Ngaba wakha wakubona, okanye wakubona ukudumba ngequbuliso kwelinye icala lobuso bakho, imilebe evuvukileyo, ukurhawuzelelwa kwelinye icala lobuso bakho, okanye ukuqhekeka okungaqhelekanga kolwimi lwakho? Ezi zisenokungabi yinto eqhelekileyo. Zisenokuba ziimpawu zesifo esingaqhelekanga esiza kuthetha ngaso.
Yintoni iMelkersson-Rosenthal Syndrome?
Kulungile, makhe sijonge ukuba yintoni iMelkersson-Rosenthal Syndrome, okanye i-MRS ngamafutshane. Ngamafutshane, yimeko engaqhelekanga kakhulu yemithambo-luvo. Oko kukuthi, ichaphazela kakhulu inkqubo yemithambo-luvo ebusweni bethu. Iimpawu eziphambili zale meko kukudumba kobuso, ukuqhekeka okungaqhelekanga kulwimi (njengemingxunya enzulu), kunye nokukhubazeka kobuso, okukukulahlekelwa ngumsebenzi kwelinye okanye kumacala omabini obuso. Khawuthelekelele, ngequbuliso, ikona yomlomo iyatsalwa kwaye awukwazi ukuvala amehlo akho kakuhle.
Le meko 'ye-MRS' ngamanye amaxesha inokuba luphawu lwemeko yexesha elizayo, njengesifo sikaCrohn (imeko yokudumba okungapheliyo kwamathumbu) okanye i-sarcoidosis (isifo esibangela amaqhuqhuva amancinci, avuvukileyo kwiindawo ezahlukeneyo zomzimba). Oogqirha ngamanye amaxesha babiza le meko ngokuthi ``Orofacial Granulomatosis`` . Yimeko ebangela amaqhuqhuva amancinci, anamaqhuqhuva abizwa ngokuba yi-granulomas, ehamba nokudumba okujikeleze ubuso nomlomo.
Ngubani onokufumana le meko 'ye-MRS'? Ixhaphake kangakanani?
Ngoku usenokuba ucinga ukuba, "Ngubani onokuyifumana le nto?" Enyanisweni, le meko ibizwa ngokuba yi-'MRS' inokukhula nangaliphi na ixesha. Nangona kunjalo, ixhaphake kakhulu kubantu abancinci, ngesiqhelo xa bekwiminyaka yabo yokuqala yama-20, xa iimpawu ziqala ukubonakala.
Kodwa xa kufikwa ekubeni ixhaphake kangakanani, i-MRS yimeko engaqhelekanga kakhulu . Kuthiwa ichaphazela ipesenti encinci kakhulu yabemi, malunga ne-0.08%. Kodwa izazinzulu zikholelwa ukuba ngenxa yokuba iimpawu zifana nezinye izifo, kusenokwenzeka ukuba kukho abantu abaninzi abangakhange baxilongwe. Oku kuthetha ukuba kusenokuba kukho abantu abaninzi abaphethwe yile meko kunale nani. Ngoko ke ukuba uneempawu ezifana nezi, ungayeki ukucinga, "Oku kwenzeka kubantu abambalwa kakhulu, akukho ndlela yokuba ndifumane." Eyona nto ibalulekileyo kukufuna ingcebiso kagqirha.
Zithini izizathu ze-'MRS'?
Kulungile, ngoku masibone ukuba yintoni ebangela le meko 'ye-MRS'. Ukuba sithetha inyani, izazinzulu azikakwazi ukufumana unobangela ochanekileyo . Kodwa kukho izinto ezimbalwa ekucingelwa ukuba zinegalelo kule meko:
- Isifo sikaCrohn: Njengoko benditshilo ngaphambili, esi sisifo esingapheliyo sokudumba kwamathumbu. Kufunyaniswe ukuba abantu abanale sifo basengozini enkulu yokuba ne-MRS.
- Ilifa lemfuza: Oku kuthetha ukuba linokudluliselwa kwizizukulwana ngezizukulwana. Ukuba kukho umntu kusapho oye waba nale meko, oko kungaba sisizathu. Kodwa oku akukabonakali okwangoku.
- Ukusabela kwe-Hypersensitivity: Oku kwenzeka xa inkqubo yomzimba yethu yokuzikhusela isabela ngokugqithisileyo kwinto ethile (esiyibiza ngokuba yi-'antigen' okanye 'i-allergen' - oko kuthetha ukuba inokuba yinto ebangela i-allergy). Kufana ne-allergy, kodwa iyinkimbinkimbi ngakumbi.
- I-Sarcoidosis: Esi sisifo esibangela ukuba kubekho amaqhuma amancinci (iigranuloma) kwiindawo ezahlukeneyo zomzimba. Esi sifo sikwacingelwa ukuba sinxulumene ne-MRS.
- Usulelo olubangelwa yintsholongwane okanye yibhaktiriya: Kukho uluvo lokuba le meko ngamanye amaxesha inokwenzeka emva kosulelo olubangelwa yintsholongwane okanye yibhaktiriya.
Ingaba i-'MRS' sisifo esizikhuselayo emzimbeni (Autoimmune disease)`?
Ngoku abanye abantu basenokuzibuza, "Ngaba esi `sisifo esizikhuselayo emzimbeni'?" Oko kukuthi, ngaba yimeko apho amajoni omzimba wethu ahlasela iiseli zethu eziphilileyo? Enyanisweni, 'i-MRS ' ayithathwa njengesifo esizikhuselayo emzimbeni.
Oku kuhluzwa njengesifo semithambo-luvo . Oko kuthetha ukuba yingxaki yengqondo okanye inkqubo yemithambo-luvo. Ikwabizwa ngokuba sisifo se-granulomatous . Oko kuthetha ukuba yimeko engapheliyo, evuvukileyo, enamaqhuqhuva (i-granuloma) eyenzeka kwizicwili zomzimba. Uyaqonda? Ngoko ke ayiweli ngqo kudidi lwe-"autoimmune."
Zithini iimpawu ze-'MRS'?
Kulungile, ngoko ke makhe sijonge iimpawu zale meko ye-'MRS', okanye imeko ye-'(Orofacial Granulomatosis)' endiyikhankanyileyo ngaphambili. Kukho iimpawu ezintathu eziphambili ezibonakala kule nto. Ezi zibizwa ngokuba yi-'classic triad of symptoms' .
1. I-Facial palsy: Le yimeko apho kukho ubuthathaka okanye ukungaziva mnandi kwelinye icala lobuso, ngamanye amaxesha kumacala omabini. Oku kusenokungabikho kwizigaba zokuqala, kodwa kunokubonakala kwizigaba zamva nje. Njengoko isifo siqhubeka, ixesha lokukhubazeka linokwanda. Khawuthelekelele, ngequbuliso ungakwazi ukuhambisa elinye icala lomlomo wakho, unengxaki yokuvala amehlo akho, okanye uphuma ikona yomlomo wakho xa usela amanzi.
2. Ukudumba kobuso: Abantu abane-MRS badla ngokudumba kobuso (i-Orofacial edema). Ukudumba komlomo (i-Cheilitis granulomatosis) kuxhaphake kakhulu. Umlebe ongaphezulu udla ngokudumba ngaphambi komlebe ongezantsi. Imilebe isenokuba yomile, iqhekeke, ibe buhlungu, kwaye inokuba mdaka-bomvu. Kwabanye abantu, imilebe inokuba lukhuni njengelitye. Ayizizo kuphela imilebe, kodwa nezidlele, iinkophe, kwaye ngamanye amaxesha nentloko yentloko inokudumba. Oku kudumba kunokuba nzima ngakumbi kwaye kuhlale ixesha elide njengoko isifo siphinda sivela.
3. Ulwimi olunemingxunya:Oku kubangela ukuba kubekho imifantu enzulu efana nemingxunya phezulu kolwimi. Oogqirha bakwabiza olu lwimi ngokuthi "ulwimi oluqhekekayo" okanye "uLingua plicata". Oku akusoloko kubuhlungu, kodwa abanye abantu banokufumana ukudumba, ukurhawuzelelwa, kunye nokutsha kolwimi. Kunokubangela ukulahlekelwa yincasa kwaye kukhokelele kwiintsholongwane zomlomo.
Into ebalulekileyo kukuba ayinguye wonke umntu onazo zonke ezi mpawu zintathu. Abanye abantu banokuba neempawu enye okanye ezimbini kuphela kwezi zintathu. Abanye banokuba nazo zonke ezintathu.
Ezi mpawu azihlali zikho. Ziyafika zidlule. Okokuqala, zisenokuthatha iiyure ezimbalwa kuphela . Kodwa xa zibuya kamva, zisenokuba nzima ngakumbi kwaye zihlale ixesha elide.
Ezinye iimpawu
Ukongeza kwezi mpawu ziphambili, kunokubakho nezinye iimpawu ezininzi:
- Isiyezi
- Intloko ebuhlungu ye-Migraine
- Ukukhala ezindlebeni (i-tinnitus) okanye ukulahleka kokuva
- Emva kokuba isifo sibi kakhulu kwaye sipholile, amanxeba ngamanye amaxesha anokubonakala ebusweni .
- Ubunzima bokuginya
- Iingxaki zokubona: Amehlo omileyo, ukubona okufipheleyo, kunye nokudumba kwamehlo (uveitis).
Ifunyanwa njani i-MRS?
Ngoku usenokuba uzibuza, "Ndingazi njani ngokuqinisekileyo ukuba le yi-'MRS'?" Enyanisweni, i-'MRS' inzima ukuyifumanisa. Kuba iimpawu zayo zinokudidaniswa nezinye iimeko. Umzekelo, iimpawu zayo zinokufana ne-'Allergic reactions' okanye i-'Bell's palsy', enye imeko ebangela ukukhubazeka kobuso.
Ugqirha udla ngokuxilonga i-MRS ngokujonga imbali yakho ukuba uneempawu ezimbini kwezi zintathu endizikhankanyileyo ngaphambili. Ngamanye amaxesha, ukuqinisekisa ukuxilongwa nokuthintela ezinye iimeko, iqhekeza elincinci lesicwili somlomo wakho linokuthathwa ukuze livavanywe (i-biopsy). Oku kuya kukhangela ubukho be-granulomas.
Kwakhona, ugqirha angakuthumela kwezinye iingcali ezininzi, njengoko oku kunokuchaphazela iinkqubo ezininzi. Ezi ziquka:
- Ingcali ye-aleji
- Ingcali yesikhumba
- Ingcali yeGastroenterologist - Jonga izinto ezifana nesifo sikaCrohn.
- Ingcali yezifo zomzimba
- Ingcali yamehlo
Ngaba ikho indlela yokunyanga i-'MRS'? Zithini iindlela zonyango?
Kulungile, umbuzo omkhulu abantu abaninzi abanawo ngoku ngulo, "Ngaba lukhona unyango olupheleleyo lwale meko 'ye-MRS'?" Okubuhlungu kukuba, akukho nyango luqinisekileyo lwe-'MRS' okwangoku.
Ngamanye amaxesha iimpawu ziyaphela ngaphandle konyango, kodwa zinokuphinda zibuye.
Ngoko ke, uyinyanga njani? Ukuba iimpawu ziyabuya kwaye ziyakhathaza, kukho iindlela ezahlukeneyo zonyango ezinokunceda ukunciphisa iintlungu, ukuthintela usulelo, kunye nokuphucula inkangeleko. Ziquka:
- Ii-antibiotics: Ukuba kukho usulelo lwebhaktiriya.
- Ii-Antihistamines: Zinciphisa iimpawu ezifana ne-allergy kunye nokudumba.
- IiCorticosteroids: La ngamayeza anamandla anciphisa ukudumba nokudumba. Angafakwa njengeenaliti ngqo kwindawo evuvukileyo, okanye njengeepilisi.
- Ii-immunosuppressants: Ezi zinceda ekunciphiseni ukudumba ngokulawula kancinci ukusebenza kwenkqubo yomzimba yokuzikhusela.
- I-Methotrexate: Eli liyeza elilawula amajoni omzimba kwaye linciphisa ukudumba.
- Amayeza angengowe-steroidal anti-inflammatory (NSAIDs): Anciphisa iintlungu kunye nokudumba (umz., i-Ibuprofen, i-Diclofenac).
- Utyando: Ngamanye amaxesha utyando lunokwenziwa ukunciphisa ukudumba kwimilebe evuvukileyo okanye ukunciphisa uxinzelelo kwimithambo-luvo yobuso. Nangona kunjalo, oku akwenzeki rhoqo.
- Izithinteli ze-TNF-alpha: Ezi zikwaluhlobo oluthile lwamayeza anceda ekuthinteleni ukudumba. Zihlala zinikwa ukuba ezinye iindlela zonyango azisebenzi.
Olu nyango lwenzelwe ukulawula iimpawu nokunciphisa ukungonwabi. Ugqirha wakho uya kugqiba unyango olulungele wena.
Ngaba imeko ye-'MRS' ingathintelwa?
Ngaba le meko 'ye-MRS' ingathintelwa? Enyanisweni, ekubeni izazinzulu zingakaziqondi ngokupheleleyo izizathu zoku, akukho ndlela iqinisekisiweyo yokukuthintela. Ke ngoko, kufuneka sigxile ekuqapheleni iimpawu kwangethuba kwaye sifune unyango olufanelekileyo.
Uza kuphila njani u-'Nkosikazi'? Ngaba uza kuphila?
Ikamva liphethe ntoni kumntu one-MRS? Oku kuyahluka ngokwenene kumntu nomntu. Abanye abantu baneempawu ezibuthathaka kakhulu, njengokuba kanye emva kweminyaka embalwa, kwaye ziyaphela zodwa. Kwabanye, iimpawu zinokuvela rhoqo, njengasemva kweentsuku ezimbalwa, kwaye zinokuba mandundu ngalo lonke ixesha.
Le meko inokuba yeyobomi bonke, kwaye ukudumba kunokuba yinto engapheliyo. Kodwa izazinzulu azicingi ukuba esi sifo sichaphazela ubomi bonke. Oko kuthetha ukuba ungaphila ubomi obuqhelekileyo naso, kodwa kufuneka uphile neempawu zaso. Ke ngoko, ukuhlala uqinile engqondweni nako kubaluleke kakhulu.
Imibuzo omele uyibuze ugqirha wakho
Ukuba uneMelkersson-Rosenthal Syndrome, okanye ukrokrela ukuba unayo, kulungile ukubuza ugqirha wakho le mibuzo:
- Ungatsho njani ngokuqinisekileyo ukuba le yiMelkersson-Rosenthal Syndrome? Ngaba ayinakuba yinto eyahlukileyo?
- Zeziphi ezinye iingcali endifanele ndizibone? (umz., ugqirha wesikhumba, ingcali yezifo zengqondo, njl.njl.)
- Ukuba iimpawu ziyaphinda zibuye, kufuneka ndifune nini ingcebiso kagqirha? Zeziphi iimpawu ekufuneka ndizixhalabele ngakumbi?
- Ngaba kufuneka ndivavanywe isifo sikaCrohn okanye i-sarcoidosis?
- Ndingenza ntoni ukuthintela usulelo, ukudumba okungapheliyo, kunye namanxeba?
- Ingaba ucebisa uvavanyo lwemfuza? Lungakuxelela ntoni?
- Ngaba kukho amaqela enkxaso owaziyo anceda abantu abanezi meko? Ngaba kukho naziphi na izibonelelo zokuba ndizibandakanye nawo?
Ngoko ke, zeziphi izinto ezibalulekileyo esifanele sizithathele ekhaya kweli bali?
Isifo iMelkersson-Rosenthal (MRS) sisifo esingaqhelekanga kakhulu esichaphazela imithambo-luvo yobuso. Ukuba ufumana ukudumba kobuso ngequbuliso, ukukhubazeka kobuso, okanye ukuqhekeka okungaqhelekanga kulwimi lwakho, ngokuqinisekileyo kuya kufuneka ubone ugqirha.
Nangona kungekho nyango luthile lokunyanga oku, kukho unyango olusebenzayo lokulawula iimpawu, ukunciphisa ukungonwabi, kunye nokuthintela iingxaki. Ngoko ke ungakhathazeki. Ngokufunyanwa kwangoko kunye nonyango olufanelekileyo, ungaphila kakuhle nale meko. Awuwedwa, kwaye oogqirha bakho kunye nabantu obathandayo banokukunceda.
Isifo sikaMelkersson -Rosenthal, i-MRS, ukudumba kobuso, ukukhubazeka kobuso, ulwimi oluqhekekileyo, i-neuropathy, i-orofacial granulomatosis
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