Ngaba une-hATTR (i-amyloidosis ebangelwa yi-transthyretin), imeko engaqhelekanga yemfuza? Ngaba udiniwe ziintlungu ezingapheliyo, ukungaziva, okanye ukuphelelwa ziimvakalelo ezandleni nasezinyaweni zakho? Ukuba kunjalo, ugqirha wakho usenokuba ukuxelele ngesitofu sokugonya esibizwa ngokuba yi-Inotersen. Namhlanje, masithethe ngokufutshane malunga nokuba yintoni le yeza, yintoni eliyenzayo, kunye noko kufuneka ukuqaphele xa ulisebenzisa.
Luhlobo luni lweyeza i-Inotersen?
Ngamafutshane, i-Inotersen sisitofu sokugonya esinikwa ukunyanga iingxaki zemithambo-luvo kubantu abanesifo esibizwa ngokuba yi -hATTR . Kwesi sifo se-hATTR, iproteni eveliswa emzimbeni wethu iqokelelana ngaphezu kwemfuneko kwaye yonakalisa imithambo-luvo. Eli yeza lisebenza ngokunciphisa ukuqokelelwa kweproteni emzimbeni . Emva koko iimpawu ozivayo, ezinje ngentlungu, ukungaziva, kunye nokulahlekelwa yimvakalelo emalungeni akho, ziqala ukuncipha kancinci kancinci. Eli yeza lingafumaneka kwimarike phantsi kwegama elithi `(Tegsedi)`.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza
Ngaphambi kokuba uqale ukusebenzisa eli yeza, kukho izinto ekufuneka uzixoxe nogqirha wakho. Olu lwazi lubaluleke kakhulu kukhuseleko lwakho.
- Ukuba unesifo sezintso: Sixelele ngazo naziphi na iingxaki zezintso.
- Ukuba inani leeseli zegazi liphantsi: Umzekelo, ukuba sele ufunyenwe uneeseli ezimhlophe zegazi, iiseli ezibomvu zegazi, okanye iiplatelets eziphantsi, yazisa ugqirha wakho.
- Ukuba unayo nayiphi na i-allergies: Sixelele ukuba unayo nayiphi na enye into, ukutya, okanye idayi, kungekuphela nje kwi-Inotersen.
- Ukuba ukhulelwe okanye uceba ukukhulelwa: Kubalulekile ukuxelela ugqirha wakho ngale nto, njengoko kufuneka kuthathwe unyango olukhethekileyo ngeli xesha.
- Ukuba ungumama oncancisayo: Kubalulekile ukuqaphela oku nangona ngexesha lokuncancisa.
Ungayisebenzisa njani i-vaccine?
Olu lujovo olufakwa ngaphantsi kwesikhumba . Ungakhathazeki, ugqirha wakho okanye umongikazi uza kukubonisa ngqo indlela yokuzijova. Kubaluleke kakhulu ukuthatha ijovo kanye njengoko ugqirha wakho ekuxelela, ngosuku olufanelekileyo, nangomlinganiselo ofanelekileyo. Qhubeka uyisebenzisa de akuxelele ukuba uyeke.
Kubaluleke kakhulu: Ungaze ulahle iinaliti neesirinji ezisetyenzisiweyo enkunkuma. Zifanele zibekwe kwisikhongozeli esikhethekileyo se-sharps. Ukuba awunayo, buza ugqirha wakho malunga nendlela yokuzifumana.
Uza kufumana incwadana yemiyalelo ekhethekileyo ethi ``(MedGuide)`` kunye nale yeza. Khumbula ukuyifunda ngononophelo ngalo lonke ixesha.
Ungenza ntoni ukuba uthatha amayeza amaninzi kakhulu?
Ukuba ucinga ukuba uthathe amayeza amaninzi kakhulu, yiya kwiSebe lezeMpilo eziNgxamisekileyo (ETU) lesibhedlele esikufutshane ngoko nangoko . Okanye utsalele umnxeba iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo .
Kuthekani ukuba ndiphoswa lidosi leyeza?
Thatha idosi oyiphosileyo ngokukhawuleza xa ukhumbula. Nangona kunjalo, ukuba idosi yakho elandelayo ingaphantsi kweentsuku ezimbini, yitsibe idosi oyiphosileyo uze uthathe idosi yakho elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye, oko kukuthi, idosi ephindwe kabini.
Ezinye izinto ezinokusebenzisana nale mithi
Kufuneka ulumke kakhulu ukuba usebenzisa amanye amayeza ngelixa usebenzisa la mayeza, kuba anokusebenzisana. Xelela ugqirha wakho ngawo onke amayeza, iivithamini, kunye namayeza esintu owasebenzisayo.
Apha ngezantsi kukho amayeza anokuchaphazela eli yeza.
| Udidi lweziyobisi | Imizekelo |
|---|---|
| Izinto zokunciphisa igazi | I-Warfarin, i-Enoxaparin, i-Aspirin, i-Clopidogrel, i-Apixaban, i-Rivaroxaban |
| Iipilisi zokubulala iintlungu (ii-NSAID) | Amayeza anjenge-Ibuprofen kunye ne-Naproxen |
| Ii-antibiotics kunye namanye amayeza osulelo oluthile | I-Acyclovir, iGentamicin, iVancomycin, iAmphotericin B |
| Iziyobisi zomchamo | Amayeza afana neFurosemide |
| Amanye amayeza | I-Cisplatin, iCyclosporine, iZoledronic acid, iPamidronate |
Olu luhlu aluphelelanga, ngoko ke kungcono ukuxelela ugqirha wakho ngayo yonke into oyithathayo.
Izinto ekufuneka uzilumkele xa usebenzisa amayeza
- Bona ugqirha wakho rhoqo: Jonga ugqirha wakho rhoqo ukuze ubone ukuba unjani na kwaye ukuba amayeza ayasebenza na. Mxelele ukuba iimpawu zakho ziya zisiba mandundu okanye azibi mandundu.
- Lumka ngevithamini A: Ugqirha wakho angakuxelela ukuba uthathe izongezo zevithamini A ngelixa usebenzisa eli yeza. Oku kungenxa yokuba eli yeza linokunciphisa inqanaba levithamini A emzimbeni. Thatha izongezo zevithamini A njengoko ugqirha wakho ekuxelela. Kwakhona, thetha naye malunga nokutya kwakho.
Zithini iziphumo ebezingalindelekanga ezinokubakho?
Njengalo naliphi na iyeza, eli linokubangela iziphumo ebezingalindelekanga kwabanye abantu. Ezinye zimbi kakhulu, ezinye ziqhelekile. Kubalulekile ukuzazi ezi zinto.
| Imiphumela | Inkcazo |
|---|---|
| Izinto omele uzixelele ugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi okanye umqala. |
| Ukulimala kwezintso | Ukuncipha kokuphuma komchamo, ukudumba kwamaqatha, izandla, okanye iinyawo. |
| Ukulimala kwesibindi | Intlungu kwicala lasekunene lesisu, ukungabi namdla wokutya, isicaphucaphu, ukutyheli kolusu okanye amehlo, umchamo otyheli/omdaka omnyama. |
| Ukopha okungaqhelekanga okanye ukukrweleka | Ulusu olukrweleka lula, oluphuma igazi empumlweni, noluphuma igazi kwiintsini. |
| Istroke | Ukungaziva/ukungaziva ngequbuliso kwelinye icala lobuso, ingalo, okanye umlenze, ubunzima bokuthetha, ubunzima bokuhamba, intloko ebuhlungu kakhulu. |
| Ukuba iyaqhubeka okanye iyakhathaza, xelela ugqirha wakho. | |
| Intlungu kunye nokubomvu kwindawo yokutofa | Impendulo yendawo yokujova |
| Intloko ebuhlungu | |
| Isicaphucaphu | |
| Ifiva | |
| Ukudinwa | |
Uligcina njani iyeza?
Kubaluleke kakhulu ukugcina eli yeza ngokufanelekileyo.
- Eyona ndlela ilungileyo: Gcina efrijini. Kodwa ungaze uyiqandisise. Gcina kwiphakheji yayo yokuqala ide ilungele ukusetyenziswa.
- Enye indlela: Ungagcina eli yeza kubushushu begumbi (phakathi kwama-20-25 Celsius) ukuya kuthi ga kwiiveki ezi-6. Nangona kunjalo, ukuba uyaligcina, kufuneka ulikhusele ekukhanyeni nasebushushwini. Lahla nayiphi na intsalela emva kweeveki ezi-6.
- Qiniseka ukuba uyigcina kude nabantwana nezilwanyana zasekhaya.
Ungaze ulahle amayeza aphelelwe lixesha okanye angasetyenziswanga enkunkuma okanye endlwini yangasese. Buza ugqirha wakho ukuba ungawalahla njani ngokukhuselekileyo.Uza kukuxelela eyona ndlela ilungileyo yokwenza oko.
Umyalezo Wokuya Ekhaya
- I-Inotersen sisitofu sokugonya iingxaki zemithambo-luvo ezibangelwa yimeko ebizwa ngokuba yi-hATTR.
- Ngaphambi kokuba uqale amayeza, xelela ugqirha wakho ngazo naziphi na ezinye izifo onazo kunye nawo onke amayeza owasebenzisayo.
- Funda indlela yokutofa isitofu ngendlela efanelekileyo. Lahla iinaliti ezisetyenzisiweyo ngokukhuselekileyo.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezinzulu, ezinje ngokungezwani komzimba, iingxaki zezintso okanye zesibindi, okanye ukukhubazeka komzimba, xelela ugqirha wakho ngoko nangoko.
- Gcina iyeza efrijini okanye njengoko ugqirha wakho ekuyalele.
- Ukuba unemibuzo malunga nale yeza, ungaze woyike ukubuza ugqirha wakho.
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