Ngaba wakha wavavanywa igazi ukuze kuhlolwe inqanaba le-cholesterol yakho? Ukuba ukhe wavavanywa, kufuneka ukuba uqaphele ukuba ingxelo iquka amagama anjenge-LDL, i-HDL, kunye ne-Triglycerides, kunye noonobumba be-VLDL. Sihlala sisiva nge-LDL kunye ne-HDL. Zikwabizwa ngokuba "yi-cholesterol elungileyo" kunye "ne-cholesterol embi." Kodwa yintoni i-VLDL? Eli ligama abantu abaninzi abangalaziyo. Ngoko ke ukuba ugqirha wakho uthi inqanaba lakho le-VLDL liphezulu kwingxelo yakho, kuyinto eqhelekileyo ukuziva usoyika kancinci. Kodwa ungakhathazeki. Namhlanje, kweli nqaku, siza kuthetha ngokuba yintoni kanye kanye i-VLDL, ukuba ibaluleke kangakanani emzimbeni, kwaye inokuchaphazela njani impilo yethu ukuba iyanda, kunye nendlela yokuyilawula.
Kalula nje, yintoni i-VLDL?
Intsingiselo epheleleyo ye-VLDL ithi “i-Very-Low-Density Lipoprotein”. Kulungile, ukuva eli gama kukwenze wadideka nangakumbi, akunjalo? Masiyihlalutye ngokulula size siyiqonde.
Cinga ngemithambo yegazi yethu njengeendlela. Ezi ndlela zithwala izinto ezininzi ezifunekayo emzimbeni wethu, njengezondlo kunye neoksijini. Okwangoku, amafutha emzimbeni wethu, anjenge-cholesterol kunye ne-triglycerides, nawo kufuneka athuthwe emzimbeni wonke. Kodwa kukho ingxaki. La mafutha awanakudada egazini ngokwawo, njengokuba xa wongeza ioyile emanzini, ayahlukana endaweni yokuxuba.
Ngoko ke, imizimba yethu inenkqubo ekhethekileyo "yesithuthi" yokuthutha ngokukhuselekileyo la mafutha emzimbeni wonke. Ezi zithuthi sizibiza ngokuba yi-`(Lipoprotein)`. `Lipo` ithetha amafutha, `protein` ithetha iproteni. Oko kuthetha ukuba ezi zithuthi zenziwe ngamafutha kunye neproteni.
Uyaqonda ngoku? I-VLDL sisithuthi esikhethekileyo. Esi sithuthi senziwe sisibindi sethu size sikhutshwe siye egazini. Umsebenzi ophambili we-VLDL kukuthwala ii-triglycerides kunye ne-cholesterol ukusuka esibindini ukuya kwiindawo ezahlukeneyo zomzimba, oko kukuthi, kwiindawo apho kufuneka khona amandla kunye neendawo apho kugcinwa khona amandla.
Ngoko ke i-VLDL ibalulekile ukuze imizimba yethu isebenze. Kodwa njengayo nayiphi na into, ukuba ininzi kakhulu ayilungelanga umzimba.
Yenziwe ngantoni i-VLDL particle?
Ukuba sijonga okungaphakathi kwi-VLDL ebesithethe ngayo ngaphambili, ikakhulu luhlobo lwamafutha olubizwa ngokuba yi-triglycerides. Njengokuba ibhasi inabakhweli abaninzi. Yiyo loo nto oogqirha bebiza i-VLDL ngokuba yi-"triglyceride-rich lipoprotein."
Ukongeza, kukho ezinye izinto ezimbalwa kwi-particle ye-VLDL:
- I-Cholesterol
- Amafutha e-asidi
- Uhlobo olukhethekileyo lweproteni olubizwa ngokuba yi-apolipoprotein B (i-Apolipoprotein B okanye i-apoB).
Uphando lufumanise ukuba amanqanaba aphezulu ale `(apoB)` egazini nawo angunobangela wokwanda komngcipheko wesifo sentliziyo.
Ngaba i-cholesterol ye-VLDL kunye ne-VLDL ziyafana?
Nangona sihlala sisebenzisa la magama mabini ngokutshintshana, kukho umahluko omncinci kodwa obalulekileyo phakathi kwawo omabini.
Cinga nje ngale ndlela.
- I-VLDL yibhasi. Yimoto yonke eyenziwe sisibindi kwaye ithwala amafutha.
- I-cholesterol ye-VLDL ngomnye wabakhweli kuloo bhasi. Oko kukuthi, ubungakanani be-cholesterol ehamba ngaphakathi kwisithuthi esibizwa ngokuba yi-VLDL.
Ngokufanayo, i-LDL kunye ne-HDL ziintlobo ezimbini ezahlukeneyo zeebhasi. Sibiza i-cholesterol ehamba kwibhasi ye-LDL ngokuthi yi-LDL cholesterol. Sibiza i-cholesterol ehamba kwibhasi ye-HDL ngokuthi yi-HDL cholesterol. Ngoku kucacile, akunjalo?
Ngoko ke, ngaba i-VLDL ikwaluhlobo lwe-cholesterol "embi"?
Ewe, ukuba inqanaba le-VLDL egazini linyuka kakhulu, liwela kudidi "olubi". Nangona imizimba yethu ifuna ubungakanani obuthile be-VLDL ukuze isebenze, xa inqanaba layo linyuka, livula ithuba lesifo sentliziyo kunye nezinye iingxaki zempilo ezininzi.
Ingxaki ephambili yimeko ebizwa ngokuba yi-`(Atherosclerosis).` Ngamafutshane, oku kwenzeka xa amafutha, i-cholesterol, kunye nezinye izinto zakha ngaphakathi kweendonga zemithambo yethu yegazi (imithambo yegazi) kwaye zenze into ebizwa ngokuba yi-``plaque.`` Ezi plaque zinciphisa imithambo yegazi kancinci kancinci, njengothuli oluqokelelana ngaphakathi kombhobho wamanzi. Oku kuthintela ukuhamba kwegazi.
I-VLDL inxulumene njani noku?
Khawuthelekelele ukuba isibindi sethu siqala ukwenza i-VLDL engaphezulu kunokuba siyidinga. Ngoku kukho ii-VLDL ezininzi egazini. Umzimba wethu uyawaqhekeza la ma-VLDL angaphezulu uze uwasebenzisele ukwenza olunye uhlobo lwe-LDL (Low-Density Lipoprotein). I-LDL lolona hlobo luphambili lwe-carrier esilubiza ngokuba yi-"cholesterol embi."
Ngoku igazi lizele ziinxalenye ze-LDL. Le LDL eyongezelelweyo inamathela eludongeni lwemithambo yegazi, apho iqala khona ukwenza iiplaque ezikhankanyiweyo ngaphambili.
Uphando lubonisa ukuba ukuba namanqanaba aphezulu e-VLDL kunye ne-LDL egazini ngaxeshanye kuyingozi ngakumbi kunokuba namanqanaba aphezulu e-elinye lala manqanaba lilodwa.
Akuphelelanga apho, xa i-VLDL iqhekeka emzimbeni kwaye i-LDL yenziwe, kukwakho "neziqwenga" ezishiyekileyo kuloo nkqubo. Ezi zibizwa ngokuba "ziinxalenye eziseleyo". Ezi ziingceba ezincinci ezidla ngokuzaliswa yi-cholesterol. Ngenxa yokuba zincinci ngobukhulu, zinamathela lula eludongeni lwemithambo yegazi, zikhawulezise ukwakheka kwamahlwili.
| Iimeko eziyingozi ezinokubakho ngenxa ye-atherosclerosis (ukuncitshiswa kwemithambo yegazi) | |
|---|---|
| Imeko yezonyango | Ingcaciso elula |
| Isifo seMitha yeCoronary | Ukuncitshiswa kwemithambo yegazi ehambisa igazi entliziyweni, nto leyo eyonyusa umngcipheko wokuhlaselwa sisifo sentliziyo. |
| Isifo seCerebrovascular | Ukuncitshiswa okanye ukuvaleka kwemithambo yegazi ehambisa igazi engqondweni kunokubangela isifo sohlangothi. |
| Isifo semithambo yegazi ejikeleze imithambo yegazi | Amaxesha amaninzi, imithambo yegazi ehambisa igazi emilenzeni iyancitshiswa. Oku kunokubangela iintlungu emilenzeni xa uhamba. |
| I-Aortic Aneurysm | I-aorta, umthambo wegazi oyintloko womzimba, iyabuthathaka kwaye idumbe njengebhaluni. Oku kunokuba yingozi kakhulu ukuba iyadubula. |
Ngaba i-LDL iyingozi ngakumbi? I-VLDL?
Lo ngumbuzo abantu abaninzi abawubuzayo. Enyanisweni, omnye akanakuthiwa "umbi" kunomnye. Zombini zinegalelo elifanayo ekwakhiweni kwe-plaque kwimithambo yegazi. Ke ngoko, zombini ziyingozi ngokulinganayo. Into ebalulekileyo kukulawula amanqanaba azo zombini kwaye uzigcine zikwinqanaba elisempilweni.
Alinganiswa njani amanqanaba e-VLDL? Ngawaphi amaxabiso aqhelekileyo?
Inqanaba le-cholesterol yakho ye-VLDL lilinganiswa ngovavanyo lwegazi olubizwa ngokuba yi-lipid panel . Olu vavanyo ludla ngokwenziwa emva kokuba uzilile iiyure ezili-10-12. Olu vavanyo lubonisa inqanaba le-cholesterol yakho iyonke, i-HDL (elungileyo) cholesterol, i-LDL (embi) cholesterol, kunye namanqanaba e-triglyceride.
Kodwa nantsi into ekhethekileyo. Uninzi lwexesha, iilabhoratri azilinganisi ngqo amanqanaba e-VLDL. Endaweni yoko, zisebenzisa amanqanaba akho e-triglycerides ukubala amanqanaba akho e-VLDL ngefomula yemathematika.
Ngamafutshane, inqanaba lakho le-VLDL lilingana nenqanaba lakho le-triglyceride lahlulwe ngo-5. (Umzekelo, ukuba i-triglycerides yakho yi-150 mg/dL, inqanaba lakho le-VLDL limalunga ne-30 mg/dL).
Nangona kunjalo, ukuba amanqanaba e-triglyceride yomntu aphezulu kakhulu (umz., ngaphezulu kwe-400 mg/dL), le ndlela yokubala isenokungachaneki kakhulu. Kwiimeko ezinjalo, ugqirha wakho unokusebenzisa ezinye iindlela zokulinganisa i-VLDL.
Ngokubanzi, amaxabiso acetyiswayo kumanqanaba e-cholesterol ye-VLDL ngala alandelayo:
- Inqanaba elisempilweni: Ngaphantsi kwe-30 mg/dL (ii-milligrams nge-deciliter nganye).
- Inqanaba eliyingozi/eliphezulu: lilingana okanye lingaphezulu kwe- 30 mg/dL.
Simele senze ntoni ukuba amanqanaba e-VLDL aphakanyisiwe?
Ukuba inqanaba lakho le-VLDL liphezulu, oko kuthetha ukuba usengozini enkulu yokuba nesifo sentliziyo. Kodwa ungakhathazeki, le yimeko elawulekayo.
Xa ugqirha ekunyanga, uza kugxila kakhulu ekunciphiseni amanqanaba akho e-cholesterol ye-LDL kunye ne-triglyceride endaweni yokujolisa ngqo kumanqanaba e-VLDL. Kuba xa loo manqanaba elawulwa, amanqanaba e-VLDL aza kulawulwa ngokuzenzekelayo.
Abantu abaninzi abanamanqanaba aphezulu e-VLDL banokuba nenye okanye ngaphezulu kwezi meko:
- Amanqanaba aphezulu e-triglyceride (i-Hypertriglyceridemia)
- Amanqanaba aphezulu e-cholesterol ye-LDL
- Inqanaba eliphezulu le-cholesterol iyonke (i-Hyperlipidemia)
Nazi ezinye zezinto onokuzenza ukulawula zonke ezi ntlobo zamafutha. Kubalulekile ukuthetha nogqirha wakho ngaphambi kokuba uqale nayiphi na kwezi.
1. Ukulandela ukutya okunempilo kwentliziyo:
- Nciphisa ioyile, ukutya okuqhotsiweyo, nokutya okuqhotsiweyo kakhulu kangangoko kunokwenzeka.
- Nciphisa ukutya neziselo ezineswekile eninzi (iikeyiki, iziselo ezimnandi, itofi).
- Yongeza imifuno emitsha, iziqhamo, imifuno, kunye neenkozo ezipheleleyo (i-buckwheat, irhasi, i-oats) ekutyeni kwakho.
- Khetha intlanzi kunye nenkukhu endaweni yenyama ecutshungulweyo.
2. Ukuzilolonga rhoqo:
- Zilolonge umzimba njengokuhamba ngokukhawuleza, ukukhwela ibhayisekile, okanye uqubhe ubuncinane imizuzu engama-30 ngosuku, ubuncinane iintsuku ezi-5 ngeveki.
- Kubalulekile: Ukuba usandul’ ukuqala ukuzilolonga, cela ingcebiso kugqirha wakho malunga nokuba zeziphi iindlela zokuzilolonga ezifanelekileyo kuwe.
3. Ukugcina ubunzima obusempilweni:
- Kubaluleke kakhulu ukugcina ubunzima obufanelekileyo obuhambelana nobude bakho. Ukuba utyebile kakhulu, ukunciphisa umzimba kunokunciphisa kakhulu amanqanaba akho e-cholesterol kunye ne-triglyceride.
4. Ukuthatha amayeza ngengcebiso kagqirha:
- Kwezinye iimeko, utshintsho lwendlela yokuphila lunokwanela ukulawula amanqanaba akho e-cholesterol. Kwiimeko ezinjalo, ugqirha wakho unokukunika amayeza anjenge-"statins. " Kubaluleke kakhulu ukuthatha amayeza achazwe ngugqirha wakho kwidosi echanekileyo kwaye ixesha elifanelekileyo.
Ngamanye amaxesha, amanqanaba e-triglyceride kunye ne-VLDL anokunyuka ngenxa yezinye iimeko zonyango ezifana nesifo seswekile, iingxaki ze-thyroid, okanye amanye amayeza owasebenzisayo. Ke ngoko, ukuba unemibuzo malunga namaxabiso akwingxelo yakho, thetha nogqirha wakho. Ungakhathazeki, ngolwalathiso olufanelekileyo kunye nonyango, le meko inokulawulwa kakuhle.
Umyalezo Wokuya Ekhaya
- I-VLDL sisixhobo esikhethekileyo esenziwe sisibindi sethu esithwala ikakhulu ii-triglycerides (uhlobo lwamafutha) emzimbeni wonke.
- Inqanaba le-VLDL egazini elingaphezulu kwe-30 mg/dL liyingozi kwimpilo yentliziyo. Linokukhokelela ekuncipheni kwemithambo yegazi (i-atherosclerosis).
- Amanqanaba e-VLDL awasoloko elinganiswa ngokuthe ngqo. Abalwa ngokwezinga lakho le-triglyceride.
- Eyona ndlela ilungileyo yokulawula i-VLDL kukulawula amanqanaba e-triglyceride kunye ne-LDL (embi) ye-cholesterol.
- Amanqanaba e-VLDL anokulawulwa ngokulandela ukutya okunempilo kwentliziyo, ukuzilolonga rhoqo, ukugcina ubunzima obusempilweni, kunye nokuthatha amayeza njengoko kumiselwe ngugqirha wakho.
- Ukuba unenkxalabo malunga nengxelo yakho ye-cholesterol, qiniseka ukuba uyixoxa nogqirha wakho.
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