Ingabe ubhekene nokungezwani komzimba okungavamile nenyama ebomvu? Ake sifunde nge-Alpha-gal Syndrome!

Wake wazibuza ukuthi kungani ungase ube nezimpawu zokungezwani komzimba ngemva kokudla inyama ebomvu njengenyama yenkomo, ingulube, noma imbuzi? Mhlawumbe uzothola ukuqubuka, noma uzothola isisu esibuhlungu, noma uzoba nenkinga yokuphefumula. Kungase kuzwakale kungavamile, kodwa empeleni kungenzeka. Namuhla sizokhuluma ngokungezwani komzimba okungavamile, kodwa okubaluleke kakhulu. Kubizwa ngokuthi i-Alpha-gal Syndrome.

Iyini i-Alpha-gal Syndrome? Masiyiqonde kalula!

Kalula nje, i-Alpha-gal Syndrome (AGS) uhlobo lokungezwani kokudla olunzima nolungavamile oluvela uma udla inyama ebomvu evela ezincelisayo (isibonelo, inyama yenkomo, ingulube, imbuzi, inyamazane). Kuvame ukuvela ngemva kokulunywa yizinhlobo ezithile zama-tick, ikakhulukazi uma uke walunywa izikhathi eziningana. Njengoba wazi, ama-tick ayizinambuzane ezincane ezinamathela ezilwaneni futhi zimunce igazi lazo.

Bheka manje, amanye ama-tick ane-molecule yama-carbohydrate ebizwa ngokuthi i-alpha-gal ematheni awo. Uma le molecule ye-alpha-gal ingena egazini lethu ngemva kokulunywa yi-tick, ingenza umzimba wethu uzwele kakhulu enyameni ebomvu. Okwenzekayo ukuthi amasosha ethu omzimba aqaphela inyama ebomvu njengento eyingozi emzimbeni bese eqala ukusabela ngokumelene nayo. Njengesitha. Yilokho okubangela lezo zimpawu zokungezwani komzimba. Abantu abane-AGS bangaba ne-allergy hhayi enyameni ebomvu kuphela, kodwa nakweminye imikhiqizo equkethe i-alpha-gal, isibonelo, eminye imithi kanye nensipho.

Ngeshwa, okwamanje alikho ikhambi le-AGS. Kodwa ungakhathazeki. Ungasebenzisana nodokotela wakho ukuthola izindlela zokugwema izimbangela futhi uhlale uphilile.

Iyini le molekyuli ebizwa ngokuthi i-Alpha-gal?

I-Alpha-gal iyi-carbohydrate, noma i-molecule kashukela, etholakala emangqamuzaneni ezilwane eziningi ezincelisayo. Kodwa ayikhiqizwa ngokwemvelo emzimbeni womuntu. Yingakho imizimba yethu iphatheka kabi uma ilunywa yi-tick.

Yikuphi ukudla nemikhiqizo equkethe i-Alpha-gal?

Izinto ezingase ziqukethe i-Alpha-gal zifaka:

• Inyama ebomvu: Izinto ezifana nengulube, inyama yenkomo, unogwaja, imvu, imbuzi, inyathi, kanye nenyama yenkomo.
• Imikhiqizo yezokwelapha kanye nemithi: Isibonelo, umuthi i-Cetuximab, osetshenziselwa umdlavuza.
• Imikhiqizo eyenziwe ngezilwane ezincelisayo: i-gelatin, ubisi lwenkomo, kanye nezinye izinsipho, okhilimu, nezinto zasekhaya zingase zibe nalezi zinto.

Cabanga nje, ngisho ne-ayisikhilimu noma ushizi owudlayo ungase ube nenani elincane lale alpha-gal. Ngakho-ke kufanele uqaphele kakhulu.

Futhi, abanye abantu abane-AGS bangase basabele emikhiqizweni equkethe into ebizwa ngokuthi i-carrageenan. I-Carrageenan iyinto evame ukusetshenziselwa ukujiya nokugcina ukudla. Ingatholakala ezintweni ezifana nobisi lwamantongomane, imikhiqizo yenyama, kanye neyogathi.

Ubani ongaba ne-Alpha-gal Syndrome?

Lokhu kungenzeka kunoma ubani, ngisho nomuntu ongakaze abe ne-allergy enyameni ebomvu ngaphambili. Kodwa-ke, kuvame ukubonwa kubantu abadala.

Abantu abachitha isikhathi esiningi ezindaweni ezingaphandle lapho kuvame khona imikhaza, njengasezindaweni ezinamahlathi kanye nezindawo ezinamahlathi, basengozini enkulu yokuthola i-AGS. ESri Lanka, kuhle futhi ukuthi labo abasebenza ezindaweni ezifana namahlathi noma amapulazi lapho kukhona khona izilwane baqaphele lokhu.

Hlobo luni lwemikhaza ebangela i-AGS?

E-United States, i-lone star tick yilona gciwane elivame kakhulu elihlotshaniswa ne-AGS. Kodwa-ke, kunezinye izinhlobo ze-tick ezingayibangela ezingxenyeni ezahlukene zomhlaba. Isibonelo:

• I-Blacklegged tick eMelika
• "I-Cayenne tick" eMelika Ephakathi
• I-tick yase-Asia enezimpondo ezinde e-Asia

Into ebaluleke kakhulu ukuqaphela uma ulunywa yinoma yimuphi umkhaza bese ucela iseluleko sezokwelapha uma kudingeka.

Ingabe akhona amanye amagama alesi sifo se-Alpha-gal?

Yebo, lokhu kunamanye amagama amaningana:

• Ukungezwani komzimba kwe-alpha-gal
• Ukungezwani nenyama yezilwane ezincelisayo
• Ukungezwani nenyama ebomvu
• Ukungezwani komzimba nenyama eluma ngamathe

Yini ebangela i-Alpha-gal Syndrome? Kungani lokhu kwenzeka?

Lesi simo saqala ukuchazwa ngo-2009. Sibangelwa ukulunywa yizimpukane ezithwala i-molecule ebizwa ngokuthi i-alpha-gal ematheni azo. Nakuba ezinye izinto eziningi zokungezwani nokudla zibangelwa amaprotheni, lesi sibangelwa i-molecule yama-carbohydrate (ushukela), ngakho-ke kuthatha isikhathi ukuthi ukusabela kubonakale. Lokho kusho ukuthi izimpawu zivame ukuvela phakathi kwamahora amabili kuya kwayisithupha ngemva kokudla inyama ebomvu . Lokhu kucatshangwa ukuthi kungenxa yokuthi imizimba yethu ithatha isikhathi eside ukugaya ama-carbohydrate kunamaprotheni.

Odokotela abasazi kahle ukuthi kungani le alpha-gal ibangela ukuzwela enyameni ebomvu noma umuthi womdlavuza oshiwo ngenhla i-Cetuximab. Ngokufanayo, ukuthi kungani abanye abantu beba ne-AGS kanti abanye bengenayo kusaphenywa.

Ziyini izimpawu ze-Alpha-gal Syndrome?

Izimpawu zalokhu zingahluka kakhulu. Abanye abantu bangase babe nezimpawu ezincane kakhulu, kanti abanye bangase babe nezimpawu ezinzima nezisongela ukuphila.

Ukusabela kwesikhumba okuvame kakhulu yile:

• Ukulunywa okukhulu kwesikhumba (odokotela bakubiza ngokuthi ukuqunjelwa)
• Ukubomvu kwesikhumba kanye nokuvuvukala (okubizwa nangokuthi ukushaqeka)
• Ukuqubuka kwesikhumba, amabhamuza abukeka njenge-chickenpox (lokhu kubizwa ngokuthi i-urticaria noma ama-hives)
• Ukuvuvukala kwezindebe, izinkophe, umphimbo, ulimi, noma ubuso (lokhu kubizwa ngokuthi i-angioedema)

Izinkinga zesistimu yokugaya ukudla nazo zingavela, ngezinye izikhathi lezi kuphela:

• Ubuhlungu besisu, ubuhlungu besisu
• Uhudo
• Isilungulela, ukungagayi kahle kokudla
• Ukungagayi kahle ukudla, ukungagayi kahle ukudla (dyspepsia)
• Ukuqaqamba kwemisipha
• Isicanucanu noma ukuhlanza

I-Alpha-gal syndrome ingabangela nezimpawu ezihlobene namaphaphu. Lezi ziyingozi kakhulu:

• I-Anaphylaxis: Lena yisifo esiyingozi kakhulu. Ukusabela okubi kakhulu kwe-allergy okungavimbela ukuphefumula futhi kube yingozi empilweni. Uma unenkinga yokuphefumula, iya esibhedlela esiseduze ngokushesha noma ushayele u-911.
• Ukukhwehlela
• Ubunzima bokuphefumula, ukushoda kokuphefumula (ukuphelelwa umoya)
• Ukuphefumula

Kungase kube nezinye izimpawu:

• I-Arthritis (lokhu akuvamile kakhulu)
• Ukushaya kwenhliziyo, uzizwa sengathi isifuba sakho siyashaya
• Umfutho wegazi ophansi (i-hypotension)
• I-Mast cell activation syndrome, isifo esingavamile sokuzivikela komzimba (futhi esingavamile)

Zikhona yini ezinye izinto ezithinta izimpawu?

Yebo, izimpawu zakho zingashintsha ngokuhamba kwesikhathi. Ukusabela kokungezwani komzimba kungaba kubi kakhulu noma kwenzeke kaningi uma ulunywe yi-tick entsha. Kwezinye izimo, izinto ezifana nokuphuza utshwala, umsebenzi womzimba, kanye nokuzivocavoca kungathinta nendlela umzimba wakho osabela ngayo ku-alpha-gal.

Kungani kunzima kangaka ukuxilonga i-Alpha-gal Syndrome?

Lokhu kungaba nzima kancane ukukubona. Kunezizathu eziningana.

Esinye ukuthi amakhizane awazizwa ubuhlungu lapho eluma, ngakho abantu abaningi abazi nokuthi balunywe yikhizane.

Futhi, ngokungafani nezinye izifo zokudla, ukusabela ku-alpha-gal kuthatha amahora amaningi ukuze kuvele . Ngezinye izikhathi izimpawu zivela phakathi kobusuku ngemva kwesidlo sakusihlwa. Ubani ongacabanga ukuthi kungenxa yenyama abayidlile ekuseni noma emini?

Futhi, akuwona wonke umuntu ophuza i-alpha-gal, lapho kuvela khona ukusabela, futhi izimpawu aziveli ngendlela efanayo ngaso sonke isikhathi.

Ngenxa yalezi zici, kungaba nzima kancane kuwe nakudokotela wakho ukuthola ukuthi lokhu kuyinto ehlukile yini ngaphandle kwe-alpha-gal.

Odokotela bakuthola kanjani lokhu?

Ukuze kutholakale i-AGS, udokotela wakho noma udokotela wakho we-allergy uzohlola ngokucophelela izimpawu zakho, umlando wezokwelapha, kanye nokuhlolwa komzimba. Ngaphezu kwalokho, ukuhlolwa kokungezwani komzimba kungenziwa ukuqinisekisa ukuxilongwa. Okuyinhloko kufaka phakathi:

• Ukuhlolwa kwegazi: Lokhu kuhlola ukuba khona kwama-antibodies e-immunoglobulin-E (IgE) egazini, amasosha omzimba ethu awenza ngokumelene ne-alpha-gal.
• Ukuhlolwa kokuhlatshwa kwesikhumba: Kulokhu, inani elincane le-allergen libekwa ebusweni besikhumba ukuze kubonakale ukuthi kukhona yini ukusabela.

Uma ucabanga ukuthi ungaba ne-AGS, bona udokotela ngokushesha okukhulu. Uma usheshe uyibone, kuba lula ukugwema izinto ezibangela ukungezwani komzimba nokuvimbela izinkinga.

Ingabe ikhona ikhambi eliphelele lalokhu?

Njengoba kushiwo ngaphambili, okwamanje alikho ikhambi le-Alpha-gal Syndrome. Kodwa ungakhathazeki. Uma itholakale kusenesikhathi, wena nodokotela wakho ningasebenzisana ukwakha uhlelo lokuphatha olufanela izidingo zakho.

Kuphathwa kanjani lokhu?

Ukwelashwa okuyinhloko komuntu one-AGS ukugwema ngokuphelele ukudla nemikhiqizo equkethe i-alpha-gal . Ngaphezu kwalokho, imithi inikezwa ukulawula izimpawu uma into efana nale igwinywe ngengozi.

Odokotela bangase batuse imithi efana nama-antihistamine noma i-adrenaline injector ukuze isetshenziswe ngokuphuthumayo. Ezimweni ezimbi kakhulu njenge-anaphylaxis, lo mjovo we-epinephrine ungasindisa impilo. Ezinye izindlela zokwelapha zincike ezimpawini zakho. Isibonelo, isixazululo se-cromolyn somlomo singasiza ngezinkinga zokugaya ukudla.

Ngingayinciphisa kanjani ingozi yokuthola i-Alpha-gal Syndrome?

Indlela engcono kakhulu yokuzivikela hhayi nje kuphela ezifweni ezibangelwa yizintwala, kodwa nakwezinye izifo ezithwalwa yizintwala, ukugwema ukulunywa yizintwala . Kunezinto eziningana ongayenza ukuze wenze lokhu:

• Gwema izindawo lapho kukhona khona amakhizane: Gwema ukuhamba ngokungadingekile emahlathini, ezindaweni ezinotshani, nasezindaweni ezinezihlahla eziningi, ikakhulukazi lapho kukhona khona izilwane. Qaphela futhi lapho usebenza engadini.
• Mboza kahle: Gqoka izingubo ezinemikhono emide, amabhulukwe amade. Beka amasokisi phezu kwebhulukwe lakho, gqoka izicathulo. Uma kungenzeka, sebenzisa isigqoko namagilavu.
• Sebenzisa izinto zokuxosha izinambuzane: Sebenzisa into yokuxosha izinambuzane evunyelwe ngokwezokwelapha. Eminye ingafakwa ezingutsheni. Imikhiqizo equkethe i-permethrin ingafakwa ezingutsheni.
• Hlola ama-ticks (Hlola ama-ticks):Ngemva kokubuya ngaphandle, hlola wena nezilwane zakho ezifuywayo ukuthi azinawo yini amakhizane. Kungumqondo omuhle futhi ukugeza.
• Uma ubona ikhikhi, yisuse ngokushesha: Sebenzisa ama-tweezers ukuze ubambe ikhanda noma umlomo wekhikhi, bese uyidonsela phezulu ngokucophelela ngaphandle kokuyichoboza. Bese ufaka umuthi wokubulala amagciwane endaweni.

Uma une-Alpha-gal Syndrome, yikuphi ukudla, iziphuzo, nemikhiqizo okufanele uyigweme?

Abantu abaningi abane-AGS kudingeka bagweme ngokuphelele inyama ebomvu nemikhiqizo yenyama ebomvu. Kodwa-ke, akuwona wonke umuntu osabela ngendlela efanayo ku-alpha-gal. Ngakho-ke kungcono ukukhuluma nodokotela wakho noma udokotela wezifo zokungezwani komzimba ukuze uthole ukuthi yini ngempela ekubangelayo.

Izinto okufanele uzigweme ngokuvamile yilezi:

• Inyama ebomvu: inyama yenkomo, iwundlu, imbuzi, inyamazane, unogwaja, inyathi, ingulube.
• Imikhiqizo eyenziwe ngenyama ebomvu: izithasiselo zokudla, ubisi, ukhilimu, i-ayisikhilimu, amafutha ezilwane (inyama yengulube), ushizi.
• Imikhiqizo yokunakekela isikhumba eyenziwe ngenyama: imikhiqizo equkethe i-collagen, i-lanolin, i-gelatin, i-glycerin.
• Eminye imikhiqizo: Khuluma nodokotela wakho nganoma yimiphi imithi oyithathayo. Futhi, ama-valve enhliziyo avela ezingulubeni noma ezinkomeni, i-mesh yokuhlinzwa, kanye neminye imijovo kungabangela ukusabela kokungezwani komzimba.

Kuzokwenzekani ngokulandelayo? Sizophila kanjani nalokhu?

Uma ulandela imiyalelo kadokotela wakho ngokucophelela futhi ugwema izinto ezibangela ukungezwani komzimba kwakho, ungaphila kahle ne-AGS. Udokotela wakho uzokusiza ukuthola izindlela zokunciphisa ingozi yakho yokungezwani komzimba.

Into ebaluleke kakhulu ukuthatha izinyathelo zokugwema ukulunywa yizikhakhane , njengoba ukulunywa yizikhakhane okuphindaphindiwe kungenza ukusabela kokungezwani komzimba kube kubi kakhulu.

Kufanele ufune nini iseluleko sezokwelapha?

Uma uba nezimpawu ze-AGS, bheka udokotela wezifo ezibangelwa ukungezwani komzimba noma udokotela ojwayelekile ngokushesha ukuze kwakhiwe uhlelo lokwelashwa olufanele wena.

Umlayezo Wokuya Nawe Ekhaya

Kulungile, ngakho-ke i-Alpha-gal Syndrome (AGS) esikhulume ngayo namuhla iwukusabela okukhulu kokungezwani komzimba nenyama ebomvu okubangelwa ukulunywa yizimpukane. Kungaba nzima kancane ukuyixilonga, njengoba izimpawu zivela emahoreni kamuva. Futhi okwamanje akukho ukwelashwa kwayo.

Kodwa ungakhathazeki! Uma ukuqaphela kusenesikhathi, ulandele iseluleko sikadokotela wakho, ugweme ukudla nemikhiqizo eyingozi, futhi uzivikele ezifweni zama-tick, nawe ungahlala uphilile futhi uphilile. Uma unalezi zimpawu, qiniseka ukuthi ubona udokotela.

'I-Alpha-gal Syndrome, Ukungezwani komzimba nenyama ebomvu, Izifo ezithwalwa yizimpukane, Ukungezwani kokudla, Izimpawu zokungezwani komzimba, Ukuvikelwa ezimpukaneni