Ingabe udokotela ukutshelile ukuthi kunenkinga ngesigqi senhliziyo yakho, okungukuthi, ijubane lokushaya kwenhliziyo yakho? Kumelwe ukuthi uzizwe wesaba kancane, akunjalo? I-Dofetilide uhlobo lomuthi olunikezwa ngezikhathi ezinjalo. Ngakho-ke, namuhla sizokhuluma ngalomuthi obizwa ngokuthi i-Dofetilide, njengokungathi sitshela umngane.
Iyini i-Dofetilide?
Kalula nje, i-Dofetilide umuthi oqeda ukushaya kwenhliziyo . Lokhu kusho ukuthi uyasiza ekwenzeni inhliziyo yakho ishaye kahle. Ivame ukuza ngesimo se-capsule. Ivame ukuthathwa kanye noma kabili ngosuku. Kungenzeka ukuthi uyibonile ngaphansi kwegama lomkhiqizo i-Tikosyn®.
Kodwa kukhona into eyodwa okufanele uyikhumbule. Umthamo walo muthi, okungukuthi, inani onikwa lona ukuthi uphuze, ungahluka kumuntu nomuntu . Uma umngane wakho ethatha lo muthi, ngeke unikezwe inani elifanayo nelalowo anikwa lona. Udokotela uzohlola isimo sakho futhi akunike umthamo ofanele (njenge-`125 mcg, 250 mcg` noma `500 mcg`). `(mcg)` imele ama-microgram.
Kumaphi amacala lapho kusetshenziswa khona i-Dofetilide?
Lo muthi usetshenziswa kakhulu ukwelapha izinkinga ezithile zesigqi senhliziyo nokuvimbela ukuthi zingaphinde zivele.
Ukuphazamiseka kwesigqi senhliziyo
- I-Atrial Fibrillation (Afib): Lokhu kwenzeka lapho amakamelo aphezulu enhliziyo yakho (abizwa nangokuthi i-atria) eshaya ngokushesha nangokungajwayelekile, kunokuba kube ngendlela enesigqi. Cabanga ngakho njengesigubhu okufanele sidlalwe ngendlela ethile, kodwa sishaya ngendlela engafanele bese siyahlanya. Lokhu kubizwa ngokuthi "Afib".
- Ukushaqeka kwe-Atrial: Lena enye indlela yokushaya kwenhliziyo engavamile eyenzeka emakamelweni aphezulu enhliziyo. Ifana kancane ne-"Afib", kodwa kukhona umehluko omncane.
Okubalulekile: Kuzo zombili lezi zimo, ukusebenza kwenhliziyo kuba okungajwayelekile, ngakho igazi lingase lingampompi kahle. Lokhu kungaholela ezinkingeni ezahlukahlukene. Ngakho-ke, lo muthi usebenza ngokulungisa lokho kungahambi kahle nokwenza inhliziyo isebenze kahle futhi.
Ukusetshenziswa "okungafakwanga ilebula"
Ngezinye izikhathi odokotela banikeza i-Dofetilide kwezinye izimo zenhliziyo ngaphandle kokusetshenziswa kwayo kwasekuqaleni. Lokhu kubizwa ngokuthi ukusetshenziswa "okungekho kulabel". Okusho ukuthi, odokotela bayazi ukuthi umuthi ungasiza ngalezo zimo, kodwa wawungavunyelwe ekuqaleni kulezo zimo.
Ezinye izinkinga ezifanayo zesigqi senhliziyo yilezi:
- I-Ventricular Tachycardia: Kulokhu, amakamelo aphansi enhliziyo ashaya ngokushesha okukhulu.
- I-Supraventricular Tachycardias: Lokhu futhi ukushaya kwenhliziyo okusheshayo okwenzeka emakamelweni aphezulu enhliziyo. Kunezinye izinhlobo ngaphandle kwe-`(Afib)` kanye ne-`(Atrial Flutter).`
- I-Wolff-Parkinson-White Syndrome: Lesi yisimo lapho inhliziyo ishaya khona ngokushesha ngenxa yomgudu kagesi owengeziwe enhliziyweni.
Ungaqala kanjani i-Dofetilide?
Lokhu kukhethekile kancane. Uma uqala ukuthatha i-Dofetilide, kuzodingeka uhlale esibhedlela cishe izinsuku ezintathu kuya kwezine . Lokhu kungase kuzwakale kungavamile, akunjalo? Isizathu ukuthi odokotela bafuna ukubheka ukuthi umuthi uthinta kanjani isigqi senhliziyo yakho nokuthi ngabe uhlangabezana nezinkinga ezintsha yini. Bazosebenzisa lesi sikhathi ukuthola umthamo ofanele wena. Ngesikhathi usesibhedlela, bangashintsha inani lomuthi owunikezwayo. Ungakhathazeki, konke lokhu kungenxa yokuphepha kwakho.
Ungayithatha kanjani i-Dofetilide ekhaya?
Ngemva kokufika ekhaya uvela esibhedlela, ilebula likadokotela onikwa lona lizochaza ngokucacile ukuthi kufanele ulithathe kangaki nokuthi kufanele ulithathe kangaki ngosuku.
Kubaluleke kakhulu ukukhumbula la maphuzu:
- Thatha umuthi njengoba nje udokotela ekutshelile. Ungawukhuphuli noma uwunciphise umthamo.
- Thatha umuthi ngesikhathi esifanayo nsuku zonke. Uma kusekuseni, thatha ekuseni, uma kukusihlwa, thatha ebusuku. Ungashintshi isikhathi.
- Ngisho noma uzizwa ungcono, ungayeki ukuthatha umuthi. Qhubeka uwuthatha uma nje udokotela wakho ekutshelile.
- Ungawuthatha lo muthi noma ungenawo ukudla.
- Ungayeki imithi yakho.
- Thatha kuphela inani elinqunywe udokotela.
Uma unemibuzo mayelana nemithi yakho noma ukuthi ungayigcwalisa kanjani, ungesabi ukubuza udokotela wakho noma usokhemisi. Uma kukhona ongakuqondi, bacele bakuchazele.
Yini okufanele ngiyitshele udokotela wami ngaphambi kokuthatha i-Dofetilide?
Ngaphambi kokukunikeza lo muthi, kubalulekile ukutshela udokotela wakho okulandelayo:
- Wake waba nokusabela kokungezwani komzimba ne-dofetilide? Uma kunjalo, sicela uchaze okwenzekile.
- Bhala yonke imithi oyithathayo njengamanje (imithi kadokotela, imithi ethengiswa ngaphandle kwemithi kadokotela (OTC), amavithamini, kanye nezithasiselo zamakhambi). Ungaqali noma yimiphi imithi emisha noma izithako ngaphandle kokubonisana nodokotela wakho kuqala.
- Sitshele uma unesifo senhliziyo, ikakhulukazi isifo senhliziyo esibizwa ngokuthi 'i-Long QT Syndrome' , noma uma unesifo sezinso noma sesibindi, noma uma unamazinga aphansi e-potassium noma i-magnesium egazini lakho.
- Qiniseka ukuthi uyasitshela uma ukhulelwe, uzama ukukhulelwa, noma uncelisa .
Yimiphi imithi okungafanele ithathwe ne-Dofetilide?
Uma uthatha le mithi, ukuthatha i-Dofetilide kungaba yingozi kakhulu.Ngakho-ke, uma usebenzisa umuthi onjengalona, kufanele utshele udokotela wakho nakanjani. Khona-ke ngeke akunike i-Dofetilide.
- I-Cimetidine (isib. i-Tagamet®)
- I-Cisapride
- I-Dolutegravir (isb., i-Tivicay®)
- I-Verapamil (`Verapamil` - isb. `Calan®`)
- I-Ketoconazole
- I-Itraconazole (isib. i-Sporanox®)
- I-Trimethoprim (`Trimethoprim` - isibonelo `Proloprim®`)
- I-Trimethoprim ene-sulfamethoxazole (isib., i-Bactrim®, i-Septra®)
- I-Hydrochlorothiazide (`Hydrochlorothiazide` - isibonelo `Microzide®`)
- I-Ziprasidone
- Ama-antidepressant e-Tricyclic afana ne-amitriptyline
- I-Promethazine
- I-Prochlorperazine (isib., i-Compro®)
- I-Quinidine
- I-Disopyramide (isib., i-Norpace®)
- I-Sotalol (`Sotalol` - isb. `Betapace®`)
Eminye imithi engasebenzisana ne-Dofetilide
Kuneminye imithi engasebenzisana ne-Dofetilide. Lokhu kusho ukuthi uma uthatha le mithi ndawonye, ingashintsha indlela i-Dofetilide esebenza ngayo noma yandise imiphumela yayo emibi. Ngakho-ke, uma uthatha noma yimiphi yemithi ebhalwe ngezansi, khuluma nodokotela wakho ngaphambi kokuqala i-Dofetilide.
- I-Amiodarone (`Amiodarone` - isb. `Cordarone®`)
- I-Digoxin (`Digoxin` - isibonelo `Lanoxin®`)
- I-Metformin (`Metformin` - isibonelo `Glucophage®`)
- I-Megestrol
- I-Diltiazem (isib. i-Cardizem®)
- I-Zafirlukast
- I-Quinine
- I-Fluconazole
- I-Erythromycin (`Erythromycin` - isibonelo `PCE®`)
- I-Clarithromycin
- Ama-antibiotic e-Fluoroquinolone afana ne-Norfloxacin ne-Moxifloxacin
- Ama-SSRI (ama-Selective Serotonin Reuptake Inhibitors) njenge-Fluoxetine, i-Sertraline, i-Paroxetine (isib. i-Paxil®)
- Imithi yokukhipha amanzi emzimbeni efana ne-Furosemide, i-Triamterene, ne-Amiloride
- Ama-protease inhibitors (imithi yezifo ezifana ne-HIV) njenge-Indinavir
Ukuqaphela nje: Njengeminye imithi, ukuphuza ijusi likagrapefruit (isithelo esifana negrapefruit) kungandisa izinga lomuthi i-dofetilide emzimbeni wakho. Lokhu kungaba yingozi. Ngakho-ke, buza udokotela wakho ukuthi kulungile yini ukuphuza ijusi likagrapefruit ngenkathi uthatha lo muthi.
Yini okufanele uyenze uma uphuthelwa umthamo wemithi?
Uma lokhu kwenzeka, thatha umthamo ophuthelwe ngokushesha nje lapho ukhumbula . Kodwa-ke, uma sekuyisikhathi somthamo wakho olandelayo lapho ukhumbula, yeqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esihleliwe. Ungalokothi uthathe umthamo ophindwe kabili. Uma ungaqiniseki ukuthi wenzeni, khuluma nodokotela wakho noma nosokhemisi.
Yiziphi izinzuzo ze-Dofetilide?
I-Dofetilide ingasiza ekulawuleni ukushaya kwenhliziyo okungajwayelekile enhliziyweni yakho, okungenza impilo yakho ibe lula kancane. Kodwa-ke, kubalulekile ukukhumbula ukuthi ayilaphi ngokuphelele lesi sifo.
Yiziphi imiphumela emibi ye-Dofetilide?
Njenganoma yimuphi umuthi, i-Dofetilide ingabangela imiphumela emibi. Akuwona wonke umuntu oyitholayo, kodwa kuhle ukuqaphela.
Imiphumela emibi emincane engaba khona:
- Ubuhlungu besifuba
- Ikhanda elibuhlungu (ikhanda elibuhlungu)
- Isiyezi (i-vertigo)
- Isicanucanu (ukuzizwa sengathi uhlanza)
- Uhudo (ubuhlungu besisu)
- Ubuhlungu besisu
Into okufanele uyiqaphele kakhulu:
I-Dofetilide inikezwa ukulungisa ukushaya kwenhliziyo okungajwayelekile, kodwa kukhona ingozi yolunye uhlobo lokushaya kwenhliziyo okungajwayelekile ngalo muthi. Ikakhulukazi, ukushaya kwenhliziyo okusheshayo emakamelweni aphansi enhliziyo (`ventricular tachycardia`) okubizwa ngokuthi ``Torsades de Pointes`` kungenzeka.
Lesi yisona sizathu esiyinhloko sokuthi kungani udinga ukulaliswa esibhedlela futhi uqale ukusebenzisa imithi! Odokotela bafuna ukukuqapha eduze ukuze babone lokhu kushaya kwenhliziyo okuyingozi nokungavamile.
Ngizozizwa ngingcono ngokushesha kangakanani ngemva kokuqala umuthi?
I-Dofetilide ithatha cishe amahora amabili kuya kwamathathu ukuqala ukusebenza. Kodwa-ke, noma ngabe uzizwa ungcono, ungayeki ukuthatha umuthi kuze kube yilapho udokotela wakho ekuyala ukuthi uwuthathe. Qhubeka uwuthatha.
Ngingayinakekela kanjani impilo yami ngenkathi ngithatha i-Dofetilide?
Kunezinto ezimbalwa okudingeka uzenze ngesikhathi uthatha lo muthi.
- Qiniseka ukuthi uya kuzo zonke izikhathi zakho zokuqokwa nodokotela wakho, okuhlanganisa nokuhlolwa kwelebhu. Yilapho-ke ongabona khona ukuthi umuthi ukuthinta kanjani.
- Cishe kuzodingeka ukuthi uhlolwe nge-electrocardiogram (EKG) cishe kanye njalo ezinyangeni eziyisithupha . Lokhu kuzohlola izinga kanye nesigqi sokushaya kwenhliziyo yakho.
- Bangase futhi bacele ukuhlolwa kwegazi ukuze babone ukuthi umthamo wemithi udinga ukushintshwa yini.
- Funda njalo incwajana yolwazi ehambisana nomuthi wakho, ikakhulukazi uma kube noshintsho lwakamuva emithini yakho noma esimweni sakho sempilo. Buza usokhemisi wakho uma unemibuzo.
Ezinye izinto ongazenza:
- Uma uhlinzwa, uhlinzwa ngamazinyo, noma uphathwa ngendlela ephuthumayo, tshela udokotela noma udokotela wamazinyo ukuthi uphuza i-Dofetilide.
- Kungase kudingeke futhi ukuthi ugqoke ikhadi lokuzazisa elichaza ukuthi uthatha i-Dofetilide.
- Ungalokothi uyeke ukuthatha lo muthi ngaphandle kokubuza udokotela wakho.
- Landela iseluleko sikadokotela wakho mayelana nokudla neziphuzo, ikakhulukazi iziphuzo ezidakayo.
- Hlala ugcina imithi eyanele nawe. Ngaphambi kokuya eholidini noma ohambweni, hlola ukuthi imithi yakho iyancipha yini. Ngaphandle kwalokho, ungase ungakwazi ukuyithola esimweni esiphuthumayo.
Kufanele ubonane nini nodokotela?
Uma uhlangabezana nanoma yiziphi zalezi zimpawu, shayela udokotela wakho ngokushesha noma uye ekamelweni eliphuthumayo:
- Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile.
- Ukuzwa sengathi inhliziyo yakho ishaya ngokushesha, ukuzwa sengathi ukushaya kwenhliziyo yakho kuyashesha.
- Ubuhlungu besifuba.
- Ukuzizwa unesiyezi noma uzizwa unekhanda elikhanyayo (`unekhanda elikhanyayo`).
- Ubunzima bokuphefumula.
- Uhudo olubi kakhulu.
- Ukuhlanza okubangela ukulahlekelwa yisifiso sokudla.
- Ukujuluka okungavamile.
- Ukomela amanzi okwandayo.
- Ukuqhuma kwesikhumba.
Ngisho noma kunemiphumela emibi engatheni njengale, khuluma nodokotela wakho uma ikukhathaza:
- Ikhanda elibuhlungu.
- Ukungalali.
- Noma yimiphi eminye imiphumela emibi ekukhathazayo.
Ngingayithenga kuphi i-Dofetilide?
I-Dofetilide ayitholakali kuwo wonke amakhemisi. Ngakho-ke, shayela ikhemisi eliseduze nawe ukuze ubone ukuthi banayo yini. Uma unenkinga yokuthola umuthi, khuluma nodokotela wakho.
Ungagcina kanjani i-Dofetilide?
- Gcina i-Dofetilide esitsheni esivalwe kahle, endaweni eyomile, ekushiseni kwegumbi .
- Ungayibeki elangeni eliqondile noma ezindaweni ezishisayo.
- Ungagcini lo muthi ezindaweni ezinomswakama ophezulu, njengasendlini yokugezela. Umswakama ungabhubhisa izakhiwo zomuthi.
- Gcina lo muthi ungagcini nje ngokugcina, kodwa yonke eminye imithi ungafinyeleleki ezinganeni.
- Ungalokothi wabelane ngemithi yakho nanoma ubani omunye.
- Ungalokothi usebenzise imithi ephelelwe yisikhathi. Amanye amaphakheji emithi anosuku lokuphelelwa yisikhathi olubhalwe kuwo. Noma, uma ungaqiniseki ukuthi imithi indala kangakanani, shayela ikhemisi lakho ubuze.
Okokugcina, izinto okufanele uzikhumbule
Kungaba yinto ekhathazayo kakhulu ukwazi ukuthi unenkinga yesigqi senhliziyo. Kodwa-ke, uma udokotela wakho ekunike i-Dofetilide, ingakusiza. Into ebaluleke kakhulu ukulandela imiyalelo kadokotela kanye nemiyalelo esephaketheni lemithi ngqo. Uma uneminye imibuzo noma ukukhathazeka ngalo muthi, ungangabazi ukubuza udokotela wakho noma usokhemisi. Bazokwazi ukukusiza.
👩🏽⚕️ Imibuzo eyengeziwe (ama-FAQ)
💬 Ingabe i-Dofetilide iwumuthi wokuhlaselwa yinhliziyo?
Cha! Lokhu akunikelwe ekuhlaselweni yinhliziyo! Isilinganiso senhliziyo yethu sigcinwa yizimpawu zikagesi. Kufanele sishaye ngesigqi esijwayelekile, njengesigubhu. Kodwa kwabanye abantu, amakamelo aphezulu enhliziyo (i-Atria) awashayi kahle, kodwa aqala ukuphaphazela (i-Atrial Fibrillation / AFib). I-Dofetilide (i-Tikosyn) umuthi okhethekile wokulwa nokuphazamiseka kwenhliziyo obuyisela lowo 'msindo wokuphaphazela/ophukile' esigqizeni esijwayelekile sesigubhu.
💬 Ngisho noma lo muthi ulungele i-AFIB, kungani unikezwa ngemva kokungeniswa esibhedlela?
Lokhu kuyinto eyingozi kakhulu futhi ekhethekile ngalo muthi! Awukwazi ukuthenga lo muthi (i-Dofetilide) ekhemisi bese uwuyisa ekhaya. Unikezwa 'ngezinsuku ezi-3 ezidingekayo esibhedlela (isikebhe se-ICU) futhi uxhunywe emshinini we-ECG'. Ngoba uma lo muthi udala isigqi senhliziyo, ngezinye izikhathi ungaphambuka futhi isigqi esisha esibulalayo (i-Torsades de pointes) singadalwa enhliziyweni futhi isiguli singafa ngokushesha. Yingakho ukuqapha kuyimpoqo.
💬 Yiziphi izinyathelo zokuphepha okufanele uzithathe uma uqhubeka nokuphuza i-Dofetilide ngemva kokubuya esibhedlela?
Ngisho noma usubuyele ekhaya, kufanele uphuze iphilisi ngesikhathi. Into ebaluleke kakhulu ukuthi ngenkathi uphuza lo muthi, ungathathi omunye 'umuthi' (ikakhulukazi amaphilisi esisu njengeCimetidine, amaphilisi okulwa ne-fungus njengeKetoconazole, kanye namanye ama-antibiotic) kanye 'nejusi le-grapefruit' ngaphandle kokutshela udokotela wakho! Uma wenza kanjalo, i-Dofetilide inganqwabelana emzimbeni wakho futhi ibangele inhliziyo yakho ime. Ngisho noma kuyisiraphu oyiphuzayo ngenxa yomkhuhlane, buza udokotela wakho nakanjani!
I- Dofetilide, Ukushaya kwenhliziyo, i-Arrhythmia, i-Atrial fibrillation, i-Atrial flutter, i-Tikosyn, isifo senhliziyo
💬 Comments (0)
Awekho amazwana athunyelwe okwamanje. Faka amazwana akho lapha okokuqala ngqa.
Engeza amazwana akho