Kungenzeka ukuthi ukhathazeke kancane lapho ubona inani eliphezulu elinezinhlamvu ezintathu ze-GGT embikweni wakho wegazi. Ungase uzibuze, "Kuyini lokhu ku-GGT? Kungani kuphezulu kangaka?" Ungakhathazeki. Namuhla, sizoxoxa ngokuthi kuyini lokhu ku-GGT, ukuthi kungani kwenziwa lokhu kuhlolwa, nokuthi kusho ukuthini ngempela ukuthi inani eliphakeme.
Kuyini i-GGT?
Kalula nje, i-GGT, emele i-Gamma-Glutamyl Transferase, uhlobo lwe-enzyme emzimbeni wethu. I-enzyme yinto esiza ngezinqubo zamakhemikhali emzimbeni wethu. Le enzyme ye-GGT itholakala kakhulu esibindini sethu. Kodwa-ke, ingatholakala futhi ngamanani amancane kwezinye izingxenye zomzimba ngaphandle kwesibindi.
Umsebenzi wayo oyinhloko ukuvikela amangqamuzana emzimbeni wethu ekulimaleni. Cabanga nge-GGT njengabaqaphi abancane abavikela amangqamuzana ethu. Lapho amangqamuzana eqala ukonakala ndawana thile, laba baqaphi beza begijima ukuze bawavikele. Ngakho-ke, ukwanda kwezinga le-GGT egazini kusho ukuthi kukhona umonakalo ndawana thile emzimbeni, futhi i-enzyme ye-GGT isebenza kanzima kakhulu ukulwa nawo.
Kuyini ukuhlolwa kwegazi kwe-GGT?
Lokhu ukuhlolwa okuvamile kakhulu okuthatha isampula encane yegazi engalweni yakho. Udokotela wakho uzoyala lokhu kuhlolwa ukuze ahlole umonakalo wesibindi noma uma esola ukuthi kukhona ukuvaleka kwemisele yakho ye-bile . Lokhu kuhlolwa kulinganisa inani le-enzyme ye-GGT egazini lakho.
Amazinga aphezulu e-GGT angabonisa izimo eziningana zempilo ezithinta isibindi, inhliziyo, noma ezinye izitho zomzimba. Ukusetshenziswa kotshwala kanye nemithi ethile nakho kungabangela ukwenyuka kwamazinga e-GGT.
Kodwa into ebaluleke kakhulu ukuthi awukwazi ukuxilonga noma yisiphi isifo ngokubheka inani lombiko we-GGT kuphela. Odokotela bahlala besebenzisa lolu vivinyo lwe-GGT kanye nezinye izivivinyo eziningana ezihlola ukusebenza kwesibindi.
Lolu vivinyo lwe-GGT lubizwa nangamanye amagama amaningana:
- I-Gamma-glutamyl transpeptidase
- I-GGTP
- I-Gamma-GT
- I-GTP
Kungani udokotela angakutshela ukuthi wenze ukuhlolwa kwe-GGT?
Kungase kube nezizathu eziningana eziyinhloko zokuthi kungani udokotela wakho engase acele lolu vivinyo.
Uma unezimpawu zesibindi
Uma ubhekene nezimpawu zesifo sesibindi, udokotela wakho uzokutusa nakanjani lokhu kuhlolwa.
- Ukuphuzi kwesikhumba (i-jaundice)
- Ubuhlungu ohlangothini oluphezulu kwesokudla lwesisu
- Isicanucanu nokuhlanza
- Ukuzizwa ukhathele kakhulu
- Isifiso sokudla
Ezimweni ezinjalo, akugcini nje ngokuhlolwa kwe-GGT, kodwa nezinye izivivinyo eziningana ezilinganisa ukusebenza kwesibindi. Lezi yizivivinyo ze-`ALT (Alanine Transaminase)`, `AST (Aspartate Aminotransferase)`, `ALP (Alkaline Phosphatase)` kanye ne-`Bilirubin`. Kuphela lapho yonke le mibiko ihlangana khona lapho isithombe esiphelele singakheka khona.
Uma inani lakho le-ALP liphezulu
Cabanga ukuthi inani le-`ALP (Alkaline Phosphatase)` kuphela embikweni wakho wegazi liphakanyisiwe. Kungaba nezizathu ezimbili zokuthi inani le-ALP likhuphuke. Esinye inkinga ngesibindi noma imisele ye-bile. Esinye inkinga ngamathambo (amathambo).
Manje udokotela ufuna ukwazi ukuthi imbangela isibindi noma amathambo. Yilapho ukuhlolwa kwe-GGT kusiza khona kakhulu.
- Uma amazinga akho e-ALP kanye ne-GGT ephakanyisiwe , imbangela kungenzeka ukuthi iyinkinga yesibindi noma ye-bile duct.
- Uma izinga lakho le-ALP liphakeme kuphela futhi izinga lakho le-GGT lijwayelekile , imbangela kungenzeka ukuthi iyinkinga ehlobene namathambo.
Uyaqonda ukuthi lolu vivinyo lubaluleke kangakanani?
Uma kukhona okusolakala ngokusetshenziswa kotshwala
Ukuhlolwa kwe-GGT kusetshenziselwa ukuhlonza abantu abaphuza kakhulu nokuqapha isimo sabo ngesikhathi sokwelashwa. Lapho ukuphuza utshwala kulimaza isibindi (i-alcoholic hepatitis), inani le-GGT likhuphuka kakhulu.
Ingabe ngidinga ukulungiselela ngaphambi kokuhlolwa kwe-GGT?
Yebo, kudingeka ukulungiselela okuncane ngaphambi kokwenza lolu vivinyo.
- Tshela udokotela wakho ngemithi oyithathayo: Eminye imithi oyithathayo ingathinta amazinga akho e-GGT. Ngakho-ke, tshela udokotela wakho ngayo yonke imithi oyithathayo, okuhlanganisa amavithamini kanye nemithi yamakhambi. Ungalokothi uyeke ukuthatha noma yimuphi umuthi ngaphandle kokuba udokotela wakho ekutshele ukuthi wenze kanjalo.
- Gwema utshwala: Ungaphuzi noma yiluphi uhlobo lotshwala okungenani amahora angama-24 ngaphambi kokuhlolwa. Ngisho notshwala obuncane bungakhuphula amazinga akho e-GGT, okungenza umbiko ungabi neqiniso.
Kwenzekani ngesikhathi sokuhlolwa?
Lena inqubo elula kakhulu.
1. Uzohlaliswa esihlalweni, futhi umhlengikazi noma uchwepheshe wezokwelapha uzokhetha umthambo omuhle engalweni yakho (ngokuvamile ngaphakathi kwendololwane yakho).
2. Hlanza indawo nge-swab yekotini.
3. Bese kufakwa inaliti encane emthanjeni bese kukhishwa igazi elithile lingene epayipini. Ngalesi sikhathi, uzozwa ukuhlaba okuncane, njengokulunywa yintuthwane.
4. Ngemva kokukhishwa kwegazi, inaliti iyasuswa, kufakwa ucezu lwekotini endaweni bese lucindezelwa phansi. Bese kufakwa iplasta encane.
Lonke lolu hlelo luthatha imizuzu engaphansi kwemihlanu.
Kufanele libe yini inani elijwayelekile lombiko we-GGT?
Ngokuvamile, inani le-GGT kufanele libe ngaphansi kuka-50 U/L (amayunithi ngelitha). Kodwa-ke, lokhu kungahluka kancane kusuka elabhorethri kuya kwelebhu. Ngakho-ke, kungcono ukuqhathanisa inani lakho nenani elishiwo embikweni wakho njenge-'Normal Range' noma 'Reference Range'.
Futhi, amazinga e-GGT kwabesilisa avame ukuba phezulu kancane kunawabesifazane. Lawa manani angashintsha futhi ngokweminyaka.
Kusho ukuthini ukuthi izinga le-GGT liphezulu? Ingabe kufanele ngikhathazeke?
Okokuqala, ungesabi uma ubona izinga le-GGT eliphezulu. Izinga le-GGT eliphakeme limane nje liwuphawu lokuthi ungase ube nesimo noma isifo esilimaza isibindi sakho. Akusho ukuthi unesifo esithile.
Ithebula elingezansi libala izizathu eziningana zokuthi kungani amazinga e-GGT engase akhuphuke.
| Izimbangela ezingaba khona | Incazelo elula |
|---|---|
| Izimbangela Ezihlobene Nesibindi | |
| I-Hepatitis | Ukuvuvukala kwesibindi ngenxa yokutheleleka ngamagciwane noma utshwala. |
| I-Cirrhosis | Ukusha kwesibindi ngenxa yomonakalo wesikhathi eside. |
| I-Cholestasis | Ukuvaleka kokugeleza kwenyongo esibindini. |
| Isifo sesibindi esibangelwa utshwala | Ukulimala kwesibindi ngenxa yokuphuza utshwala ngokweqile. |
| Isifo Sesibindi Esinamafutha | Ukufakwa kwamafutha emangqamuzaneni esibindi. |
| Ukuncipha kokunikezwa kwegazi esibindini (i-Liver Ischemia) | Ukuntuleka kwegazi eliya ezicutshini zesibindi. |
| Izimila zesibindi noma umdlavuza | Ukukhula okungavamile kwamangqamuzana esibindini. |
| Ezinye Izimbangela | |
| Ukulutheka kotshwala | Ukusetshenziswa kotshwala obuningi isikhathi eside. |
| I-pancreatitis noma umdlavuza | Ukuvuvukala noma umdlavuza we-pancreas. |
| Isifo sikashukela | Ukungakwazi ukulawula amazinga kashukela egazini. |
| Ukwehluleka kwenhliziyo okubangelwa ukuminyana | Inhliziyo ayikwazi ukupompa igazi elanele emzimbeni. |
| Eminye imithi | Isibonelo: Izidakamizwa ezifana ne-`Phenobarbital`, `Phenytoin`, `Warfarin`. |
| Ukubhema | Ukubhema nakho kungabangela amazinga aphezulu e-GGT. |
Kodwa khumbula futhi, ukuthi i-GGT yakho iphakeme akusho ukuthi unalesi sifo. Udokotela wakho uzokwenza isiphetho ngokusekelwe kulo mbiko, kanye nokunye ukuhlolwa kwegazi, izimpawu zakho, kanye nomlando wakho wezempilo ophelele.
Kufanele ngikhulume nini nodokotela?
Uma unemibuzo mayelana nokuthi kungani ucelwe ukuthi ubhale ukuhlolwa kwe-GGT noma ukuthi umbiko wakho usho ukuthini, qiniseka ukuthi ubuza udokotela wakho.
Kuvamile ukusesha i-inthanethi uma ubona ushintsho embikweni. Kodwa njengoba ukuhlolwa okufana ne-GGT kuphela kungakwazi ukuthola isifo esithile, ukusesha okunjalo kuzobangela ukwesaba okungadingekile.
Udokotela wakho kuphela ongachaza kangcono incazelo yangempela yamanani asembikweni wakho nokuthi athinta kanjani impilo yakho. Uzokweluleka ngokusekelwe esimweni sakho sonke.
Umlayezo Wokuya Nawe Ekhaya
- I-GGT iyi-enzyme etholakala kakhulu esibindini. Iyahlolwa uma kusolwa ukuthi kukhona umonakalo wesibindi noma ukuvaleka kwe-bile duct.
- Ungesabi uma ubona izinga le-GGT liphakeme. Kumane kuyisibonakaliso sesifo, hhayi ukuxilongwa okuqondile.
- Odokotela bahlala beqhathanisa umbiko we-GGT nezinye izivivinyo zesibindi ezifana ne-ALT, AST, kanye ne-ALP.
- Ukusebenzisa utshwala, ukubhema, kanye neminye imithi nakho kungakhuphula amazinga e-GGT. Ungaphuzi utshwala ngaphambi kokuhlolwa.
- Uma unemibuzo noma ukukhathazeka mayelana nombiko wakho, khuluma nodokotela wakho. Yilapho uzothola khona ulwazi olunembile kanye nesiqondiso.
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