Ngaba wakha weva ngegama elithi G6PD? Mhlawumbi ugqirha ukuxelele ngalo, okanye mhlawumbi umntu othile kusapho lwakho ukuxelele ngalo. Okanye mhlawumbi yinto entsha kuwe. Nangona kunjalo, ungoyiki xa usiva eli gama. Ukungabikho kwe-G6PD sisifo esiqhelekileyo semfuza esichaphazela abantu abamalunga nezigidi ezingama-400 kwihlabathi liphela. Kufana notshintsho oluncinci emizimbeni yethu kunokuba sisifo. Ngoko masithethe ngayo yonke into ngokulula nangendlela enobuhlobo namhlanje.
Yintoni kanye kanye into yokunqongophala kwe-G6PD?
Kulungile, masiyibeke ngokulula le nto. Igazi lethu liqulathe uhlobo lweseli olubizwa ngokuba ziiseli ezibomvu zegazi . Ezi seli zithwala ioksijini emizimbeni yethu yonke. Kufana nesithuthi esithwala impahla ukuya endlwini.
Ngoku, kukho i-enzyme ekhethekileyo enceda ezi seli zibomvu zegazi ukuba zihlale ziphilile kwaye zomelele. Siyibiza ngokuba yi-'Glucose-6-Phosphate Dehydrogenase', okanye i-G6PD ngamafutshane. Cinga ngale enzyme njengomkhuseli weeseli ezibomvu zegazi, okanye 'umbane' ozinika amandla. Le enzyme ye-G6PD ikhusela iiseli ezibomvu zegazi kwezinye zezinto eziyingozi egazini.
Okwenzekayo emzimbeni womntu onesifo se-G6PD kukuba i-enzyme ye-G6PD ayiveliswanga ngokwaneleyo. Okanye i-enzyme eveliswayo ayisebenzi kakuhle. Oku kukufuzwa njengelifa . Oko kuthetha ukuba uyizuza njengelifa kumama okanye kutata wakho, kwaye ayisosifo esosulelayo.
Ngokwesiqhelo, ukuba nokungabikho kwe-G6PD akuyongxaki inkulu. Nangona kunjalo, ukuba uthatha amayeza athile, iikhemikhali, okanye ukutya okuthile (ingakumbi iintlobo ezithile zeembotyi), iiseli ezibomvu zegazi ziqala ukonakala kuba loo mkhuseli akakho. Oku sikubiza ngokuba yi-'hemolytic anemia.' Makhe sijonge ngakumbi.
Zithini iimpawu? Siyibona njani le nto?
Into emangalisayo apha kukuba abantu abaninzi abanesifo se-G6PD ababonisi zimpawu . Baphila ubomi obuqhelekileyo. Ingxaki ivela kuphela xa befumana enye 'yezinto ezibangela isifo' esizikhankanyileyo ngaphambili, oko kukuthi, iyeza elibi okanye ukutya.
Nangona kunjalo, ngamanye amaxesha umntwana unokuba ne-jaundice (ukujika kwesikhumba kube tyheli) emva kokuzalwa, nto leyo edla ngokunyangwa lula.
Ukuba umntu onesifo se-G6PD uchaphazeleka yinto enobungozi, unokuba nesifo esibizwa ngokuba yi-'hemolytic anemia.' Ngamafutshane, oku kwenzeka xa iiseli ezibomvu zegazi ziqhekeka kwaye zitshatyalaliswa ngokukhawuleza kunokuba zinokwenziwa. Iiseli ezibomvu zegazi zezona zithwala ioksijini emzimbeni. Ngoko ke xa zitshatyalaliswa, amalungu omzimba awafumani ioksijini ayidingayo.
Ukuba le meko ye-'hemolytic anemia' iyenzeka, inokuba yingozi kakhulu. Kungoko ke, kubaluleke kakhulu ukuzazi ezi mpawu.
Le theyibhile ingezantsi idwelisa iimpawu eziqhelekileyo ze-hemolytic anemia.
| Uphawu | Inkcazo |
|---|---|
| Ulusu olukhanyayo | Ulusu lujika umbala lube mthubi, ngokungathi umzimba awunalo igazi. |
| Ukutyheli kolusu namehlo (i-Jaundice) | I-Bilirubin, into eveliswa xa iiseli ezibomvu zegazi ziqhekeka, ibangela ukuba ulusu kunye nabamhlophe bamehlo bajike babe tyheli. |
| Umchamo omnyama | Umchamo ujika ube mdaka okanye ube nombala we-cola. |
| Ifiva | Usenokuziva unomkhuhlane ngaphandle kwesizathu. |
| Ukudinwa kunye nobuthathaka | Ukuziva ungenabomi, uphelelwa ngumphefumlo, kwaye udiniwe kakhulu. |
| Ukudideka | Xa ingqondo ingafumani ioksijini eyaneleyo, ungaziva udidekile kwaye udidekile. |
| Ukubetha kwentliziyo | Isantya sentliziyo siyanda. |
Ukuba ezi mpawu zinzima kwaye zihlala zikho, kufuneka ubone ugqirha ngoko nangoko . Ngamanye amaxesha kunokufuneka uye kwiSebe lezeMpilo eziNgxamisekileyo (ETU) lesibhedlele.Kusenokufuneka isuswe. Kodwa kwiimeko ezininzi, xa unobangela wale meko ususiwe, uya kuphola ngokwawo kwisithuba seeveki ezimbini.
Yintoni isizathu sale nto? Ngubani onokuba nayo ngakumbi?
Njengoko besitshilo ngaphambili, ukungabikho kwe-G6PD yimeko yemfuza ngokupheleleyo . Oku kuthetha ukuba uyizuza njengelifa kubazali bakho. Akukho ndlela yokuyithintela.
Nangona kunjalo, amanye amaqela abantu anokuba nale meko.
- Kwamadoda (ngaphezu kwabasetyhini).
- Kwabo bakwiilizwe zaseAfrika, eAsia, eMbindi Mpuma, nakwimimandla yeMeditera.
Ukuba uyazi ukuba kukho umntu kusapho lwakho onesifo se-G6PD, kukho ithuba lokuba nawe usenokuba naso. Ngoko ke licebo elihle ukuthetha nogqirha wakho ngaso.
Ufumanisa njani ukuba unesifo se-G6PD?
Kukho indlela elula kakhulu yokufumanisa. Oko kukwenza uvavanyo lwegazi . Ugqirha wakho uza kukucebisa olu vavanyo ngokusekelwe kwimbali yosapho lwakho kunye nokuba uneempawu.
Ngokwesiqhelo, uvavanyo lokuhlola lwenziwa kuqala ukuze kubonwe ukuba kukho ukungabikho kwe-G6PD na. Ukuba kubonisa ukuba kukho ukungabikho, kwenziwa olunye uvavanyo ukuze kubonwe ukuba yingozi kangakanani na. Uvavanyo lwe-`Beutler` lolunye lolo vavanyo.
Ngale mvavanyo, ungafumanisa ukuba unesiphene se-G6PD na, kwaye ukuba kunjalo, inqanaba lakho lingakanani.
Ungaphila njani nokungabikho kwe-G6PD? Zithini izinto ekufuneka uziphephe?
Le yeyona nxalenye ibalulekileyo. Ukuba ufunyaniswe une-G6PD deficiency, akukho nyango luthile lufunekayo . Okufuneka ukwenze kukuphepha 'izinto ezibangela' ukonakalisa iiseli zakho ezibomvu zegazi kwaye zibangele imeko ebizwa ngokuba yi-hemolytic anemia.
Oko kuthetha ukuba kufuneka uwaphephe ngokupheleleyo amayeza athile, iikhemikhali, kunye nokutya. Ezi zibizwa ngokuba zizinto ezibangela 'uxinzelelo lwe-oxidative'.
Khumbula itheyibhile engezantsi. Kubaluleke kakhulu ukuzigcina ezi zinto zingangeni ebomini bakho.
| Izinto ekufuneka abantu abanesifo se-G6PD baziphephe ngokuqinisekileyo | |
|---|---|
| Uhlobo | Imizekelo |
| Ukutya | Iimbotyi zeFava - Oku kukutya okubaluleke kakhulu nokuyingozi. Kwamanye amazwe, ezi zikwabizwa ngokuba ziimbotyi ezibanzi. |
| Amayeza | Ezinye iipilisi zokuthomalalisa iintlungu (umz., i- aspirin enedosi ephezulu) |
| Ii-antibiotics ezine-"Sulfonamides" (umz. iiSulfonamides) | |
| Amayeza okulwa nemalariya aqulethe "i-quine" | |
| Iikhemikhali | I-Naphthalene - Ezi zifumaneka kwiibhola zeenkuni ezibekwe kwiikhabhathi. Kwanokuphefumla ivumba lazo kuyingozi. |
Kubalulekile: Ukuba une-G6PD deficiency, kufuneka uxelele ugqirha wakho ngalo lonke ixesha xa umbona. Emva koko, xa ekubhalela amayeza, uya kukhetha amayeza akhuselekileyo kuwe. Ungaze uthathe naliphi na iyeza ngaphandle kokubonisana nogqirha kuqala.
Umyalezo Wokuya Ekhaya
- Ukunqongophala kwe-G6PD akusosifo esoyikwayo. Yimeko yemfuza abantu abaninzi emhlabeni abanayo, kwaye idluliselwa kwizizukulwana ngezizukulwana.
- Abantu abaninzi abanazo iimpawu kwaye bagula kuphela xa befumana amayeza angalunganga, ukutya (ingakumbi iimbotyi ze-fava), okanye iikhemikhali.
- Ukuze uphumelele ekulawuleni ubomi bakho, kufuneka wazi kakuhle ukuba zeziphi izinto ezikukhathazayo kwaye uziphephe.
- Ukuba ufumana iimpawu ezinje ngomkhuhlane, ukudinwa kakhulu, ukutyheli kolusu, kunye nomchamo omnyama, bonana nogqirha ngokukhawuleza.
- Khumbuza ugqirha wakho ngalo lonke ixesha xa umbona ukuba une-G6PD deficiency. Kubaluleke kakhulu kukhuseleko lwakho.
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