Izinto okudingeka uzazi ngeSifo Sokukhulelwa Esibizwa Nge-Gestational Trophoblastic Disease (GTD)!

Kungenzeka ukuthi awukaze uzwe ngegama elithi Gestational Trophoblastic Disease (GTD). Kodwa yisimo esingase senzeke ngezinye izikhathi ngesikhathi sokukhulelwa. Kalula nje, uhlobo lwesimila esikhula esibelethweni sakho, indawo lapho umntwana wakho ekhula khona, futhi esihlobene nokukhulelwa. Ingabe singaxoxa ngalokhu ngemininingwane ethe xaxa?

Lezi zimila ziqala ukukhula kusuka kumaseli abizwa ngokuthi ama-trophoblast . Lawa maseli ngokuvamile yiwo akhula abe yi -placenta ngesikhathi sokukhulelwa. Uyazi, i-placenta yingxenye ebaluleke kakhulu exhumanisa ingane nesibeletho sakho, inikeze umoya-mpilo kanye nezakhamzimba enganeni engaphakathi kwesibeletho sakho.

Kodwa-ke, kulesi simo 'se-GTD', esikhundleni sokukhula sibe yi-placenta enempilo, lawo maseli e-trophoblast (okungukuthi, amaseli afana ne-placenta) akhula ngendlela engavamile.

Ngokuvamile, i-GTD yenzeka ekuqaleni kokukhulelwa, ngemva kokuba isidoda sivundise iqanda. Siphinde sikubize lokhu ngokuthi ukukhulelwa kwe-molar . Kodwa noma lokhu kubizwa ngokuthi ukukhulelwa, lawa maseli awakhuli abe umbungu okhula ube ingane. Esikhathini esiningi, lezi yizimo ezingezona ezomdlavuza (ezingemnandi). Kodwa-ke, ezinye zazo zingaba umdlavuza futhi zisakazekele ezicutshini nasezithweni zomzimba eziseduze. Into ebalulekile ukuthi i-GTD iyisimo esingelapheka. Iningi labantu lingaqhubeka nokukhulelwa okunempilo ngemva kwalesi simo.

Yiziphi izimo ezingaba khona lapho i-GTD ingenzeka khona?

Sivame ukuthi i-GTD yenzeka ekuqaleni kokukhulelwa. Kodwa-ke, lesi simo singavela nangezinye izikhathi:

• Kungaba ngemva kokukhipha isisu noma ngemva kokukhipha isisu.
• Ngemva kokukhulelwa kwe-tubal. Okusho ukuthi, lapho iqanda elivundisiwe lingena epayipini le-fallopian esikhundleni sesibeletho.
• Ngisho nangemva kokukhulelwa okuvamile, kungenzeka kube yinto engavamile.

Yiziphi izinhlobo ze-GTD? Ake sibone?

Kunezinhlobo ezahlukene ze-`GTD`. Izimpawu nazo ziyahlukahluka kuye ngohlobo.

Ukukhulelwa kwe-Hydatidiform mole noma i-molar

Lolu uhlobo oluvame kakhulu lwe-GTD. Luvame ukubizwa nangokuthi ukukhulelwa kwe-molar . Lokhu kwenzeka lapho, esikhundleni se-placenta noma i-embryo, kuvela i-cyst efana namagilebhisi esibelethweni sakho. Ungase uzizwe ukhulelwe, futhi ukuhlolwa kokukhulelwa kungaba yiqiniso. Kodwa-ke, i-ultrasound scan ngeke ibonise ingane ekhulayo. Ukuhlolwa kokukhulelwa kuba yiqiniso ngenxa ye-hormone yokukhulelwa ekhiqizwa yi-placenta. Kunezinhlobo ezimbili zama-hydatidiform moles: ama-complete kanye nama-partial hydatidiform moles. Ukukhulelwa okuningi kwe-molar akusona umdlavuza.

Uphawu oluvame kakhulu lokukhulelwa kwe-molar ukuphuma kwegazi okungajwayelekile esithweni sangasese sowesifazane ekuqaleni kokukhulelwa. Lokhu kuphuma kwegazi kungaba bomvu noma kube nsundu ngamanzi. Ngezinye izikhathi kungahambisana nobuhlungu besisu.

Ukukhulelwa kwe-molar okuqhubekayo/okungenayo

Lokhu kubhekwa njengokukhulelwa kwe-molar. Lolu hlobo lwe-molar olungenayo lungakhula lube yimisipha yesibeletho. Ngokungafani nezinye izinhlobo zokukhulelwa kwe-molar, la ma-molar angenayo ngokuvamile anomdlavuza. Uma engelashwa, la maseli omdlavuza avame ukuhlala emisipheni yesibeletho, kodwa ngezinye izikhathi angasakazekela kwezinye izingxenye zomzimba noma izicubu.

I-Choriocarcinoma

I-Choriocarcinoma uhlobo lwe-GTD olukhula ngokushesha futhi olunomdlavuza. Luqala olwelwesini lwesibeletho sakho futhi lungasakazekela kwezinye izitho zomzimba, njengesitho sakho sangasese sowesifazane, amaphaphu, izinso, isibindi kanye nobuchopho. Lesi futhi yisimo esingavamile kakhulu, kodwa kungenzeka kakhulu ukuthi sikhule kubantu abake baba nokukhulelwa kwe-molar ngaphambilini.

Abanye abantu bangase bangabi nazimpawu nhlobo. Kodwa kulabo abanezimpawu, uphawu oluvame kakhulu ukopha okungajwayelekile kwesitho sangasese sowesifazane ngemva kokuphuphuma kwesisu, ukukhipha isisu, noma ukukhulelwa kwe-molar. Abanye abantu bangase babe nobuhlungu besisu, igazi emchameni, noma igazi esitulweni.

Isimila se-trophoblastic esitholakala endaweni ye-placental (PSTT)

I-Placental site trophoblastic tumor (PSTT) uhlobo olungavamile kakhulu lwe-GTD. Lukhula lapho i-placenta inamathela khona esibelethweni. I-PSTT ikhula kancane kakhulu. Ngakho-ke, kungathatha iminyaka eminingi ngemva kokukhulelwa ukuthi izimpawu zivele. I-PSTT ingasakazekela emisipheni yesibeletho, emithanjeni yegazi, emaphashini, e-pelvis, kanye nasema-lymph node, ngakho-ke ukwelashwa okusebenzayo kuyadingeka.

Isimila se-trophoblastic se-Epithelioid (ETT)

Lolu futhi uhlobo olungavamile kakhulu lwe-'GTD' olunomdlavuza. Njenge-'PSTT', lungasakazekela emaphashini. I-'ETT' ingakhula futhi eminyakeni eminingi ngemva kokukhulelwa.

Sivame kangakanani lesi simo?

E-United States, kuthiwa i-GTD yenzeka cishe koyedwa kwabayi-1,000 abakhulelwe. Uhlobo oluvame kakhulu lwe-GTD yi-hydatidiform moles, esixoxe ngayo ngaphambili. Izimo ze-GTD ezingathi sína kakhulu, njenge-choriocarcinoma, zenzeka koyedwa kwabayi-20,000 abakhulelwe. Lokhu kusho ukuthi azivamile kakhulu.

Ingabe i-GTD ingaba yingozi?

Amacala amaningi e-'GTD', ikakhulukazi uma etholakala kusenesikhathi, angelashwa futhi alapheke ngokuphelele.Kodwa-ke, ezimweni ezithuthukile, i-GTD ingaba yingozi. Yingakho ukuxilongwa kusenesikhathi kanye nokwelashwa kubalulekile.

Ziyini izimpawu ze-GTD?

Abanye abantu abane-GTD bangase bangabi nazo nhlobo izimpawu. Abanye bangase babe nezimpawu ezifana nezokukhulelwa noma ezinye izifo/izimo. Uma unezinye zalezi zimpawu, qiniseka ukuthi ubona udokotela wakho:

• Uma uphuma igazi ngendlela engajwayelekile esithweni sangasese sowesifazane, noma ukopha okungahlobene nokuya kwakho esikhathini kwanyanga zonke.
• Uma isibeletho sakho sizwakala sikhulu kunalokho obekulindelwe ngokukhulelwa kwakho.
• Uma unezinhlungu esiswini noma endaweni ye-pelvic.
• Uma isicanucanu nokuhlanza kwenzeka ngaphambi kwesikhathi esilindelekile ngesikhathi sokukhulelwa.
• Uma unomfutho wegazi ophezulu ekuqaleni kokukhulelwa, noma uma izitho zakho zivuvukele.
• Uma uqhubeka nokopha esithweni sakho sangasese, kungakhathaliseki ukuthi ngemva kokubeletha noma ngemva kokuphuphuma kwesisu.

Isifo se-Gestational Trophoblastic ngezinye izikhathi singabangela i-thyroid esebenza ngokweqile . Uma lokhu kwenzeka, ungase ube nezimpawu ezifana nalezi:

• Isilinganiso senhliziyo siyanda.
• Ukuthuthumela.
• Ukwehlisa isisindo.
• Ukujuluka.

Yiziphi izimbangela zokukhulelwa kwe-molar?

Kalula nje, ekukhulelweni okuvamile, lapho iqanda livundiswa yisidoda, liqukethe lonke ulwazi oludingekayo ukwakha umbungu kanye ne-placenta. Sibiza leli qoqo lokuqala lamaseli ngokuthi i-blastocyst . Lombungu yilokho okuthuthuka kamuva ube umbungu. Ungqimba lweseli le-trophoblast luba yingxenye ye-placenta futhi lusize i-blastocyst ukuthi inamathele odongeni lwesibeletho.

Kodwa-ke, ekukhulelweni kwe-molar, umbungu awukhuli kahle ngoba ukukhulelwa akuzange kwenzeke. Esikhundleni salokho, amangqamuzana e-trophoblast akhula abe amathumba esikhundleni se-placenta enempilo. Lena yimbangela eyinhloko.

Ungayibona kanjani i-GTD?

Udokotela wakho uzoxilonga i-GTD ngokuthatha umlando wakho wezokwelapha ophelele, enze ukuhlolwa ngokomzimba, futhi enze ezinye izivivinyo ukuze abheke ngaphakathi kwesibeletho sakho. I-GTD ingaxilonga ngokuthi:

• Ukuhlolwa kwe-pelvic: Udokotela ufaka iminwe egqoke amagilavu ​​​​esithweni sangasese sowesifazane bese ehlola izimpawu zesifo, njengezigaxa noma ubuningi, noma usayizi wesibeletho.
• Ukuskena nge-Ultrasound: Lokhu kusebenzisa amaza omsindo ukuthatha izithombe zezitho zakho zangaphakathi. Uma udokotela wakho esola ukuthi i-GTD iyasebenza, i-ultrasound ye-transvaginal izothatha izithombe ze-pelvis yakho kanye nesibeletho.
• Ukuhlolwa kwegazi:Ukuze kusizwe ekuxilongweni kwe-GTD, kwenziwa ukuhlolwa kwegazi ukuze kulinganiswe amazinga ezinto ezithile emzimbeni wakho. Isibonelo, owesifazane okhulelwe one-GTD angaba namazinga aphezulu kakhulu e-hormone ebizwa ngokuthi i-human chorionic gonadotropin (hCG) kunowesifazane okhulelwe ongenayo i-GTD. Uma umdlavuza ususakazekele kwezinye izicubu noma izitho zomzimba, umzimba wakho ungase ukhiqize izinto ezithile eziningi noma ezimbalwa ukuze ubonise lesi sifo.

Ukunquma izigaba zesifo

Ngemva kokuxilongwa ukuthi une-GTD, udokotela wakho angase acele ukuhlolwa okwengeziwe ukuze abone ukuthi umdlavuza ususakazeke kwezinye izingxenye zomzimba wakho. Ukulinganisa isigaba sesifo kuyinqubo yokuthola ukuthi umdlavuza ususakazeke kangakanani nokuthi ungakanani. Le miphumela isiza odokotela ukuthi banqume ukuthi yisiphi isigaba somdlavuza onaso.

Izigaba zomdlavuza zibhalwa ngezinombolo zesiRoma njengo-I, II, III, kanye no-IV. Uma inani liphezulu, kulapho umdlavuza usabalala khona kakhulu.

Ukuhlolwa okusetshenziselwa ukuthola izigaba ze-`GTD` kungaba:

• I-CT scan (i-computed tomography - i-CT scan): Lokhu kusebenzisa uchungechunge lwe-X-ray kanye nekhompyutha ukudala isithombe sezicubu namathambo esinezinhlangothi ezintathu (3D).
• Ukuskena kwe-MRI (i-Magnetic resonance imaging - i-MRI): Lokhu kusebenzisa i-magnet namagagasi omsakazo ukwenza izithombe ezinemininingwane yomzimba wakho. Udokotela angase afake into ebizwa ngokuthi i-gadolinium emithanjeni yakho, ngoba le nto yenza amangqamuzana omdlavuza abonakale kakhulu esithombeni.
• I-X-ray yesifuba: Lokhu kusebenzisa umsebe wemisebe ogxile ekuhloleni amaphaphu akho, ezinye izitho ezingaphakathi kwesifuba sakho, kanye namathambo.

Iphathwa kanjani i-GTD?

Izindlela zokwelapha zeSifo Sokukhulelwa Se-Trophoblastic ziyahlukahluka. Kunezici eziningana ezisithintayo. Njenge:

• Uhlobo lwe-`GTD`, ubukhulu besimila, kanye nendawo yaso.
• Kungakhathaliseki ukuthi isimila sisakazeke, noma ukuthi sisezingeni lini.
• Kungakhathaliseki ukuthi isimila senzeke ngesikhathi sokukhulelwa, noma ngemva kokukhipha isisu noma ukubeletha.
• Impilo yakho iyonke.
• Umlando wakho wezokwelapha nokuthi ngabe wake welashwa yini nge-GTD ngaphambilini.
• Izinhlelo zakho zokuba nezingane.

Udokotela wakho uzonquma ukwelashwa okufanele kakhulu kwesimo sakho. Nazi ezinye izindlela zokwelapha ze-GTD:

• Ukuhlinzwa: Ukuhlinzwa kokususa izicubu namaseli angajwayelekile esibelethweni. Ukuhlinzwa okuvamile kwe-GTD ukunwebeka kanye nokususwa kwezicubu (D&C) . Lokhu kuhilela ukuvula umlomo wesibeletho kanye nokuhlanza isibeletho.
• Ukwelashwa ngamakhemikhali: Ukwelashwa ngamakhemikhali, noma "i-chemo," ukusetshenziswa kwemithi ukubhubhisa amangqamuzana omdlavuza.
• Ukwelashwa ngemisebe:Ukwelashwa ngemisebe kusebenzisa imisebe yamandla enamandla ukubulala amangqamuzana omdlavuza nokunciphisa izimila.
• Ukususwa kwesibeletho: Ukususwa kwesibeletho inqubo yokuhlinzwa esusa isibeletho sakho. Ngezinye izikhathi, ezinye izitho zomzimba, njengemibhobho ye-fallopian nama-ovari, nazo zingasuswa.

Wena nodokotela wakho kufanele nixoxe ngemithi yokwelapha etholakalayo, kanye nezingozi nemiphumela emibi yaleyo mithi.

Ingabe i-GTD ingaphinde ivele?

Yebo, iSifo Sokukhulelwa Se-Trophoblastic singaphinde sibuye. Kuye ngohlobo lwe-GTD owawunayo ekuqaleni nokuthi wasabela kanjani ekwelashweni, kunengozi encane yokuphinda ubuye. Yingakho odokotela bezoqhubeka nokukuqapha ngemva kokwelashwa.

Ngingaba nomntwana ngemva kwe-GTD?

Yebo, impela! Iningi labantu abanomlando we-'GTD' lingaqhubeka nokukhulelwa okuvamile nokunempilo. Kodwa-ke, kuye ngomlando wakho, udokotela wakho angase ancome ukuhlolwa okwengeziwe ekukhulelweni okulandelayo.

Ingabe i-GTD ingavinjelwa?

Ayikho indlela yokuvimbela ngempela iSifo Sokukhulelwa Esibangelwa I-Trophoblastic. Lokhu kuyinto esingenakukwazi ukuyilawula.

Izici zengozi zokuthuthukisa i-GTD

Nakuba iSifo Sokukhulelwa Esibizwa ngokuthi i-Gestational Trophoblastic Disease siyisimo esingavamile, kunezici ezithile ongeke ukwazi ukuzilawula ezingandisa ingozi yakho yokuba naso. Lezi zinto zifaka:

• Ubudala bakho. Abantu abangaphezu kweminyaka engama-35 ubudala kanye nalabo abangaphansi kweminyaka engama-20 ubudala basengozini enkulu kancane yokuthola i-GTD.
• Uma uke wakhulelwa umbungu ngaphambili.
• Uma othile emndenini eke waba nokukhulelwa kwe-molar, lokho kusho ukuthi umlando womndeni uhilelekile.

Ngakho-ke, yiziphi izinto okudingeka sizikhumbule kukho konke lokhu?

Uma uthola ukuthi unesifo sokukhulelwa i-Gestational Trophoblastic Disease (GTD), kuvamile ukuzizwa wesaba, ukhathazekile futhi udabuke. Kungaba nzima futhi ukubhekana nokulahlekelwa ukukhulelwa kwakho kanye nokuthola ukuxilongwa okuyinkimbinkimbi kangaka ngesikhathi esisodwa.

Kodwa khumbula, udokotela wakho uzokwenza izivivinyo ezahlukene, aqonde isimo sakho esiqondile, futhi anqume ukwelashwa okufanele kakhulu. Into ebalulekile ukuthi ezimweni eziningi, i-'GTD' iyisimo esingelapheka. Amathuba akho okukhulelwa futhi (uma ufuna) nawo mahle kakhulu.

Funa ukwesekwa emndenini wakho, kubangani, nakodokotela phakathi nalesi sikhathi esinzima. Futhi ungazigodli lutho, futhi ungesabi ukubuza imibuzo. Awuwedwa, sonke sinawe.

Isifo se - trophoblastic sokukhulelwa, i-GTD, ukukhulelwa kwe-molar, umdlavuza wesibeletho, i-placenta, i-choriocarcinoma, izinkinga zokukhulelwa