Ukuba ugqirha wakho ukuxelele okanye umntu okwintsapho yakho ukuba une-Chronic Myelogenous Leukemia (CML), uhlobo lomhlaza wegazi, usenokuba ukhe weva ngeyeza elibizwa ngokuba yiNilotinib. Eli liyeza elibaluleke kakhulu, elikhethekileyo. Ke namhlanje, siza kuthetha ngokulula nangokucacileyo malunga nento ekufuneka uyiqaphele xa usebenzisa eli yeza, indlela yokulisebenzisa ngokuchanekileyo, kunye neziphumo ebezingalindelekanga omele uzilindele.
Yintoni iNilotinib?
Ngamafutshane, iNilotinib liyeza elithile elithintela ukukhula kweeseli zomhlaza. Sibiza ezi ntlobo zamayeza ngokuthi "unyango olujoliswe kulo." Oko kukuthi, eli yeza liya ngqo ekujoliseni iiproteni ezithile kwiiseli zomhlaza, lizithintele ekusebenzeni, kwaye lilawula ukwahlulwa nokukhula kweeseli zomhlaza.
Eli yeza lisetyenziswa kakhulu ukunyanga uhlobo lwe-leukemia olubizwa ngokuba yi -Chronic Myelogenous Leukemia (CML) . Likwathengiswa phantsi kwegama elithi Tasigna .
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale amayeza
I-Nilotinib liyeza elinamandla kakhulu. Ngoko ke, ngaphambi kokuba uqale olu nyango, ugqirha wakho kuya kufuneka abe nomfanekiso opheleleyo wempilo yakho. Ukuba unenye yezi meko zilandelayo, qiniseka ukuba wazise ugqirha wakho.
| Imeko enokuthi ifanele wena |
|---|
| Isifo seswekile |
| Iimeko ezifana nesifo sentliziyo, ukungahambelani kwesantya sentliziyo, okanye i-Long QT syndrome. |
| Isifo sesibindi |
| Ukuba unembali ye-pancreatitis. |
| Ukuba unezinga eliphantsi le-potassium okanye i-magnesium egazini lakho. |
| Ukuba uneengxaki zokujikeleza kwegazi emilenzeni. |
| Ukuba isisu sisusiwe ngokupheleleyo ngotyando (iTotal Gastrectomy). |
| Ukuba une-allergy kwi-nilotinib, i-lactose, i-gelatin, okanye naluphi na olunye unyango okanye ukutya. |
| Ukuba ukhulelwe, uzama ukukhulelwa, okanye uncancisa. |
Ndingayisebenzisa njani kanye kanye le yeza?
Ukuze ufumane okuninzi kweli yeza, kubaluleke kakhulu ukulisebenzisa ngokuchanekileyo.
- Yisele ungenanto esiswini: Le yeyona nto ibalulekileyo. Ufanele uyisele iyeza ubuncinane iyure enye ngaphambi okanye iiyure ezimbini emva kokutya. Ukusela eli yeza kunye nokutya kunokutshintsha ubungakanani bomzimba obufunxwayo kwaye kubangele iziphumo ebezingalindelekanga eziyingozi.
- Sela neglasi yamanzi: Ginya ikhaphu yonke ngeglasi yamanzi.
- Musa ukuphula, ukutyumza, okanye ukuhlafuna ikhaphu: Musa ukuphula, ukutyumza, okanye ukuhlafuna ikhaphu.
- Ukuba unengxaki yokuginya: Abanye abantu banengxaki yokuginya iikhaphu. Ukuba kunjalo, ungakhathazeki. Vula ikhaphu ngononophelo, xuba umgubo nethisipuni ye-applesauce, uze uginye umxube ngoko nangoko . Musa ukuwugcina ukuze usetyenziswe kamva.
- Ziphephe iigrapefruit: Musa ukusela ijusi yeegrapefruit okanye utye iigrapefruit nangasiphi na isizathu. Oku kungayitshintsha ngendlela eyingozi indlela elisebenza ngayo iyeza.
- Ixesha lokuthatha kunye namanye amayeza: Ukuba uthatha amayeza e-gastritis, musa ukuthatha amayeza afana ne-antacids (umz., iDigene) kwiiyure ezi-2 ngaphambi okanye emva kokuthatha le capsule. Thatha amayeza afana ne-H2-blockers (umz., iFamotidine) kwiiyure ezili-10 ngaphambi okanye kwiiyure ezi-2 emva kokuthatha le mayeza. Cela ugqirha wakho ukuba akuqinisekise oku.
- Yithathe ngexesha: Zama ukusela amayeza akho ngexesha elifanayo yonke imihla. Musa ukuyeka ukuwasela amayeza akho ngaphandle kwengcebiso kagqirha wakho.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Ukuba uphoswe yidosi, ungaze uyiphinde kabini idosi elandelayo ukuze uyibuyisele. Oko kunokuba yingozi. Libala ngedosi oyiphosileyo kwaye uthathe idosi emiselweyo kuphela ngexesha elilandelayo elicwangcisiweyo.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Ukuba ngempazamo uthatha ngaphezu kwedosi emiselweyo, yingxamiseko. Fowunela iZiko loLwazi lweePoisons kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko , okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Amanye amayeza anokusebenzisana neNilotinib
I-Nilotinib liyeza elinamandla amakhulu okusebenzisana namanye amayeza. Ngoko ke, kubalulekile ukuxelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo.
| Musa ukuthatha iNilotinib kunye nale yeza. |
|---|
| ICisapride, iDronedarone, iPimozide, iThioridazine, iZiprasidone (amayeza achaphazela izinga lentliziyo) |
| I-Flibanserin, iLomitapide, iSaquinavir |
| I-Fluconazole, iPosaconazole (iyeza lokulwa nefungus) |
| Ukuba usebenzisa ezi zinto, yazisa ugqirha wakho. |
|---|
| Amayeza okulwa nentsholongwane kaGawulayo/uGawulayo |
| Ii-antibiotics ezifana neClarithromycin kunye ne-Erythromycin |
| Amayeza oxinzelelo lwegazi oluphezulu, isifo sentliziyo, kunye nesifo sengqondo |
| Ezinye izinto ezibulala iintsholongwane ezifana neKetoconazole, iItraconazole |
| Amayeza okunyanga isifo se-gastritis (i-Antacids, i-Cimetidine, i-Omeprazole) |
| Izinto zokunciphisa igazi ezifana neWarfarin |
| Iimveliso zezityalo ezifana neSt. John's Wort |
Akukho nanye kwezi luhlu ipheleleyo. Ngoko ke, kubalulekile ukuxelela ugqirha wakho malunga nawo onke amayeza, iivithamini, iimveliso zezityalo, kunye namayeza esintu owasebenzisayo.
Zithini iziphumo ebezingalindelekanga ezinokubakho xa usebenzisa amayeza?
Njengayo nayiphi na imithi, iNilotinib inokubangela iziphumo ebezingalindelekanga. Ezinye zinzima, ngelixa ezinye zixhaphakile. Into ebalulekileyo kukwazi ezi zinto kwaye uthathe amanyathelo ngokukhawuleza ukuba kuyimfuneko.
| Imiphumela | Iimpawu onokuzilindela |
|---|---|
| Iziphumo ebezingalindelekanga ezifuna unyango olukhawulezileyo | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Ukopha | Indle emnyama okanye enegazi, ukuhlanza okufana nekofu egayiweyo, amabala abomvu eluswini, ukopha okungaqhelekanga okuvela empumlweni okanye kwiintsini. |
| Utshintsho kwisantya sentliziyo | Intlungu yesifuba, isiyezi, ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga, ukuquleka. |
| Ukulimala kwesibindi | Umchamo otyheli okanye omdaka omnyama, ukutyheli kwamehlo okanye ulusu, iintlungu kwinxalenye ephezulu ngasekunene yesisu, ukungabi namdla wokutya. |
| I-Pancreatitis | Intlungu yesisu (ingakumbi ephuma emqolo), intlungu eba mandundu emva kokutya, umkhuhlane, isicaphucaphu, ukuhlanza. |
| Ukuqokelelana kolwelo emzimbeni (i-Edema) | Ukutyeba ngequbuliso, ukudumba kwamaqatha, amalungu, ubunzima bokuphefumla. |
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Iingxaki eziqhelekileyo | Intloko ebuhlungu, isicaphucaphu, ukuhlanza, urhudo, ukuqhina kwesisu. |
Lumka ngakumbi ngexesha lokukhulelwa kunye nokuncancisa
Le yingongoma ebaluleke kakhulu.
- Ungaze ukhulelwe ngelixa uthatha iNilotinib.
- Kuphephe ukukhulelwa ubuncinane iintsuku ezili-14 emva kokuyeka ukusebenzisa amayeza.
- Musa ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza kwaye emva kweentsuku ezili-14 emva kokuba uyekile.
Eli yeza linokubangela ingozi enkulu kumntwana ongekazalwa, ngoko ke thetha nogqirha wakho ngale nto ngokukhululekileyo.
Umyalezo Wokuya Ekhaya
- Soloko usela iNilotinib ungenanto esiswini, nokuba yiyure enye ngaphambi kokutya okanye iiyure ezimbini emva kokutya.
- Ungaze utye igrapefruit okanye usele ijusi yayo.
- Qiniseka ukuba uxelela ugqirha wakho ngazo zonke ezinye iziyobisi, iivithamini, kunye neemveliso zezityalo ozisebenzisayo.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezinzulu ezifana neentlungu zesifuba, ubunzima bokuphefumla, okanye ukopha okungaqhelekanga, funa ingcebiso kagqirha ngokukhawuleza.
- Kuphephe ukukhulelwa nokuncancisa ngokupheleleyo xa usebenzisa amayeza kwaye emva kweentsuku ezili-14 uyekile.
- Musa ukulibazisa ixesha lakho lokuya ekliniki nogqirha. Yenza uvavanyo lwegazi lakho njengoko kucwangcisiwe.
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