Ingabe udokotela wakho ukutshelile ukuthi unesifo sikashukela, noma ukuthi ususondele ekutholeni isifo sikashukela (prediabetes)? Uma usho lokho, kungenzeka ukuthi uke wezwa igama elithi "ukumelana ne-insulin". Ungase uzibuze ukuthi liyini leli gama elisha. Ungesabi. Namuhla sizoxoxa ngalokhu kanye nemithi enikezwayo yalesi simo. Masiqonde lezi zinto kalula, njengokukhuluma nomngane.
Kuyini Ukuzwela Kwe-Insulin?
Kalula nje, i-insulin iyi-hormone ebaluleke kakhulu ekhiqizwa yisitho emzimbeni wethu esibizwa ngokuthi i-pancreas. Uma ushukela (i-glucose) ekudleni esikudlayo ungena egazini, kuyisihluthulelo esisiza ushukela ungene emangqamuzaneni omzimba futhi udale amandla.
Cabanga ukuthi amangqamuzana emzimbeni wakho ayiminyango, futhi i-insulin iyisihluthulelo esivula leyo minyango.
- Ukuba nokuzwela okuhle kwe-insulin kusho ukuthi: Uma ufaka lesi sihluthulelo (i-insulin), umnyango (iseli) uvuleka kalula. Ushukela osegazini ungena kalula emaseli futhi uguqulwa ube amandla.
- Ukumelana ne-insulin kusho ukuthi: Leso sihluthulelo sinenkinga yokuvula umnyango. Kufana nokuthi umnyango ubambekile. Ngakho-ke ngenxa yokuthi umnyango awukwazi ukuvulwa, amazinga kashukela egazini ayakhuphuka. Ngemuva kwalokho i-pancreas iqala ukwenza i-insulin eningi, njengokuletha okhiye abaningi ukuvula umnyango obambekile. Ngokuhamba kwesikhathi, yilokhu okubangela isifo sikashukela (uhlobo lwesibili lwesifo sikashukela).
Ngakho-ke, lokho okwenziwa yimithi yokuzwela i-insulin ukwenza leyo minyango ebambekile ibe lula ukuyivula. Okusho ukuthi, isiza i-insulin ukuthi isebenze kahle.
Yimiphi imithi eyinhloko yalokhu?
Indlela engcono kakhulu yokuthuthukisa ukuzwela kwe-insulin iwukushintsha indlela yokuphila. Lokhu kuhlanganisa ukuzivocavoca njalo, ukudla ukudla okunomsoco, nokulawula isisindo sakho. Kodwa-ke, udokotela wakho angase akunike imithi kanye nalokhu.
Kunezinhlobo ezimbili eziyinhloko zemithi.
1. Ama-Biguanides - Umuthi okuwukuphela kwawo kulesi sigaba yi-Metformin eyaziwayo.
2. I-Thiazolidinediones (TZDs) - Kukhona nemithi kuleli qembu.
Ake sibheke ngayinye yalezi zinhlobo ngokwehlukana.
I-Metformin, esiyaziyo sonke
I-Metformin iwumuthi osetshenziswa kakhulu wesifo sikashukela sohlobo lwesibili emhlabeni. Uma unesifo sikashukela, kungenzeka ukuthi uthatha lo muthi.
I-metformin isebenza kanjani?
I-Metformin isiza ukulawula ushukela egazini ngezindlela ezimbili eziyinhloko:
- Kunciphisa ukukhiqizwa kukashukela yisibindi: Isibindi sethu siphinde sikhiqize ushukela uma umzimba uwudinga. Njengoba i-metformin ilawula le nqubo, inani likashukela elingadingekile eliqongelela egazini liyancishiswa.
- Kwandisa ukuzwela kwe-insulini emisipheni: Lokhu kuyinto ebaluleke kakhulu. Amaseli emisipha aqala ukusabela kahle ku-insulini. Bese ushukela osegazini ungena kalula emisipheni bese uguqulwa ube amandla.
Ucwaningo lukhombisile ukuthi ukuthatha i-metformin kungasiza ekubambezeleni ukuqala kwesifo sikashukela kubantu abasengozini futhi kuvikele ezimweni ezifana nesifo senhliziyo.
| Kafushane nge-Metformin | |
|---|---|
| Isilinganiso | Udokotela wakho uzonquma umthamo. Ngokuvamile bazoqala ngomthamo ophansi bese bewukhulisa kancane kancane. Ungase utshelwe ukuthi uwuthathe kanye noma kabili ngosuku ngesikhathi sokudla. |
| Imiphumela Emibi Evamile | Ukuphazamiseka kwesisu, isicanucanu, ukuhlanza, futhi ikakhulukazi uhudo kungase kwenzeke. Lokhu kuvame ukuphela ezinsukwini ezimbalwa njengoba umzimba ujwayela imithi. Lokhu kungancishiswa kakhulu ngokuthatha imithi kanye nokudla. |
| Izinto okufanele uziqaphele | Lo muthi awufaneleki uma unesifo sezinso esibi kakhulu . Futhi, kungase kube nesimo esingavamile kodwa esiyingozi esibizwa ngokuthi "i-lactic acidosis". Uma uzwa izimpawu ezifana nokuqaqamba kwemisipha, ukukhathala okukhulu, isicanucanu, nokuphefumula ngokushesha, hamba uye emnyangweni wezimo eziphuthumayo esibhedlela (ETU) ngokushesha. |
Ngokungafani neminye imithi yesifo sikashukela, i-metformin ayivamisile ukubangela ukukhuluphala. Abanye abantu bangase banciphise nesisindo.
Ama-Thiazolidinediones (ama-TZD)
Leli elinye iqembu lemithi. Lokhu kwandisa nokuzwela kwe-insulin. Kunezinhlobo ezimbili eziyinhloko zemithi kuleli qembu: i-Pioglitazone kanye ne-Rosiglitazone .
Odokotela bavame ukuncoma i-metformin kuqala. Uma kunzima ukuyilawula noma ngezinye izizathu, ungase ucabangele lolu hlobo lwemithi ye-TZD.
Kubaluleke kakhulu: Uma uke waba nokwehluleka kwenhliziyo okubangelwa ukuminyana noma uke waba nokukhubazeka kwenhliziyo, le mithi ye-TZD ayifaneleki nhlobo , njengoba ingenza isimo sibe sibi kakhulu.
| Uhlobo lomuthi | Izinto okufanele uzazi |
|---|---|
| I-Pioglitazone | Lokhu kwandisa nokuzwela kwe-insulin. Ezinye izifundo ziphakamise ukuthi kungaba nemiphumela esibindini, kwandise ingozi yomdlavuza wesinye, futhi kwandise ingozi yokuphuka kwamathambo. |
| I-Rosiglitazone | Lokhu kusebenza ngendlela efanayo nomuthi ongenhla. Nakuba kuye kwaphakanyiswa ukukhathazeka esikhathini esidlule mayelana nengozi yesifo senhliziyo, izifundo zakamuva azikuqinisekisanga lokhu. Kodwa-ke, kubalulekile ukuqaphela isifo senhliziyo uma usebenzisa zombili lezi zidakamizwa. |
| Imiphumela emibi evamile ye-TZDs | Izimpawu zingase zihlanganise ukukhuluphala, ukuvuvukala ngenxa yokugcinwa koketshezi emzimbeni, ubuhlungu besifuba, kanye nobunzima bokuphefumula. Uma uhlangabezana nanoma yiziphi zalezi zimpawu, xhumana nodokotela wakho ngokushesha. |
Uyikhetha kanjani imithi efanele wena?
Lona umbuzo obaluleke kakhulu. Kodwa akusikho okwakho ukuphendula, kungokwadokotela wakho . Ngoba ucabangela izinto eziningi lapho ekhetha umuthi ofanele wena.
- Injani isifo sakho sikashukela?
- Ingabe unazo ezinye izinkinga zempilo (isifo senhliziyo, isifo sezinso, isifo sesibindi)?
- Uneminyaka emingaki futhi uphila impilo enjani?
- Yimiphi imiphumela emibi kanye nezinzuzo kanye nokungalungi komuthi?
Kungemva kokucabangela konke lokhu lapho enquma khona umuthi ofanele futhi ophephile kakhulu kanye nomthamo wawo kuwe.Ungalokothi usebenzise umuthi ophuzwa umngane, noma umuthi onconywa ngomunye umuntu, ukuze uziphindiselele.
Umlayezo Wokuya Nawe Ekhaya
- Ukumelana ne-insulin kwenzeka lapho amangqamuzana omzimba wakho engasabeli kahle ku-insulin. Lesi yisona sizathu esiyinhloko sesifo sikashukela sohlobo 2.
- Imithi ye-Metformin kanye ne-TZD yimithi eyinhloko esiza ukwandisa ukuzwela kwe-insulin.
- Okubaluleke njengemithi, futhi mhlawumbe ngisho nangaphezulu, ukudla okufanele kanye nokuzivocavoca njalo kubalulekile ekwandiseni ukuzwela kwe-insulin.
- Udokotela wakho kuphela ongakunikeza umuthi. Thatha umthamo awunikezayo, njengoba nje uyalelwe, nangesikhathi esifanele.
- Ngaphambi kokuqala noma yimuphi umuthi omusha, khuluma nodokotela wakho ngokukhululekile ngezinzuzo zawo, izingozi, kanye nemiphumela emibi engaba khona. Ungesabi noma ube namahloni. Kuyilungelo lakho.
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