Ingabe ngezinye izikhathi uke ucabange ukuthi, "Hawu Nkulunkulu wami, kungani ngikhula ngokushesha kangaka?" Noma ingabe ubuso bakho sebuyindilinga futhi kuvele iqhubu elincane lamafutha ngemuva kwentamo yakho? Mhlawumbe nawe uzizwa ukhathele futhi unesizungu ngaso sonke isikhathi. Uma unesinye noma ngaphezulu salezi zimpawu, isizathu kungaba ushintsho ezingeni le-cortisol ye-hormone emzimbeni wakho. Ngakho-ke namuhla, ake sixoxe nge-cortisol kanye nokuhlolwa okuyilinganisa ngokuningiliziwe, kalula.
Kalula nje, iyini i-cortisol?
I-Cortisol iyi-hormone ebalulekile emzimbeni wethu. Cabanga ngayo njenge-hormone eyinhloko "yokusabela ekucindezelekeni" emzimbeni wethu. Uma sicindezelekile noma singaphansi kwengcindezi, i-cortisol yiyona elungiselela umzimba wethu ukubhekana nayo. Ngaphezu kwalokho, le hormone inegalelo kweminye imisebenzi eminingi ebalulekile emzimbeni wethu.
- Ilawula umfutho wegazi.
- Kusiza ukugcina amazinga kashukela egazini.
- Ama-carbohydrate, amaprotheni, kanye nama-lipid ekudleni esikudlayo kusisiza ukuthi siwagaye abe amandla.
- Ilawula ukuvuvukala emzimbeni.
- Kuphinde kusize ngomjikelezo wokulala nokuvuka olawula ukulala kwethu nokuvuka kwethu.
Le hormone ye-cortisol ikhiqizwa yizindlala ezimbili ezincane ezitholakala ngaphezu kwezinso zethu. Lezi sizibiza ngokuthi izindlala ze-adrenal. Ngakho-ke uma kunenkinga ngalezi zindlala, noma ngendlala ye-pituitary phansi kobuchopho, amazinga e-cortisol angaba phezulu kakhulu noma aphansi kakhulu. Uma udokotela wakho ekubuza ngalezi zimpawu, angakucela ukuthi uhlole i-cortisol.
Ziyini izimpawu ze-cortisol ephezulu nephansi?
Uma amazinga e-cortisol eshintsha, imizimba yethu ithumela izimpawu ezahlukene. Ake sibone ukuthi ziyini lezi zimpawu. Ngizokukhombisa lokhu etafuleni ukuze ukuqonde kalula.
| Uma amazinga e-cortisol ephezulu (i-Cortisol ephezulu) | Uma amazinga e-cortisol ehla (i-Cortisol ephansi) |
|---|---|
| Ukukhuluphala okusheshayo (ikakhulukazi esiswini, esifubeni, nasebusweni) | Ukukhathala okuqhubekayo |
| Ubuso obuyindilinga | Isiyezi |
| Ukwakheka kweqhubu elinamafutha ngemuva kwentamo noma phakathi kwamahlombe | Ukwehlisa isisindo |
| Umfutho wegazi ophakeme | Umfutho wegazi ophansi |
| Amazinga kashukela egazini akhuphukile | Ubuthakathaka bemisipha |
| Izinguquko zesikhumba (ziphuka kalula, imicu ensomi) | Ukuhlanza, isicanucanu, kanye nobuhlungu besisu |
| Imijikelezo yokuya esikhathini engajwayelekile kwabesifazane | Ukunxanela usawoti emzimbeni |
Yiziphi izimbangela zokwanda kwe-cortisol?
Uma amazinga e-cortisol ephezulu kakhulu, leso simo sisibiza ngokuthi i-Cushing's syndrome . Kungaba nezizathu eziningana eziyinhloko zalokhu:
- Ukuthatha imithi eminingi yama-steroid (isib. i-prednisone) isikhathi eside ngenxa yezinye izifo.
- Isimila esise-pituitary gland ebuchosheni. Le gland yileyo "elawula" ezinye izindlala.
- Isimila esitholakala ezindlaleni ze-adrenal.
Yiziphi izimbangela ze-cortisol ephansi?
Isimo esiyinhloko esibangela amazinga aphansi e-cortisol yisifo sika-Addison . Lokhu kwenzeka lapho amasosha ethu omzimba ehlasela izindlala ze-adrenal. Ngaphezu kwalokho,
- Ukutheleleka noma ukulimala kwezindlala ze-adrenal.
- Indlala ye-pituitary ayisebenzi kahle.
- Ukuyeka ngokuzumayo umuthi we-steroid osetshenziswe isikhathi eside.
Okubalulekile: Uma usebenzisa noma yimuphi umuthi we-steroid, ungalokothi uyeke ukuwuthatha ngokuzumayo ngaphandle kweseluleko sikadokotela wakho.Ukwenza kanjalo kungabangela amazinga e-cortisol ehle ngokuzumayo, okubangela isimo esiyingozi.
Ukuhlolwa kwe-cortisol kwenziwa kanjani?
Kunezindlela ezintathu eziyinhloko zokuhlola amazinga akho e-cortisol: ukuhlolwa kwegazi, amathe, kanye nomchamo. Udokotela wakho uzokunikeza ukuhlolwa okufanele kakhulu ngokusekelwe ezimpawini zakho.
Amazinga e-Cortisol avame ukushintshashintsha phakathi nosuku, amazinga aphezulu ekuseni kakhulu kanti aphansi kakhulu phakathi nobusuku . Yingakho kudingeka kwenziwe ezinye izivivinyo ngezikhathi ezithile zosuku.
1. Ukuhlolwa Kwegazi le-Cortisol
Lesi yisilingo esivame kakhulu. Ngokuvamile senziwa kabili ngosuku.
- Eyokuqala: cishe ngo-8 ekuseni (lapho amazinga e-cortisol ephezulu kakhulu)
- Okwesibili: Cishe ngo-4 ntambama (lapho amazinga e-cortisol ehla khona)
Kulula kakhulu. Ilabhorethri ithatha isampula encane yegazi emthanjeni osengalweni yakho.
2. Ukuhlolwa kwe-Cortisol Saliva
Lena futhi indlela enembile kakhulu futhi elula. Lokhu kubaluleke kakhulu ekuxilongweni kwe-Cushing's syndrome. Udokotela uzokunikeza ikhithi encane.
- Lokhu kuvame ukwenziwa phakathi kuka-11 no-12 ebusuku , ngaphambi kokulala. Lokhu kungenxa yokuthi yilapho amazinga e-cortisol omuntu ophilile ephansi kakhulu. Uma amazinga esephezulu ngaleso sikhathi, kuyisibonakaliso senkinga.
- Kufanele ugweme ukudla, ukuphuza, noma ukuxubha amazinyo akho imizuzu engama-30 ngaphambi kokuhlolwa.
- Kufanele ubambe i-swab emlonyeni wakho cishe imizuzu emibili ukuze uqoqe amathe, bese uyibuyisela epayipini bese uyithumela elabhorethri.
3. Ukuhlolwa Komchamo we-Cortisol
Ngezinye izikhathi udokotela wakho uzokucela ukuthi uqoqe isampula yomchamo emahoreni angama-24.
- Okwenzekayo kulokhu ukuthi kufanele uqoqe isampula yomchamo ngamunye owudlulayo esikhathini samahora angama-24 ebhodleleni elikhethekile olinikwayo.
- Leli bhodlela kufanele ligcinwe esiqandisini noma ebhokisini elineqhwa.
- Uma amahora angama-24 esephelile, kufanele ithunyelwe elabhorethri.
Yiziphi ezinye izivivinyo ezikhethekile ezenziwayo?
Ngezinye izikhathi, kudingeka ukuhlolwa okwengeziwe ukuze kutholakale imbangela eqondile yamazinga akho e-cortisol angajwayelekile.
- Ukuhlolwa Kokukhuthaza I-ACTH: Lokhu kuhlola ukuthi izindlala zakho ze-adrenal zisabela kanjani ku-hormone ebizwa ngokuthi i-ACTH, evela ku-pituitary gland. Lokhu kuvame ukwenziwa lapho amazinga e-cortisol ephansi.
- Ukuhlolwa Kokucindezela I-Dexamethasone: Lokhu kufana nolunye uhlangothi lokuhlolwa olungenhla. Kwenziwa ukuthola imbangela yamazinga aphezulu e-cortisol. Lapha, kunikezwa inani elincane le-steroid elibizwa ngokuthi i-`Dexamethasone`, bese amazinga e-cortisol ahlolwa ngakusasa ekuseni.
Ngokusekelwe emiphumeleni yalezi zivivinyo, udokotela wakho anganquma ukuthi inkinga ikwindlala ye-pituitary, indlala ye-adrenal, noma okunye. Ngezinye izikhathi, uma kusolwa ukuthi kukhona isimila , kungacelwa ukuthi kwenziwe i-CT scan noma i-MRI scan .
Khumbula, izinga le-cortisol elingajwayelekile embikweni wokuhlolwa akulona njalo uphawu lokugula okukhulu. Amazinga e-cortisol angashintsha ngenxa yezinto ezifana nokucindezeleka okukhulu, ukuzivocavoca umzimba, ukukhulelwa, kanye nemithi ethile.
Umlayezo Wokuya Nawe Ekhaya
- I-Cortisol iyi-hormone elawula ukucindezeleka emizimbeni yethu futhi yenza eminye imisebenzi eminingi ebalulekile.
- Izimpawu ezinjengokukhuluphala ngokuzumayo, ukukhathala, kanye nesiyezi kungabangelwa izinguquko emazingeni e-cortisol.
- Amazinga e-cortisol angalinganiswa ngokuhlolwa kwegazi, amathe, noma umchamo. Amazinga ayo ayahlukahluka kuye ngesikhathi sosuku.
- Uma amazinga e-cortisol ephezulu kakhulu, kungaba uphawu lwe- Cushing's syndrome , futhi uma ephansi kakhulu, kungaba uphawu lwe- Addison's disease .
- Uma unezinye zalezi zimpawu noma ukhathazekile ngemiphumela yokuhlolwa kwakho, qiniseka ukuthi ukhuluma nodokotela wakho . Gwema ukuzihlola wena kanye nokuzelapha.
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