Ngaba uziva ukudumba, ukuqina, kunye nentlungu phantsi kolusu lwakho? Masithethe nge-Eosinophilic Fasciitis!

Ngaba wakha waziva ngequbuliso iqhuma, ukudumba, okanye intlungu phantsi kwesikhumba sengalo okanye umlenze wakho? Mhlawumbi kwenzeke emva kokuzilolonga kakuhle. Ngaba wakha wahlangabezana nento efana nale? Ngoko ke, nantsi imeko engaziwayo kakhulu enokuba ibalulekile kuwe.

Yintoni i-Eosinophilic Fasciitis?

Ngamafutshane, i-Eosinophilic Fasciitis yimeko apho izicubu ezigubungela izihlunu zethu kunye nezicubu phantsi kolusu lwethu - esizibiza ngokuba yi-fascia ngokwezonyango - zivuvukala ngequbuliso, zijiye, kwaye ziqine. Cinga ngayo njenge-mesh ebamba ulusu kunye nemisipha yethu kunye kwaye izincede zihambe, njenge-mesh esiyibeka kwi-trunk yemoto yethu xa sisiya kuthenga.

Oku kuchazwa njengesifo esizikhusela ngokwazo . Oku kuthetha ukuba inkqubo yokuzikhusela yomzimba wethu, inkqubo yokuzikhusela komzimba, ngempazamo iqala ukuhlasela amalungu omzimba wethu asempilweni. Kufana nokuhlasela amalungu osapho lwethu xa ecinga ukuba aphangiwe.

Ukuba ayifunyaniswanga kwaye inyangwe kwangethuba, inokubangela utshintsho oluhlala luhleli kulusu kunye nokulahleka kokuhamba kwamalungu . Ke ngoko, kubaluleke kakhulu ukufuna ingcebiso kagqirha ngokukhawuleza xa kuvela iimpawu.

Le meko ichaphazela njani kakhulu? Ichaphazela bani?

I-Eosinophilic Fasciitis inokuchaphazela i-fascia naphi na emzimbeni, kodwa idla ngokuchaphazela izandla neenyawo . Kubantu abaninzi, iimpawu, ezinje ngentlungu okanye ukudumba, zinokuqala ukubonakala emva kokuzilolonga okunzima okanye umsebenzi ofuna ukuma imini yonke.

Ezi mpawu, ezinje ngeentlungu zemisipha kunye nokudumba, zinokufana nezezinye izifo eziqhelekileyo, ngoko ke kubalulekile ukubona ugqirha ngoko nangoko ukuba ubona naluphi na utshintsho olutsha okanye intlungu eluswini lwakho, kwimisipha, okanye kumalungu. Kusenokufuneka ubonane nogqirha wamathambo, ugqirha ogxile kumalungu nezinye izifo zokudumba.

Okwangoku akukho nyango lwesi sifo. Nangona kunjalo, iindaba ezimnandi zezokuba kubantu abaninzi, iimpawu ziyaphela kwiminyaka embalwa, oko kuthetha ukuba isifo siya 'kuxolelwa', okanye silale. Nangona kunjalo, abanye abantu banokuphinda babonakale benazo iimpawu.

Umahluko phakathi kwe-Eosinophilic Fasciitis kunye ne-Scleroderma

Xa bethetha ngezi zifo zimbini, abanye abantu banokuzibhidanisa nesinye isifo esibizwa ngokuba yi-'Scleroderma'. I-'Eosinophilic Fasciitis' kunye ne-'Scleroderma' zombini zizifo ezingaqhelekanga kakhulu ze-'autoimmune'. Kwakhona, kuzo zombini ezi zifo, izicubu zomzimba ziyaqina kwaye ziqine.

Ngoko ke yintoni umahluko? Umahluko ukho kwiintlobo zezicubu ezichaphazelekileyo.

• Kwi-Eosinophilic Fasciitis, njengoko besitshilo ngaphambili, i-fascia, isicwili esincinci nesithambileyo esingaphantsi kolusu, siyachaphazeleka. Ekuhambeni kwexesha, le fascia iyanda kwaye iyanda, nto leyo eyenza kube nzima ukuhambisa inxalenye yomzimba echaphazelekayo.
• Kodwa kwi-'Scleroderma', inkqubo yomzimba yokuzikhusela ivuselela ezinye iiseli ukuba zivelise iproteni ebizwa ngokuba yi-'collagen' (into enika ulusu lwethu amandla kunye nezicubu). Le collagen igqithisileyo ifakwa eluswini nakwizitho zangaphakathi, nto leyo eyenza zibe nkulu kwaye ziqine, njengenxeba elidala. Kodwa endaweni yokuphilisa inxeba, le collagen igqithisileyo inokonakalisa nezihlunu eziphilileyo.

I-Eosinophilic Fasciitis kunye ne-COVID-19

Abantu abanezifo zokuzikhusela komzimba ezifana ne-Eosinophilic Fasciitis bathathwa njengabasemngciphekweni omkhulu wokosulelwa yi-COVID-19 kunabantu ngokubanzi.

Iingcali azikaqiniseki ukuba abantu abanale meko banokuba neempawu eziqatha ze-COVID-19 na. Ke ngoko, kungcono ukulandela iingcebiso zeziphathamandla zempilo, ezifana neZiko loLawulo lweZifo kunye nokuThintela (CDC), ukuze uzikhusele kusulelo.

Ngubani onokuthi afumane esi sifo?

I-Eosinophilic Fasciitis inokuchaphazela nabani na, kodwa ixhaphake kakhulu kubantu abaphakathi kweminyaka engama-30 nama-60 ubudala.

Ukongeza, abantu abaneengxaki ezithile zempilo ezingapheliyo banamathuba amaninzi okufumana esi sifo. Ezinye zezi meko ziquka:

• I-Aplastic anemia (i-aplastic anemia - i-anemia apho ukuveliswa kweeseli zegazi kuncipha khona)
• I-Hemolytic anemia (i-anemia apho iiseli ezibomvu zegazi ziqhekeka ngokukhawuleza)
• I-Lymphoma (umhlaza wenkqubo ye-lymphatic)
• I-leukemia (umhlaza weeseli zegazi)
• Ezinye iintlobo zesifo se-thyroid

Kuqheleke kangakanani oku?

I-Eosinophilic Fasciitis sisifo esingaqhelekanga . Okwangoku, linani elincinci kakhulu lamatyala, malunga nama-300, axeliweyo kwiijenali zesayensi kwihlabathi liphela. Nangona kunjalo, mhlawumbi ngenxa yokungafumani ngxelo ngokwaneleyo okanye ukungafumani ngxelo ipheleleyo, inani lamatyala linokuba phezulu kakhulu.

I-Eosinophilic Fasciitis ichaphazela njani umzimba wam?

Njengoko besikhe sathetha ngaphambili, le meko ibangelwa kukudumba kwe-fascia, izicubu ezincinci neziguquguqukayo ezingaphantsi kolusu. Olu maleko we-fascia ugubungela kwaye ukhusela izihlunu zethu kunye nezinye izitho zangaphakathi. Ukwabamba ulusu kunye nezihlunu endaweni yazo kwaye uzixhase xa zishukuma.

Cinga ngale nto, le fascia inceda ukugcina amalungu ethu eguquguquka, kodwa ingaxhomekeki nje kuphela. Kodwa kumntu one-'Eosinophilic Fasciitis', le fascia membrane iyavuvukala, ityebe kancinci kancinci, ize iqine. Ekugqibeleni, oku kuvutha kwenza kube nzima ukuhambisa ulusu kunye nezihlunu ezijikeleze yona. Ukuba ayinyangwa, le fascia inokunamathela kwindawo enye ize iqine. Oku ngamanye amaxesha kubizwa ngokuba yi-'contracture'. Oko kukuthi, imeko apho ilungu lingenakwandiswa okanye ligobe.

Endaweni yokuba i-fascia ithambe ngendlela eqhelekileyo, amalungu omzimba achaphazelekayo aba buhlungu okanye kube nzima ukuwashukumisa.

Amalungu omzimba achaphazeleka kakhulu zezi:

• Izandla (ingakumbi intende yesandla, oko kukuthi, ingaphakathi lesandla)
• Imilenze (ingakumbi ngaphambili, kanye ethanjeni lesinqe)
• Iindawo ezidibeneyo okanye ezikufutshane

Nangona ingaqhelekanga, le meko inokuchaphazela nolusu ebusweni, esifubeni, nasesiswini.

Ezinye izigulana ezine-Eosinophilic Fasciitis zinokuba nokuvuvukala kwamalungu okufana ne-Rheumatoid Arthritis. Ukuba oku kuvuvukala kwamalungu akulawuleki, i-cartilage esemalungeni inokonakala, nto leyo ekhokelela kwi-arthritis yexesha elide.

Kwakhona, ukuba esi sifo sichaphazela i-fascia esesandleni sakho okanye esihlahleni, ukudumba kunokubangela ukuba i-median nerve, enye ye-nerves ephambili esandleni, icinezelwe, nto leyo ebangela imeko ebizwa ngokuba yiCarpal Tunnel Syndrome (ukuba ndindisholo, iintlungu, kunye nobuthathaka esandleni).

Into ebalulekileyo kukuba i-Eosinophilic Fasciitis yimeko enokutshintsha kwaye ikhule ngokukhawuleza. Ungaqala ukuqaphela iziphumo ezibonakalayo kwixesha elifutshane, njengeeveki ezimbalwa. Ke ngoko, ukuba ubona naziphi na iimpawu okanye utshintsho emzimbeni wakho, bonana nogqirha ngokukhawuleza.

Ziziphi iimpawu ze-Eosinophilic Fasciitis?

Ngoko ke, ufanele uyicinge njani le nto? Nazi ezinye zeempawu eziphambili:

• Intlungu yemisipha .
• Ulusu oluthambileyo .
• Ukudumba okanye ukudumba .
• Iimpawu ze-'Carpal Tunnel Syndrome' (ezifana nokungaziva mnandi, iintlungu, ubuthathaka esandleni).
• I-Arthritis (i-arthritis - ukudumba kwamalungu, iintlungu, ukuqina kwamalungu kusasa).
• Ulusu luvakala lutyebile kwaye luqinile kunesiqhelo.
• Kwezinye iindawo, ulusu lubonakala lunamaqhuqhuva kwaye lurhabaxa, njengexolo leorenji (isikhumba esinamaqhuqhuva okanye inkangeleko "yepeau d'orange").

Yintoni isizathu soku?

Inyaniso kukuba, iingcali azikayazi eyona nto ibangela i-Eosinophilic Fasciitis. Njengezifo ezininzi zokuzikhusela komzimba, inokuvela ngequbuliso, ngamanye amaxesha ngaphandle kwesizathu esicacileyo.

Nangona kunjalo, ezinye izifundo zifumanise ukuba ezi zifo zokuzikhusela komzimba zinokuthi ``zibangelwe`` zizinto ezithile. Oko kukuthi, esi sifo sinokuvela ngenxa yento ethile. Umzekelo:

• Ezinye iintlobo zosulelo .
• Ezinye iimpembelelo ze-allergy .
• Ukusebenzisa amayeza athile.
• Ukusebenzisa amayeza athile.

Abanye abantu abane-Eosinophilic Fasciitis bathi iimpawu zabo zokuqala zenzeka emva kokusebenza nzima ngokomzimba , njengokubaleka, ukuphakamisa iintsimbi, okanye ukwenza umthambo, okanye xa besenza umsebenzi ofuna umgudu omkhulu kwiingalo okanye emilenzeni.

Kungcono ukuthetha nogqirha wakho ngezinto ezinokubangela ukuba ube nesifo sokuzikhusela komzimba esifana nesi.

Oogqirha bayixilonga njani le sifo? (Ukuxilongwa)

Ukuba unale mpawu, ugqirha angenza uvavanyo oluninzi ukuze afumanise ukuba unayo na i-Eosinophilic Fasciitis:

1. I-Fascia Biopsy: I-biopsy kuxa ugqirha wakho ethatha isampuli encinci yezicubu zakho aze azithumele kwilebhu ukuze azijonge phantsi kwe-microscope. Oku kuquka ukuthatha iqhekeza elincinci lesikhumba esichaphazelekayo kunye ne-fascia engaphantsi kwayo aze ayihlole. Kwiimeko ezininzi, le yeyona ndlela ithembekileyo yokuxilonga imeko.

2. Uvavanyo lwegazi: Ukuba une-Eosinophilic Fasciitis, usenokuba namanqanaba aphezulu ohlobo lweseli emhlophe yegazi ebizwa ngokuba yi-Eosinophils egazini lakho (apho isifo sifumene khona igama laso). Nangona kunjalo, uvavanyo lwegazi lodwa alunakuqinisekisa isifo. Rhoqo, kufuneka i-biopsy.

3. Uvavanyo lwemifanekiso: Uvavanyo olufana ne-MRI (Magnetic Resonance Imaging) lunokunceda ekuchongeni ukudumba emzimbeni, ingakumbi kwi-fascia nakwizicubu ezingqongileyo. Nangona kunjalo, njengovavanyo lwegazi, alunazo iinkcukacha ezithile njenge-biopsy yokufumanisa isifo.

Unyango lwe-Eosinophilic Fasciitis

Amaxesha amaninzi, iimpawu zinokuphela zodwa ngaphandle konyango. Kodwa uninzi lwexesha, oogqirha banyanga i-Eosinophilic Fasciitis ngohlobo lwamayeza abizwa ngokuba yi-corticosteroids . Ezi luhlobo lwe-steroid.

Ii-corticosteroids zisebenza ngokunciphisa ukudumba emzimbeni kunye nokunciphisa inkqubo yomzimba yokuzikhusela esebenza kakhulu. I-Prednisone yeyona corticosteroid isetyenziswa kakhulu.

Ukongeza kwi-corticosteroids, ugqirha wakho unokumisela nezinye iindlela zonyango, ezifana nezi:

• `Ii-NSAID`: Amayeza angengo-steroidal alwa nokuvuvukala (ii-NSAID) afumaneka kwikhemesti – umzekelo, i-ibuprofen kunye ne-diclofenac – anokunciphisa iimpawu ezifana nentlungu kunye nokudumba. Nangona kunjalo, ukuba sele usebenzisa ii-`corticosteroids`, thetha nogqirha wakho ngaphambi kokuba usebenzise ii-`NSAID`. Musa ukuthatha ii-`NSAID` kangangeentsuku ezingaphezu kwe-10 ngexesha ngaphandle kwemvume kagqirha wakho.
• Amayeza okucinezela amajoni omzimba: Ngokuxhomekeke kubukhali bemeko yakho, ugqirha wakho unokukunika amanye amayeza (umz., iMethotrexate) acinezela amajoni omzimba asebenza kakhulu abangela i-Eosinophilic Fasciitis.
• Unyango lomzimba: Unyango lomzimba lunokunceda ukolula nokukhulula i-fascia yakho xa iqinile, kwaye luncede ukugcina amalungu eshukuma. Ugqirha wakho okanye ingcali yonyango lomzimba uza kukufundisa imithambo kunye nokolula okufanelekileyo kwiimpawu zakho.
• Ukunyanga ezinye iimeko: Ungaziva ukhululekile ngakumbi ngokunyanga iimpawu zezinye iimeko, ezifana ne-carpal tunnel syndrome okanye i-arthritis.
• Utyando: Ukuba i-Eosinophilic Fasciitis yakho inzima ngokwaneleyo ukuba ibangele ukudumba, kunokufuneka utyando ukuze ukhulule okanye ususe inxalenye ye-fascia yakho (ukukhululwa kwe-fascial). Oku kudla ngokuba yindlela yokugqibela.

Ungazilawula njani iimpawu?

• Kubaluleke kakhulu ukusela amayeza kanye njengoko ugqirha etshilo, kangangexesha elimiselweyo.
• Ukuba ugqirha wakho okanye ingcali yezonyango ikunika ukolula okanye eminye imithambo, yenza loo mithambo amaxesha amaninzi njengoko bekuxelela ukuba uncede ukolula i-fascia echaphazelekayo. Nangona oku kunokuba nzima, kunokuba luncedo ukuba uyaqhubeka nokuyenza.
• Ukuba uneCarpal Tunnel Syndrome, kunokufuneka unxibe i-brace ukuze ugcine isihlakala sakho sisendaweni yaso ngelixa ulele. Sisebenzise njengoko ugqirha wakho ekuyalele.

Ndiza kuziva ngcono ngokukhawuleza kangakanani emva konyango?

Ukuvuvukala okubangelwa yi-Eosinophilic Fasciitis kufuneka kuqale ukuphela kwiiyure ezimbalwa emva kokuthatha idosi yokuqala ye-corticosteroids. Olu ncedo lunokuba lolwexeshana, kwaye iimpawu zinokubuya njengoko iyeza liphela. Ke ngoko, kubalulekile ukuthatha iyeza ixesha lonke elichazwe ngugqirha wakho.

Ngaba i-Eosinophilic Fasciitis ingathintelwa?

Ngelishwa, akukho ndlela ithile yokuthintela esi sifo. Iingcali azazi ukuba yintoni ebangela izifo ezibangelwa kukuzikhusela komzimba okanye indlela ezibangelwa ngayo, ngoko ke azinakutsho ukuba uza kuzifumana nini okanye kutheni.

Yintoni emele ilindelwe ngumntu onesi sifo?

Ukuba ufunyaniswe une-Eosinophilic Fasciitis, kufuneka ulindele ukuba iimpawu zakho ziya kulawula okwethutyana. Ukuba ubona naluphi na utshintsho kwiimpawu zakho, ingakumbi ukuba ziya zisiba mandundu, thetha nogqirha wakho ngoko nangoko.

Njengoko besitshilo ngaphambili, akukho nyango loku. Abantu abaninzi baphila nalo iminyaka embalwa, emva koko iimpawu ziyaphela (ziye kwi-'remission'). Abanye abantu abaphindi bafumane kwakhona, kodwa abanye banokuba neempawu ezibuyayo kamva ('recur').

Ngaba awuzukukwazi ukuya emsebenzini okanye esikolweni?

Ukuba ungenza umsebenzi wakho okanye umsebenzi wesikolo ngaphandle kokubeka uxinzelelo olukhulu kwi-fascia yakho echaphazelekayo, kufuneka ukwazi ukubuyela emsebenzini okanye esikolweni ude uphile kwi-Eosinophilic Fasciitis. Nangona kunjalo, ugqirha wakho uza kukuxelela ukuba zeziphi izinto omele uziphephe ude uphile. Kubalulekile ukulandela le miyalelo.

Qiniseka ukuba uthetha nogqirha wakho kwaye ufumane imvume ngaphambi kokuba uqalise imisebenzi enzima yomzimba efana nokubaleka, ukuphakamisa iintsimbi, okanye ukwenza umthambo.

Ufanele uye nini kugqirha?

• Ukuba ubona naziphi na iimpawu ezintsha ezandleni zakho, ezinyaweni, okanye emalungwini – ingakumbi ukuba unentlungu okanye ukudumba okungapheliyo emva kweentsuku ezimbalwa zokuphumla – bonana nogqirha ngoko nangoko.
• Ukuba sele ufunyenwe une-Eosinophilic Fasciitis, xelela ugqirha wakho ngokukhawuleza ukuba iimpawu zakho ziya zisiba mandundu, okanye ukuba ubona nayiphi na inxalenye yomzimba wakho iqina okanye ingenamsebenzi.

Ufanele uye nini kwiYunithi yoNyango oluNgxamisekileyo (i-ETU) ?

Ukuba ngequbuliso awukwazi ukushukuma okanye ukusebenzisa inxalenye yomzimba wakho, okanye ukuba ufumana iintlungu ezinganyamezelekiyo, yiya kwigumbi likaxakeka elikufutshane ngoko nangoko .

Yeyiphi imibuzo omele uyibuze ugqirha?

Xa usiya kugqirha, ungabuza imibuzo efana nale:

• Ngaba ndine-Eosinophilic Fasciitis, okanye yinto eyahlukileyo?
• Iimpawu zam zingaba mandundu ngokukhawuleza kangakanani?
• Luhlobo luni lonyango endiludingayo? Ndiza kuludinga ixesha elingakanani unyango?
• Ngaba ndiza kufuna utyando?
• Ndingaphinda ndiqalise nini ukwenza umthambo oqhelekileyo?
• Le meko ichaphazela njani ubomi bam bemihla ngemihla?

Ezinye zezona zinto zibalulekileyo ekufuneka sizikhumbule kweli bali zezi:

I-Eosinophilic fasciitis yimeko engaqhelekanga kodwa enzulu enokukuchaphazela ngokukhawuleza. Ukuba ubona iintlungu ezintsha, ukudumba, okanye ukuqina ezandleni okanye ezinyaweni zakho, ingakumbi ukuba azipheli kwiintsuku ezimbalwa, musa ukulibazisa ukubona ugqirha. Ekubeni le meko inokukhula ngokukhawuleza , okukhona ujonga iimpawu zakho ngokukhawuleza, kokukhona ugqirha wakho enokufumana unobangela ngokukhawuleza aze aqalise unyango olufunekayo.

Ugqirha wakho uza kongeza ii-corticosteroids kunye nolunye unyango ukuba kuyimfuneko ukunceda ukulawula iimpawu zakho. Musa ukoyika, kodwa qaphela iimpawu zakho kwaye ulandele imiyalelo kagqirha wakho ngononophelo. Ndikunqwenelela impilo ekhawulezileyo!

I- Eosinophilic Fasciitis, i-Eosinophilic Fasciitis, Izifo Zesikhumba, i-Fascia, Intlungu Yamalungu, Intlungu Yemisipha, Izifo Zokuzikhusela Ngokwazo