Ngaba ugqirha wakho ukunike iPanobinostat okanye umntu omaziyo? Liyeza elinzima, kodwa elibaluleke kakhulu, elisetyenziselwa ukunyanga umhlaza. Ngoko ke namhlanje, masithethe ngokufutshane ngeli yeza, imiphumo yalo emzimbeni, kunye nezinto ekufuneka uziqaphele xa ulisebenzisa. Ukwazi ezi zinto kubaluleke kakhulu kukhuseleko lwakho kunye nempumelelo yonyango lwakho.
Yintoni iPanobinostat?
Ngamafutshane, iPanobinostat liyeza le-chemotherapy elijolise kwiiseli zomhlaza. Lisetyenziswa ngokukodwa ukunyanga imeko yomhlaza ebizwa ngokuba yi-multiple myeloma .
Khawuthelekelele ukuba iseli yomhlaza ifuna 'iproteni' ethile ukuze ikhule kwaye yahlulwe. Okwenziwa leli yeza kukujolisa loo protein ethile kwaye iyeke ukusebenza kwayo. Ukuchaneka, kufana nokucima 'injini' ekufuneka iseli yomhlaza ikhule. Ngale ndlela, ukulawula ukukhula nokusasazeka kweeseli zomhlaza ngumsebenzi ophambili wale yeza.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza
Kubalulekile ukuba ugqirha wakho ayazi imbali yakho epheleleyo yempilo ngaphambi kokuba aqalise eli yeza. Ngoko ke, ukuba unayo nayiphi na kwezi zilandelayo, qiniseka ukuba uyayikhankanya .
- Ukuba unesifo sokopha .
- Ukuba unesifo sorhudo rhoqo.
- Ukuba unesifo sentliziyo okanye ukuba kukho umntu kusapho lwakho onaso.
- Ukuba ngaphambili ukhe wehla kwiiseli zegazi ezibomvu okanye ezimhlophe ngenxa yeyeza.
- Ukuba okwangoku unentsholongwane .
- Ukuba unesifo sesibindi .
- Ukuba iimvavanyo zifumanise ukuba inqanaba le-potassium okanye i-magnesium egazini liphantsi .
- Ukuba une -allergy kwi-Panobinostat okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukuba ukhulelwe, uzama ukukhulelwa, okanye uncancisa .
Musa ukuyifihla le ngcaciso kugqirha wakho, kuba konke oku kubaluleke kakhulu kukhuseleko lwakho nakwimpumelelo yonyango lwakho.
Ulisebenzisa njani kanye kanye eli yeza?
Kubaluleke kakhulu ukulandela imiyalelo echanekileyo yokusebenzisa eli yeza.
- Indlela yokuthatha: Eli yeza liza likwimo yekhaphu. Liginye liphelele ngeglasi yamanzi. Ungaze uliqhekeze, ulityumze, okanye ulihlafune ikhaphu.
- Ukuthabatha nokutya:Ungalithatha eli yeza nokuba utya okanye ungenalo. Kodwa eyona nto ibalulekileyo kukulithatha ngendlela efanayo yonke imihla . Umzekelo, ukuba ulithatha emva kokutya yonke imihla, qhubeka ulithatha ngaloo ndlela.
- Izinto ekufuneka uziphephe: Le yeyona nto ibalulekileyo. Musa ukusela iziqhamo zeenkwenkwezi, ijusi yepomegranate, okanye ijusi yegrapefruit ngelixa usela eli yeza. Oku kutya kunokuchaphazela kakhulu ukusebenza kweyeza.
- Ukuba uphoswe yidosi: Ukuba ulibele ukusela idosi, yisele kwangoko xa ukhumbula. Nangona kunjalo, ukuba kungaphantsi kweeyure ezili-12 ngaphambi kwedosi yakho elandelayo, yitsibe idosi oyiphosileyo uze uthathe idosi yakho elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye.
- Ukuba uyahlanza: Ukuba uyahlanza emva kokusela iyeza, musa ukuthatha elinye idosi ngaloo mini. Thatha iyeza njengesiqhelo ngexesha elicwangcisiweyo ngosuku olulandelayo.
- Ukuba uthatha amayeza amaninzi kakhulu: Ukuba ucinga ukuba uthathe amayeza amaninzi kakhulu, fowunela iZiko loLwazi lweePoisons kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko, okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Izinto ezikhethekileyo ekufuneka uziqaphele xa usebenzisa amayeza
Ukuzikhusela komzimba kunye nosulelo
Eli yeza linokuthoba amandla omzimba wakho okuzikhusela . Oku kuthetha ukuba usenokuba sesichengeni ngakumbi sokufumana izifo, ingakumbi izifo. Ke ngoko, ukuba ufumana iimpawu ezinje ngomkhuhlane, umkhuhlane, umphimbo obuhlungu, okanye ukukhwehlela, musa ukuzinyanga kwaye uxelele ugqirha wakho ngoko nangoko. Kungcono ukuzama ukuhlala kude nabantu abagulayo kangangoko kunokwenzeka.
Ukukhulelwa nokuzala umntwana
Le yingxaki ebaluleke kakhulu.
- Kwabasetyhini: Kuphephe ukukhulelwa ngokupheleleyo ngelixa usebenzisa eli yeza kwaye emva kweenyanga ezi-3 emva kokuyeka unyango.
- Kwamadoda: Ukuba usela eli yeza, kuphephe ukuba nguyise womntwana ngexesha lonyango kwaye kangangeenyanga ezi-6 emva kokuyeka unyango.
- Eli yeza linokulimaza kakhulu usana olungekazalwa. Kwakhona, musa ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza.
- Eli yeza lisenokuchaphazela ukuzala. Ukuba uneengxaki malunga noku, thetha nogqirha wakho ngaphambi kokuba uqale unyango.
Ezinye iziphumo
Xelela ugqirha wakho ukuba unesifo sorhudo esigqithisileyo, ukuhlanza, okanye ukubila. Ukuphelelwa ngamanzi emzimbeni kunokubangela ezinye iingxaki. Kuya kufuneka uvavanywe igazi rhoqo ngelixa usebenzisa eli yeza.
Iziphumo ebezingalindelekanga kunye nokusebenzisana kwale mithi
I-Panobinostat liyeza elinokusebenzisana namanye amayeza amaninzi, ngoko ke kubaluleke kakhulu ukuxelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo (kuquka iivithamini, amayeza emifuno, kunye nezongezo).
| Uhlobo lwesiphumo esibi | Iimpawu kunye neenkcukacha |
|---|---|
| Iziphumo ebezingalindelekanga ezifuna unyango olukhawulezileyo | |
| Iimpendulo ze-Allergic | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Utshintsho kwisantya sentliziyo | Intlungu yesifuba, isiyezi, ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga, ukuquleka, ubunzima bokuphefumla. Le meko ibizwa ngokuba yi-QT interval prolongation. |
| Ukuncipha kweeseli zegazi | Oku kwandisa umngcipheko wosulelo (umkhuhlane, ukukhohlela, umphimbo obuhlungu) kunye nokopha (amabala abomvu eluswini, ukopha empumlweni/ezintsinini). |
| Iimpawu zokopha | Indle emnyama okanye enegazi, ukuhlanza okufana nekofu egayiweyo, umchamo obomvu/omdaka omnyama. |
| Iimpawu zomonakalo wesibindi | Ukutyheli kwamehlo okanye ulusu, umchamo otyheli/omdaka omnyama, iintlungu kwicala eliphezulu lasekunene lesisu, ukungabi namdla wokutya. |
| Ezinye iimpawu ezinzulu | Urhudo olukhulu, intloko ebuhlungu, ukudideka, ubunzima bokuthetha okanye ukuqonda, ukudumba kwemilenze okanye amaqatha. |
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Iingxaki ngokubanzi | Ukungabi namdla wokutya, isicaphucaphu, ukuhlanza, kunye nokudinwa. Ezi ziqhelekile, kodwa xelela ugqirha wakho ukuba ziyaqhubeka okanye zinzima. |
Umyalezo Wokuya Ekhaya
- I-Panobinostat lunyango olujoliswe kwi-multiple myeloma. Soloko ulandela imiyalelo kagqirha wakho ngokuchanekileyo.
- Xelela ugqirha wakho ngazo zonke ezinye iziyobisi kunye neevithamini ozisebenzisayo. Ingakumbi, kuphephe ukusela ipomegranate, igrapefruit, kunye nejusi yegrapefruit ngokupheleleyo.
- Ukuba ubona naziphi na iimpawu ezinzulu ezifana nomkhuhlane, urhudo olunzima, ukopha, iintlungu zesifuba, okanye utshintsho kwintliziyo yakho, yazisa ugqirha wakho okanye isibhedlele ngoko nangoko.
- Kubaluleke kakhulu kukhuseleko lwakho nolomntwana wakho ongekazalwa ukuphepha ukukhulelwa okanye ukuba nguyise wabantwana ngelixa usebenzisa eli yeza kwaye emva kwexesha elithile.
- Gcina eli yeza kude nokufikelela kwabantwana, kwiphakheji yalo yokuqala, kwaye kude nokukhanya.
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