Nawe ukhe wafakelwa isitho somzimba, njengesintso, isibindi, okanye intliziyo, waza ugqirha wakunika iyeza elikhethekileyo lokuthintela ukuba isitho esitsha singaliwa ngumzimba wakho. Uninzi lwexesha, elo yeza libizwa ngokuba yiTacrolimus. Eli liyeza elibaluleke kakhulu, kwaye liyeza elifanele lisetyenziswe ngononophelo. Ngoko ke, njengomhlobo wakho, ndilapha ukukuxelela yonke into omawuyazi malunga neli yeza ngolwimi olulula noluqondakalayo lwesiSinhala.
Ngamafutshane, yintoni iTacrolimus?
Cinga ngenkqubo yomzimba wethu yokuzikhusela njengomkhosi okhusela ilizwe. Lo mkhosi utshabalalisa iintshaba ezifana neentsholongwane kunye neentsholongwane ezivela ngaphandle. Ngoku, xa ufumana utyando olutsha lwesitho, lo "mkhosi" emzimbeni wethu ubona elo lungu litsha "njengotshaba." Kuba yinto entsha emzimbeni. Ngoko ke lo mkhosi uqala ukuhlasela isitho esitsha. Oku sikubiza ngokuba "kukugatywa kwesitho."
I -Tacrolimus liyeza elithomalalisa umsebenzi waloo "mkhosi." Kwizonyango, sizibiza ezi zinto ngokuthi zi-immunosuppressants . Ngamafutshane, eli yeza lixelela inkqubo yethu yomzimba ukuba, "Musani ukukhathazeka, eli lungu litsha ngumhlobo wethu, musani ukulihlasela." Ngoko ke ilungu elitsha elisandul' ukufakelwa liqala ukusebenza njengenxalenye yomzimba wakho ngaphandle kweengxaki.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale eli yeza
Kubaluleke kakhulu ukuba ugqirha wakho azi kakuhle imeko yakho yempilo ngaphambi kokuba akunike eli yeza. Ngoko ke, ukuba unenye yezi meko zidweliswe ngezantsi, qiniseka ukuba uyamxelela ugqirha wakho.
- Ukuba unesifo seswekile .
- Ukuba unesifo sentliziyo .
- Ukuba une- high blood pressure .
- Ukuba kukho enye ingxaki ngenkqubo yomzimba yokuzikhusela.
- Ukuba unesifo esikhoyo (nokuba yinto efana nomkhuhlane, umkhuhlane, ukukhwehlela).
- Ukuba unesifo sezintso .
- Ukuba unesifo sesibindi .
- Ukuba ucwangciselwe ukufumana isitofu sokugonya kwixesha elizayo okanye usandul' ukusifumana.
- Ukuba ukhe waba ne-allergy kwi-tacrolimus okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukuba uzama ukukhulelwa okanye ukhulelwe .
- Ukuba ungumama oncancisayo .
Kubaluleke kakhulu kukhuseleko lwakho ukuthetha ezi zinto ngaphandle kokuzifihla.
Yeyiphi indlela echanekileyo yokusela amayeza?
Ukuze ufumane okuninzi kweli yeza, kufuneka ulithathe kanye njengoko kuyalelwe.
- Ginya iyeza lonke ngeglasi yamanzi.
- Musa ukulisebenzisa eli yeza kunye nejusi yegrapefruit okanye yegrapefruit nangasiphi na isizathu. Oku kubaluleke kakhulu. Ijusi yegrapefruit inokubangela amanqanaba aphezulu eTacrolimus emzimbeni.
- Ziqhelise ukusela amayeza akho ngexesha elifanayo yonke imihla. Ukuba yintsimbi yesi-8 kusasa, thatha ngentsimbi yesi-8 kusasa yonke imihla. Oku kuya kunceda ukugcina amanqanaba amayeza emzimbeni wakho ehambelana.
- Musa ukuphula, ukutyumza, okanye ukuhlafuna iyeza. Liginye lonke.
- Ungalithatha eli yeza ngaphambi okanye emva kokutya. Nangona kunjalo, kufuneka uziqhelise ukulithatha ngexesha elifanayo yonke imihla. Ukuba ulithatha ngaphambi kokutya, lithathe yonke imihla ngaphambi kokutya. Ukuba ulithatha emva kokutya, lithathe yonke imihla emva kokutya.
- Qhubeka usebenzisa eli yeza de ugqirha wakho akuxelele ukuba uyeke. Musa ukuyeka ngequbuliso.
Khumbula, eli yeza limiselwe wena wedwa. Ungaze unike omnye umntu iyeza lakho, nokuba uneempawu ezifanayo nezakho.
Ungenza ntoni ukuba uthatha amayeza amaninzi kakhulu?
Ukuba ucinga ukuba uthathe amayeza amaninzi kunedosi emiselweyo, ungoyiki kwaye thatha inyathelo ngoko nangoko.
- Ukuba kunokwenzeka, yiya kwiSebe lezeMpilo eziNgxamisekileyo (ETU) lesibhedlele esikufutshane ngoko nangoko.
- Okanye, fowunela iZiko loLwazi ngeTyhefu leSizwe kwiSibhedlele sikaZwelonke saseColombo ukuze ufumane ingcebiso.
Kuthekani ukuba ndilibele ukusela amayeza am?
Sonke siyalibala izinto. Ukuba ulibele ukusela amayeza akho, nantsi into omawuyenze:
- Thatha idosi oyiphosileyo ngokukhawuleza nje ukuba uyakhumbula.
- Nangona kunjalo, ukuba sele kusondele ixesha lokusebenzisa idosi yakho elandelayo xa ukhumbula (umz., kusele iiyure ezimbalwa kuphela), yeka idosi oyiphosileyo uze uthathe idosi yakho elandelayo ngexesha elicwangcisiweyo.
- Ungaze uthathe idosi ephindwe kabini ukuze uhlawule idosi ephosiweyo kunye nedosi elandelayo.
Amanye amayeza anokusebenzisana neTacrolimus
I-Tacrolimus inokusebenzisana namanye amayeza amaninzi. Ngoko ke, xelela ugqirha wakho ngawo onke amayeza owasebenzisayo (amayeza kagqirha, amayeza okuphelisa iintlungu athengiswa ngaphandle kwemvume kagqirha, iivithamini, amayeza emifuno, kunye nezongezo zemifuno, ezifana ne-St. John's wort). Ungafumana ulwazi oluthe kratya malunga noku kwitheyibhile engezantsi.
| Uhlobo lwamayeza/lokutya | Amanqaku akhethekileyo |
|---|---|
| Ungaze uzithathe ezi neTacrolimus! | |
| I-Grapefruit kunye nejusi yayo | Iyanyusa ngokuyingozi inqanaba leTacrolimus emzimbeni. |
| I-Cyclosporine | Ukusela la mayeza mabini kunye kunokonakalisa izintso. |
| Izitofu zokugonya iintsholongwane eziphilayo | Ngenxa yokungabikho komzimba oqinileyo, isitofu sokugonya sinokubangela ukugula. |
| Amayeza afana neFluconazole, iKetoconazole, iCidofovir, iDronedarone, iPimozide | Ezi zinokuchaphazela kakhulu amanqanaba eTacrolimus. |
| Ukuba uthatha ezi, qiniseka ukuba uxelele ugqirha wakho. | |
| Amanye amayeza okubulala iintsholongwane | Umzekelo: iClarithromycin, iRifampin |
| Amayeza oxinzelelo lwegazi nesifo sentliziyo | Umzekelo: Diltiazem, Enalapril, Losartan |
| Izinto ezilwa nokungunda | Umzekelo: Itraconazole, iVoriconazole |
| I-wort yaseSt. John | Oku kunciphisa ukusebenza kakuhle kweTacrolimus. |
| Ii-antivirals ze-HIV okanye i-Hepatitis | Ezi zinokuchaphazela amanqanaba eTacrolimus. |
Izinto ekufuneka uzilumkele ngakumbi xa usebenzisa eli yeza:
Kuya kufuneka wenze utshintsho oluncinci kwindlela ophila ngayo ngelixa usela i-tacrolimus. Ezi zibaluleke kakhulu kukhuseleko lwakho.
Uvavanyo lwezonyango olucwangcisiweyo
Ugqirha wakho kuya kufuneka akubone rhoqo. Uza kuyalela novavanyo lwegazi rhoqo ukujonga amanqanaba akho eTacrolimus kunye nokusebenza kwezintso. Ungaze uphoswe zezi zihlandlo zovavanyo lwegazi.
Zikhusele kwiintsholongwane
Ngenxa yokuba eli yeza linciphisa ukusebenza kwenkqubo yakho yokuzikhusela komzimba, unamathuba amaninzi okufumana izifo, ingakumbi izifo.
- Nciphisa ukuya kwiindawo ezinabantu abaninzi kangangoko unako.
- Hlala kude nabantu abanezifo ezifana nomkhuhlane kunye nomkhuhlane.
- Hlamba izandla zakho rhoqo ngesepha.
- Ukuba ubonakalisa iimpawu zosulelo olufana nomkhuhlane, ukubanda, umphimbo obuhlungu, ukukhwehlela, okanye ukutshisa xa uchama, musa ukuzinyanga kwaye utsalele ugqirha wakho umnxeba ngoko nangoko.
Ukukhulelwa kunye nolawulo lokuzalwa
- Abafazi: Ukukhulelwa ngelixa usebenzisa la mayeza kunokubangela iziphene ezinkulu zokuzalwa komntwana. Kungoko ke, kubalulekile ukusebenzisa iindlela zokulawula ukuzalwa ezithembekileyo ngaphambi kokuba uqale ukusebenzisa la mayeza kwaye ngalo lonke ixesha uwasebenzisa. Thetha nogqirha wakho ngale nto.
- Amadoda: Ukuba usela eli yeza, kubalulekile ukusebenzisa ikhondom ngexesha lokwabelana ngesondo. Ukuba iqabane lakho liyakhulelwa, yazisa ugqirha wakho ngoko nangoko.
Lumka ilanga.
I-Tacrolimus inokwenza ulusu lwakho lube buthathaka ngakumbi elangeni kwaye inokunyusa kancinci umngcipheko wakho wokuba nomhlaza wolusu.
- Kuphephe ukuphuma elangeni kangangoko unako.
- Ukuba uphuma elangeni, nxiba impahla enemikhono emide, umnqwazi, kwaye usebenzise i -sunscreen efanelekileyo.
Inqanaba leswekile egazini
Eli yeza linokubangela amanqanaba aphezulu eswekile egazini (i-hyperglycemia) . Lo mngcipheko uphezulu kakhulu ukuba unesifo seswekile. Lumka kwiimpawu ezinje ngokunxanwa rhoqo, ukuchama rhoqo, kunye nokungaboni kakuhle.
Iziphumo ebezingalindelekanga ezinokubakho ngenxa yamayeza
Njengalo naliphi na iyeza, iTacrolimus inokubangela iziphumo ebezingalindelekanga. Ezinye zinzima, ngelixa ezinye zincinci. Into ebalulekileyo kukwazi ezi mpawu kwaye uthathe amanyathelo ngokukhawuleza ukuba kuyimfuneko.
| Iimpawu zeziphumo ebezingalindelekanga | Inkcazo kunye nento omawuyenze |
|---|---|
| Ukuba ufumana ezi mpawu, xelela ugqirha wakho ngoko nangoko! | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi okanye umqala. |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, umphimbo obuhlungu, amanxeba angapholiyo. |
| Ukulimala kwezintso | Ukuncipha kokuphuma komchamo, ukudumba kwamaqatha, izandla, okanye iinyawo. |
| Uxinzelelo lwegazi olunyukileyo | Intloko ebuhlungu kakhulu, isiyezi. |
| Ukwanda kweswekile egazini (i-Hyperglycemia) | Unxano olugqithisileyo, ukuchama rhoqo, ukudinwa kakhulu, ukubona izinto ezingaqhelekanga. |
| Utshintsho kwisantya sentliziyo | Ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga, isiyezi, iintlungu zesifuba. |
| Iingxaki zenkqubo yemithambo-luvo (PRES) | Intloko ebuhlungu ngequbuliso, ukudideka, utshintsho embonweni, ukuxhuzula. |
| Iziphumo kwiiseli zegazi (TTP/HUS) | Amabala amfusa eluswini okanye ngaphakathi emlonyeni, ulusu oluphaphathekileyo, ukutyheli kwamehlo, ukudinwa kakhulu, umkhuhlane. |
| Ezi zihlandlo azibalulekanga kangako, kodwa ukuba ziyaqhubeka, xelela ugqirha wakho. | |
| Urhudo okanye ukuqhina | Ezi zifo zihlala ziphela emva kweentsuku ezimbalwa. |
| Iingxolo | Usenokuva ukungcangcazela, ingakumbi ezandleni. |
| Ingxaki yokulala | Kunokubakho ubunzima bokulala. |
| Ukungaziva mnandi okanye iintlungu ezinyaweni | Usenokuziva urhawuzelelwa zizandla neenyawo zakho. |
Ugcina kwaye ulahla njani amayeza ngokufanelekileyo?
- Gcina amayeza kude nabantwana kunye nezilwanyana zasekhaya .
- Gcina kubushushu obuqhelekileyo begumbi (phakathi kwama-20-25 degrees Celsius). Musa ukugcina kwiindawo ezinomswakama ophezulu ezifana negumbi lokuhlambela.
- Musa ukusebenzisa amayeza aphelelwe lixesha.
- Ukuze ulahle amayeza angasetyenziswanga okanye aphelelwe lixesha, kungcono uwanike esibhedlele okanye kwikhemesti. Ukuba oko akunakwenzeka, susa iikhaphu zamayeza kwisitya, uzixube nento efana nekofu egayiweyo, umhlaba, okanye inkunkuma yekati esetyenzisiweyo, uzibeke kwibhegi evalwe kakuhle, uze uzilahle enkunkuma.
Umyalezo Wokuya Ekhaya
- I-Tacrolimus liyeza elibaluleke kakhulu elikhusela amalungu omzimba wakho amatsha. Lithathe kanye njengoko ugqirha wakho ekuxelela, ngexesha elifanelekileyo, ngedosi efanelekileyo.
- Musa ukulisebenzisa eli yeza kunye nejusi yegrapefruit nangasiphi na isizathu.
- Yazisa ugqirha wakho malunga nazo zonke ezinye iziyobisi ozisebenzisayo (kuquka iivithamini kunye namayeza e-Ayurvedic).
- Ekubeni amasosha omzimba wakho esezantsi, zikhusele kwiintsholongwane. Ukuba ubonakalisa iimpawu ezifana nomkhuhlane nokukhwehlela, xelela ugqirha wakho ngoko nangoko.
- Qaphela iimpawu zeziphumo ebezingalindelekanga ezinzulu (intloko ebuhlungu, ukudumba, ubunzima bokuphefumla). Ukuba ucinga ukuba kukho into engalunganga, tsalela umnxeba ugqirha wakho.
- Kunyanzelekile ukuba uye kwiindibano zikagqirha kunye novavanyo lwegazi ngemihla emiselweyo.
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