Ukuhlolwa kwe-CRP (Ukuhlolwa kwe-C-Reactive Protein) - Ake sixoxe ngalokhu!

Cishe uke wezwa ngokuhlolwa kwe-CRP. Mhlawumbe udokotela wakho ukutshelile ukuthi ukwenze. Noma mhlawumbe uke wezwa ukuthi umngane noma isihlobo sakhe senze lokhu kuhlolwa. Ngakho-ke, kuyini lokhu kuhlolwa kwe-CRP? Kungani kubaluleke kangaka? Ake sixoxe ngakho konke lokhu ngendlela elula namuhla, ngendlela ongayiqonda, kulungile?

Kuyini i-CRP? Kungani ibalulekile emzimbeni wethu?

Kulungile, ake siqale sibone ukuthi iyini i-CRP. I-CRP isifinyezo se- C-Reactive Protein . Lolu uhlobo olukhethekile lweprotheyini elakhiwa yisibindi sethu. Manje ungase uzibuze, kwenzekani kulokhu? Uma kukhona ukuvuvukala endaweni ethile emzimbeni wethu, isibindi sisabela ngokwenza le phrotheyini ebizwa ngokuthi i-CRP bese siyifaka egazini.

Manje ungase uzibuze, 'Kuyini ukuvuvukala?' Kalula nje, ukuvuvukala kuyindlela yokusabela kwesistimu yokuzivikela yomzimba wethu. Cabanga ngegciwane noma amagciwane angena emzimbeni wakho, noma uthola ukulimala, njengokusikeka noma ukusikeka. Ngemuva kwalokho isistimu yethu yokuzivikela yomzimba iyavuselelwa. Kufana nebutho elivikela izwe lethu. Lesi simiso sokuzivikela komzimba sikhipha amangqamuzana akhethekile, abizwa ngokuthi amangqamuzana okuvuvukala nama-cytokine , ukulwa namagciwane noma ukuphulukisa indawo elimele. Yilapho ukuvuvukala, ukubomvu, ubuhlungu, futhi ngezinye izikhathi kwenzeka khona ukufudumala. Yilokhu esikubiza ngokuthi ukuvuvukala. Ngezinye izikhathi lokhu kuvuvukala kungenzeka hhayi ezindaweni esingazibona kuphela, kodwa nasezindaweni ezingaphakathi komzimba esingenakuzibona, njengamalunga.

Ngakho-ke, uma kukhona ukuvuvukala, inani le-CRP egazini liyakhuphuka. Ngokuvamile, igazi lethu linezinga eliphansi kakhulu le-CRP. Kodwa-ke, lapho ukuvuvukala kukhuphuka, leli zinga le-CRP nalo liyakhuphuka. Okusho ukuthi, ngokubheka izinga le-CRP egazini, odokotela bangathola umbono wokuthi kukhona ukuvuvukala emzimbeni wethu nokuthi kukhulu kangakanani.

Ukuhlolwa kwe-CRP kwenziwa nini?

Ngakho-ke, odokotela batusa nini ukwenza lokhu kuhlolwa kwe-CRP? Yini engalindelwa kulokhu?

Ukuhlolwa kwe-CRP kusetshenziselwa kakhulu ukusiza ekuxilongeni noma ekuqinisekiseni ukuba khona kwezimo ezithile zezokwelapha. Nazi izibonelo ezimbalwa:

• Ezinye izifo ezibangelwa amagciwane ezinzima, njenge -sepsis, zingaba yingozi empilweni.
• Ukutheleleka ngefungus.
• Ukutheleleka okubangelwa amagciwane angena emathanjeni kubizwa ngokuthi i-osteomyelitis . Lokhu futhi ukutheleleka okungathi sína.
• Izimo zokuvuvukala ezenzeka emathunjini, okungukuthi, i-Inflammatory Bowel Disease (IBD) .
• Ezinye izinhlobo ze-arthritis, njenge-rheumatoid arthritis.
• Ezinye izifo ziyizifo ezizimele lapho amasosha ethu omzimba esiphendukela khona, isibonelo , i-rheumatoid arthritis noma i-lupus (Systemic Lupus Erythematosus - SLE) .
• Isifo Sokuvuvukala Kwesinqe (PID) yisimo sokuvuvukala kwesinqe kwabesifazane.

Cabanga ukuthi ingane yakho inomkhuhlane ophakeme izinsuku ezimbalwa, ayidli, futhi iphatheke kabi kakhulu. Udokotela angase ayale ukuhlolwa kwe-CRP ukuze anqume ngokushesha ukuthi kukhona yini ukutheleleka okukhulu, mhlawumbe ukutheleleka ngamagciwane, emzimbeni. Imiphumela yalokhu izonquma inkambo elandelayo yokwelashwa.

Akukhona lokho kuphela, lokhu kuhlolwa kwe-CRP kusiza futhi ukuhlola ukutheleleka kwebhaktheriya ngesikhathi senqubo yokuphulukiswa, kungakhathaliseki ukuthi kungemuva kokuhlinzwa okukhulu noma inqubo yokuhlasela.

Kodwa into eyodwa okufanele uyikhumbule ukuthi ukuhlolwa kwe-CRP kukodwa akukwazi ukukutshela ngokuqinisekile, 'Lesi yisifo lapha' noma 'Lokhu ukuvuvukala kule ngxenye yomzimba.' Ngakho-ke, uma inani le-CRP liphezulu, udokotela uvame ukwenza ezinye izivivinyo ezimbalwa ukuthola imbangela eqondile.

Ngidinga nini ukuhlolwa kwe-CRP?

Manje ungase uzibuze, 'Ngakho-ke ngidinga nini ukuthola lokhu kuhlolwa kwe-CRP?' Udokotela ngokuvamile uzoyala lokhu kuhlolwa uma ubonisa izimpawu zokutheleleka okukhulu kwebhaktheriya. Lezi zimpawu zifaka:

• Ngithola umkhuhlane omkhulu.
• Umzimba uzizwa ubanda futhi uqhaqhazela (Ukugodola).
• Ukwanda kwesilinganiso sokuphefumula (i-tachypnea).
• Ukwanda kwesilinganiso senhliziyo (i-tachycardia).
• Isicanucanu nokuhlanza kuyaphela.

Ngaphezu kwalokho, uma usuvele welashwa ngenxa yokutheleleka noma uma welashwa ngesimo sokuvuvukala esingamahlalakhona, odokotela basebenzisa lolu vivinyo lwe-CRP ukuze babone ukuthi ukwelashwa kuyasebenza yini nokuthi ukuvuvukala kwehlile yini. Lokhu kungenxa yokuthi lapho ukuvuvukala emzimbeni kwehla, izinga le-CRP nalo liyehla. Lokhu kusho ukuthi ukwelashwa kuyasebenza.

Ubani owenza ukuhlolwa kwe-CRP? Kwenziwa kanjani?

Lokhu kuhlolwa kwe-CRP kuvame ukwenziwa ngumuntu oqeqeshwe ngokukhethekile, obizwa ngokuthi i-phlebotomist, odonsa igazi. Kodwa-ke, noma yisiphi isisebenzi sezempilo esiqeqeshwe ukudonsa igazi singakwenza. Isampula yegazi ithunyelwa elabhorethri. Usosayensi welabhorethri yezokwelapha lapho ulungisa isampula ukuze ihlolwe futhi usebenzisa imishini ekhethekile, ebizwa ngokuthi ama-analyzer, ukuhlola izinga le-CRP.

Ingabe kukhona okukhethekile okufanele ukulungiselele ngaphambi kwalolu vivinyo?

Esikhathini esiningi, cha. Nakuba ukuhlolwa kwegazi okunye kudinga ukuzila ukudla, ukuhlolwa kwe-CRP ngokuvamile akudingi zinyathelo ezikhethekile zokuqapha. Kodwa-ke, uma udokotela wakho ekunika noma yimiphi imiyalelo ekhethekile, kufanele nakanjani uyilandele, akunjalo?

Kwenzekani uma unikela ngegazi?

Kulungile, manje ake sibone ukuthi kwenzekani uma unikela ngegazi. Nakhu ozobhekana nakho:

• Uzohlaliswa esihlalweni. Isisebenzi sezempilo sizobe sesibheka izingalo zakho bese sikhetha umthambo olula wokukhipha igazi kuwo. Lokhu kuvame ukuba ngaphakathi kwengalo yakho, ngemuva nje kwendololwane yakho.
• Uma sekutholakale umthambo, indawo iyahlanzwa kahle bese kufakwa umuthi wokubulala amagciwane.
• Ngemuva kwalokho, kufakwa inaliti encane emthanjeni bese kuthathwa isampula yegazi. Ngalesi sikhathi, ungase uzizwe umuzwa omncane wokuhlaba, njengokulunywa yintuthwane .
• Ngemva kokufaka inaliti, igazi elincane liqoqwa epayipini lokuhlola.
• Ngemva kokuba isampula yegazi isiqoqiwe, inaliti iyasuswa bese kubekwa ucezu lwekotini noma i-gauze phezu kwendawo ukuze kumiswe ukopha bese lugcinwa endaweni yalo isikhathi esifushane.
• Ekugcineni, kufakwa ibhandishi endaweni. Yilokho kuphela, umsebenzi usuqedile.

Yonke inqubo ithatha imizuzu engaphansi kwemihlanu, ngakho-ke akukho okufanele ukhathazeke ngakho.

Kwenzekani ngemva kokuhlolwa kwe-CRP? Ingabe zikhona izingozi?

Ngemva kokuthathwa kwesampula yegazi lakho, lithunyelwa elabhorethri ukuze lihlolwe. Uma umbiko ubuya, ngokuvamile phakathi nosuku olulodwa noma ezimbili, kungathatha isikhathi eside, futhi udokotela wakho uzokutshela imiphumela.

Manje ake sibone ukuthi zikhona yini izingozi zokuthola lokhu kuhlolwa kwegazi. Empeleni, ukuhlolwa kwegazi kuyinto evamile kakhulu futhi edingekayo kwezokwelapha. Akukho bungozi obukhulu nhlobo. Indawo lapho igazi likhishwa khona ingase ibe buhlungu kancane, noma kube nokuklwebheka okuncane. Kodwa lokho kuzophola ngokushesha ezinsukwini ezimbalwa.

Yini ekhona embikweni we-CRP? Yiziphi izindinganiso ezijwayelekile?

Umbiko we-CRP owutholayo uvame ukuqukethe imininingwane efana nale:

• Igama lokuhlolwa kwegazi lisho lokho okulinganiswa egazini (isib. i-C-Reactive Protein).
• Umphumela wokuhlolwa kwegazi lakho, okungukuthi, inani elifanele.
• Ububanzi bokulinganisa obujwayelekile balolo vivinyo.
• Ishadi elibonisa ukuthi umphumela wakho ujwayelekile, awujwayelekile, uphezulu, noma uphansi.

Manje ake sibone ukuthi liyini inani elijwayelekile le-CRP. Lawa mabanga okubhekisela angahluka kancane kusuka kwelebhu kuya kwelebhu. Uma uthola umbiko, uzosho ukuthi liyini inani elijwayelekile le-CRP laleyo lebhu.

Kodwa ngokuvamile, izinga elijwayelekile le-CRP lingaphansi kuka-0.9 mg/dL (ama-milligram nge-deciliter ngayinye). Amanye ama-lab aze athi lingaphansi kuka-1.0 mg/dL.

Kunezizathu eziningi zokuthi kungani amazinga e-CRP engashintsha. Ngezinye izikhathi, amazinga e-CRP angakhuphuka kancane , okuhlanganisa:

• Ukubhema ugwayi.
• Umkhuhlane ovamile.
• Izimo zengqondo ezifana nokucindezeleka.
• Isifo sikashukela.
• Izinkinga zokulala (Ukungalali).
• I-Gingivitis.
• Ukukhuluphala ngokweqile kusho ukukhuluphala ngokweqile.
• Izimo zokuvuvukala ezihlobene nezimpande zamazinyo (i-Periodontitis).
• Ukukhulelwa.
• Ukulimala kwamuva nje, njengokukhubeka ngenxa yokuwa.

Isibonelo, uma ubhema ugwayi nsuku zonke, izinga lakho le-CRP lingase libe phezulu kancane kunezinye, ngisho noma ungenaso isifo esikhulu. Futhi, uma ukhuluphele kakhulu (ukhuluphele kakhulu), lokho kungabangela nokuthi izinga lakho le-CRP libe phezulu kancane. Lokhu yilokho esikubiza ngokuthi 'imiphumela yendlela yokuphila'.

Futhi, abesifazane nabantu asebekhulile bangase babe namazinga e-CRP aphezulu kancane ngokwemvelo. Uma unemibuzo mayelana nombiko wakho, qiniseka ukuthi ubuza udokotela wakho ukuze akucacisele.

Kusho ukuthini ukuthi izinga le-CRP liphezulu? Kusho ukuthini?

Kulungile, manje ake sibheke ukuthi kusho ukuthini uma i-CRP yakho iphezulu embikweni wakho. Uma i-CRP yakho iphakeme kakhulu kusukela ezingeni elijwayelekile , cishe kusho ukuthi kukhona ukuvuvukala endaweni ethile emzimbeni wakho. Kodwa njengoba ngishilo ngaphambili, ukuhlolwa kwe-CRP kukodwa akukwazi ukukutshela kahle ukuthi yini ebangela ukuvuvukala noma ukuthi kukuphi emzimbeni wakho. Ngakho-ke, uma i-CRP yakho iphezulu, udokotela wakho cishe uzokwenza ezinye izivivinyo ezimbalwa.

Kuye ngokuthi inani le-CRP liphakeme kangakanani, lokho elikushoyo kungahluka.

Uma inani le-CRP liphakeme kancane (Ukuphakama Okumaphakathi)

Uma inani le-CRP liphakathi kuka-1.0 mg/dL no-10.0 mg/dL , silibheka njengeliphakeme ngokulingene. Umphumela onjengalona ungabonisa izimo ezifana nalezi:

• Ukuvuvukala kwesistimu, njenge -rheumatoid arthritis (RA) , i-systemic lupus erythematosus (SLE) , noma ezinye izimo zokuzivikela komzimba, kungathinta umzimba wonke.
• Ukuhlaselwa yinhliziyo / ukuhlaselwa yinhliziyo.
• I-Pancreatitis .
• Ukuvuvukala kwemithambo yegazi .

Uma inani le-CRP liphakanyisiwe kakhulu (ukuphakama okuphawuliwe)

Inani le-CRP elingaphezu kuka-10 mg/dL libhekwa njengeliphakeme kakhulu. Umphumela onjengalona ungase ubonise izimo ezilandelayo:

• Ukutheleleka okunamandla kwamagciwane.
• Ukutheleleka ngegciwane.
• I-vasculitis yesistimu (ukuvuvukala kwemithambo yegazi).
• Ukulimala okukhulu/ukuhlukumezeka.

Uma inani le-CRP liphezulu kakhulu (ukuphakama okukhulu)

Uma inani le-CRP lingaphezu kuka-50 mg/dL , kubhekwa njengokuphakama okukhulu kakhulu.Amazinga aphezulu kakhulu e-CRP, ikakhulukazi uma edlula ku-50 mg/dL, ahlotshaniswa nokutheleleka okunamandla kwamagciwane cishe ku-90% wamacala. Lokhu kusho ukuthi uma inani eliphakeme kangaka litholakala, udokotela uzosola ngokuqinisekile ukutheleleka kwamagciwane futhi aqale ukuhlolwa nokwelashwa okudingekayo.

Kusho ukuthini ukuthi inani eliphansi le-CRP lisho ukuthini?

Ngakho-ke kusho ukuthini i-CRP ephansi? Sibone ukuthi izinga le-CRP elijwayelekile lingaphansi kuka-0.9 mg/dL. Ngakho-ke, ayikho into efana nezinga eliphansi. Lokho kusho ukuthi, uma inani lakho le-CRP liphuma licishe libe ngu-0.5 mg/dL, lokho kuhle kakhulu, kuvamile.

Kodwa-ke, uma izinga lakho le-CRP beliphezulu ngaphambilini futhi lehlile esivivinyweni samanje, lokho kuyisibonakaliso esihle kakhulu! Kusho ukuthi ukuvuvukala emzimbeni wakho kuyehla, noma ukuthi ukwelashwa kokuvuvukala kuphumelele. Udokotela wakho uzojabula ngalokho futhi.

Ingabe kufanele ngikhathazeke uma izinga lami le-CRP lingajwayelekile?

Ungase ukhathazeke kancane uma ubona ukufundwa kwe-CRP okuphezulu embikweni wakho. Ungase ucabange, "O, ingabe nginokuthile okungathi sína?" Kodwa, ukufundwa kwe-CRP okuphezulu akusho ngaso sonke isikhathi ukuthi unesifo esingathi sína esidinga ukwelashwa , ikakhulukazi uma ukufundwa kuphakeme kancane.

Khumbula ukuthi ngishilo ngaphambilini ukuthi ukubhema, ukulimala okuncane, kanye nezinye izimo zempilo ezivamile (njengokukhulelwa) nakho kungabangela ukwenyuka kwamazinga e-CRP. Ngezinye izikhathi, imiphumela ingathinteka ngamaphutha amancane ekuqoqweni kwegazi, ekuhlolweni kwelabhorethri, noma ngisho nasekuhlolweni.

Ngakho-ke, ungasheshi ufinyelele iziphetho wedwa uma ubona umphumela ongavamile. Ungesabi. Udokotela wakho uzobuyekeza umbiko wakho, awuqhathanise nezimpawu zakho, awuqhathanise nomlando wakho wezokwelapha, bese enza ezinye izivivinyo uma kudingeka ukuze athole ukuthi yini ngempela engalungile.

Ngezinye izikhathi, cishe oyedwa kubantu abangu-20 abaphilile angase abe nemiphumela engaphezu kwejwayelekile. Ngakho-ke, ungesabi ukukhuluma nodokotela wakho. Buza yonke imibuzo onayo. Uzokusiza futhi akunike isiqondiso esidingekayo.

Izinto okudingeka sizikhumbule (Umyalezo Wokuya Ekhaya)

Kulungile, ake siphinde sixoxe ngamanye amaphuzu abaluleke kakhulu esikhulume ngawo kulolu vivinyo lwe-CRP:

• I-CRP iyiprotheni ekhiqizwa yisibindi. Iyanda egazini uma kukhona ukuvuvukala emzimbeni.
• Lokhu kuhlolwa kungasiza ekutholeni izifo kanye nezimo zokuvuvukala njenge-arthritis , futhi kungasiza nasekunqumeni ukuthi ukwelashwa kuyasebenza yini.
• Ngisho noma izinga le-CRP liphakeme, lona lodwa alikwazi ukusho ukuthi yisiphi isifo noma ukuthi sitholakala kuphi. Kungase kudingeke ukuhlolwa okwengeziwe.
• Inani elijwayelekile le-CRP lingaphansi kuka-0.9 mg/dL (noma u-1.0 mg/dL).
• Amazinga e-CRP angakhuphuka kancane ngenxa yezici ezifana nokubhema, ukukhulelwa, ukulimala okuncane, kanye nokukhuluphala ngokweqile.
• Ungesabi uma ubona inani eliphezulu le-CRP.Khuluma nodokotela wakho bese uthola iseluleko. Uzoba umuntu ongcono kakhulu wokukuqondisa.

Ngakho-ke, ngithemba ukuthi usuphendule imibuzo eminingi owawunayo mayelana nokuhlolwa kwe-CRP. Ngithemba ukuthi lolu lwazi luzoba wusizo kuwe. Njalo nakekela impilo yakho, ngoba impilo iyingcebo enkulu kakhulu!

Ukuhlolwa kwe- CRP, i-C-Reactive Protein, Ukuvuvukala, Ukutheleleka, Ukuhlolwa Kwegazi, Impilo, Izimpawu, Isibindi, Ukungavikeleki Emzimbeni