- Cortisol, uxinzelelo, iihomoni, ii-adrenal glands, i-Cushing's syndrome, isifo sika-Addison