Iyini i-cortisol? Iyithinta kanjani umzimba wakho?

Cishe uke wezwa igama elithi 'cortisol', ikakhulukazi uma kukhulunywa 'ngokucindezeleka'. Kodwa bewazi ukuthi akuyona nje 'i-hormone yokucindezeleka'? I-Cortisol iyi-hormone ebaluleke kakhulu emizimbeni yethu. Eqinisweni, ithinta cishe zonke izitho nezicubu emzimbeni wethu.

Iyini ngempela i-cortisol?

Kalula nje, i-cortisol iyi-hormone eyenziwe futhi ikhishwe yizindlala zakho ze-adrenal - izindlala ezimbili ezincane ezitholakala ngaphezu kwezinso zakho. Ingaphansi kwesigaba sama-hormone abizwa ngokuthi ama-glucocorticoids , angama-hormone e-steroid.

Ungase ucabange ukuthi lokhu kubalulekile kuphela ekucindezelekeni. Kodwa akunjalo. I-Cortisol ineminye imisebenzi eminingi ebalulekile okufanele iyenze. Isibonelo:

• Ilawula indlela umzimba wethu osebenzisa ngayo ushukela, noma i-glucose , ukuze uthole amandla.
• Kunciphisa ukuvuvukala emzimbeni.
• Ilawula umfutho wegazi.
• Kusiza ekulondolozeni umjikelezo wethu wokulala nokuvuka.

Umzimba wethu uhlala uqapha leli zinga le-cortisol, uligcina lisezingeni elizinzile, okungukuthi, lisesimweni se-homeostasis . Ngoba kungakhathaliseki ukuthi amazinga e-cortisol aphezulu noma aphansi, alilungile empilweni yethu.

Ngakho-ke ingabe i-cortisol ngempela 'iyi-hormone yokucindezeleka'?

Yebo, i-cortisol empeleni idlala indima ebalulekile ekusabeleni kwemizimba yethu ekucindezelekeni. I-Cortisol ikhishwa uma ubhekene nanoma yiluphi uhlobo lokucindezeleka, njengalokhu:

• Ukucindezeleka okukhulu - Cabanga ngakho njengokujaha inja ngokuzumayo.
• Ukucindezeleka okungapheli - isibonelo, izinkinga zomsebenzi eziqhubekayo noma izinkinga zomndeni.
• Ukucindezeleka okubuhlungu - njengokubhekana nesenzakalo esingenakucatshangwa.

Kodwa, njengoba ngishilo ngaphambili, i-cortisol inezinto eziningi kakhulu ezingenziwa kunokuthi nje isize ngokucindezeleka.

I-cortisol ithinta kanjani umzimba wami?

I-Cortisol ithinta cishe zonke izitho zomzimba emzimbeni wethu, futhi iyasiza nokulawula imisebenzi eminingana ebalulekile.

Ukulawula indlela imizimba yethu esabela ngayo ekucindezelekeni

Uma sicindezelekile, imizimba yethu iqala ikhiphe ama-hormone ahlobene nempendulo 'yokulwa noma yokubaleka' , njenge -adrenaline . Bese kukhishwa i-cortisol. Uyazi ukuthi kungani? Ukuze sihlale siqaphile. I-Cortisol iphinde isize isibindi sethu ukuthi sikhiphe i-glucose , okuyishukela. Yilokhu okusinika amandla ngokushesha ngezikhathi zokucindezeleka.

Ukwakheka kwe-metabolism kanye nokulawulwa koshukela egazini

Ukuguqulwa kwe-MetabolismKalula nje, yizo zonke izinqubo zamakhemikhali ezisisiza siphile futhi sisebenze ngaphakathi emizimbeni yethu. Izinkulungwane zalezi zinqubo zenzeka emizimbeni yethu ngaso sonke isikhathi.

I-Cortisol ithinta lo mshini wokusebenza kwe-metabolism ngokulawula indlela imizimba yethu esebenzisa ngayo i-glucose ukuze ithole amandla. Lokhu ikwenza ngezindlela eziningi. Isibonelo, i-cortisol itshela ama-pancreas ethu ukuthi anciphise ukukhiqizwa kwe-insulin futhi andise ukukhiqizwa kwe-glucagon . I-insulin yehlisa ushukela egazini, kanti i-glucagon inyusa ushukela egazini. Uyaqonda?

Akukhona lokho kuphela, i-cortisol ithinta nezinye izicubu eziningana emzimbeni wethu futhi ilawula ukusetshenziswa kwe-glucose. Phakathi kwazo:

• Izicubu zamafutha – okungukuthi, amafutha emzimbeni.
• Isibindi
• Imisipha

Ukuvimbela ukuvuvukala

Esikhathini esifushane, i-cortisol inganciphisa ukuvuvukala , okuwukuvuvukala nokubomvu emzimbeni, futhi ikhulise amasosha omzimba wethu. Kodwa-ke, uma umzimba wakho unezinga eliphezulu le-cortisol isikhathi eside, umzimba wakho uyajwayelana nakho. Okungenzeka ukuthi ukuvuvukala kuyanda futhi amasosha omzimba wakho abe buthaka.

Ukulawula umfutho wegazi

Akukacaci kahle ukuthi i-cortisol ilawula kanjani umfutho wegazi kubantu. Kodwa-ke, uma amazinga e-cortisol ephezulu kakhulu, ingaholela ekucindezelekeni kwegazi okuphezulu. Ngokufanayo, uma amazinga e-cortisol ephansi kakhulu, ingaholela ekucindezelekeni kwegazi okuphansi.

Ukusiza ukulawula umjikelezo wokulala nokuvuka

Iningi labantu linamazinga aphansi e-cortisol uma belala ebusuku. Amazinga e-cortisol aphakama ngaphambi nje kokuba bavuke ekuseni. Lokhu kukhombisa ukuthi i-cortisol ihlobene kakhulu nesigqi sethu se-circadian , okuyindlela imizimba yethu esebenza ngayo nendlela esivuka ngayo kuye ngesikhathi sosuku.

Umzimba wami ulawula kanjani amazinga e-cortisol?

Imizimba yethu inesimiso esiyinkimbinkimbi kakhulu sokulawula amazinga e-cortisol. I-hypothalamus yakho – ingxenye yobuchopho bakho – kanye ne-pituitary gland yakho – i-gland encane etholakala phansi kobuchopho bakho – isebenza ndawonye ukulawula ukukhiqizwa kwe-cortisol yizindlala zakho ze-adrenal. Nansi indlela esebenza ngayo:

• Uma amazinga e-cortisol egazini lakho ehla, i-hypothalamus ikhipha i -hormone ebizwa ngokuthi i-corticotropin-releasing hormone (CRH) .
• Lokhu kutshela i-pituitary gland yakho ukuthi yenze i-adrenocorticotropic hormone (ACTH) .
• I-ACTH bese iyahamba iyotshela izindlala zakho ze-adrenal ukuthi zenze futhi zikhiphe i-cortisol.

Ngakho-ke, ukuze ugcine amazinga e-cortisol aphilile, i-hypothalamus yakho, i-pituitary gland, kanye nezindlala ze-adrenal zonke kudingeka zisebenze kahle.

Yini ebangela amazinga aphezulu e-cortisol?

Uma unezinga eliphezulu le-cortisol emzimbeni wakho isikhathi eside ( i-hypercortisolism ), ivame ukubizwa ngokuthi i-Cushing's syndrome . Izinto ezingabangela amazinga aphezulu e-cortisol kanye ne-Cushing's syndrome zifaka:

• Ukuthatha imithamo ephezulu yemithi ye-corticosteroid , njenge- prednisone , i-prednisolone , kanye ne-dexamethasone .
• Izimila ezikhiqiza i-ACTH – Lezi zivame ukuvela endlaleni yakho ye-pituitary.
• Amathumba akheka ezindlaleni ze-adrenal futhi akhiqize i-cortisol eningi.

Ziyini izimpawu zamazinga aphezulu e-cortisol?

Uma amazinga e-cortisol ephakanyisiwe, okuyi -Cushing's syndrome, izimpawu ezifana nalezi:

• Ukukhuluphala, ikakhulukazi ebusweni nasesiswini.
• Amafutha ahlala emhlane phakathi kwamahlombe (njengenkunzi).
• Ukubonakala kwamabala okunwebeka abanzi, anombala onsomi esiswini.
• Ubuthakathaka bemisipha ezingalweni nasemathangeni angenhla.
• Ukwanda kwamazinga kashukela egazini kuvame ukuholela ku- Type 2 Diabetes Mellitus .
• Umfutho wegazi ophezulu.
• Kwabesifazane, ukukhula kwezinwele okungafuneki emzimbeni ( i-hirsutism ).
• Ubuthakathaka bamathambo ( i-osteoporosis ) kanye nokuqhekeka kwamathambo kungenzeka.

Bheka, ungesabi ngoba nje unesinye noma ezimbili zalezi zimpawu. Kodwa uma uzizwa sengathi unezinye zalezi zinto, kungcono ukubona udokotela.

Yini ebangela amazinga aphansi e-cortisol?

Odokotela babiza ukungasebenzi kahle kwe-adrenal, okwenzeka lapho amazinga e-cortisol ephansi kunokuvamile ( i-hypocortisolism ). Kunezinhlobo ezimbili zalokhu: okuyinhloko kanye nokwesibili.

Ukuntuleka kwe-adrenal okuyinhloko kuvame ukwenzeka lapho amasosha omzimba wakho ehlasela izindlala zakho ze-adrenal. Lokhu kubizwa nangokuthi isifo sika-Addison . I-Cortisol ingancipha futhi uma izicubu zezindlala ze-adrenal zitheleleka noma uma ukugeleza kwegazi kuzo kuvinjiwe.

Ukungasebenzi kahle kwe-adrenal yesibili kwenzeka lapho i-pituitary gland yakho ingasebenzi kahle ( i-hypopituitarism).) Yebo, uma unesimila se-pituitary. Lezi zimo zikhawulela ukukhiqizwa kwe -ACTH , okubuye kunciphise ukukhiqizwa kwe-cortisol. Futhi, uma usebenzisa umuthi we-corticosteroid bese uyeka ngokuzumayo, amazinga akho e-cortisol angehla.

Ziyini izimpawu zamazinga aphansi e-cortisol?

Uma amazinga e-cortisol ephansi, okuwukuntuleka kwe-adrenal , izimpawu ezifana nalezi:

• Ukuzizwa ukhathele futhi ukhathele njalo (Ukukhathala).
• Ukwehlisa isisindo ngokungahlosile.
• Ukulahlekelwa yisifiso sokudla.
• Umfutho wegazi ophansi.

Kufanele ngimbone nini udokotela mayelana namazinga ami e-cortisol?

Uma unezimpawu ezibonisa ukuthi unesifo sikaCushing noma ukungasebenzi kahle kwe-adrenal , qiniseka ukuthi ubona udokotela wakho. Ungalibali.

Futhi, uma unenkinga yokucindezeleka kwansuku zonke, khuluma nodokotela wakho ngezindlela zokukulawula. Ungase uthole usizo.

Ngingawehlisa kanjani amazinga ami e-cortisol?

Uma unesifo esifana ne -Cushing's syndrome , uzodinga ukwelashwa ukuze wehlise amazinga akho e-cortisol. Lokhu kuvame ukuhilela imithi noma ukuhlinzwa.

Kodwa-ke, kunezindlela eziningana zokusiza ukulawula amazinga ethu e-cortisol ngokujwayelekile, ikakhulukazi lapho amazinga e-cortisol enyuka ngenxa yokucindezeleka:

• Lala kahle futhi uphumule ebusuku. Izinkinga ezifana nokungalali kahle nokusebenza ebusuku zingandisa amazinga e-cortisol. Zama ukulala okungenani amahora angu-7-8 ngosuku.
• Ukunyakazisa umzimba wakho nokuzivocavoca. Ukuzilolonga njalo kuthuthukisa ubuthongo futhi kunciphisa ukucindezeleka. Ukuhamba okungenani imizuzu engama-30 ngosuku nakho kuhle.
• Yenza izivivinyo zokuphefumula okujulile. Izivivinyo zokuphefumula ezilawula ukuphefumula kwakho zivuselela uhlelo lwethu lwezinzwa olune-parasympathetic - uhlelo lwethu 'lokuphumula nokugaya'. Lokhu kusiza ukunciphisa amazinga e-cortisol.
• Jabula, hleka. Uma uhleka, ama-endorphin , ama-hormone enjabulo, ayakhishwa, futhi amazinga e-cortisol ayancishiswa. Ukuhlanganyela emisebenzini ejabulisayo nakho kuthuthukisa inhlalakahle yengqondo.
• Gcina ubudlelwano obuhle nobunempilo. Ubudlelwano obuhlala buyinkinga futhi bucindezela buvame ukuholela ekucindezelekeni. Ngakho-ke, kubalulekile ukugcina ubudlelwano obuhle nabangani nomndeni omuhle.

Ekugcineni, umyalezo okufanele uwuthathe uye ekhaya:

Uma abantu bezwa igama elithi cortisol, bacabanga ukuthi kuyinto embi. Kodwa empeleni iyi-hormone ebalulekile ethinta izici eziningi zemizimba yethu.Kunezindlela eziningi zokusiza ukunciphisa ukucindezeleka nokulawula amazinga ethu e-cortisol. Kodwa-ke, ngezinye izikhathi amazinga e-cortisol angaba phezulu noma aphansi ngendlela engavamile, okuyinto esingenakuyilawula.

Uma unezimpawu zamazinga aphezulu noma aphansi e-cortisol, kubalulekile ukubona udokotela. Bangenza izivivinyo ezimbalwa ezilula ukuze bathole ukuthi izindlala zakho ze-adrenal noma i-pituitary gland yizo ezibangela lezi zimpawu. Khumbula, uma usheshe uzibambe, kuba lula ukuzelapha.

Ngakho-ke, nakekela umzimba wakho, futhi ungesabi ukufuna iseluleko sezokwelapha uma ubona noma yini engavamile noma ehlukile. Hlala uphilile!

I- Cortisol, ukucindezeleka, ama-hormone, izindlala ze-adrenal, i-Cushing's syndrome, isifo sika-Addison