Xa ugqirha wakho ekunika iGlasdegib okanye umntu okwintsapho yakho, kuyinto eqhelekileyo ukuba nemibuzo emininzi ngayo. Lithini eli yeza? Kwenzeka ntoni ngalo? Ngaba kukho naziphi na iziphumo ebezingalindelekanga? Masithethe ngako konke oku ngendlela enobuhlobo nelula. Emva kokufunda eli nqaku, uya kuba nokuqonda okungcono ngeli yeza.
Yintoni le Glasdegib?
Ngamafutshane, iGlasdegib liyeza elisetyenziselwa ukunyanga uhlobo lomhlaza olubizwa ngokuba yi-leukemia. Liza likwimo yepilisi.
Kukho iproteni ekhethekileyo emzimbeni wethu enceda iiseli zomhlaza zikhule, oko kukuthi, ziphindaphindeke kwaye zisasazeke. Okwenziwa leli yeza kukuyeka ukusebenza kwaloo proteni. Emva koko ukukhula nokusasazeka kweeseli zomhlaza kulawulwa kakhulu. Le yindlela elula eli yeza elisebenza ngayo.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza
Kubaluleke kakhulu ukuba ugqirha wakho ayazi imbali yakho epheleleyo yezonyango ngaphambi kokuba akunike eli yeza. Ngoko ke, ukuba unenye yezi meko zidweliswe ngezantsi, qiniseka ukuba uxelela ugqirha wakho ngayo.
- Ukuba unesifo sentliziyo.
- Ukuba unezinga eliphantsi okanye eliphezulu lee-electrolytes ezifana ne-magnesium, i-potassium, okanye i-sodium egazini lakho.
- Ukuba ukubetha kwentliziyo akuhambelani kakuhle.
- Ukuba unesifo sezintso.
- Ukuba unesifo sesibindi.
- Ukuba unentlungu yemisipha ngequbuliso okanye ukuqaqamba kwemisipha.
- Ukuba ukhe waba ne-allergy kwiGlasdegib okanye naliphi na elinye iyeza, ukutya, okanye idayi ngaphambili.
- Ukuba ukhulelwe okanye uzama ukukhulelwa.
- Ukuba ungumama oncancisayo.
Ndingayisebenzisa njani le mithi?
Qaphela la manqaku xa usebenzisa eli yeza.
- Ginya le pilisi yonke ngeglasi yamanzi. Musa ukuyiqhekeza, ukuyityumza, okanye ukuyihlafuna.
- Zama ukuyithatha ngexesha elifanayo yonke imihla, kanye njengoko ugqirha wakho ekuyalele.
- Ungayithatha le nto ngaphambi okanye emva kokutya, kodwa ukuba uziva isisu sibuhlungu, kungcono ukuyithatha kunye nokutya.
- Musa ukuthatha ngaphezu komlinganiselo ochazwe ngugqirha wakho.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga, ugqirha wakho unokugqiba ekubeni atshintshe idosi yakho okanye ayeke ukuyisebenzisa okwethutyana. Ungaze utshintshe idosi yakho okanye uyeke ukuyisebenzisa ngaphandle kwengcebiso kagqirha wakho.
Kubalulekile: Eli yeza limiselwe wena wedwa. Ungaze ulinike omnye umntu.
Kuthekani ukuba ndiphoswa lidosi leyeza?
Ukuba ulibele ukuthatha idosi, yithathe kwangoko xa ukhumbula. Nangona kunjalo, ukuba kungaphantsi kweeyure ezili-12 ngaphambi kokuba uthathe idosi elandelayo, yitsibe idosi oyiphosileyo. Endaweni yoko, thatha idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye ukuze ubuyisele idosi oyiphosileyo.
Ungenza ntoni ukuba uthatha amayeza amaninzi kakhulu?
Ukuba ucinga ukuba uthathe amayeza amaninzi kakhulu, yiya kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele ngoko nangoko okanye utsalele umnxeba iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo ukuze ufumane ingcebiso.
Ezinye izinto ezinokusebenzisana nale mithi
Amanye amayeza, ukutya, kunye neziselo zinokusebenzisana neGlasdegib, ngoko ke kubaluleke kakhulu ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo (kuquka iivithamini kunye neemveliso zezityalo).
| Izinto ezinokudibana nale mithi | |
|---|---|
| Ungaze uzithathe ezi zinto kunye. | |
| I-Dronedarone, i-Fluconazole, i-Pimozide, i-Posaconazole, i-Saquinavir, i-Thioridazine | |
| Ezi zinto zinokubangela ukusabela - xelela ugqirha wakho | |
| Amayeza | Ii-antibiotics ezifana ne-Apalutamide, i-Clarithromycin, i-Ketoconazole, i-Carbamazepine, i-Rifampin, i-Ribociclib, ii-antivirals ze-HIV/hepatitis, ii-antifungal, amayeza e-epilepsy, kunye namanye amayeza atshintsha isingqisho sentliziyo. |
| Ezinye izinto | Iimveliso zezityalo ezifana nejusi yegrapefruit kunye ne-St. John's wort. |
Olu luhlu aluphelelanga, ngoko ke xelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo.
Izinto ekufuneka uzilumkele ngakumbi xa usebenzisa amayeza
Ngelixa usela eli yeza, nikela ingqalelo ekhethekileyo kwezi ngongoma ukuze ukhuseleke kwaye ufumane impumelelo kunyango lwakho.
- Ukuhlolwa rhoqo kwezonyango: Ndwendwela ugqirha wakho rhoqo ukuze ujonge ukuba unjani na. Kungathatha ixesha ukuba iziphumo zale mithi zibonakale. Kusenokufuneka wenze uvavanyo lwegazi ukuze ubone ukuba iyeza lichaphazela njani umzimba wakho.
- Ukukhulelwa nokulawula ukuzala: Oku kubaluleke kakhulu . Eli yeza linokubangela iziphene ezinkulu zokuzalwa komntwana ongakazalwa.
- Abafazi: Kuphephe ukukhulelwa ngokupheleleyo ngelixa usela eli yeza kwaye kangangeentsuku ezingama-30 emva kokusela ipilisi yokugqibela. Thetha nogqirha wakho malunga nolawulo lokuzala oluthembekileyo.
- Amadoda: Kuphephe ukuba nguyise womntwana ngelixa usela eli yeza kwaye kangangeentsuku ezingama-30 emva kokusela ipilisi yokugqibela. Qiniseka ukuba usebenzisa indlela yokuthintela ukukhulelwa, njengekhondom, ukuthintela iqabane lakho ukuba lingakhulelwa.
- Ukuncancisa: Kuphephe ukuncancisa ngelixa usela eli yeza kwaye kangangeentsuku ezingama-30 emva kokuthatha ipilisi yokugqibela.
- Ukunikela ngesidoda kunye negazi:
- Kuphephe ukunikela ngesidoda ngelixa usela amayeza kwaye emva kweentsuku ezingama-30 uyekile.
- Kuphephe ukunikela ngegazi ngeli xesha, kuba ubungakanani bamayeza egazini elinikelweyo bunokulimaza umntwana ongekazalwa xa bunikwa umfazi okhulelweyo.
- Ukuzala: Eli yeza lisenokuchaphazela ukuzala. Thetha nogqirha wakho ukuba uneengxaki malunga noku.
Zithini iziphumo ebezingalindelekanga ezinokubakho?
Njengazo zonke iziyobisi, iGlasdegib inokubangela ezinye iziphumo ebezingalindelekanga. Asinguye wonke umntu ozifumanayo, kodwa kubalulekile ukuba uzazi.
| Imiphumela | Inkcazo kunye neempawu |
|---|---|
| Izinto ekufuneka uzazise ugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi okanye umqala. |
| Ukopha okungaqhelekanga | Indle emnyama ehlala ixesha elide, ukuhlanza okumdaka okufana nekofu egayiweyo, umchamo obomvu okanye omdaka, amabala amancinci abomvu/omfusa eluswini, kunye nokudumba ngamanye amaxesha. |
| Utshintsho kwisantya sentliziyo | Ukuziva ngathi intliziyo yakho ibetha ngokukhawuleza, isiyezi, ukuquleka, iintlungu zesifuba, ubunzima bokuphefumla. |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, ukukhohlela, umphimbo obuhlungu. |
| Iiseli ezibomvu zegazi ezisezantsi | Ukudinwa okungaqhelekanga, isiyezi, intloko ebuhlungu, ubunzima bokuphefumla. |
| Ukonakala kwemisipha | Ukudinwa okungaqhelekanga, iintlungu zemisipha, umchamo otyheli okanye omdaka, ukuncipha kokuphuma komchamo. |
| Ukuba iyaqhubeka okanye iyakhathaza, xelela ugqirha wakho. | |
| Ezinye izifo ezincinci | Utshintsho kwincasa, ukungabi namdla wokutya, iintlungu zamalungu, isicaphucaphu, izilonda zomlomo, ukudumba kwamaqatha, izandla okanye iinyawo, ukudinwa okungaqhelekanga. |
Ungayigcina njani iyeza?
- Yigcine kwindawo ekhuselekileyo kude nabantwana nezilwanyana zasekhaya.
- Gcina kubushushu begumbi (phakathi kwama-20 nama-25 degrees Celsius).
- Lahla amayeza aphelelwe lixesha.
- Buza ugqirha wakho indlela yokulahla ngokukhuselekileyo amayeza angasafunekiyo okanye aphelelwe lixesha.
Umyalezo Wokuya Ekhaya
- I-Glasdegib liyeza le-leukemia. Soloko uyithatha kanye njengoko ugqirha wakho ekuxelele, ngexesha elifanelekileyo. Musa ukuphula, ukutyumza, okanye ukuhlafuna ipilisi.
- Xelela ugqirha wakho malunga neminye imithi, iivithamini, okanye iimveliso zezityalo ozisebenzisayo.
- Kuphephe ukukhulelwa ngelixa usebenzisa eli yeza kwaye emva kweentsuku ezingama-30 uyekile. Oku kubalulekile kubafazi nakumadoda.
- Xelela ugqirha wakho ngokukhawuleza ukuba ubona ukopha okungaqhelekanga, iintlungu esifubeni, ubunzima bokuphefumla, okanye iimpawu ze-allergy enzima.
- Eli yeza lelakho kuphela. Ungaze wabelane ngalo nabanye. Thetha ngokukhululekileyo nogqirha wakho ngayo nayiphi na imibuzo onokuba nayo.
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