Igama elithi umhlaza lizisa uloyiko olukhulu kuninzi lwethu. Ngoko ke, xa ugqirha ekuxelela ukuba okanye umntu omthandayo unomhlaza webele, ndiyazi ukuba kunzima ukuchaza indlela ovakalelwa ngayo. Kodwa awuwedwa kolu hambo. Ngenxa yokuqhubela phambili kwezonyango namhlanje, kukho unyango oluninzi oluhle lokulwa nomhlaza. Ngoko ke, ukuba nolwazi olufanelekileyo malunga nonyango kuya kukunika amandla amakhulu engqondweni yakho. Namhlanje, siza kuthetha ngeyeza elibaluleke kakhulu elisetyenziswa kunyango lomhlaza webele. Leyo yindibaniselwano yeenaliti ezibizwa ngokuba yiTrastuzumab kunye neHyaluronidase.
Yintoni le nto yokugonyela iTrastuzumab kunye neHyaluronidase?
Ngamafutshane, le yindibaniselwano yamayeza amabini. Xa edibene, alwa neeseli zomhlaza. Makhe sijonge ukuba la mayeza mabini enza ntoni ngokwahlukeneyo.
1. I-Trastuzumab
Le yeyona ngcali iphambili yolu nyango. I-Trastuzumab lunyango olujoliswe kulo . Oko kuthetha ukuba eli yeza alihlaseli nje kuphela zonke iiseli emzimbeni. Likhangela ngokukodwa iiseli zomhlaza kwaye lizihlasele.
Cinga ngeeseli zomhlaza njengeqela leengcango ezimbi. Ezinye iiseli zomhlaza webele zineproteni ekhethekileyo (iproteni ebizwa ngokuba yiHER2) kumphezulu wazo enceda ezo seli zahlukane kwaye zikhule ngokukhawuleza. Oku kufana nesitshixo esikhethekileyo esitshixelwe kwezo ngcango zimbi. Ukuba unaso esi sitshixo, ucango luyavuleka, kwaye iiseli zomhlaza zahlukane ngokukhawuleza.
I-Trastuzumab isebenza njengokufaka into emngxunyeni wesitshixo ize iyivale. Emva koko iiseli zomhlaza azifumani mqondiso ozenza zikhule. Ngoko ke iiseli zomhlaza ziyayeka ukwahlukana nokusasazeka okanye zigule kakhulu. Eli yeza likwiqela elibizwa ngokuba yi-"monoclonal antibody". Oko kuthetha ukuba yiproteni eyenziwe kwilebhu ngokukodwa ukujolisa kwiiseli zomhlaza, njengeenxalenye zenkqubo yomzimba wethu yokuzikhusela.
2. I-Hyaluronidase
Lo ngumxhasi weqhawe eliphambili. Asiyifaki ngqo le gonyo emthanjeni, kodwa siyifaka phantsi kwesikhumba. Emva koko imolekyuli enkulu yeproteni ebizwa ngokuba yiTrastuzumab ifuna uncedo oluncinci ukuze ifunxwe kakuhle ngumzimba.
Eli yeza, elibizwa ngokuba yiHyaluronidase, likhulula okwethutyana izicubu ezingaphantsi kolusu apho kujojozwa khona. Oku kuvumela iTrastuzumab ukuba idlule kuyo ngokulula, ingene egazini, kwaye ifikelele ngokukhawuleza kwiiseli zomhlaza apho kufuneka isebenze khona. Kufana nokucoca iimoto endleleni nokuvumela i-ambulensi ukuba ifike apho.
Eli yeza lidla ngokuthengiswa phantsi kwegama lebhrendi elithi HERCEPTIN HYLECTA .
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale eli yeza
Ngaphambi kokuba uqale naluphi na unyango, kubaluleke kakhulu ukuxelela ugqirha wakho imbali yakho epheleleyo yempilo. Kuba olo lwazi luya kumisela unyango olukhuselekileyo nolungcono kuwe. Kwimeko yale yeza, kubalulekile ukubalisa ezi zinto zilandelayo.
| Imeko yakho yempilo | Kutheni kubalulekile ukwazisa ngayo? |
|---|---|
| Isifo sentliziyo okanye ukungaphumeleli kwentliziyo | I-Trastuzumab ngamanye amaxesha inokuchaphazela ukusebenza kwentliziyo, ngoko ke ugqirha wakho uya kuqaphela ngakumbi ukuba unesifo sentliziyo esele sikhona. |
| Isifo semiphunga | Eli yeza ngamanye amaxesha linokubangela ubunzima bokuphefumla, ngoko ke kubalulekile ukwazisa ugqirha wakho kwangaphambili ukuba unesifo semiphunga esifana ne-asthma. |
| Iintlobo ngeentlobo zee-allergies (ii-Allergies) | Qiniseka ukuba uyasixelela ukuba unayo nayiphi na i-allergies kwiTrastuzumab, amanye amayeza, ukutya, okanye iidayi. |
| Ukuba uzama ukukhulelwa okanye ukhulelwe | Eli yeza linokuba yingozi kakhulu kumntwana osesiswini, ngoko ke kufuneka uqiniseke ukuba awukhulelwanga ngaphambi kokuba uqale unyango. |
| Ukuba umntwana uncanciswa | Eli yeza linokudluliselwa ebantwaneni ngobisi lwebele. Ngoko ke, ukuncancisa kufuneka kuphetshwe ngexesha nangexesha elithile emva konyango. |
Uza kunikwa njani olu nyango?
Eli asiloyeza onokulithatha ekhaya. Eli gonyo linikwa esibhedlele okanye ekliniki ngabasebenzi bezonyango abaqeqeshiweyo.
Isitofu sokugonya sinikwa phantsi kolusu lwakho (inaliti engaphantsi kwesikhumba).Ngokuqhelekileyo ifakwa kwindawo yethanga. Le nkqubo ithatha imizuzu embalwa.
Kubalulekile: Eli yeza alivumelekanga ukusetyenziswa ebantwaneni. Kwakhona, eli yeza limiselwe wena kuphela. Musa ukwabelana ngalo nabanye abantu nangasiphi na isizathu.
Kuthekani ukuba idosi yeyeza iyanda?
Oku kunikwa esibhedlele ngoko ke amathuba okuba oku kwenzeke mancinci kakhulu. Nangona kunjalo, ukuba ucinga ukuba usele amayeza amaninzi kakhulu, yazisa abasebenzi bezonyango ngoko nangoko. Ngaphandle koko, fowunela iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke , okanye uye kwiSebe leNgxamiseko (ETU) lesibhedlele esikufutshane.
Wenza ntoni ukuba uphoswe yidosi yeyeza?
Kubaluleke kakhulu ukuba olu nyango luphumelele ukusela amayeza ngomhla nexesha elicwangcisiweyo. Ukuba awukwazi ukuya esibhedlele/eklinikhi ngomhla ocwangcisiweyo, fowunela ugqirha wakho okanye eklinikhi ngoko nangoko ubazise. Baza kukuxelela into omawuyenze ngokulandelayo. Ungaze utshintshe umhla ngokwakho.
Amanye amayeza anokusebenza kunye nale mayeza
Ezinye iintlobo ze-chemotherapy, ingakumbi i-daunorubicin, i-doxorubicin, i-epirubicin, kunye ne-idarubicin, zinokunyusa umngcipheko weengxaki zentliziyo xa zisetyenziswa kunye.
Kodwa khumbula, olu luhlu aluphelelanga. Ngoko ke kubalulekile ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo, kuquka iivithamini, amayeza esintu, kunye nezongezo. Kwakhona xelela ugqirha wakho ukuba uyatshaya okanye usela utywala.
Izinto ekufuneka uzilumkele ngakumbi ngexesha lonyango
Kubalulekile ukuba unikele ingqalelo engakumbi emzimbeni wakho ngeli xesha.
Ukungonwabi kunye nempilo-ntle ngokubanzi
Kuqhelekile ukuziva udiniwe kwaye ungakhululekanga ngexesha lonyango lomhlaza, njengoko kunokuchaphazela neeseli ezisempilweni. Oku kwenzeka kubantu abaninzi. Kodwa xelela iqela lakho lezonyango ngazo naziphi na iziphumo ebezingalindelekanga ozifumanayo. Kubalulekile ukugqiba unyango, nokuba alukhululekanga, de bakuxelele ukuba uyeke.
Lumka malunga nosulelo.
Eli yeza linokwenza buthathaka amasosha omzimba wakho kancinci. Oku kuthetha ukuba unokuba sengozini yokugula kwaye ufumane usulelo. Ngoko ke, ukuba uneempawu zomkhuhlane ezifana nomkhuhlane, ukugodola, umphimbo obuhlungu, okanye ukukhwehlela , musa ukulisebenzisa njengesiqhelo . Fowunela ugqirha wakho ngoko nangoko ukuze akunike icebiso. Musa ukuphuma wedwa uyokuthatha amayeza akho. Ziphephe iindawo ezinabantu abaninzi kangangoko unako kwaye uhlale kude nabantu abagulayo.
Lumka ngeepilisi zokuthomalalisa iintlungu ezithintela umkhuhlane.
Ngaphandle kokuba ugqirha wakho ekuxelele ngokuthe ngqo, musa ukuthatha amayeza okunciphisa iintlungu afana ne-aspirin, i-acetaminophen, i-ibuprofen, okanye i-naproxen. La mayeza anokunciphisa umkhuhlane wakho. Uphawu lokuqala nolubalulekileyo losulelo ngumkhuhlane. Ukuba uyancitshiswa, usenokungazi de ube nosulelo olukhulu emzimbeni wakho.
Ukukhulelwa nokuncancisa (kubaluleke kakhulu)
Le yingxaki enkulu.
- Ukukhulelwa: Kufuneka uphephe ukukhulelwa ngelixa usebenzisa eli yeza kwaye kangangeenyanga ezisi-7 emva kokuthatha idosi yokugqibela . Eli yeza linokubangela iziphene ezinkulu zokuzalwa kusana olungekazalwa. Kuya kufuneka wenze uvavanyo lokukhulelwa ngaphambi kokuba uqale unyango. Thetha nogqirha wakho malunga nolawulo lokuzala olukulungeleyo ngeli xesha.
- Ukuncancisa: Kuphephe ukuncancisa umntwana wakho ngelixa usela amayeza kwaye kangangeenyanga ezisi-7 emva komthamo wokugqibela .
Iziphumo ebezingalindelekanga ezinokwenzeka ngeli yeza
Ezi zinto zinokuba yinto eyoyikisayo ukuva, kodwa azikho zonke ezenzeka kuye wonke umntu. Kwakhona, uninzi lwazo lunokulawulwa. Eyona nto ibalulekileyo kukwazisa iqela lakho lezonyango ukuba uvakalelwa kukuba kukho into eyahlukileyo.
| Isiphumo/impawu | Inkcazo kunye nento ekufuneka uyenze |
|---|---|
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka zixelwe kugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy okanye i-angioedema | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, amehlo, imilebe, ulwimi, izandla okanye iinyawo, ubunzima bokuginya okanye ukuphefumla. Ukuba unayo nayiphi na kwezi zinto, yingxamiseko. |
| Ubunzima bokuphefumla | Ukukhohlela okomileyo, ukuphefumla nzima, ubunzima bokuphefumla. |
| Iimpawu zokusilela kwentliziyo | Ukuphefumla nzima, ukudumba kwamaqatha, iinyawo, okanye izandla, ukunyuka kobunzima ngequbuliso, ukuziva udiniwe okanye udiniwe ngendlela engaqhelekanga. |
| Utshintsho kwisantya sentliziyo | Ukuziva ngathi intliziyo yakho ibetha ngokukhawuleza okanye ngokungacwangciswanga, isiyezi, ukuquleka, iintlungu zesifuba. |
| Igazi elonyukayo | Uxinzelelo lwakho lwegazi luya kuhlolwa rhoqo, kodwa qaphela izinto ezifana nentloko ebuhlungu kunye nesiyezi. |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, ukukhohlela, umphimbo obuhlungu. |
| Iziphumo ebezingalindelekanga eziqhelekileyo ekufuneka zixelwe kugqirha ukuba ziyaqhubeka okanye ziyakhathaza | |
| Urhudo | Sela iziselo ezifana namanzi kunye neJeevani. Ukuba ziyaqhubeka, xelela ugqirha wakho. |
| Ukulahleka kweenwele | Oku kubonakala kwiindlela ezininzi zonyango lomhlaza. Iinwele zikhula kwakhona emva kokuba unyango lugqityiwe. |
| Intloko ebuhlungu | Phumla. Sela iziselo. Xelela ugqirha wakho ukuba ziqatha okanye azipheli. |
| Intlungu yemisipha | Ukuphumla nokuhlamba umzimba ngamanzi ashushu kunokunceda. |
| Isicaphucaphu | Endaweni yokutya ukutya okukhulu ngaxeshanye, yitya ukutya okuncinci. Ugqirha uza kukunika amayeza okunyanga isicaphucaphu. |
| Ubuthathaka okanye ukudinwa okungaqhelekanga | Kuqhelekile ukuziva udiniwe ngaphezu kwesiqhelo ngeli xesha. Phumla kangangoko unako. |
Umyalezo Wokuya Ekhaya
- I-Trastuzumab kunye ne-Hyaluronidase ziindlela zonyango ezijoliswe kuzo zomhlaza wamabele ezithintela ukukhula kweeseli zomhlaza.
- Ngaphambi kokuba uqale unyango, xelela ugqirha wakho lonke ulwazi lwakho lwempilo, ingakumbi malunga nesifo sentliziyo nemiphunga.
- Olu gonyo lunikwa esibhedlele okanye ekliniki ngabasebenzi abaqeqeshiweyo. Asiloyeza elithathwa lithathwe liye ekhaya.
- Ngexesha lonyango, lumka kakhulu ngezinto ezinje ngomkhuhlane, ubunzima bokuphefumla, kunye nokudumba kwemilenze. Ukuba ubona naluphi na utshintsho, xelela ugqirha wakho ngoko nangoko.
- Kubaluleke kakhulu ukuphepha ukukhulelwa ngokupheleleyo ngelixa usela eli yeza kwaye kangangeenyanga ezisi-7 emva kokugqiba unyango.
- Ungoyiki ukuthetha neqela lakho lezonyango malunga nokungonwabi okuvayo, nokuba kuncinci kangakanani na. Basoloko bekulungele ukukunceda.
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