Ingabe wena noma othile omaziyo wake watshelwa udokotela ukuthi athathe umuthi "wokunciphisa igazi"? Kungenzeka ukuthi wesaba kancane lapho uzwa lelo gama. Kungenzeka ukuthi wacabanga, "O, ingabe igazi lami lizoncipha?" Kodwa empeleni lezi izidakamizwa ezibaluleke kakhulu ezingasindisa izimpilo uma zisetshenziswa kahle. Namuhla sikhuluma ngelinye lala mithi emisha nethuthukisiwe. Yi-Factor Xa Inhibitors.
Kalula nje, ziyini lezi zithiyo ze-Factor Xa?
Ama-Factor Xa Inhibitors ayizinhlobo zemithi evimbela igazi lakho ukuthi lingajiyi ngendlela engavamile. Siwabiza ngokuthi “ama-blood thinners” ngamagama avamile. Kodwa odokotela bawabiza ngokuthi “ama-Direct Oral Anticoagulants” noma “ama-DOAC”. Angasetshenziswa isikhathi eside ukwelapha i-blood clot eseyakhekile, kanye nokuvimbela ama-clot esikhathini esizayo.
Kunezinhlobo eziningana zemithi eyinhloko eziwela kulesi sigaba. Udokotela wakho kungenzeka ukuthi ukunike enye yale mithi.
- I-Apixaban
- I-Betrixaban
- I-Edoxaban
- I-Rivaroxaban
- I-Fondaparinux (Leli akulona iphilisi. Liwumjovo womjovo ngemithambo yegazi)
Lo muthi usetshenziselwa ziphi izimo?
Lolu hlobo lomuthi lusetshenziselwa ukwelapha nokuvimbela izimo eziningana ezibalulekile zezokwelapha. Cabanga ngomthambo wegazi emzimbeni wethu njengepayipi elithwala amanzi. Uma ihlule legazi libhajwa ndawana thize kulelipayipi, lingabangela izinkinga ezinkulu. Yilokho lomuthi osiza ukukuvimbela.
Ungathola umbono omuhle ngalokhu kuthebula elingezansi.
| Isimo eselashwa/esivinjiwe | Incazelo elula |
|---|---|
| Ukunciphisa ingozi yokushaywa yisifo sohlangothi | Abanye abantu abanokushaya kwenhliziyo okungajwayelekile (i-atrial fibrillation) bangaba namahlule egazi emithanjeni eholela ebuchosheni futhi babangele isifo sohlangothi. Lo muthi unciphisa leyo ngozi. |
| Ukwelapha i-Deep Vein Thrombosis (DVT) | Lesi yisimo lapho kwakheka khona amahlule egazi emithanjeni ejulile emzimbeni, ikakhulukazi emilenzeni. Lo muthi usiza ekuncibilikiseni lawo mahlule. |
| Ukwelashwa kwe-Pulmonary Embolism (PE) | Lesi simo senzeka lapho ihlule legazi emlenzeni liphuka bese libhajwa emthanjeni emaphashini. Lokhu kuyingozi kakhulu. Lo muthi uyindlela yokwelapha nalokho. |
| Ukuvimbela i-Venous Thromboembolism (VTE) | Leli igama elinikezwa kokubili i-DVT kanye ne-PE ndawonye. Lo muthi uvimbela lezi zimo ukuthi zingaphinde zivele. |
| Ukunciphisa ingozi yesifo senhliziyo nesifo semithambo yegazi | Lo muthi uwusizo nakubantu abanesifo semithambo yenhliziyo kanye nesifo semithambo yegazi engaphandle. |
| Ngemva kokuhlinzwa okukhulu | Ngemva kokuhlinzwa kokufakelwa inqulu noma idolo, usengozini enkulu yokuba namahlule egazi ngoba uhlala embhedeni. Lo muthi unikezwa ukuvimbela lokhu. |
Lo muthi uhluke kanjani ku-Warfarin?
Kungenzeka ukuthi uke wezwa ngomuthi i-Warfarin. Futhi umuthi omuhle kakhulu ovimbela ukujiya kwegazi futhi ususetshenziswe iminyaka eminingi. Kodwa inselele enkulu kumuntu othatha i-Warfarin ukuthi ahlolwe igazi njalo . Lokho kusho ukuthi uya esibhedlela kanye ngenyanga, mhlawumbe kabili ngesonto, ukuze unikeze igazi futhi uhlolwe ngendlela elinganisa isikhathi esithathayo ukuze igazi lijiye. Ngokusekelwe kuleyo miphumela, udokotela uzokwandisa noma anciphise umthamo womuthi.
Enye yezinzuzo ezinkulu ze-Factor Xa Inhibitors ukuthi azidingi ukuhlolwa kwegazi njalo, okunciphisa kakhulu ubunzima besiguli.
Lo muthi usebenza kanjani emzimbeni?
Lokhu kuyathakazelisa kakhulu. Cabanga ngokwakheka kwehlule legazi njengenqubo yokuhlanganisa efektri. Kunezinyathelo eziningi ezihilelekile. Amaprotheni ayahlangana ukuze akhe ihlule legazi.
I-Factor Xa iyiprotheni eyisisebenzi esibaluleke kakhulu kuleyo "nqubo yokuhlanganisa." Lokho okwenziwa yilo muthi ukuphazamisa umsebenzi waleyo protheni ebizwa ngokuthi i-Factor Xa.. Kufana nokuthatha ikhefu emsebenzini isikhashana. Bese yonke inqubo yokujiya kwegazi ibuyela esimweni sayo esijwayelekile. Lokho kusho ukuthi amahlule egazi angadingekile ayayeka ukwakheka. Uyaqonda?
Kuyoze kube nini uthatha lo muthi?
Lokhu kuncike esizathwini osithathayo umuthi. Kuyahlukahluka kumuntu nomuntu.
- Uma unenhliziyo engajwayelekile (i-atrial fibrillation): Kungase kudingeke ukuthi uthathe lo muthi impilo yakho yonke.
- Uma une-blood clot emthanjeni (VTE): Ngokuvamile kuthatha phakathi kwezinyanga ezi-3 nezi-6.
- Uma une-blood clot emlenzeni wakho (DVT) noma emaphashini (PE): Kuzothatha cishe izinyanga eziyisithupha.
- Uma ngemuva kokuhlinzwa kokufakelwa idolo: Izinsuku ezingu-12 kuphela ngemva kokuhlinzwa.
- Ngemva kokuhlinzwa kokufakelwa inqulu: Kuzothatha cishe izinsuku ezingu-35 ngemva kokuhlinzwa.
Into ebaluleke kakhulu ukuphuza imithi yakho njengoba nje udokotela wakho ekutshelile. Ungalokothi uyeke ukuthatha imithi yakho ngaphandle kokubuza udokotela wakho.
Ziyini izingozi nemiphumela emibi yale mithi?
Njenganoma yimuphi umuthi, kunezingozi ezithile. Ngenxa yokuthi ivimbela ukujiya kwegazi, ingozi enkulu ngale mithi ukopha kakhulu kunokujwayelekile .
- Ukopha okukhulu: Akuvamile kakhulu, ukopha kungenzeka ngaphakathi kobuchopho noma ezindaweni ezifana nesisu noma amathumbu. Lokhu kungaba nzima ukulawula. Kodwa-ke, manje sekukhona imithi ekhethekile ebizwa ngokuthi "ama-reversal agents" (isib. i-andexanet alfa) engaguqula imiphumela yale mithi. Odokotela bayayisebenzisa uma kwenzeka ukopha okusongela ukuphila.
- Imiphumela emibi emincane:
- Ngisho noma uthola ukulimala okuncane emzimbeni wakho, ungase uqaphele amabala egazi (imivimbo) kaningi.
- Abanye abantu bangase babe nokuvuvukala kwesikhumba .
Into ebalulekile ukuthi, le ngozi ayiyona yodwa kule mithi. Noma yimuphi umuthi wokunciphisa igazi unale ngozi. Ngakho ungesabi. Kodwa, kubaluleke kakhulu ukuqaphela.
Kufanele uqaphele kanjani lapho uthatha imithi?
Uma uthatha lo muthi, kubaluleke kakhulu ukuzivikela ezingozini nasekulimaleni ngangokunokwenzeka. Ngisho nokusikeka okuncane kungaba nzima ukuyeka ukopha. Nanka amanye amathiphu alula angakusiza.
| Okufanele ngikwenze | Kungani lokho kubalulekile? |
|---|---|
| Qaphela kakhulu uma usebenzisa amathuluzi abukhali (imimese, izikele). | Uma uzisika isandla sakho, kungaba nzima ukuvimba ukopha. Qaphela ngemimese lapho ugeza izitsha. |
| Uma ushefa, sebenzisa i-razor kagesi esikhundleni se-razor ene-blade. | Ingozi yokuzisika ngensingo ingancishiswa. |
| Gqoka amagilavu nezicathulo uma usebenza engadini. | Ngisho nenxeba elivela entweni efana negeja noma iva lingabangela ukopha okukhulu. |
| Qaphela izingozi ezingase zishelele futhi ziwe (omata, izintambo phansi) ngaphakathi endlini. | Ukulimala okubangelwa ukuwa, ikakhulukazi uma ushayeka ekhanda, kungaba yingozi. |
Ngingambona nini udokotela?
Uma uhlangabezana nanoma yiziphi izimpawu ezilandelayo ngenkathi uthatha lo muthi, shayela udokotela wakho ngokushesha, noma uye egumbini lezimo eziphuthumayo esibhedlela esiseduze (i-ETU).
- Ukopha okukhulu okungenakuvinjelwa: Uma ungakwazi ukuvimba ukopha okuvela enxebeni, ekhaleni, emlonyeni, noma ezinsinini.
- Ukuwa: Uma uwela ndawana thize, ikakhulukazi uma ushayeka ekhanda, kungenzeka ukuthi uphuma igazi ngaphakathi ngisho noma kungekho ukulimala okubonakalayo.
- Uma kukhona igazi esitulweni (indle emnyama noma ebomvu ngokumnyama).
- Uma uhlanza igazi (njengekhofi eligayiwe noma elibomvu).
- Ubuhlungu obukhulu esifubeni, ekhanda, noma esiswini.
- Ubunzima bokuphefumula.
- Ukuqubuka okungazelelwe.
Lo muthi ube usizo olukhulu kubantu abaningi ngoba abadingi ukuhlolwa igazi labo kaningi njengeWarfarin. Kodwa-ke, lo muthi awufanele wonke umuntu. Khuluma nodokotela wakho ukuze unqume ukuthi yimuphi umuthi okulungele wena. Kungakhathaliseki ukuthi uthatha muphi umuthi, kubalulekile ukulandela imiyalelo kadokotela wakho ngqo.
Umlayezo Wokuya Nawe Ekhaya
- Ama-Factor Xa Inhibitors ayiqembu elisha nelisebenzayo lemithi evimbela ukujiya kwegazi.
- Uma kuqhathaniswa nemithi emidala efana neWarfarin, akudingeki ukuthi uhlolwe igazi njalo uma uthatha le mithi. Lokho kulula kakhulu.
- Ingozi enkulu yale mithi ukopha ngokweqile, ngakho-ke kubaluleke kakhulu ukuzivikela ekulimaleni.
- Ungalokothi uqale, uyeke, noma ushintshe umthamo wanoma yimuphi umuthi ngaphandle kweseluleko sikadokotela wakho.
- Uma uzwa ukopha okungajwayelekile noma ezinye izimpawu eziyingozi, funa iseluleko sezokwelapha ngokushesha.
💬 Comments (0)
Awekho amazwana athunyelwe okwamanje. Faka amazwana akho lapha okokuqala ngqa.
Engeza amazwana akho