Sonke siyazi ukuthi amangqamuzana amhlophe egazi emizimbeni yethu afana namasosha asivikela ezifweni. Kodwa cabanga, kwenzekani uma lawa maseli avikelayo, abizwa ngokuthi ama-histiocytes, ekhula kakhulu emizimbeni yethu? Yilapho inkinga iqala khona. Lawa maseli angaqoqana futhi akhe amathumba nezilonda ezingxenyeni ezahlukene zomzimba. Namuhla sikhuluma ngesifo esingavamile esikhula kanje.
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Kuyini i-LCH (i-Langerhans cell histiocytosis)?
Kalula nje, i-LCH (i-Langerhans Cell Histiocytosis) yisimo esingavamile esifana nezinhlobo ezithile zomdlavuza. Kulesi simo, uhlobo lweseli lokuzivikela elibizwa ngokuthi ama-Langerhans lukhula ngokungalawuleki futhi luqongelela ezingxenyeni ezahlukene zomzimba.
Lesi sifo sivame ukubonakala ezinganeni ezincane nasezinsaneni , kodwa singavela nakubantu abadala. Nakuba ngezinye izikhathi kucatshangwa ukuthi umdlavuza, empeleni awuwona umdlavuza. Kodwa-ke, selashwa odokotela bezifo zomdlavuza. Ngakho-ke ungakhathazeki. Ake sibheke lokhu kabanzi.
Ziyini izimpawu zalesi sifo?
I-LCH ingathinta noma yisiphi isitho emzimbeni. Isibonelo, ingathinta amaphaphu, isibindi, ubuchopho, ubende, noma ama-lymph node. Kodwa-ke, izimpawu ezivame kakhulu zibonakala esikhumbeni nasemathanjeni.
Abanye abantu bangase babe nezimpawu ezincane kakhulu futhi babe ngcono ngokwabo ngaphandle kokwelashwa. Kodwa-ke, kwabanye, kungaba yisimo sesikhathi eside esithinta izingxenye eziningi zomzimba.
Ake sibheke ithebula elingezansi ukuze sibone ukuthi yiziphi izimpawu ezivezwa yi-LCH uma ithinta izingxenye ezahlukene zomzimba.
| Ingxenye yomzimba ethintekile | Izimpawu ezingabonakala |
|---|---|
| Amathambo | Ngokuvamile ukuvuvukala noma amaqhubu abuhlungu (ama-granuloma) kwakheka ekhanda nakwamanye amathambo. Lokhu kungabangela ubuhlungu emathanjeni, ukuvuvukala, futhi ngezinye izikhathi ngisho nokuphuka kwamalungu. |
| Isikhumba | Amaqhubu abomvu, anamaqhubu esikhumbeni (isib. emakhwapheni, emaqakaleni). Izingane zingase zibe namaqhubu abomvu, anamaqhubu ekhanda. Lokhu ngezinye izikhathi kungaphambaniswa nesigqoko sokubeletha, okuyisimo esivamile. |
| Isibindi | Isibindi sivame ukuthinteka ezimweni ezimbi kakhulu zesifo. Izimpawu zifaka phakathi ukuphuzi kwesikhumba (i-jaundice) kanye nesikhathi eside sokuba igazi lijiye. |
| Ama-Lymph Node | Ukuvuvukala kwezindlala ngemuva kwezindlebe, entanyeni, nakwezinye izindawo. Ngaphezu kwalokho, kungase kube nobunzima bokuphefumula nokukhwehlela. |
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Check Availability →Indlela yokuxilonga lesi sifo ngokunembile?
Uma udokotela wakho esola lesi sifo, kuzodingeka enze i-biopsy ukuqinisekisa ukuthi sitholakale. Lokhu kuhilela ukuthatha ingxenye encane kakhulu yezicubu endaweni esolisayo bese ihlolwa ngaphansi kwe-microscope ngudokotela wezifo. Lokhu kuzobheka amaprotheni athile kanye nezinye izimpawu eziqondene nesifo.
Ngaphezu kwalokho, udokotela wakho angase acele ukuhlolwa okwengeziwe kuye ngezimpawu zakho.
- Ukuhlolwa kwe-X-ray: Hlola isimo samaphaphu akho namathambo.
- Ukuhlolwa kwe-bone marrow: Ukuhlolwa kwamaseli e-LCH emnkantsheni wethambo.
- Ukuhlolwa kwamakhemikhali egazi: Hlola ukusebenza kwezinso, isibindi, indlala yegilo kanye nesistimu yomzimba yokuzivikela.
- I-MRI, i-PET, kanye ne-CT scans: Thola izithombe ezinemininingwane zangaphakathi lomzimba.
- Ukuhlolwa komchamo: Hlola amazinga amangqamuzana abomvu namhlophe, amaprotheni, kanye noshukela emchameni.
Yini ebangela i-LCH?
Asikazi kahle ukuthi kungani abanye abantu beba ne-LCH. Kodwa kutholakale ukuthi cishe ingxenye yabantu abanalesi sifo banezakhi zofuzo ezinephutha ezibangela ukuba amaseli e-Langerhans akhule ngokungalawuleki. Okubalulekile ukuthi lolu shintsho lwezakhi zofuzo (ukuguqulwa kwezakhi zofuzo) lwenzeka ngemva kokuzalwa. Lokhu kusho ukuthi akusona isifo esizuzwe njengefa kubazali .
Ngaphezu kwalokho, abacwaningi basola ukuthi ezinye izici eziningana zingathonya lokhu:
- Ukubhema.
- Ukuchayeka kwabazali ebuthi obungokwemvelo njenge-benzene noma uthuli lwezinkuni.
- Ukutheleleka esikhathini sokuzalwa.
- Ukuba nomlando womndeni wesifo se-thyroid.
Yiziphi izindlela zokwelapha lokhu?
Ukwelashwa ngamakhemikhali ngezinye izikhathi kusetshenziswa ukwelapha i-LCH, njengoba kusetshenziswa ukwelapha ezinye izinhlobo zomdlavuza. Ngakho-ke, abantu abaningi abanalesi sifo banakekelwa odokotela bezifo zomdlavuza kanye nodokotela begazi.
Kodwa khumbula, ngokungafani nomdlavuza, izinhlobo ezilinganiselwe ze-LCH ngezinye izikhathi ziyaphela zodwa ngaphandle kokwelashwa.
Ake sibone ukuthi yiziphi izinketho zokwelapha ezitholakala kuthebula elingezansi.
| Indlela yokwelapha | Incazelo elula |
|---|---|
| Ukwelashwa ngamakhemikhali | Ukunikeza imithi yokubhubhisa amangqamuzana agulayo. |
| Ukwelashwa ngemisebe | Imisebe ephansi ithunyelwa engxenyeni yomzimba ethintekile yilesi sifo kuphela. |
| Ukuhlinzwa | Ukususwa kwezimila noma izilonda ezibangelwa yi-LCH ngokuhlinzwa. |
| Ama-steroid | Ukunikeza ama-steroid noma eminye imithi yokulwa nokuvuvukala njenge-prednisone. |
| Ukwelashwa ngokukhanya kwe-UV | Ukwelashwa kwezifo zesikhumba kusetshenziswa ukukhanya okukhethekile. |
| Ukufakelwa kweseli lesiqu | Indlela yokwelapha ecatshangelwa ezimweni ezinzima kakhulu. |
Iningi labantu abane-LCH liyalulama ngemva kokwelashwa. Uma lesi sifo sithinte ubende, isibindi, noma umongo wakho, sibizwa ngokuthi 'i-LCH enobungozi obukhulu'. Ngisho nakulesi simo, cishe abantu abangu-80% bayalulama ngokugcwele . Ngakho-ke kubalulekile ukuhlala unethemba.
Umlayezo Wokuya Nawe Ekhaya
- I-LCH yisifo esingavamile. Akuyona umdlavuza ngokwawo, kodwa iphathwa ngendlela efanayo nomdlavuza.
- Nakuba lokhu kuvame ukubonakala ezinganeni ezincane, kungavela kunoma ubani wanoma yimuphi ubudala.
- Uma unezimpawu ezifana nezilonda zesikhumba, ubuhlungu emathanjeni, noma ukuvuvukala, ungazinaki.
- Uma wena noma ingane yakho ninokungabaza ngalezi zimpawu, qinisekani ukubonana nodokotela wenu . Ningesabi futhi nizame ukuzixilonga ku-inthanethi.
- Ngokwelashwa okufanele, iningi leziguli ze-LCH liyalulama ngokugcwele. Ngakho-ke, kubaluleke kakhulu ukulandela iseluleko sezokwelapha esifanele.
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