Konke ofuna ukukwazi ngamaphilisi eDarunavir!

Ingabe udokotela wakho ukunike umuthi obizwa ngokuthi i-Darunavir wokwelapha isimo sakho se-HIV? Noma unesithakazelo ngalo muthi? Namuhla sizoxoxa kafushane ngohlobo lomuthi ngempela, ukuthi ungawusebenzisa kanjani, nokuthi yini okudingeka siyiqaphele. Kungenzeka ukuthi uke wabona igama elithi `(Prezista)` njengegama lomkhiqizo walo muthi.

Uhlobo luni lomuthi iDarunavir?

Kalula nje, i-Darunavir iyisidakamizwa sokulwa negciwane lengculaza . Isetshenziselwa ukwelapha ukutheleleka nge-HIV, kodwa hhayi yodwa, kodwa isetshenziswa kanye neminye imithi. Into ebaluleke kakhulu okufanele uyikhumbule ukuthi lo muthi awulona ikhambi lokutheleleka nge-HIV. Kodwa-ke, ungasiza ekulawuleni igciwane le-HIV emzimbeni futhi unciphise ingozi yokusabalalisa i-HIV kwabanye. Kodwa-ke, kubalulekile ukukhumbula ukuthi awukwazi ukuyivimbela ngokuphelele.

Odokotela ngezinye izikhathi bangase bakunike lo muthi kwezinye izimo, ngakho-ke uma uneminye imibuzo mayelana nalokhu, ungabuza udokotela wakho noma usokhemisi.

Yini okufanele ngiyitshele udokotela ngaphambi kokuthatha lo muthi?

Ngaphambi kokuthi uqale ukuthatha i-Darunavir, kubalulekile ukutshela ithimba lakho lokunakekela ngezinto ezimbalwa. Nazi ezinye izinto okufanele uzazi:

• Uma unesifo sikashukela .
• Uma une -hemophilia (isimo lapho igazi lingavimbi kalula).
• Uma unesifo sesibindi .
• Uma uke waba nokusabela okungavamile noma okungezwani ne-Darunavir, imithi ye-sulfa, eminye imithi, ukudla, imibala yokwenziwa, noma izithasiselo.
• Uma ukhulelwe noma uzama ukukhulelwa .
• Uma ungumama oncelisayo .

Ukunikeza udokotela wakho lolu lwazi kusenesikhathi kuzokusiza ukuthi uthole ukwelashwa okuphephile futhi okuphumelelayo.

I-Darunavir kufanele isetshenziswe kanjani?

Lomuthi uza ngesimo sephilisi. Kufanele uphuzwe ngomlomo nengilazi yamanzi. Landela imiyalelo eselebula likadokotela oyinikezwe udokotela wakho ngqo. Kubaluleke kakhulu ukuthatha lo muthi kanye nokudla.

Thatha umuthi wakho ngesikhathi esifanele, njengoba nje udokotela wakho ekutshelile. Ungathathi ngaphezu komthamo onqunyiwe, noma uwuthathe kaningi. Ukuze ukwelashwa kwakho okulwa ne-HIV kusebenze kahle, kubalulekile ukuthatha yonke imithi yakho njengoba nje kunqunyiwe . Ungeqi imithamo. Ngisho noma uzizwa ungcono, ungayeki ukuthatha umuthi wakho ngaphandle kweseluleko sikadokotela wakho. Ukweqa imithamo kungabangela ukuthi igciwane le-HIV limelane nalo muthi neminye imithi.Kungaba "okumelana nokumelana." Lokho kusho ukuthi, lo muthi ungase ungasebenzi ngesikhathi esizayo.

Ingabe lo muthi unganikezwa izingane ezincane?

Yebo, kwezinye izimo ezikhethiwe, lo muthi unganikezwa izingane ezineminyaka engu-3 ubudala. Kodwa-ke, lesi sinqumo senziwa udokotela wezingane. Ngakho-ke, uma unikeza ingane lo muthi, kufanele uxoxe ngakho ngokugcwele nodokotela futhi uqaphele izinyathelo zokuphepha ezifanele.

Yini okufanele uyenze uma uthatha umuthi omningi kakhulu? (Umthamo oweqile)

Uma ucabanga ukuthi usuthathe lo muthi omningi kakhulu, shayela isikhungo sokulawula ubuthi noma igumbi lezimo eziphuthumayo ngokushesha. Lokhu kubaluleke kakhulu.

Khumbula: Lo muthi unikezwe wena kuphela. Ungawunikeli nabanye.

Wenzani uma uphuthelwa umthamo wemithi?

Uma uphuthelwa umthamo, thatha ngokushesha nje lapho ukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo wakho olandelayo, yeqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esihleliwe. Ungalokothi uthathe umthamo ophindwe kabili noma umthamo owengeziwe.

Yimiphi eminye imithi engasebenzisana nalo muthi? (Ukusebenzisana Kwemithi)

Lokhu kubaluleke kakhulu. Eminye imithi ingabangela izinkinga ezinkulu uma ithathwa nge-Darunavir. Ngakho-ke, uma uthatha eminye imithi, amakhambi, noma amavithamini, kufanele utshele udokotela wakho ngayo.

Ungalokothi usebenzise i-Darunavir nale mithi:

Kuyelulekwa kakhulu ukuthi ungasebenzisi i-Darunavir kanye nale mithi, ngoba lokhu kungabangela imiphumela emibi kakhulu:

• `alfuzosin`
• Eminye imithi yokwelapha umfutho wegazi, isifo senhliziyo, kanye nokuphazamiseka kwesigqi senhliziyo: isibonelo, `dronedarone`, `ivabradine`, `ranolazine`
• `cisapride`
• `colchicine` (uma unezinkinga zesibindi noma zezinso)
• `elbasvir`; `grazoprevir`
• `lurasidone`
• Imithi yokwehlisa i-cholesterol: isibonelo `lomitapide`, `lovastatin`, `simvastatin`
• Imithi yokwelapha ikhanda: Isibonelo, i-dihydroergotamine, i-ergonovine, i-ergotamine, i-methylergonovine
• `i-midazolam` (ithathwa ngomlomo)
• `naloxegol`
• `pimozide`
• Ilayisi lemvubelo ebomvu (abanye abantu bathatha lokhu njengesengezo)
• `rifampin`
• I-Sildenafil (uma inikezwa njengokwelashwa komfutho wegazi ophezulu we-pulmonary arterial)
• I-St. John's Wort (lena isitshalo)
• `i-triazolam`

Le mithi ingasebenzisana neDarunavir:

Futhi, kuneminye imithi engasebenzisana neDarunavir ngandlela thile. Ngakho-ke, uma uthatha le mithi, kufanele utshele nodokotela wakho:

• `artemether`; `lumefantrine`
• `bosentan`
• Amanye ama-antibiotic: isibonelo, i-clarithromycin, i-rifabutin, i-rifapentine
• Eminye imithi yokulwa namagciwane ye-HIV: isibonelo `didanosine`, `indinavir`, `maraviroc`, `saquinavir`, noma `lopinavir`; `ritonavir`
• Eminye imithi yokukhathazeka noma yokungalali: isibonelo `buspirone`, `diazepam`, `estazolam`, `zolpidem`
• Eminye imithi yokwelapha umfutho wegazi nesifo senhliziyo: isibonelo `amlodipine`, `carvedilol`, `diltiazem`, `felodipine`, `metoprolol`, `nicardipine`, `nifedipine`, `timolol`, `verapamil`
• Eminye imithi yomdlavuza: isibonelo `dasatinib`, `nilotinib`, `vinblastine`, `vincristine`
• Eminye imithi yokucindezeleka: isibonelo, i-amitriptyline, i-desipramine, i-imipramine, i-nortriptyline, i-paroxetine, i-sertraline, kanye ne-trazodone
• Eminye imithi yokwelapha ukungasebenzi kahle kwenduku: isibonelo, i-avanafil, i-sildenafil, i-tadalafil, i-vardenafil
• Eminye imithi yokwelapha izifo zesikhunta: isibonelo, i-itraconazole, i-ketoconazole, i-posaconazole, i-voriconazole
• Eminye imithi yokwelapha i-hepatitis: isibonelo, i-boceprevir, i-simeprevir
• Eminye imithi yokwelapha ukuphazamiseka kwengqondo: isibonelo, i-quetiapine, i-risperidone, i-thioridazine
• Eminye imithi yokwelapha ukuxhuzula: isibonelo, i-carbamazepine, i-phenobarbital, i-phenytoin
• Eminye imithi evimbela noma elapha amahlule egazi: isibonelo `apixaban`, `rivaroxaban`, `warfarin`
• `i-clopidogrel`
• Ama-hormone abesifazane: Isibonelo, amaphilisi okuvimbela inzalo aqukethe ama-estrogen nama-progestin
• Imithi yokwehlisa i-cholesterol: isibonelo, i-atorvastatin, i-pravastatin, i-rosuvastatin
• Imithi yokushaya kwenhliziyo okungajwayelekile: isibonelo `amiodarone`, `bepridil`, `digoxin`, `disopyramide`, `flecainide`, `lidocaine`, `mexiletine`, `propafenone`, `quinidine`
• Imithi yokucindezela amasosha omzimba (njengemuva kokufakelwa): isibonelo `cyclosporine`, `everolimus`, `sirolimus`, `tacrolimus`
• Izibulali-zinhlungu: Isibonelo, `buprenorphine`, `buprenorphine`; `naloxone`, `methadone`
• `i-omeprazole`
• `i-salmeterol`
• Ama-steroid: Isibonelo, i-betamethasone, i-budesonide, i-ciclesonide, i-dexamethasone, i-fluticasone, i-methylprednisolone, i-mometasone, i-prednisolone, i-triamcinolone
• `ticagrelor`

Lolu hlu lungase lungahlanganisi yonke imiphumela emibi engaba khona. Ngakho-ke, kubalulekile ukutshela udokotela wakho ngayo yonke imithi, imikhiqizo yamakhambi, imithi engekho ngaphansi kukadokotela, kanye nezithasiselo zokudla ozithathayo.Tshela udokotela wakho ngempilo yakho. Futhi, tshela udokotela wakho uma ubhema, uphuza utshwala, noma usebenzisa izidakamizwa ezingekho emthethweni. Ezinye zalezi zinto zingathintana nemithi yakho.

Yiziphi izinto okufanele uziqaphele uma usebenzisa lo muthi?

Kubalulekile ukunaka impilo yakho njalo ngenkathi usebenzisa i-Darunavir.

• Ukuhlolwa okuvamile: Qhubeka ubona udokotela wakho noma umhlinzeki wezempilo ukuze ahlolwe. Uma uthola izimpawu ezintsha, khuluma nodokotela wakho ngazo. Kungase kudingeke futhi ukuthi kwenziwe umsebenzi wegazi obalulekile ngenkathi uthatha lo muthi.
• Ukusabela okukhulu kwesikhumba: Ukusabela okukhulu kwesikhumba kungase kwenzeke zingakapheli amasonto noma izinyanga ezimbalwa uqale lo muthi. Uma uhlaselwa umkhuhlane kanye nezimpawu ezifana nomkhuhlane, tshela udokotela wakho ngokushesha. Lokhu kuqubuka kungase kube bomvu noma kube nsomi, bese kuba amabhamuza kanye nokuqhekeka kwesikhumba. Noma ungase ube nokuvuvukala okubomvu okunokuvuvukala kobuso, izindebe, noma ama-lymph node avuvukele entanyeni noma emakhwapheni. Uma ubona into efana nale, ungalibali .
• Ukusabalala kwe-HIV: I-HIV isakazeka ngokuxhumana ngokocansi noma ngokuxhumana ngegazi. Khuluma nodokotela wakho mayelana nendlela yokuvimbela ukusabalala kwe-HIV. Qaphela imikhuba yocansi ephephile kanye nezinye izinyathelo zokuphepha.
• Amaphilisi okulawula ukubeletha: Amaphilisi okulawula ukubeletha angase angasebenzi kahle ngenkathi uthatha lo muthi. Ngakho-ke, khuluma nodokotela wakho ngendlela eyengeziwe yokulawula ukubeletha. Abesifazane abaneminyaka yokuzala kufanele basebenzise indlela yokuvimbela ukubeletha ethembekile, njengekhondomu noma i-diaphragm.
• Ushukela egazini: Lo muthi ungase wandise ushukela egazini lakho. Uma unesifo sikashukela, buza udokotela wakho uma udinga ukwenza noma yiziphi izinguquko ekudleni kwakho noma emithini.

Yimiphi imiphumela emibi engaba khona yalo muthi?

Njenganoma yimuphi umuthi, i-Darunavir ingabangela imiphumela emibi. Eminye iyingozi futhi idinga ukunakekelwa kwezokwelapha ngokushesha, kanti eminye ivame ukungabi yimbi kakhulu.

Imiphumela emibi okufanele ibikwe kudokotela wakho noma kuchwepheshe wezempilo ngokushesha okukhulu:

• Ukusabela kokungezwani komzimba : ukuqubuka kwesikhumba, ukulunywa noma ukuqubuka, ukuvuvukala kobuso, izindebe noma ulimi.
• Ukwanda kwendlala noma ukoma.
• Ubuhlungu bemisipha noma amalunga.
• Ukuqubuka kwesikhumba, umkhuhlane, kanye nokuvuvukala kwama-lymph node.
• Ukubomvu noma ukuvuvukala kwamehlo.
• Ubomvu, ukuqubuka, ukuxebuka, noma isikhumba esixegayo (kungavela nangaphakathi emlonyeni).
• Izimpawu zokutheleleka : umkhuhlane noma ukubanda; ukukhwehlela; umphimbo obuhlungu; ubuhlungu noma ubunzima bokuchama.
• Izimpawu zokulimala kwesibindi : Umchamo ophuzi omnyama noma onsundu; ukuzizwa ungaphilile kahle noma ushisa; indle ekhanyayo; ukuphelelwa yisifiso sokudla; ​​isicanucanu noma ukuhlanza; ubuhlungu esiswini esingaphezulu kwesokudla; ​​ukuzizwa ubuthakathaka noma ukhathele ngendlela engajwayelekile; ukuphuzi kwamehlo noma isikhumba.
• Izimpawu zoshukela ophezulu egazini : Ukuzizwa womile noma ulambile kakhulu kunokujwayelekile, noma udinga ukuchama kaningi. Ungase uzizwe ukhathele kakhulu futhi ungaboni kahle.

Imiphumela emibi evame ukungadingi ukunakekelwa kwezokwelapha (tshela udokotela wakho uma lokhu kuqhubeka noma kukhathaza):

• Uhudo
• Ikhanda elibuhlungu
• Ubuhlungu besisu
• Isisu esibuhlungu
• Ukwanda kwesisindo okhalweni nasemhlane, noma ukuncipha kobuso, izingalo, nemilenze (izinguquko endleleni amafutha omzimba asakazwa ngayo).

Lolu hlu lungase lungahlanganisi yonke imiphumela emibi. Uma uhlangabezana nanoma yiziphi izimpawu ezingavamile, xhumana nodokotela wakho. Ungabika futhi imiphumela emibi ku-FDA ku-1-800-FDA-1088.

Ngingawugcina kanjani umuthi wami? (Isitoreji)

• Gcina lo muthi kude nezingane . Ubaluleke kakhulu.
• Gcina ekamelweni lokushisa (phakathi kwama-degree Celsius angu-15 no-30, phakathi kwama-degree Fahrenheit angu-59 no-86).
• Ungasebenzisi noma ulahle noma yimuphi umuthi ophelelwe yisikhathi.

Khumbula, lesi sihloko siyisifinyezo nje. Singase singabi nalo lonke ulwazi. Uma uneminye imibuzo mayelana nalo muthi, khuluma nodokotela wakho, usokhemisi, noma omunye umhlinzeki wezempilo.

Okokugcina, izinto okufanele uzikhumbule (Umyalezo Wokuya Ekhaya)

I-Darunavir umuthi odlala indima ebalulekile ekwelapheni ukutheleleka nge-HIV.

• Sebenzisa kahle: Thatha lo muthi njengoba nje udokotela wakho ekutshela, ngesikhathi esifanele, kanye nokudla. Ungayeki ukudla noma uyeke ukuwuthatha ngokuzumayo.
• Yaziswa: Tshela udokotela wakho ngayo yonke eminye imithi oyithathayo, noma yiziphi ezinye izifo onazo, kanye nokuthi ukhulelwe.
• Qaphela: Qaphela izimpawu ezintsha, ikakhulukazi ukusabela kwesikhumba. Uma unenkinga, bona udokotela wakho ngokushesha.
• Hlala uphephile: Landela izindlela eziphephile zokuvimbela ukusabalala kwe-HIV. Cabanga futhi ngokulawula inzalo.

Impilo yakho ibaluleke kakhulu kuwe. Kwangathi ungathola amandla okuphila impilo enempilo ngokusebenzisa lo muthi ngendlela efanele nangokulandela imiyalelo kadokotela!

I- Darunavir, i-HIV, i-antiretroviral, i-Prezista, imithi, imiphumela emibi, ukwelashwa nge-HIV