Ake sifunde kabanzi nge-hormone i-estriol, ebalulekile ekukhuleni komntwana wakho.

Uma ukhulelwe, cishe usuqaphele izinguquko eziningi ezenzeka emzimbeni wakho. Eziningi zalezi zinguquko zibangelwa ama-hormone. Ngakho-ke, namuhla sizokhuluma nge-hormone ebaluleke kakhulu ngesikhathi sokukhulelwa, kodwa kungenzeka ukuthi awukaze uzwe ngayo. Ibizwa ngokuthi i-estriol.

Iyini le estriol?

Kalula nje, i-estriol ingenye yezinhlobo ezintathu zama-hormone e-estrogen emizimbeni yethu. Ikakhulukazi uma ukhulelwe, amazinga akho e-estriol ayanda phakathi nokukhulelwa kwakho. Lokhu kusiza ukugcina ingane yakho kanye nesibeletho sakho siphilile. Ifinyelela esicongweni sayo ngaphambi nje kokubeletha.

I-Estriol ikhiqizwa emzimbeni wabesifazane nabesilisa abangakhulelwe. Kodwa-ke, inani lincane kakhulu, ngezinye izikhathi alibonakali. Amanye amagama ayo yi-'oestriol' kanye ne-E3.

Kwenzekani ku-estriol ngesikhathi sokukhulelwa?

Uma kuqhathaniswa namanye ama-hormone e-estrogen, i-estriol inendima ekhethekile ngesikhathi sokukhulelwa. Nakhu ekwenzayo:

• Kusiza isibeletho sakho sikhule: Njengoba ingane yakho ikhula, isibeletho sakho sidinga ukukhula ukuze sivumelane nayo. Yilokho i-estriol esiza ngakho. Cabanga ngakho njengokwenzela ingane indawo.
• Izwela umzimba kwamanye ama-hormone okukhulelwa: I-Estriol isiza umzimba wakho ukuthi usabele kahle kwamanye ama-hormone abalulekile asebenzayo ngesikhathi sokukhulelwa. Okusho ukuthi, ivula indlela yokuba amanye ama-hormone enze imisebenzi yawo ngendlela efanele.
• Kulungiselela umzimba ukubeletha nokuncelisa: Kuthiwa lokhu kusiza ukulungiselela umzimba wakho ukubeletha kanye nokuncelisa kamuva. Akumangalisi lokhu?

Amazinga e-Estriol avame ukuqala ukukhuphuka cishe emavikini ayisishiyagalombili ukhulelwe. Ayaqhubeka nokukhuphuka. Afinyelela esicongweni cishe emavikini amathathu ngaphambi kokubeletha. Abanye abacwaningi bacabanga ukuthi la mazinga e-estriol akhuphukayo ayingxenye yokulungiselela komzimba ukubeletha. Kodwa abakaqiniseki okwamanje, futhi basacwaninga ngakho.

I-Estriol njengomuthi

Manje sesikhulume nge-estriol, ekhiqizwa ngokwemvelo emzimbeni. Kukhona nohlobo lwe-estriol olwenziwa elebhu. Lokhu kubizwa ngokuthi i-bioidentical hormone. Lokho kusho ukuthi lwenzelwe ukubukeka njenge-hormone esinayo emizimbeni yethu. Ngezinye izikhathi odokotela bangase batuse lokhu njengokwelashwa kwama-hormone ezimpawu zokunqamuka kokuya esikhathini. Uyazi, yize ukunqamuka kokuya esikhathini kuyingxenye yemvelo yokuphila kowesifazane, kungaba yinto ecasulayo kancane, njengokushisa okukhulu nokungalali.

Kodwa kukhona into encane lapha.Lo muthi awuvunyelwe yi-Food and Drug Administration (FDA) ukwelapha izimpawu zokunqamuka kokuya esikhathini. Esikhathini esiningi, lokhu kutholakala kuphela kumakhemisi akhethekile, noma kumakhemisi ahlanganisiwe. Ngakho-ke, ngaphambi kokuthi uqale ukusebenzisa into efana nale , kufanele ukhulume nodokotela wakho. Nguye ozokutshela ukuthi ikulungele yini.

Abacwaningi basaphenya ngezinye izindlela zokusebenzisa i-estriol. Bacabanga ukuthi i-estriol eyenziwe elebhu ingasiza futhi kulokhu:

• Thuthukisa ukusebenza kwengqondo. Lokho kusho izinto ezifana nenkumbulo nokunaka.
• Nciphisa ubuhlungu bekhanda ngesikhathi sokuya esikhathini.
• Nciphisa imibimbi yesikhumba.
• Yelapha izifo ezihambisana nokuvuvukala ohlelweni lwezinzwa, isibonelo, i-multiple sclerosis (MS).
• Yelapha ukucindezeleka kwangemva kokubeletha.

Kodwa khumbula, lezi zinzuzo zisesesigabeni socwaningo (ukusetshenziswa ngaphandle kwelebula) futhi azikafakazelwa ngokugcwele. Ngakho-ke kufanele ukhulume nodokotela wakho ngaphambi kokusebenzisa i-estriol ngale njongo.

I-estriol ikhiqizwa kanjani emzimbeni?

Esikhathini esiningi, i-placenta inesibopho sokukhiqiza i-estriol. I-placenta iyisitho esibaluleke kakhulu esihlinzeka ngomsoco nomoya-mpilo enganeni ngesikhathi sokukhulelwa. Kodwa kunezinyathelo eziningana ezihilelekile ekukhiqizweni kwe-estriol. Cabanga ngalokhu:

1. Okokuqala, izindlala ze-adrenal zengane yakho zikhiqiza i-hormone ebizwa ngokuthi i-dehydroepiandrosterone sulfate (DHEAS). Lesi yisithako sokuqala.

2. Ngemuva kwalokho, isibindi somntwana siguqula le DHEAS ibe enye ikhemikhali ebizwa ngokuthi i-16a-hydroxy-DHEAS. Lokhu kwenzeka nangaphakathi emzimbeni womntwana.

3. Leli khemikhali liya ku-placenta bese liguqulwa libe yi-estriol. I-placenta ifana nefektri ethatha leli khemikhali bese yenza i-estriol.

4. Ekugcineni , le estriol ekhiqizwayo ingena egazini lakho. Yilapho-ke kuphela lapho isiza khona umzimba wakho kanye nomntwana.

Uyabona, lokhu kuyinqubo eyinkimbinkimbi kancane. Kodwa uma sikubeka kalula, izingxenye zomzimba womntwana kanye ne-placenta ziyahlangana ukuze zenze le hormone ebalulekile. Lokhu kukhombisa ukuthi isibopho phakathi kukamama nomntwana simangalisa kangakanani!

Odokotela bahlola nini amazinga e-estriol?

Odokotela bavame ukuhlola amazinga e-estriol phakathi kwamasonto ayi-15 nama-20 okukhulelwa (ngesikhathi se-trimester yesibili).Lokhu kwenziwa njengengxenye yokuhlolwa okubizwa ngokuthi i-triple marker noma i-quad marker screening. Lokhu kuhlolwa kusiza ukuthola ukuthi ingane inazo yini izimo zokuzalwa/iziphambeko zokuzalwa. Lokhu kuhlolwa okubaluleke kakhulu ngoba uma kukhona okutholakala kusenesikhathi, kungathathwa izinyathelo ezidingekayo.

Ukuhlolwa kwe-quad marker kulinganisa amazinga ama-hormone estriol kanye ne-human chorionic gonadotropin (HCG), kanye ne-alpha-fetoprotein (AFP) kanye ne-inhibin-A. Odokotela basebenzisa konke lokhu ndawonye ukuze bathole isifo.

Uma unezici eziyingozi zalezi zimo zokuzalwa, udokotela wakho angase akuncome ukuhlolwa kwegazi le-estriol noma ukuhlolwa kwe-quad. Yiziphi lezo zici eziyingozi?

• Ukuba neminyaka engaphezu kwengu-35 ubudala (ubudala obuphezulu bomama).
• Uma unesifo sikashukela .
• Uma othile emndenini eke waba nezimo ezinjalo kusukela ekuzalweni (umlando womndeni wemvelo).
• Uma uthola izifo ezibangelwa amagciwane njenge-Hepatitis A noma i-Zika virus ngesikhathi sokukhulelwa.

Uma kwenzeka into efana nale, ungakhathazeki. Udokotela uzokunikeza iseluleko esidingekayo.

Amazinga e-estriol alinganiswa kanjani?

Ngesikhathi sokukhulelwa, ungathola ukuhlolwa kwegazi noma ukuhlolwa komchamo ukuze kulinganiswe amazinga akho e-estrogen, ikakhulukazi i-estriol. Ukuhlolwa kwegazi kulula kakhulu. Kuhilela ukuthatha igazi elincane kudokotela wakho noma elebhu. Kungase kube buhlungu kancane, kodwa kuzophela ngokushesha.

Kodwa indlela enembile kakhulu yokukala amazinga e-estriol iwukuhlolwa komchamo kwamahora angama-24. Kulokhu, uqoqa umchamo wakho esitsheni amahora angama-24 bese uwuyisa kudokotela wakho noma elebhu. Nakuba lokhu kungase kubonakale kuyinkinga, kuyasiza ukuthola umphumela onembile.

Namuhla, kunezivivinyo zasekhaya ezingalinganisa amazinga e-estrogen ematheni. Kodwa uma ukhulelwe, udokotela wakho cishe uzoncoma indlela ethembekile, njengoba ukuhlola ngesikhathi sokukhulelwa kubaluleke kakhulu.

Kusho ukuthini amazinga e-estriol angajwayelekile?

Amazinga aphansi e-estriol ngesikhathi sokukhulelwa angabonisa inkinga nge-placenta . Ngezinye izikhathi kungabonisa noshintsho enganeni, njenge- Down syndrome . Kodwa khumbula, lokhu akuyona into engatholakala ngokuhlolwa okukodwa nje. Kudingeka ukuhlolwa okwengeziwe ukuqinisekisa ukuxilongwa.

Ngakolunye uhlangothi, ngesikhathi sokukhulelwaUma amazinga akho e-estriol ekhuphuka ngokuzumayo ngaphambi kwamasonto angu-37, kungase kusho ukuthi usengozini yokubeletha ngaphambi kwesikhathi. Uma kunjalo, udokotela wakho uzokunikeza iseluleko kanye nokwelashwa okudingekayo.

Futhi, labo abanamazinga aphansi e-estriol eduze kokubeletha bangase bangasitholi isikhathi sokubeletha ngokwemvelo. Kuleso simo, odokotela kungadingeka basebenzise ezinye izindlela ukuze babangele ukubeletha (izindlela zokuqalisa ukubeletha).

Udokotela wakho uzokuchazela le miphumela yokuhlolwa nokuthi isho ukuthini. Ungesabi ukubuza imibuzo. Kuye ngemiphumela, bangase batuse ukuhlolwa okwengeziwe (njenge-ultrasound) noma bakuthumele kumeluleki wezakhi zofuzo.

I-Estriol iyi-hormone edlala indima ebaluleke kakhulu ngesikhathi sokukhulelwa. Udokotela wakho angase afune ukuhlola amazinga akho e-estriol kanye nezinye izivivinyo ngesikhathi sokukhulelwa kwakho. Kuvamile ukuzizwa ukhathazekile lapho umphumela wokuhlolwa ubuya ungajwayelekile. Kodwa khumbula, udokotela wakho uzokuchazela imiphumela futhi akunike ukwesekwa okudingayo.

Ngakho-ke, yini okufanele siyikhumbule kulokhu?

Kulungile, ngakho-ke ukukubeka kalula, i-estriol iyi-hormone ebalulekile kuwe nakumntwana wakho ngesikhathi sokukhulelwa. Isiza isibeletho sikhule, umntwana akhule kahle, futhi umzimba ulungiselele ukubeletha. Odokotela babheka amazinga ayo ukuze basize ekutholeni izimo ezithile kusenesikhathi.

Into ebaluleke kakhulu ukuthi uma unemibuzo noma ukukhathazeka ngamazinga akho e-estriol noma ukuhlolwa okuhlobene, khuluma nodokotela wakho. Bangabantu abangcono kakhulu ukukuchazela bona futhi bakunike isiqondiso osidingayo. Ngakho ungesabi ukubuza imibuzo futhi ucacise ngakho konke. Impilo yakho neyengane yakho yizona zinto ezibaluleke kakhulu.

I- Estriol, ukukhulelwa, ama-hormone, i-placenta, ukubeletha, uphawu lwe-quad, i-estrogen