Ezinye izifo, umzekelo, abantu abanezifo ezifana neThalassemia, kufuneka banike igazi rhoqo emzimbeni. Xa sifumana igazi ixesha elide ngolu hlobo, inqanaba lesinyithi emzimbeni wethu linokunyuka ngokungeyomfuneko. Oku sikubiza ngokuba yi-iron overload. Le iron inyukileyo inokufakwa kwizitho ezibalulekileyo ezifana nentliziyo nesibindi kwaye yonakalise. Ngoko ke, iyeza elikhethekileyo elisetyenziswa ngoogqirha ukususa le iron igqithisileyo emzimbeni libizwa ngokuba yiDeferasirox. Makhe sithethe ngale nto namhlanje.
Yintoni iDeferasirox? Yintoni kanye kanye eyenzayo?
Ngamafutshane, eli yeza libizwa ngokuba yiDeferasirox lisebenza njengemagnethi. Linamathela kumasuntswana esinyithi angafunekiyo, agqithisileyo egazini lethu, liwabambe, kwaye liwancede asuswe emzimbeni. Le nkqubo ibizwa ngokuba yiChelation kwisayensi yezonyango. Oku kuthintela umonakalo onokwenziwa yisinyithi esigqithisileyo kwizitho zethu ezibalulekileyo. Eli yeza linokuba phantsi kwamagama eempawu ezifana neJadenu.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza
Ugqirha wakho kufuneka ayazi imbali yakho yonke yempilo ngaphambi kokuba anike eli yeza. Qiniseka ukuba umxelele ngayo nayiphi na kwezi meko zilandelayo, ingakumbi ukuba unazo:
- Ukuba unayo nayiphi na umhlaza.
- Ukuba unengxaki yokubona okanye izifo zamehlo.
- Ukuba unengxaki yokuva.
- Ukuba unesifo sezintso okanye isifo sesibindi.
- Ukuba unemeko ebangela ukwehla kwenani leeseli ezimhlophe zegazi, iiplatelets, okanye iiseli ezibomvu zegazi egazini (ubuninzi begazi).
- Ukuba une-allergy kule Deferasirox okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukuba ukhulelwe, uzama ukukhulelwa, okanye uncancisa.
Iyeza lifanele lisetyenziswe ngendlela eyiyo.
Kubaluleke kakhulu ukulandela imiyalelo echanekileyo yokusebenzisa eli yeza.
- Sela isisu esingenanto: Eli yeza lifanele lisetyenziswe esiswini esingenanto . Oko kukuthi, ubuncinane imizuzu engama-30 ngaphambi kokutya, okanye iiyure ezi-2 emva kokutya.
- Yithathe ngexesha: Thatha idosi emiselweyo ngexesha elimiselwe ngugqirha wakho. Musa ukuyithatha ngaphezu kwenani elimiselweyo lezihlandlo ngemini.
- Musa ukuyeka: Musa ukuyeka ukuthatha eli yeza ngequbuliso ngaphandle kwengcebiso kagqirha wakho.
Xa kunikwa abantwana abancinci
Eli yeza linokunikwa abantwana abangaphezu kweminyaka emi-2 ubudala kwezinye iimeko ezikhethiweyo. Nangona kunjalo, esi sigqibo siya kwenziwa ngugqirha womntwana wakho. Ke ngoko, ukuba unika umntwana eli yeza, landela imiyalelo kagqirha ngokuchanekileyo.
Kuthekani ukuba ndiphoswa lidosi leyeza?
Ukuba uphoswe yidosi, yithathe ngokukhawuleza xa ukhumbula. Nangona kunjalo, ukuba sele kusondele ixesha lomthamo wakho olandelayo, yitsibe idosi oyiphosileyo uze uthathe idosi yakho elandelayo ngexesha elicwangcisiweyo.Ungaze uthathe iidosi ezimbini ngaxeshanye.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Khawucinge ukuba usele amayeza amaninzi kakhulu ngexesha elingafanelekanga. Ukuba oko kuyenzeka, ungoyiki kwaye utsalele umnxeba iZiko loLwazi ngeTyhefu leSizwe kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko . Okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Amanye amayeza anokusebenzisana neDeferasirox
Eli yeza lisenokudibana namanye amayeza, ngoko ke kubaluleke kakhulu ukuxelela ugqirha wakho ngawo onke amanye amayeza owasebenzisayo (kuquka iivithamini kunye namayeza esintu).
| Uhlobo lweyeza | Inkcazo kunye nemizekelo |
|---|---|
| Izinto ekungafanele uzithathe naliphi na eli yeza | |
| Izongezo zesinyithi | Ukusela eli yeza kuya kususa i-iron engaphezulu emzimbeni, ngoko ke ukuthatha iipilisi ze-iron ngaphandle akuyi kunceda. |
| Amanye amayeza e-Hepatitis C | Umzekelo: Dasabuvir, Ombitasvir, Paritaprevir, Ritonavir |
| Amanye amayeza anokubangela ukudibana (xelela ugqirha wakho ukuba uwasebenzisa la mayeza) | |
| Iiantacids | Amayeza e-gastritis aqulethe i-aluminium. |
| Iipilisi zokubulala iintlungu (ii-NSAID) | Umzekelo: Amayeza afana ne-Ibuprofen kunye ne-Naproxen. |
| Iipilisi zokulawula inzala | Eli yeza linokunciphisa ukusebenza kweepilisi zokulawula ukuzalwa. |
| Amanye amayeza | Amanye amayeza amaninzi, afana namayeza okwehlisa i-cholesterol (iCholestyramine, iSimvastatin), amayeza okuxhuzula (iPhenobarbital), amayeza okunciphisa igazi (iWarfarin), iisteroids (iPrednisone), iCyclosporine, iRifampin, njl. |
Nyamekela umzimba wakho ngelixa usebenzisa amayeza.
Kubaluleke kakhulu ukuqaphela utshintsho emzimbeni wakho ngelixa usebenzisa eli yeza.
Iimpendulo Ezinzima Zesikhumba: Eli yeza ngamanye amaxesha linokubangela iimpendulo ezinzulu zesikhumba. Oku kunokwenzeka nakwiiveki emva kokuba uqalile iyeza. Ukuba ufumana irhashalala ebomvu enomkhuhlane, iintlungu zomzimba, ukuba iba mfusa kwaye ibe namadyungudyungu, ukuba ulusu luyaxobuka, okanye ukuba ufumana irhashalala ebomvu enamaqhuqhuva entanyeni okanye emakhwapheni , bona ugqirha ngoko nangoko.
- Uvavanyo lwezonyango: Ugqirha wakho uza kujonga umbono wakho, ukuva kwakho, kunye negazi lakho (ingakumbi ukusebenza kwezintso nesibindi) ngaphambi kokuba uqale ukuthatha eli yeza kwaye ngelixa ulisebenzisa. Musa ukulibaleka eli yeza.
- Ukopha isisu: Ukuba unendle emnyama, ehlala ixesha elide, okanye ukuhlanza okufana nekofu, kunokuba luphawu lokopha ngenxa yesilonda esiswini okanye emathunjini akho. Ukuba oku kuyenzeka, xelela ugqirha ngoko nangoko.
- Ukudinwa: Eli yeza linokwenza abanye abantu babe nesiyezi. Musa ukuqhuba okanye ukusebenzisa oomatshini ude wazi ukuba eli yeza likuchaphazela njani. Lumka xa uvuka okanye uhlala phantsi ngequbuliso.
- Ukuphelelwa ngamanzi emzimbeni ebantwaneni: Ukuba umntwana wakho unikwe eli yeza kwaye unesisu esibuhlungu kakhulu, ukuhlanza, okanye ukubila kakhulu, xelela ugqirha wakho ngoko nangoko. Ukunika eli yeza kunokuba yingozi ukuba umzimba ulahlekelwa ngamanzi amaninzi (ukuphelelwa ngamanzi emzimbeni).
Iziphumo ebezingalindelekanga ezinokwenzeka ngeli yeza
Njengalo naliphi na iyeza, iDeferasirox inokubangela iziphumo ebezingalindelekanga. Ezinye zazo ziyingozi, ngelixa ezinye zixhaphakile.
| Imiphumela | Inkcazo |
|---|---|
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka zixelwe kugqirha ngoko nangoko | |
| Ukwaliwa kakhulu | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi, ubunzima bokuphefumla. |
| Iimpawu zomonakalo wesibindi | Ukutyheli kolusu okanye amehlo, umchamo otyheli/omdaka omnyama, iintlungu kwicala eliphezulu lasekunene lesisu, ukungabi namdla wokutya, ukudinwa kakhulu. |
| Iimpawu zomonakalo wezintso | Ukuphuma komchamo okunciphileyo, ubunzima bokuchama. |
| Utshintsho embonweni okanye ekuveni | Umbono ofipheleyo, ukuva kancinci. |
| Ukopha okungaqhelekanga | Ukudumba okungeyomfuneko kunye nokopha kolusu. |
| Iziphumo eziqhelekileyo ekufuneka zixelwe kugqirha wakho ukuba ziyaqhubeka okanye ziyakhathaza: | |
| Iingxaki zenkqubo yokugaya ukutya | Intlungu yesisu, urhudo, isicaphucaphu, ukuhlanza. |
| Ukungalali | Ubunzima bokulala. |
Umyalezo Wokuya Ekhaya
- I-Deferasirox liyeza elinikwa ukususa i-iron engaphezulu emzimbeni. Lifanele lithathwe kanye njengoko ugqirha eliyalele, esiswini esingenanto.
- Xelela ugqirha wakho ngazo zonke ezinye iiyeza ozisebenzisayo, ingakumbi iipilisi zokuthomalalisa iintlungu kunye neepilisi zokuthomalalisa iintlungu, njengoko eli yeza lisenokudibana nezinye iiyeza.
- Ukuba ufumana iimpawu ezinzulu ezifana nokurhawuzelela kwesikhumba, isitulo esimnyama, okanye ukutyheli kwamehlo, bonana nogqirha ngokukhawuleza.
- Ngelixa usela eli yeza, qiniseka ukuba ugqirha wakho unika uvavanyo lwegazi, amehlo, kunye nendlebe.
- Eli yeza lelakho wedwa. Ungaze wabelane ngalo nabanye.
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