Isifo sikashukela siyinkinga yezempilo abantu abaningi emphakathini wethu ababhekene nayo namuhla. Ikakhulukazi, isifo sikashukela sohlobo lwesibili singaba khona kunoma yimuphi ubudala. Ngalesi simo, ingozi yokuthola ezinye izinkinga zempilo iyanda. Ngakho-ke, kunezinhlobo eziningi zemithi odokotela abayincomayo ukulawula lesi sifo. Omunye umuthi onjalo yiFarxiga. Namuhla, kulesi sihloko, sizokhuluma ngezinto ezibaluleke kakhulu okudingeka uzazi uma udokotela wakho ekubhalela lo muthi.
I-Farxiga isebenza kanjani emzimbeni?
Lo muthi, oza ngaphansi kwegama lomkhiqizo iFarxiga, uqukethe isithako esisebenzayo i-dapagliflozin . Lokhu kungokwesigaba semithi ebizwa ngokuthi ama-SGLT2 inhibitors. Manje ake sibone ukuthi lokhu kuyini ngamagama alula.
Cabanga ngezinso zethu njengezihlungi ezimbili ezinkulu. Lezi zihlungi zihlanza igazi lethu futhi zisuse izinto ezingafuneki ngomchamo. Ngale ndlela, ushukela (i-glucose) egazini nayo iyahlungwa emchameni. Kodwa umzimba wethu uhlakaniphile kakhulu. Ukusebenzisa iphrotheni ebizwa ngokuthi i-SGLT2 ezinso, kuphinde kumunce ushukela ozama ukungena emchameni. Umuntu onesifo sikashukela usevele unamazinga aphezulu kashukela emzimbeni wakhe. Ngakho-ke ukumunca ushukela kabusha akuyona into enhle.
I-Farxiga isebenza ngokuvimbela isenzo seprotheyini ye-SGLT2 . Lokhu kusho ukuthi ushukela awusamuncwa emzimbeni, kodwa kunalokho ukhishwa emchameni. Kalula nje, umsebenzi oyinhloko walo muthi ukulawula amazinga kashukela egazini ngokususa ushukela omningi emzimbeni wakho ngomchamo wakho .
Iyini imiphumela yalo muthi?
I-Farxiga iye yacwaningwa kabanzi emhlabeni wonke. Lezi zifundo zithole ukuthi iyasebenza kakhulu ekwehliseni amazinga kashukela egazini, kokubili uma isetshenziswa yodwa noma ihlanganiswa neminye imithi yesifo sikashukela.
I-Farxiga isetshenziswe kanye nemithi elandelayo evame ukusetshenziswa ukwelapha isifo sikashukela:
- I-Metformin
- Ama-Sulfonylurea (isib., i-Gliclazide, i-Glimepiride)
- Ama-agonist e-GLP-1 receptor
- I-insulini
- Izithibi ze-DPP-4
- I-Thiazolidinediones
Into eyinhloko ebhekwayo kulezi zifundo inani elibizwa nge -HbA1c (i-hemoglobin A1c). Kalula nje, i-HbA1c iyizinga lakho elijwayelekile likashukela egazini ezinyangeni ezi-2-3 ezedlule . Kufana 'nekhadi lombiko' lokulawula kwakho isifo sikashukela. Ezifundweni eziningi, abantu abasebenzisa i-Farxiga babenamazinga e-HbA1c aphansi kakhulu.
Kuthatha isikhathi esingakanani ukubona imiphumela?
Amazinga kashukela egazini lakho azoqala ukwehla cishe ngokushesha ngemva kokuqala ukuthatha i-Farxiga. Uma ungumuntu ohlola ushukela egazini lakho ekhaya, uzobona umehluko omkhulu phakathi kwamasonto amane okuqala.Ungakubona. Kodwa kuthatha isikhathi ukuthi inani le-HbA1c lehle. Ngenxa yokuthi isilinganiso sezinyanga ezingu-2-3, kungathatha cishe amasonto angu-8 kuya kwangu-12 ukubona ushintsho kulelo nani.
Ingabe zikhona ezinye izinzuzo ngaphandle kokunciphisa ushukela?
Yebo! Nakuba umsebenzi oyinhloko we-Farxiga ukulawula ushukela egazini, ucwaningo luye lwabonisa ukuthi inezinzuzo eziningana ezengeziwe. Lokhu kubaluleke kakhulu kumuntu onesifo sikashukela.
| Inzuzo eyengeziwe | Incazelo elula |
|---|---|
| Ukwehlisa isisindo | Leli akulona iphilisi lokwehlisa isisindo. Kodwa-ke, njengoba ushukela ukhishwa emchameni, amakhalori akulowo shukela nawo ayakhishwa emzimbeni. Ngakho-ke, kutholakale ukuthi abantu abaphuza leli philisi balahlekelwa cishe yi-1.5 - 3.5 kg (3.5 - 7 pounds). |
| Ukwehla komfutho wegazi | Lona akuwona umuthi wokwelapha umfutho wegazi. Kodwa uma ushukela ukhishwa emchameni, amanzi amancane nawo ayakhishwa emzimbeni. Lokhu kubangela ukwehla okuncane komfutho wegazi. |
| Ukunciphisa ukulaliswa esibhedlela ngenxa yesifo senhliziyo | Lo muthi uboniswe ukuthi unciphisa ingozi yokulaliswa esibhedlela ngenxa yokwehluleka kwenhliziyo uma unesifo senhliziyo noma izinto ezibangela lokho (i-cholesterol, umfutho wegazi ophakeme, ukubhema). |
| Ukuvikelwa kwezinso | Isifo sikashukela singalimaza izinso zakho ngokuhamba kwesikhathi. Uma unesifo sezinso esingamahlalakhona, i-Farxiga ingasiza nasekuvimbeleni ukuthi singabi sibi kakhulu. |
Iyini imiphumela emibi yalo muthi?
Njenganoma yimuphi umuthi, iFarxiga ingabangela imiphumela emibi emincane. Kubalulekile ukuqaphela lokhu.
1. Ukutheleleka Kwemvubelo Yesitho Sangasese
Lona umphumela ovame kakhulu we-Farxiga. Ushukela omningi emchameni udala indawo enhle yokukhula kwesikhunta esifana nemvubelo. Lokhu kuvame kakhulu kwabesifazane.
- Izimpawu: Ukuluma endaweni yesitho sangasese, uketshezi olunuka kabi.
- Indlela yokuphatha?
- Gqoka izingubo zangaphansi zikakotini.
- Gcina indawo yangasese yomile njalo.
- Khuluma nodokotela wakho bese uthola ukwelashwa okufanele.
2. I-Hypoglycemia - Amazinga kashukela egazini aphansi kakhulu
Lesi simo asivamile ukwenzeka uma iFarxiga ithathwa yodwa. Kodwa-ke, uma uthatha iFarxiga ne-insulin noma i-sulfonylurea (isb., i-Gliclazide) , amazinga kashukela egazini lakho angase abe phansi kakhulu.
- Izimpawu: ukujuluka, ukuthuthumela, indlala enkulu, isiyezi.
- Ukuphathwa: Uma uqala iFarxiga, udokotela wakho kungadingeka ukuthi anciphise umthamo weminye imithi yakho yesifo sikashukela. Khuluma nodokotela wakho ngalokhu.
3. I-Diabetic Ketoacidosis (DKA)
Lesi yisimo esibi kodwa esingavamile . Uma umzimba ungakwazi ukusebenzisa ushukela ukuze uthole amandla, ushisa amafutha ukuze uthole amandla. Phakathi nale nqubo, kukhiqizwa amakhemikhali abizwa ngokuthi ama-ketone. Lawa ayanqwabelana egazini, okwenza igazi libe ne-asidi, okubizwa ngokuthi i-DKA.
- Izimpawu: Ukoma ngokweqile, ukuchama njalo, izinhlungu zesisu, isicanucanu, ukuhlanza, ubunzima bokuphefumula, kanye nephunga elimnandi lokuphefumula.
- Okufanele ukwenze: Lesi yisimo esiphuthumayo sezokwelapha esingasongela impilo. Uma uhlangabezana nesinye noma ngaphezulu salezi zimpawu, kufanele uye eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela esiseduze ngokushesha.
Ngiyithola kanjani iFarxiga?
I-Farxiga akuyona imithi ongayithenga ekhemisi kuphela. Idinga incwadi kadokotela.
Umhlinzeki wakho wokunakekelwa okuyinhloko noma udokotela we-endocrinologist uzohlola impilo yakho futhi anqume ukuthi lo muthi ukulungele yini. Ungalokothi usebenzise lo muthi noma ushintshe umthamo onqunyiwe ngaphandle kokubonisana nodokotela.
Umlayezo Wokuya Nawe Ekhaya
- I-Farxiga (i-dapagliflozin) umuthi wesifo sikashukela sohlobo 2. Isiza ukulawula amazinga kashukela egazini ngokukhipha ushukela omningi emzimbeni ngomchamo.
- Ngaphezu kokulawula ushukela, kusiza futhi ekunciphiseni isisindo somzimba kanye nomfutho wegazi kancane, kunciphise ingozi yesifo senhliziyo, futhi kuvikele nezinso.
- Ukutheleleka kwemvubelo endaweni yesitho sangasese kuyimiphumela emibi evamile. Kubalulekile ukugcina inhlanzeko.
- Kukhona ingozi yokwehla kwe-hypoglycemia uma kuthathwa neminye imithi yesifo sikashukela njenge-insulin. Yazisa udokotela wakho ngalokhu.
- Qaphela izimpawu zesimo esibi esibizwa ngokuthi i-DKA. Uma ungabaza, hamba uye eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela ngokushesha.
- Lomuthi kufanele usetshenziswe kuphela ngokunconywa ngudokotela .
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