Kukho amayeza akhethekileyo anyanga iimeko ezibangelwa lutshintsho oluthile kwinkqubo yehomoni yomzimba wakho. Mhlawumbi ugqirha wakho ukunike elinye lala mayeza okanye umntu omaziyo. IPasireotide yenye ye-injection ekhethekileyo. Namhlanje, siza kuthetha ngale mayeza, into ayenzayo, kunye nento ekufuneka uyilumkele, ngendlela elula neyobuhlobo.
Kalula nje, yintoni iPasireotide?
I-Pasireotide liyeza elisetyenziselwa ukulawula amanqanaba eehomoni ezithile eziveliswa emizimbeni yethu. Lidla ngokunikezelwa njengenaliti. Eli yeza lisetyenziswa kakhulu kwiimeko ezimbini.
1. I-Acromegaly: Le yimeko ebangelwa kukuvelisa i-hormone yokukhula eninzi kakhulu. Oku kunokubangela ukuba amathambo ezandleni, ezinyaweni nasebusweni akhule. I-Pasireotide isebenza ngokulawula eli nqanaba le-hormone yokukhula ligqithisileyo.
2. Isifo sikaCushing: Le yimeko apho umzimba uvelisa i-hormone ethi `cortisol` eninzi. Oku kunokukhokelela kwiingxaki ezininzi ezifana nokutyeba kakhulu, uxinzelelo lwegazi oluphezulu, nesifo seswekile. I-Pasireotide inceda ukulawula esi sifo ngokunciphisa eli nqanaba le-`cortisol`.
Okubaluleke kakhulu, eli yeza lidla ngokusetyenziswa kuphela kwiimeko apho utyando lungenakwenzeka, okanye ukuba isifo asilawulwa ngokupheleleyo emva kotyando. Igama lophawu lwale nto lisenokuba yi-`(Signifor LAR)`.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale amayeza
Oku kubaluleke kakhulu. Ugqirha wakho uya kufuna ukwazi imbali yakho epheleleyo yempilo ngaphambi kokuba aqalise olu nyango, njengoko ezinye iimeko zonyango zifuna unonophelo olukhethekileyo xa usebenzisa eli yeza.
| Imeko yakho | Kutheni isaziso sibalulekile? |
|---|---|
| Isifo seswekile okanye amanqanaba aphezulu eswekile egazini | I-Pasireotide inokubangela ukuba amanqanaba eswekile egazini anyuke ngakumbi, ngoko ke utshintsho kulawulo lwesifo seswekile lunokufuneka. |
| Imbali yesifo sentliziyo okanye ukubetha kwentliziyo okungaqhelekanga | Eli yeza linokuchaphazela isingqisho sokubetha kwentliziyo, ingakumbi ukubetha kwentliziyo kunokucotha . |
| Isifo senyongo | Eli yeza linokunyusa umngcipheko wokuba ne-gallstones. |
| Isifo sesibindi | Ukuba ukusebenza kwesibindi akulunganga, idosi ingadinga ukulungiswa njengoko iyeza linokususwa emzimbeni kancinci kancinci. |
| Amanqanaba aphantsi e-magnesium okanye i-potassium egazini | Amanqanaba aphantsi ezi minerali achaphazela isantya sentliziyo, kwaye iPasireotide inokuyenza imeko ibe mandundu. |
| Ukukhulelwa, ukuzama ukukhulelwa, okanye ukuncancisa | Akukabikho datha ipheleleyo malunga nemiphumo yale yeza ngexesha lokukhulelwa kunye noomama abancancisayo. Kungoko ke, kubalulekile ukuthetha nogqirha wakho ngale nto. |
| Ukunganyamezelani kwamanye amayeza, ukutya okanye izinto | Ukuba une-allergies, kubalulekile ukujonga ukuba ingaba ibangelwa yiPasireotide. |
Inikwa kwaye isetyenziswa njani le gonyo?
Eli asiloyeza onokulithatha ekhaya. IPasireotide yinaliti efakwa ngaphantsi kwesikhumba . Idla ngokunikwa yingcali yezonyango eqeqeshiweyo (ugqirha okanye umongikazi) esibhedlele okanye eklinikhi.
Ngaphambi kokuba uqale unyango, uza kunikwa incwadana ekhethekileyo ebizwa ngokuba yi-"MedGuide" equlethe ulwazi malunga nalo nyango. Kubaluleke kakhulu ukuyifunda nokuyiqonda ngononophelo le nto ngaphambi konyango ngalunye.
Yintoni omawuyenze ukuba ugqithisile?
Oku kunikwa esibhedlele, ngoko ke amathuba okuba oko kwenzeke mancinci. Kodwa ukuba ngandlela ithile uziva ngathi usele kakhulu,Fowunela iZiko loLwazi lweTyhefu leSizwe kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko, okanye uye kwiYunithi yoNyango oluNgxamisekileyo (i-ETU) ekufutshane.
Kuthekani ukuba uphoswa lusuku omele ugonywe ngalo?
Kubaluleke kakhulu ukufumana isitofu sogonyo ngexesha lonyango. Ukuba awukwazi ukuya ngomhla omiselweyo, qiniseka ukuba ufowunela ugqirha wakho okanye ikliniki kwaye ubazise.
Ngawaphi amanye amayeza anokusebenza kunye nePasireotide?
Amanye amayeza owasebenzisayo anokusebenzisana nePasireotide aze abangele iingxaki. Ngoko ke, kufuneka uxelele ugqirha wakho ngawo onke amayeza owasebenzisayo (kuquka iivithamini, amayeza emifuno, kunye nezongezo) .
| Musa ukuthatha iPasireotide kunye nale yeza! | |
|---|---|
| I-Cisapride | I-Dronedarone |
| I-Pimozide | I-Thioridazine |
| Iingxaki zinokubakho nakule mithi (kuphela xa kucetyiswa ngugqirha) | |
| Ii-Beta-blockers (umz. i-metoprolol, i-propranolol) | Izithinteli zeCalcium channel (umz. iDiltiazem, iVerapamil) |
| I-Bromocriptine | I-Cyclosporine |
| I-Digoxin | Amanye amayeza achaphazela isigqi sentliziyo (andisa ixesha le-QT) |
Olu luhlu aluphelelanga, ngoko ke kubaluleke kakhulu ukuxelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo, nokuba uyatshaya okanye uyasela utywala.
Iziphumo ebezingalindelekanga ekufuneka uzazi xa uthatha amayeza
Njengalo naliphi na iyeza, iPasireotide inokubangela iziphumo ebezingalindelekanga. Ezinye azibi nkulu, kodwa ezinye zifuna ingqalelo ekhawulezileyo.
| Imiphumela | Inkcazo kunye nento omawuyenze |
|---|---|
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka zixelwe kugqirha ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Iingxaki zesantya sentliziyo | Ukubetha kwentliziyo okukhawulezayo okanye okungahambelaniyo, ukubetha kwentliziyo okubuhlungu, okanye ukubetha kwentliziyo okucothayo kunesiqhelo. |
| Ukuquleka / Ukuquleka | Ukuba nesiyezi, ukuziva ngathi amehlo akho ajika abe luhlaza okwesibhakabhaka, kwaye uyaphelelwa ngamandla. |
| Iimpawu zamanqanaba aphezulu eswekile egazini | Ukuziva unxaniwe ngaphezu kwesiqhelo, indlala eyongezelelekileyo, ukuchama rhoqo, ukudinwa kakhulu, ukubona izinto ezingaqhelekanga. |
| Iingxaki zesibindi okanye zenyongo | Ukutyheli kwamehlo okanye ulusu (i-jaundice), iintlungu kwicala eliphezulu lasekunene lesisu, ukungabi namdla wokutya. |
| Izinto ezingaqhelekanga ukuba zimbi, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Intlungu yesisu/urhudo | Ukudumba okanye ukungonwabi esiswini. |
| Intloko ebuhlungu | Intloko ebuhlungu eqhelekileyo. |
| Ukulahleka kweenwele | Ukulahleka kweenwele |
| Intlungu kwindawo yokutofa | Ububomvu, ukurhawuzelela, okanye intlungu kwindawo yokuhlatywa. |
Ugqirha wakho uza kukujonga kulo lonke ixesha lonyango. Kubalulekile ukuba uhlolwe igazi rhoqo . Kwakhona, ukuba iimpawu zakho aziphucuki okanye zibonakala zisiba mandundu, ungalibazisi ukuxelela ugqirha wakho.
Umyalezo Wokuya Ekhaya
- IPasireotide sisitofu sokugonya esinikwa esibhedlele ukunyanga iimeko ezithile zehomoni, ezifana ne-acromegaly kunye nesifo sikaCushing.
- Ngaphambi kokuba uqale unyango, qiniseka ukuba uxelela ugqirha wakho ngazo zonke iimeko zempilo onazo kunye nawo onke amayeza owasebenzisayo.
- Ngelixa usebenzisa eli yeza, qaphela izinto ezifana namanqanaba aphezulu eswekile egazini, utshintsho kwisantya sentliziyo, kunye neengxaki zesibindi.
- Ukuba ufumana isiphumo esibi kakhulu (umz. isiyezi esinzima, iintlungu zesifuba, ukutyheli kolusu), funa ingcebiso kagqirha ngokukhawuleza.
- Ukuya kwiikliniki kunye nokuhlolwa kwegazi ngemihla emiselweyo kubalulekile ukuze unyango luphumelele.
- Ukuba unemibuzo, iinkxalabo, okanye amathandabuzo malunga nale mithi, ungoyiki ukuthetha ngokukhululekileyo nogqirha wakho ngayo.
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