Ii-antibiotics ze-Fluoroquinolone: ​​Masiyazi kakuhle iingozi kunye nemiphumo emibi

Mhlawumbi unikwe i -antibiotic yosulelo lwebhaktiriya xa uye kugqirha. Ezinye zezi zinamandla kakhulu kwaye zinokunyanga usulelo ngokukhawuleza. Kodwa ubusazi na ukuba kukho ii-antibiotics ezinamandla ezinokuba nemiphumo emibi ngakumbi? Ii-Fluoroquinolones ludidi lwamayeza asetyenziswa kuphela kwiimeko ezikhethekileyo. Namhlanje, siza kuthetha ngayo yonke into ngendlela elula necacileyo.

Zithini ezi fluoroquinolones?

Ngamafutshane, la liqela lee-antibiotics ezisetyenziselwa ukunyanga okanye ukuthintela usulelo oluthile lweebhaktheriya. Nangona zafunyanwa ngeminyaka yoo-1960, oogqirha baqala ukuzisebenzisa kakhulu ngeminyaka yoo-1970 noo-1980. Ngelo xesha, la mayeza ayethandwa kakhulu. Ayesebenza kakhulu ekunyangeni iintlobo ngeentlobo zezifo, ukusuka kusulelo lomchamo ukuya kwi-pneumonia. Kwakulula ukuwasela njengepilisi kanye okanye kabini ngemini, okwenza kube lula ukuwasela. Ayefunwa kakhulu ngoogqirha kuba ayenceda ngokukhawuleza nangona amanye amayeza okubulala iintsholongwane engasebenzi. Nangona kunjalo, ingxaki yayikukuba abanye abantu baqala ukufumana iziphumo ebezingalindelekanga ezibi kakhulu ezivela kula mayeza. Kwakhona, ngenxa yokuba ayesetyenziswa ngokungeyomfuneko kuzo zonke izifo, ezinye iibhaktheriya zamelana nala mayeza (ukuxhathisa ii-antibiotic).

Lisebenza njani eli yeza?

Cinga ngebhaktiriya njengomatshini wokukopa. Ihlala isenza iikopi zayo, nto leyo eyonyusa inani leentsholongwane emizimbeni yethu. Ukuze zenze ezi kopi, ibhaktiriya kufuneka yolule ikhowudi yayo yemfuza, oko kukuthi, iDNA yayo. Iienzymes ezikhethekileyo ziyinceda ukuba yolule le DNA. IiFluoroquinolones ziyayimisa iienzymes ezolula iDNA. Emva koko iibhaktiriya azikwazi ukwenza iikopi, oko kukuthi, azikwazi ukuzala. Le yindlela la mayeza alawula ngayo ukusasazeka kwentsholongwane.

Zeziphi izifo ezisetyenziselwa i-fluoroquinolones?

Okokuqala, makhe sijonge izifo eziqhelekileyo ezingafanele zisetyenziswe eli yeza. Ngokubanzi, alikhuthazwa kwezi meko zilandelayo ezinokunyangeka ngezinye ii-antibiotics ezilula:

• I-sinusitis ebukhali
• I-bronchitis ebukhali (i-bronchitis ebukhali)
• Usulelo lwendlela yomchamo olungenangxaki (UTIs)

Nazi ezinye zeemeko apho ugqirha angakunika eli yeza:

• Usulelo oluntsonkothileyo lwendlela yomchamo (UTIs)
• Ukukrala kwemiphunga
• Usulelo lweprostate (iProstatitis)
• Urhudo olubangelwa ziibhaktheriya ezithile
• Iimeko ezinzulu apho iintsholongwane zingena khona egazini, ezifana ne -sepsis

Oogqirha bamazinyo banokubacebisa nakwezinye izifo zamazinyo. Zikwasetyenziswa nakubantu abane-aleji kwezinye ii-antibiotics okanye xa kungekho ezinye iindlela.

Ngawaphi amayeza akwiqela le-fluoroquinolone?

Usenokuba uqhelene nelinye lala magama. La zezona ntlobo ze-fluoroquinolones ezisetyenziswa kakhulu. Ezi ziza ngohlobo lweepilisi, inaliti ye-IV, amathontsi endlebe, kunye namathontsi eliso.

Zithini iziphumo ebezingalindelekanga ezibi zala mayeza?

Le yeyona nxalenye ibalulekileyo kweli nqaku. Asinguye wonke umntu ofumana iziphumo ebezingalindelekanga kwi-fluoroquinolones. Nangona kunjalo, kwabanye abantu, iziphumo ebezingalindelekanga zinokuba yingozi ngokwaneleyo ukubangela umonakalo ongunaphakade. Ngoko ke kubalulekile ukuqaphela oku. Ezinye iziphumo ebezingalindelekanga zinokuvela kwiiyure ezimbalwa emva kokuqala iyeza. Ezinye zinokuvela kwiiveki okanye kwiinyanga emva kokuyeka iyeza. Ezinye zezona ziphumo bezingalindelekanga nezinzima zezi:

• Iingxaki zetendon: Itendon, ingakumbi itendon ye-Achilles engasemva kwesithende, inokudumba, ibe buhlungu, okanye ide iqhekeke.
• Ukonakala kwemithambo-luvo: Oku kubizwa ngokuba yi-peripheral neuropathy. Iimpawu zingabandakanya ukungaziva, ukurhawuzelelwa, kunye nokurhawuzelelwa kwamalungu omzimba. Oku ngamanye amaxesha kunokuba yinto engapheliyo.
• Iingxaki zempilo yengqondo: Ixhala, ukuphazamiseka, ukudideka, ukudakumba, ukubona izinto ezingekhoyo, kwaneengcinga zokuzibulala zinokwenzeka.
• Ukonakala kwe-aorta: Le yimeko engaqhelekanga kodwa iyingozi kakhulu. Ingabangela ukukrazuka okanye ukuqhekeka kwe-aorta (ukuqhekeka kwe-aorta).
• Utshintsho kumanqanaba eswekile egazini: Amanqanaba eswekile egazini anokuba sezantsi okanye aphezulu ngendlela eyingozi kubantu abanesifo seswekile nakubantu abaphilileyo.
• Kwabo bane-myasthenia gravis: Ubuthathaka bemisipha bunokuba mandundu kubantu abanesi sifo.

Wenza ntoni ukuba ufumana uphawu olunje?

Ukuba ufumana naziphi na ezi mpawu zilandelayo ngelixa usela i-fluoroquinolone, yeka ukuthatha amayeza uze ufowunele ugqirha wakho ngoko nangoko. Ukuba unentlungu eqatha okanye ubunzima bokuphefumla, yiya kwigumbi longxamiseko lesibhedlele (ETU) ngoko nangoko.

• Intlungu ngequbuliso, ukudumba, okanye ukuqina kwemisipha, amalungu, okanye izihlunu.
• Ukungaziva mnandi, ukurhawuzelela, okanye ukurhawuzelela emalungeni.
• Ixhala, ukudideka, okanye utshintsho kwimeko yengqondo.
• Ukuziva unesizungu okanye ukubetha kwentliziyo okungaqhelekanga.
• Urhudo olunentlungu enzulu esiswini.

Imibuzo Ebuzwa Rhoqo (Ii-FAQ)

1. Ngaba ii-fluoroquinolones azivumelekanga?

Hayi. La mayeza asasetyenziswa. Kodwa ngoku acetyiswa kuphela kwiintsholongwane ezinzima nezintsonkothileyo, kungekhona iintsholongwane ezilula. Kwakhona, ziyindlela ebalulekileyo kubantu abane-aleji kwezinye ii-antibiotics.

2. Ingaba iBactrim yifluoroquinolone?

Hayi. I-Bactrim yindibaniselwano yee-antibiotics ezimbini ezahlukeneyo (i-sulfamethoxazole kunye ne-trimethoprim). Ayiyonxalenye ye-fluoroquinolone.

3. Ingaba i-Amoxicillin yi-fluoroquinolone?

Hayi. I-Amoxicillin sisibulali-ntsholongwane esikwiqela le-penicillin. Asiyo-fluoroquinolone. I-Fluoroquinolones, ii-antibiotics, i-Ciprofloxacin, i-Levofloxacin, iziphumo ebezingalindelekanga, usulelo lweebhaktheriya, iziphumo ebezingalindelekanga zee-antibiotic