Ingabe nawe uzizwa ukhathele ngaso sonke isikhathi? Uzizwa ungajabule kangako? Kungaba ngenxa yokuntuleka kwe-dopamine!

Ingabe ngezinye izikhathi uzizwa sengathi awunasithakazelo empilweni, ukhathele nje, futhi awutholi injabulo ezintweni ezazikulethela injabulo? Noma, awuzizwa sengathi uqala noma yini? Esinye isizathu salezi zinto kungaba ukwehla kwekhemikhali ebalulekile ebuchosheni bakho ebizwa ngokuthi i-dopamine. Ake sixoxe ngalokhu ngemininingwane ethe xaxa namuhla, akunjalo?

Iyini i-dopamine? Kungani ibalulekile?

Kalula nje, i-dopamine iyisithunywa samakhemikhali esibaluleke kakhulu ebuchosheni bethu. Kufana nombhali omncane ophethe ulwazi emuva naphambili ebuchosheni bethu. Kwezesayensi yezokwelapha, lokhu sikubiza ngokuthi i-neurotransmitter . I-Dopamine isebenza njenge-hormone emzimbeni wethu.

Le dopamine yiyo esiza ezintweni eziningi, njengenkumbulo yethu , isisusa, ukufunda, injabulo kanye nenduduzo (umvuzo), kanye nokulawula ukunyakaza komzimba . Cabanga ngakho, injabulo oyizwayo uma uqeda into enzima, ehlobene ne-dopamine.

Ngakho-ke, ukuntuleka kwe-dopamine kwenzeka lapho amazinga e-dopamine ehla khona emzimbeni wethu. Uma lokhu kwehla, izimo zezinzwa ezifana nesifo sikaParkinson noma izinkinga zengqondo ezifana nokucindezeleka zingase zivele. Ngezinye izikhathi, lokhu kuntuleka kwe-dopamine kungaholela ekuzibekeni engcupheni okungadingekile noma ekuluthweni okulula.

Kungani i-dopamine incipha emizimbeni yethu?

Kungaba nezizathu eziningana zalokhu. Ake sibheke eziyinhloko.

• Ukulimala kobuchopho: I-Dopamine iyikhemikhali ekhiqizwa ezindaweni ezithile zobuchopho bethu. Ngakho-ke, uma kwenzeka ingozi noma umonakalo ezindaweni lapho kukhiqizwa khona i-dopamine (isibonelo, ukulimala ekhanda), amazinga e-dopamine angancipha.
• Izinkinga ngokwamukela imiyalezo: Ngezinye izikhathi imizimba yethu ingase ingasabeli kahle ku-dopamine. Okusho ukuthi, uma ama-receptor asemaseli ezinzwa athola imiyalezo ye-dopamine engasebenzi kahle, umyalezo otholwe ku-dopamine awudluli kahle yize ukhona.
• Ezinye izimo zezokwelapha: Kunezinye izimo zezokwelapha ezihlobene ngqo nalokhu kuntuleka kwe-dopamine.
• Isibonelo, abantu abanesifo sikaParkinson balahlekelwa amangqamuzana ezinzwa ezingxenyeni ezithile zobuchopho, kanti amazinga e-dopamine nawo ayancipha.
• Enye into ukuthi abantu abaluthwe izidakamizwa ezifana ne-cocaine balimaze ama-receptor e-dopamine ebuchosheni babo, okunciphisa ukukhiqizwa kwe-dopamine, ngakho-ke badinga umuthi omningi ukuze bathole leyo njabulo.

Ziyini izimpawu ze-dopamine ephansi?

Uma amazinga e-dopamine ehla, ungathola izimpawu ezahlukahlukene. Kungenzeka ukuthi nawe uke wabhekana nalezi. Lezi zimpawu zingahluka kumuntu nomuntu, futhi zincike embangela.

Izimpawu ezivame ukubonakala:

• Ukunganaki , ukuntuleka kwesisusa. Njengokungathi akukho "ugqozi".
• Ukuzizwa ukhathele nje.
• Ubunzima bokugcina ingqondo yakho igxile (awukwazi ukugxila).
• Ukuzizwa ungenakuthula njalo, ucasukile, noma ukhathazekile.
• Iqiniso lokuthi awusatholi injabulo ezintweni owawuzijabulela.
• Ukuzizwa udabukile noma ucindezelekile ; ukulahlekelwa yithemba empilweni.
• Isifiso socansi esiphansi .
• Ukungalali kahle noma ukuphazamiseka kokulala.

Kukhona nezinye izimpawu ezihambisana nezimo ezithile zezokwelapha:

• Ukuthuthumela kwezingxenye zomzimba njengezandla (ikakhulukazi uma umile unganyakazi), ukulahlekelwa yibhalansi, ukuqina, kanye nokuqhaqhazela kwemisipha ( lokhu kungaba yizimpawu zesifo sikaParkinson) .
• Kukhona isifo esibizwa ngokuthi i-'Restless Legs Syndrome' , esibangela ukungakhululeki emilenzeni futhi senze kube nzima ukuma unganyakazi. Kungase futhi kube ngenxa yokuntuleka kwe-dopamine.
• Izinkinga zenkumbulo zesikhashana, ubunzima bokwenza imisebenzi yansuku zonke, kanye nokungakwazi ukuxazulula izinkinga ezilula ( lokhu kungase kube ngenxa yezinguquko zobuchopho ).
• Ukucasuka njalo, ukuzethemba okuphansi, ukukhathazeka, ukukhohlwa, ukuziphatha ngokuphamazela, kanye nokungakwazi ukuhlela imisebenzi ( lokhu kungaba izimpawu zesimo esibizwa ngokuthi i-Attention Deficit Hyperactivity Disorder (ADHD) ).
• Ukuzihlukanisa nabantu, ukulahlekelwa imizwa, kanye nokulahlekelwa injabulo ( lezi kungaba ezinye zezimpawu ze- schizophrenia ).
• Izinkinga zamathumbu, ikakhulukazi ukuqunjelwa okungapheli .

Njengoba ubona, kunezimpawu eziningi zokuntuleka kwe-dopamine. Izimpawu onazo zizoncika embangela eyinhloko. Yingakho kubalulekile ukubona udokotela ukuze uthole imbangela eqondile.

Unquma kanjani ngokunembile ukuthi une-dopamine ephansi?

Kukhona into ebalulekile okufanele uyiqonde lapha. Ukuntuleka kwe-Dopamine akuyona inkinga yezokwelapha eqondile. Okusho ukuthi, udokotela ngeke akunike ukuxilongwa ngoba une-dopamine ephansi. Eqinisweni, odokotela abavamile ukuhlola amazinga e-dopamine.

Ukuhlolwa kwegazi kukodwa akukwazi ukukutshela okuningi nge-dopamine. Isibonelo, yize ungalinganisa amazinga e-dopamine egazini lakho, akukwazi ukukutshela ukuthi ubuchopho bakho busabela kanjani ku-dopamine.

Kunalokho, udokotela wakho uzokwenza izinto ezifana nalezi:

• Babuza ngomlando wakho wezokwelapha .
• Babuza ngendlela ophila ngayo (njengokuthi usebenzisa utshwala noma izidakamizwa).
• Ngilalela ngokucophelela izimpawu zakho.
• Uzohlolwa .
• Ngemuva kwalokho, kuzokwenziwa izivivinyo ezidingekayo ngokusekelwe ezimpawini zakho.

Esebenzisa lolu lwazi kanye nemiphumela yokuhlolwa, udokotela uzonquma ukuthi unesifo esihlobene nokuntuleka kwe-dopamine.

Isibonelo, uma udokotela wakho esola ukuthi unesifo sikaParkinson, angase acele ukuhlolwa kokuthutha i-dopamine. Lolu uhlobo olukhethekile lokuskena. Ngokukhethekile, uhlobo lwe -Single-Photon Emission Computed Tomography (SPECT) . Lokhu kuhilela ukufaka into ekhipha imisebe egazini lakho bese uyiskena ukuze ubone ukuthi iya kanjani ebuchosheni bakho. Uma unesifo sikaParkinson, ukuskena kuzobonisa iphethini ethile ngenxa yamangqamuzana emizwa onakele kanye nokwehla kwe-dopamine ezindaweni ezithile zobuchopho bakho.

Izifo ezihlobene nokuntuleka kwe-dopamine ziphathwa kanjani?

Ukwelashwa kokuntuleka kwe-dopamine kuncike embangela eyinhloko. Ake sibheke ukuthi ezinye zezimo eziyinhloko zelashwa kanjani.

• Isifo sikaParkinson: Lokhu kuvame ukwelashwa ngomuthi obizwa ngokuthi i-levodopa . Kwezinye izimo, kusetshenziswa ama-dopamine agonists, njenge -Pramipexole (Mirapex®) , i-Ropinirole (Requip®) , noma i-Rotigotine (Neupro®) . Lawa ma-dopamine agonists asebenza njenge-dopamine, okwenza amangqamuzana ezinzwa aphendule ngendlela efanayo ne-dopamine.
• I-restless legs syndrome: Lesi simo siphinde selashwe ngama-dopamine agonists okukhulunywe ngawo ngaphambili i-Pramipexole (Mirapex®), i-Ropinirole (Requip®), noma i-Rotigotine (Neupro®).
• Ukucindezeleka: Lapho welapha ukucindezeleka, imithi ebizwa ngokuthi i-Selective Serotonin Reuptake Inhibitors (SSRIs) , njenge -Fluoxetine (Prozac®), inganikezwa. Lokhu kuthinta kokubili ama-neurotransmitter i-serotonin kanye ne-dopamine, okulungisa ukusebenza kwawo.
• Isifo Sokungakwazi Ukugxila (ADHD): Lesi simo singelashwa ngemithi efana ne -Methylphenidate (Concerta®, Ritalin®) . Le mithi ikhulisa umsebenzi we-dopamine.

Kungenzeka yini ukwandisa amazinga e-dopamine ngokwemvelo, ngaphandle kwemithi?

Uma ucabanga ukuthi amazinga akho e-dopamine aphansi, into yokuqala okufanele uyenze ukubona udokotela . Ungase ube nesimo esingelapheka esihlobene nokuntuleka kwe-dopamine. Uma ungaqiniseki, ungazama izindlela zemvelo zokwandisa amazinga akho e-dopamine. Kodwa khumbula ukuthi kudingeka ucwaningo olwengeziwe mayelana nokuthi ukudla neziphuzo zithinta kanjani ama-neurotransmitter njenge-dopamine.

Ukudla okusiza ekukhiqizeni i-dopamine:

• Yidla ukudla okucebile nge-magnesium kanye ne-tyrosine. Lezi izithako eziyisisekelo ezidingekayo ukuze kwenziwe i-dopamine. I-Tyrosine iyi-amino acid. Imuncwa emzimbeni bese iya ebuchosheni lapho iguqulwa khona ibe yi-dopamine.
• Ukudla okuthiwa kwandisa i-dopamine yilezi: inkukhu, ama-alimondi, ama-apula, ama-avokhado, ubhanana, i-beetroot, ushokoledi (ushokoledi omnyama ungcono), imifino eluhlaza, itiye eliluhlaza, ubhontshisi be-lima, i-oatmeal, amawolintshi, imbewu ye-chia, imbewu yesesame, imbewu yethanga, utamatisi, i-turmeric, ikhabe, kanye nokolweni.

Zibandakanye ezintweni ezikwenza ujabule futhi uphumule:

• Izinto ezinjengalezi kucatshangwa ukuthi zandisa amazinga e-dopamine. Izibonelo zifaka: ukuzivocavoca umzimba, ukuzindla, ukwenza i-yoga, ukubhucungwa umzimba, ukudlala nesilwane esifuywayo, ukuhambahamba emvelweni, noma ukufunda incwadi.

"Cabanga nje, injabulo oyizwayo uma ulalela ingoma oyithandayo, noma uma uhleka futhi uxoxa nomngane omuhle? Lezo yizinto ezisiza ekwandiseni i-dopamine. Ngakho thola isikhathi sezinto ezikwenza ujabule futhi ozijabulelayo."

Yiziphi izithasiselo ezandisa amazinga e-dopamine?

Kukhona futhi izithasiselo ezithi ziyasiza ekwandiseni amazinga e-dopamine. Kodwa-ke, kubaluleke kakhulu ukufuna iseluleko sezokwelapha ngaphambi kokuzithatha. Ungazisebenzisi lezi ngaphandle kokukhuluma nodokotela.

Ezinye zalezi ziyi:

• I-Tyrosine: I-Tyrosine iyi-amino acid yemvelo. I-Dopamine yenziwe nge-tyrosine.
• I-L-theanine: Lena enye into esiza ekukhiqizeni i-dopamine.
• I-Vitamin D, i-B5 kanye ne-B6: Lawa mavithamini abalulekile ekwenzeni i-dopamine.
• Ama-fatty acid e-Omega-3 (ama-fatty acid abalulekile e-Omega-3) .
• I-Magnesium `(i-Magnesium)` .

Yini enye okudingeka siyazi ngokuntuleka kwe-dopamine?

Amazinga aphansi e-dopamine awakwazi ukubhekwa ngendlela emnyama nemhlophe. Okusho ukuthi, lesi yisihloko esiyinkimbinkimbi kakhulu. Into ebalulekile ukuthi amazinga aphansi e-dopamine awabangeli izifo ngqo. Okusho ukuthi, kukhona ukuxhumana, kodwa i-dopamine ephansi ayibangeli izifo ngqo.

Okuyinkimbinkimbi kakhulu imiqondo yezimbangela kanye nokuxhumana. Isibonelo, kutholakale ukuthi abantu abanamazinga aphansi e-dopamine banamathuba amaningi okukhuluphala noma ukukhuluphala ngokweqile. Kuyaziwa futhi ukuthi ukudla esikudlayo kanye nokuzivocavoca esikwenzayo kuthinta indlela ubuchopho bethu obusebenzisa ngayo i-dopamine.

Kodwa umbuzo uwukuthi, ingabe kungenxa yemikhuba emibi yokudla (ukudla okungakhulisi i-dopamine) kanye nokuntuleka kwentshisekelo ekuzivocavoceni okwenza amazinga e-dopamine aphansi? Noma, ingabe kungenxa yamazinga aphansi e-dopamine ebuchosheni ukuthi "uhlelo lomvuzo" luyasebenza futhi sizizwa sengathi sidla ukudla okungenamsoco futhi singazivocavoci? Lokhu kufana nombuzo wenkukhu noma iqanda.

Ekugcineni, ayikho i-neurotransmitter eyodwa esebenza yodwa. Isibonelo, i-Dopamine isebenza eduze kakhulu ne-Serotonin. Ngakho-ke, ukuqonda la ma-neurotransmitter kuyinkimbinkimbi ngempela.

Ngakho-ke, yiziphi izinto okudingeka sizikhumbule kukho konke lokhu?

Kulungile, ngakho-ke ngithemba ukuthi uthathe okuthile kulokho esikhulume ngakho. Ake sikukhumbuze izinto ezibaluleke kakhulu futhi.

• Ukuntuleka kwe-dopamine kungathinta impilo yakho engokomzimba nengokwengqondo. Izimo eziningi, okuhlanganisa isifo sikaParkinson, i-restless legs syndrome, ukucindezeleka, i-schizophrenia , kanye ne-ADHD, zihlotshaniswa namazinga aphansi e-dopamine.
• Kukhona izindlela zokwelapha ezingasiza ekuphatheni lezi zimo. Futhi, yize ungazama izindlela zemvelo zokwandisa amazinga e-dopamine, kubalulekile ukukhuluma nodokotela wakho ngaphambi kokwenza noma yini.
• Uma unalezi zimpawu, ungesabi noma ube namahloni okubona udokotela. Bazokusiza ukuthola imbangela futhi bakutshele ukuthi wenzeni.
• Khumbula, awuwedwa, futhi akukaze kube sekwephuzile ukucela usizo. Into ebaluleke kakhulu ukunakekela inhlalakahle yakho yengqondo neyomzimba.

I - Dopamine, ukuntuleka kwe-dopamine, ubuchopho, ama-neurotransmitters, isifo sikaParkinson, ukucindezeleka, injabulo, impilo yengqondo, i-ADHD