Uke wezwa ngalo mdlavuza ongavamile obizwa ngokuthi i-DSRCT? (Desmoplastic Small Round Cell Tumor) Ake sixoxe ngemininingwane!

Namuhla sizokhuluma ngohlobo lomdlavuza oluyinkimbinkimbi futhi olungavamile kakhulu. Lubizwa ngokuthi i-Desmoplastic Small Round Cell Tumor, noma i-DSRCT njengoba lubizwa kanjalo phakathi kodokotela. Kungenzeka ukuthi awukaze uzwe ngaleli gama ngaphambili, ngoba yisifo esithinta abantu abambalwa kakhulu. Kodwa ukuqaphela izimo ezinjalo kungaba yinto ebaluleke kakhulu kithi nakubathandekayo bethu.

Ngakho-ke iyini le DSRCT?

Kalula nje, i-DSRCT yisifo esibangela izimila ezinomdlavuza ezikhula ngokushesha kakhulu . Lokhu kungokwesigaba se- soft tissue sarcoma . Lokhu kusho ukuthi lezi zimila zingavela ezingxenyeni ezithambile zomzimba wethu ezingenamathambo, njengemisipha, amafutha, kanye nemizwa. Kodwa-ke, ku-DSRCT, lezi zimila zikhula kakhulu elweleni elimboza isisu sethu (i-peritoneum) . Cabanga ngakho, lolu ulwelwesi oluncane oluvikela izitho ezifana nesibindi namathumbu ngaphakathi kwesisu sethu. Ngakho-ke yilapho lawo maseli omdlavuza ehlukana khona ngokushesha futhi aqale ukwakha izimila.

Nakuba lesi sifo singakhula kunoma ubani, sivame ukubonakala kakhulu ezinsizweni eziphakathi kweminyaka engama-20 nengama-30. Akumangazi lokho? Kunezindlela zokwelapha lokhu, futhi ngezinye izikhathi izimpawu ziyanyamalala futhi lesi sifo singatholakala ezivivinyweni, okungukuthi, ekuphumuleni . Kodwa-ke, into edabukisayo ukuthi lesi sifo esincishisiwe ngale ndlela cishe sizophinde sivele, okungukuthi, sizophinde sivele .

Kungavamile kangakanani lesi sifo esibizwa ngokuthi i-DSRCT?

Kuyivelakancane kakhulu kangangokuthi awukwazi ngisho nokukucabanga. Selokhu abacwaningi bathola lesi sifo okokuqala ngo-1989, kubikwe ukuthi sikhona kubantu abayizigidi eziyi-1 emhlabeni jikelele. Lokho kusho ukuthi, uma kuqhathaniswa nenani labantu baseSri Lanka, kunzima ukuthola umuntu ngisho kanye eminyakeni embalwa. Kuyivelakancane kangako.

Ziyini izimpawu ze-DSRCT?

Esikhathini esiningi, izimila ezikhula ngaphakathi esiswini azibangeli izimpawu ezinkulu kuze kube yilapho zikhula kakhulu, zithathe isikhala esiswini, futhi zithinte uhlelo lokugaya ukudla. Kodwa-ke, kunezimpawu ezimbalwa ezivamile ezingabonakala:

• Ubuhlungu besisu: Ubuhlungu besisu obuqhubekayo, ngezinye izikhathi obuba bubi kakhulu.
• Ukuqunjelwa: Ubunzima bokuhamba kwamathumbu njalo.
• Uhudo: Ukuhlanza.
• Isisu esivuvukile: Isisu sibonakala sikhukhumele futhi sivuvukile.
• Isicanucanu nokuhlanza: Ukulahlekelwa yisifiso sokudla okuhambisana nesicanucanu nokuhlanza.
• Ukwehla kwesisindo okungachazeki: Ukwehla kwesisindo ngokuzumayo ngaphandle kwemingcele ethile yokudla.

Bheka manje, lezi zinto ezifana nokuqunjelwa, isifo sohudo, kanye nesicanucanu zingabonakala nasezifweni ezincane esivame ukuzithola, akunjalo? Ngakho-ke akuwona umqondo omuhle ukwesaba isifo esingathi sína ngoba nje unalezi zimpawu.Kodwa-ke, uma lezi zimpawu ziqhubeka izinsuku ezingaphezu kwezimbalwa noma ziba zimbi kakhulu, kuwukuhlakanipha ukubonana nodokotela.

Kungani kwenzeka le DSRCT? Iyini imbangela?

Abacwaningi bathole ukuthi i-DSRCT ibangelwa ushintsho kuma -chromosome emaseli ethu. Lolu shintsho ludala i-gene engavamile ebizwa ngokuthi i-EWS-WT1 . Le gene inesibopho sokukhula kwamaseli omdlavuza. Kodwa-ke, akukaziwa kahle ukuthi kungani la ma-chromosome eshintsha ngale ndlela. Leso yisici esiyinkimbinkimbi kakhulu salezi zifo.

Odokotela bakuthola kanjani lesi simo se-DSRCT?

Ukuze kutholakale lokhu, odokotela bahlanganisa izivivinyo eziningana ukuze bafinyelele esiphethweni:

• Ukuhlolwa komzimba: Okokuqala, udokotela uzothinta isisu sakho ukuze abone ukuthi kukhona yini ongakuzwa, njengezigaxa.
• Ukuhlolwa kwezithombe: Lokhu kufaka phakathi ukuhlolwa kwe-CT , ukuhlolwa kwe-MRI , kanye nokuhlolwa kwe-ultrasound . Lokhu kungasiza ekunqumeni ukuthi kukhona yini izimila ku-peritoneum, ukuthi zikhulu kangakanani, nokuthi ngabe zisakazekele kwezinye izindawo.
• Ukuhlolwa kofuzo: Lokhu kuhlolwa kusiza ukuqinisekisa ukuthi kukhona yini ukuguqulwa kofuzo kwe-EWS-WT1 okukhulunywe ngakho ngaphambilini. Yilokhu okungabona ngokunembile ukuthi kuyi-DSRCT.

Yiziphi izindlela zokwelapha i-DSRCT?

Odokotela basebenzisa izindlela eziningana ukwelapha i-DSRCT. Eziyinhloko yilezi:

• Ukuhlinzwa: Ukususwa kwezimila eziningi zomdlavuza ngangokunokwenzeka ngokuhlinzwa.
• I-HIPEC (Hyperthermic Intraperitoneal Chemotherapy): Lokhu kuyindlela yokwelapha ekhethekile kancane. Ngemva kokuba isimila sisusiwe ngokuhlinzwa, imithi ye-chemotherapy eshisayo ifakwa esiswini ukuze kubhujiswe noma yimaphi amangqamuzana omdlavuza asele.
• Ukwelashwa ngamakhemikhali: Ukwelashwa okunamandla okunikezwa umzimba ukuze kubhujiswe amangqamuzana omdlavuza.
• Ukwelashwa ngemisebe: Ukusetshenziswa kwemisebe enamandla amakhulu ukubhubhisa amangqamuzana omdlavuza.

Lokhu kwelashwa kungafaka lesi sifo esimeni sokululama , okusho ukuthi azikho izimpawu futhi akukho ukuhlolwa okungabona lesi sifo. Kodwa-ke, lokhu kukhululeka ngokuvamile akuhlali isikhathi eside. Lesi sifo singaphinde sibuye , ngakho-ke kungase kudingeke kuqalwe ukwelashwa okusha noma izindlela ezahlukene zokwelapha.

Okubalulekile: Kungakhathaliseki ukuthi uthola ukwelashwa okunjani, ukunakekelwa kokunciphisa ubuhlungu eqenjini lakho lezokwelaphaQiniseka ukuthi ubuza ngakho. Lokhu kwenzelwa ukunciphisa ubuhlungu obungokomzimba kanye nokucindezeleka kwengqondo okubangelwa yilesi sifo futhi kukunikeze ukwesekwa kwezokwelapha, kwezenhlalo, kanye nokwengqondo okudingayo ukuze uphile nalesi sifo ngangokunokwenzeka. Lokhu akuyona indlela yokwelapha elapha umdlavuza, kodwa ingathuthukisa kakhulu ikhwalithi yempilo yakho.

Ingabe ikhona imiphumela emibi yokwelashwa?

Yebo, ukuhlinzwa, i-chemotherapy, kanye nokwelashwa ngemisebe konke kungabangela imiphumela emibi. Ngemva kokuhlinzwa ukuze kususwe izimila ze-DSRCT, ungase ube nemiphumela emibi njengokusabela ku-anesthesia ejwayelekile noma ukopha. Imiphumela emibi evamile yokwelashwa ngemisebe kanye ne-chemotherapy ihlanganisa:

• Uhudo
• Ukukhathala
• Isicanucanu nokuhlanza

Le miphumela emibi ayiveli ngendlela efanayo kuwo wonke umuntu, abanye abantu bangase babe nenkinga encane, abanye bangase babe nenkinga enkulu. Udokotela wakho uzokwazisa ngalokhu.

Iyini i-prognosis yesiguli ku-DSRCT?

Lena yinto enzima kakhulu ukukhuluma ngayo, futhi wonke umuntu afuna ukuyazi. Ukubikezela yilokho odokotela abathi ungakulindela ngemva kokwelashwa. Benza lesi sinqumo ngokusekelwe ezicini ezifana nokuthi umdlavuza ukuphi, ukuthi usakazeke yini, nokuthi ungakanani owasuswa ngesikhathi sokuhlinzwa.

Ngenxa yokuthi i-DSRCT ingumdlavuza ongavamile, ucwaningo luncane kakhulu ngayo. Ngakho-ke kunzima kodokotela ukusho ngqo ukuthi yini ongayilindela noma ukuthi ungaphila isikhathi esingakanani. Lokhu kuyadabukisa ngempela.

Idatha yamanje ikhombisa ukuthi izinga lokusinda kweminyaka emihlanu le-DSRCT ngemva kokuxilongwa liphakathi kuka-15% no-38% . Lokhu kusho ukuthi akuwona wonke umuntu ozolulama. Kodwa-ke, olunye uhlaziyo lubonise ukuthi iphesenti elincane leziguli ezine-DSRCT esakazekile zelapheka ngokuphelele ngokwelashwa. Futhi, cishe ama-60% alabo abelashwa ngaphambi kokuba umdlavuza usakazeke bayaphila ngemva kweminyaka emihlanu. Ngakho-ke, ungabona ukuthi kubaluleke kangakanani ukuwuthola kusenesikhathi bese uqala ukwelashwa ngokushesha, akunjalo?

Ngingazinakekela kanjani ngalesi simo?

I-DSRCT ingumdlavuza ongavamile futhi onzima. Ungabuya ezinyangeni noma eminyakeni ngemva kokwelashwa. Ukuphila nokwesaba ukuthi umdlavuza uzobuya akulula. Kodwa-ke, kunezinto ezimbalwa ezingakusiza kulolu hambo:

• Qonda isimo sakho: Ngenxa yokuthi i-DSRCT ayivamile, kungaba nzima ukuthola ulwazi olunembile nolusesikhathini ngayo. Ngakho-ke, ungalokothi unqikaze ukubuza ithimba lakho lezokwelapha ukuthi yini ongayilindela. Bakwazi kangcono wena nesimo sakho.
• Buza mayelana nokuhlanganyela ezivivinyweni zemitholampilo:Abacwaningi bahlola izindlela ezintsha zokwelapha i-DSRCT. Buza udokotela wakho ukuthi ungabamba iqhaza yini esivivinyweni somtholampilo .
• Cabanga ngokusinda komdlavuza: Kusukela ngosuku owatholakala ngalo, ubulokhu ungumlwi futhi usindile impilo yakho yonke. Buza ithimba lakho lezokwelapha ngezinhlelo ezikhethekile zabantu abanomdlavuza ophindaphindayo.
• Thola ukwesekwa: Buza ithimba lakho lezokwelapha ngamaqembu okusekela abantu abanomdlavuza ongavamile. Ukuchitha isikhathi nokukhuluma nabantu abadlula kokuhlangenwe nakho okufanayo nawe noma abanokuhlangenwe nakho okufanayo kungasiza ekunciphiseni isizungu sokuphila ne-DSRCT.

Kufanele ngiphinde ngimbone nini udokotela wami?

I-DSRCT yisimo esingase siphinde sibuye. Ngakho-ke, udokotela wakho angase ancome ukuhlolwa kwezithombe (njenge -CT scan) njalo ezinyangeni ezintathu kuya kweziyisithupha ukuze kuhlolwe izimila ezintsha olwelwesini lwesisu noma kwenye indawo. Kubaluleke kakhulu ukungaphuthelwa yilokhu kuhlolwa okulandelayo .

Yimiphi imibuzo okufanele ngiyibuze udokotela wami?

Ngesikhathi esinjengalesi, ungase ube nemibuzo eminingi. Kunzima ukuqonda yonke into ngesikhathi esisodwa. Ungesabi, funda konke lokhu kancane kancane. Nansi eminye imibuzo ongayibuza njengesiqalo:

• Ngingaqiniseka kanjani ukuthi izimpawu zami zibangelwa yilesi simo esibizwa ngokuthi i-DSRCT?
• Ingabe lokhu kungalapheka ngokuphelele ngokwelashwa?
• Yikuphi ukwelashwa okuncomayo?
• Iyini imiphumela emibi yalezo zindlela zokwelapha?
• Ingabe kufanele ngicabangele ukuhlanganyela esivivinyweni somtholampilo?

Uma kutholakale ukuthi une-DSRCT, kungaba yisenzakalo esishintsha impilo. Ungase uzizwe ukhungathekile yimizwa. Ungase ukhathazeke ngokuthi kuzokwenzekani ngokulandelayo, ukuthi ukwelashwa kuzoba njani, nokuthi ikusasa lakho liphetheni. Kungase futhi kube yinto ekhungathekisayo ukuthola ulwazi mayelana nesifo esithinta iphesenti elincane labantu emhlabeni.

Ithimba lakho lezokwelapha liyayiqonda yonke le mizwa. Bazokunika isikhathi esiningi ngangokunokwenzeka ukuze uqonde ukuthi kwenzekani kuwe nokuthi yini engase yenzeke ngokulandelayo. Ungesabi ukukhuluma nabo futhi ubuze noma yimiphi imibuzo onayo.

Umyalezo Wokugcina Wokuya Nasekhaya

Kuvamile ukuzizwa ukhungathekile uma ufunda ngalesi simo esibizwa ngokuthi i-DSRCT. Kodwa-ke, khumbula la maphuzu:

• I-DSRCT ingumdlavuza ongavamile kakhulu futhi oyingozi. Kubalulekile ukuqaphela lokho kuqala.
• Qaphela izimpawu. Uma unezinhlungu zesisu ezingapheli, ukuqunjelwa, noma ukwehla kwesisindo, funa iseluleko sezokwelapha.
• Ukutholwa kusenesikhathi kanye nokwelashwa okusheshayo kubalulekile. Lokhu kungashintsha indlela isifo esiqhubeka ngayo ngezinga elithile.
• Awuwedwa.Ithimba lezokwelapha, umndeni, kanye namaqembu okusekelana akhona ukukusiza.
• Cabanga ngokunakekelwa kokunciphisa ubuhlungu. Lokhu kungathuthukisa kakhulu izinga lempilo yakho.
• Ungesabi ukubuza imibuzo. Qiniseka ukuthi uzwa konke ngokucacile kudokotela wakho.

Sithemba ukuthi lolu lwazi lukusizile ukuthi uqonde lesi simo esingavamile. Khumbula, ukuqwashisa kungamandla amakhulu okubhekana nanoma iyiphi inselele.

I- DSRCT, Isimila Esincane Esiyindilinga Seseli Eliyindilinga Eliyi-Desmoplastic, Umdlavuza, Umdlavuza Wesisu, Umdlavuza Ongavamile, Izimpawu Zomdlavuza, Ukwelashwa Komdlavuza, Umdlavuza We-Peritoneum