Uyazazi yini izimila ezinkulu (GCT)? Ake sixoxe ngazo!

Wake wazizwa ubuhlungu obungajabulisi, ukuvuvukala okuncane, noma iqhubu esandleni sakho, ikakhulukazi edolweni lakho, esinqeni, ehlombe, noma esihlakaleni? Uma kunjalo, kuwumqondo omuhle ukukhathazeka kancane. Ngoba kungaba uphawu lwesimo esizokhuluma ngaso namuhla esibizwa ngokuthi 'i-Giant Cell Tumor (GCT)'. Ungakhathazeki, sizoxoxa ngalokhu ngokuningiliziwe.

Iyini ngempela i-Giant Cell Tumor (GCT)?

Kalula nje, i-"Giant Cell Tumor (GCT)" iyisimila esingeyona umdlavuza (futhi esivame ukuba yingozi) . Ngokuvamile sakha emaphethelweni amathambo amade emzimbeni wakho. Ngokukhethekile, sivame ukutholakala phansi kwethambo lakho lethanga elithi "femur" noma phezulu kwethambo lakho lesifuba elithi "tibia", elizungeze idolo . Kodwa-ke, singakha nasezindaweni ezifana nesinqe, ihlombe, isihlakala, kanye nethambo lomsila. Lokhu kubizwa nangokuthi "ama-Osteoclastomas".

Lesi simo esibizwa ngokuthi `(GCT)` empeleni asivamile kakhulu . Sivela cishe kubantu oyedwa kuya kwababili kwabayikhulu ezinkulungwaneni. Kodwa-ke, phakathi kwezimila ezingezona umdlavuza eziqala emathanjeni, `(GCT)` ziphakathi kuka-15% no-21% wazo zonke izimo.

Ngezinye izikhathi la mathumba amakhulu amangqamuzana awakhuli emathanjeni, kodwa akhula ezicutshini ezithambile ezizungeze amalunga. Bese kuthiwa amathumba amakhulu amangqamuzana e-Tenosynovial.

Into ebalulekile ukuthi nakuba lawa ma-"Giant Cell Tumors" angewona umdlavuza, angakhula ngokushesha futhi alimaze izicubu ezinempilo ezizungezile . Futhi, anethuba elikhulu lokuthi "aphinde avele" ngisho nangemva kokwelashwa. Yingakho kubalulekile ukubona udokotela ngokushesha okukhulu uma ubona noma yiziphi izimpawu zesimila esinjengalesi.

Ziyini izimpawu zalokhu? Bheka ukuthi nawe unazo lezi...

Uphawu oluyinhloko noluvame kakhulu lwesimila esikhulu seseli (i-GCT) ubuhlungu . Nakuba ubuhlungu bungase bube buthakathaka ekuqaleni, buyanda njengoba isimila sikhula. Cabanga nje, uvuka ekuseni ngolunye usuku uzizwe ubuhlungu obuncane eduze kwedolo lakho. Ekuqaleni, uyabushaya indiva. Kodwa ngemva kwesikhashana, ubuhlungu buyakhula, futhi uma ubuthinta, buzwakala sengathi yiqhubu elincane. Yilapho-ke usaba khona kancane, akunjalo?

Kunezinye izimpawu eziningana:

• Iqhubu noma ukuvuvukala okubonakalayo esandleni kubonakala kuleyo ndawo.
• Ukungakwazi ukuhambisa ilunga kahle lapho kukhona khona isimila kusho ukuthi ukunyakaza kwelunga kulinganiselwe.
• Ubuhlungu bamalunga , ikakhulukazi uma kususwa ilunga.
• Ukuvuvukala .
• Isimila singawenza buthaka amathambo futhi sibangele ukuqhekeka .

Uma unesinye noma ngaphezulu salezi zimpawu, sicela ufune iseluleko sezokwelapha.

Kungani kwenzeka into efana nale? Iyini imbangela?

Eqinisweni, abacwaningi bezokwelapha abakakazi kahle ukuthi yini ebangela izimila ezinkulu zamaseli. Kodwa-ke, abanye abantu abanalesi simo kutholakale ukuthi banezinguquko ezithile (ukuguqulwa kwezakhi zofuzo) ezizakhini zabo zofuzo. Kodwa-ke, okwamanje kukholelwa ukuthi lokhu akuyona into ezuzwe njengefa, noma into ebangelwa indawo ohlala kuyo noma indlela ophila ngayo .

Ingabe zikhona izinto eziyingozi?

Yebo, ngaphansi kwezimo ezithile amathuba okuthuthukisa le `(GCT)` anganda kancane:

• Uma unesifo esibizwa ngokuthi `(Hyperparathyroidism)` (lapho ukhiqiza khona i-parathyroid hormone eningi kakhulu), `(GCT)` ingakhula ezindaweni eziningana emzimbeni wakho.
• Akuvamile kakhulu ukuthi abantu abanesifo samathambo esibizwa ngokuthi "isifo sikaPaget sethambo" nabo bangahlakulela lezi zimila ezinkulu zamaseli.

Ingabe lokhu kungaba yingozi? Yiziphi izinkinga?

Nakuba lezi zimila zingewona umdlavuza, akuvamile, okungukuthi, akuvamile kakhulu, lezi zimila ezinkulu zamaseli zingasakazeka emaphashini . Kodwa-ke, akufani nokusakazeka komdlavuza, futhi noma ngabe usakazeka ngale ndlela, ngokuvamile awusongeli impilo.

Ngisho nakancane kakhulu, kubantu abangaba ngu-4% abane-GCT, la mathumba angaba umdlavuza (ayingozi) . Ngakho-ke, udokotela wakho uzoqapha isimo sakho njalo ukuze abone ukuthi kukhona yini izinguquko eziyingozi kulesi simila. Yingakho kubalulekile ukubona udokotela wakho njalo futhi uthole iseluleko.

Odokotela bakuthola kanjani lokhu?

Ukuqinisekisa ukuthi unesimila seseli elikhulu (i-GCT) , kwenziwa i-biopsy . Lokhu kuhilela ukuthatha isampula encane yezicubu ezivela kulesi simila bese uyihlola ngaphansi kwe-microscope. Lokhu kuhlolwa kwenziwa yisazi sezifo, udokotela ochwepheshe bezicubu. Uzohlola ukuthi amaseli "angamaseli amakhulu," noma anezici ze-GCT.

Ngaphezu kwalokho, ukuhlolwa kwezithombe okufana nalokhu kungenziwa ukuze kubhekwe isimila emzimbeni wakho:

• Ama-X-ray : Hlola isimo samathambo.
• I-CT scan : Bheka usayizi nesimo sesimila ngokuningiliziwe.
• I-MRI : Ihlola izicubu ezithambile, umongo wamathambo, njll.
• Ukuskena kwamathambo : Hlola izinkinga kwezinye izindawo emathanjeni.
• Ukuskena kwe-PET : Ukubona ukuthi kukhona yini izimpawu zokuthi isimila siphenduka umdlavuza.

Zonke lezi zivivinyo zenziwa ukuze kuqondwe kahle isimo sakho futhi kutholakale ukwelashwa okungcono kakhulu.

Kulungile, manje yiziphi izindlela zokwelapha lokhu?

Amathumba amakhulu amangqamuzana avame ukwelashwa ngokuhlinzwa . Udokotela ususa isimila ethanjeni (i-curettage). Ngemuva kwalokho, kufakwa i-bone graft endaweni engenalutho.Ithambo liqiniswa ngokuxhunyelelwa (ingxenye yethambo ethathwe kwenye indawo noma into yokwenziwa). Ngezinye izikhathi, uma isimila sikhulu kakhulu, lonke ithambo eliqukethe isimila kungadingeka lisuswe. Kuleso simo, ijoyinti lokwenziwa noma ithambo elithi "prosthesis" lingafakwa endaweni yalo.

Kodwa-ke, ezimweni lapho ukuhlinzwa kungenakukususa ngokuphelele isimila, noma uma ukuhlinzwa kuyingozi, kunezindlela zokwelapha ezingadingi ukuhlinzwa. Lokhu kufaka phakathi:

• I-Denosumab (i-Denosumab - i-Xgeva®) : Lolu uhlobo lomuthi olubizwa ngokuthi i-monoclonal antibody. Lunciphisa isimila futhi luqinise ithambo elizungezile.
• Ukufakwa kwegazi emzimbeni : Lokhu kuhilela ukuvimba imithambo yegazi ehambisa igazi esimila. Lokhu kuphuca isimila igazi futhi kubangele ukuthi sife kancane kancane.
• Ukwelashwa kokukhipha isisu : Lokhu kusebenzisa into efana namandla e-microwave ukubhubhisa isimila.
• Ukwelashwa ngemisebe : Lokhu kusebenzisa ama-X-ray anamandla aphezulu ukunciphisa isimila nokubhubhisa amaseli.

Udokotela wakho uzonquma ukuthi yikuphi ukwelashwa okungcono kakhulu kuwe.

Kuthatha isikhathi esingakanani ukululama ngemva kokwelashwa?

Isikhathi esithathayo ukuze ululame sincike ekwelashweni okutholile. Uma uhlinzwe, kuzodingeka ubophe amabhandeshi amasonto amaningana ngenkathi inxeba liphola. Kungase kudingeke futhi usebenzise izinduku zokusibekela phakathi naleso sikhathi. Uma unedivayisi yokufakelwa, kuzodingeka usebenze nodokotela wezokwelapha ngokomzimba ukuze ujwayele.

Udokotela wakho uzochaza konke lokhu kuwe, ngakho-ke akukho okufanele ukhathazeke ngakho.

Ayikho indlela yokuvimbela lokhu ukuthi kwenzeke? Iyini inzuzo yokwazi kusengaphambili?

Njengoba imbangela eqondile yama-giant cell tumors ingaziwa, okwamanje ayikho indlela yokuwavimbela ukuthi angakhuli . Kodwa-ke, into engcono kakhulu ongayenza ukufuna iseluleko sezokwelapha ngokushesha nje lapho ubona izimpawu . Uma ubona ubuhlungu, ukuvuvukala, noma iqhubu kwelinye lamathambo noma amalunga akho, ungakushayi indiva bese ubona udokotela ngokushesha. Uma ama-tumors afana ne-`(GCT)` etholakala kusenesikhathi, kulula ukuwaphatha futhi anezinkinga ezimbalwa.

Uma kungenzeka, kungcono ukubona udokotela ogxile kumdlavuza ohlobene namathambo, udokotela wezifo zamathambo .

Ngakho-ke uphila kanjani nalesi simo? Ingabe kufanele ubonane nodokotela njalo?

Amathumba amakhulu amangqamuzana awavamile ukuba yingozi empilweni. Kodwa-ke, angalimaza amathambo akho nezicubu ezizungezile, yingakho ukwelashwa kusenesikhathi kubalulekile.

Izindaba ezinhle ukuthi uma zonke izingxenye zesimila zisuswa ngokuhlinzwa, lesi simo singalapheka ngokuphelele. Kodwa-ke, i-GCT uhlobo lwesimila oluqinile futhi lungakhula futhi .

Ngemva kokwelashwa, udokotela wakho uzokubheka njalo ukuze athole ama-aphoyintimenti okulandelela . Lokhu kwenzelwa ukuhlola ukuthi isimila sesibuyile yini. Ngokuvamile, lezi zimila zibuya eminyakeni emibili kuya kwemihlanu yokuqala ngemva kokuhlinzwa. Kodwa-ke, kungadingeka ukuthi uhlolwe njalo impilo yakho yonke. Udokotela wakho uzokutshela ukuthi kufanele uze kangaki ukuze uthole lokhu kuhlolwa.

Kunini lapho udinga ukubonana nodokotela futhi?

Uma unezimpawu zokuthi isimila sakho esikhulu siyabuya, bona udokotela wakho ngokushesha. Qaphela noma yikuphi ubuhlungu obusha bethambo noma amalunga noma ukuvuvukala. Ngisho noma udokotela wakho ekubheka njalo, uma ubona noma yiziphi izinguquko, kungcono ukushayela udokotela wakho ucingo ngokushesha ngaphandle kokulinda i-aphoyintimenti yakho elandelayo.

Yini ongathanda ukuyibuza udokotela?

Uma ubona udokotela, kuwumqondo omuhle ukubuza le mibuzo:

• Ingabe lesi simila sinamandla kangakanani?
• Yiziphi izindlela zokwelapha enginazo?
• Yiziphi izinzuzo nezingozi ezihlobene nokwelashwa ngakunye kwalokhu?
• Lingakanani ithuba lokuthi lesi simila esikhulu seseli sizophinde sibuye ngemva kokwelashwa?
• Kukangaki lapho kuzodingeka ngize khona ukuze ngithole ama-aphoyintimenti okulandelela ?

Ukwazi izimpendulo zale mibuzo kuzokusiza ukuthi uqonde kangcono isimo futhi kwenze kube lula ukubhekana nokwelashwa.

Ngakho-ke, yiziphi izinto ezibaluleke kakhulu okudingeka sizikhumbule kule ndaba?

Ukuthi nje isimila esikhulu seseli (i-GCT) "singesihle" akusho ukuthi ngeke sibangele umonakalo. Uma singelashwa, lawa ma-GCT angabangela umonakalo omkhulu emathanjeni akho.

Into engcono kakhulu ukuthi ungaziqeda ngokuhlinzwa ukuze kususwe yonke iminonjana yesimila. Kodwa-ke, lezi `(GCT)` zilukhuni kancane futhi zingakhula futhi. Yingakho udokotela wakho ezokuqapha eduze ngemva kokwelashwa. Ukususa isimila sisesincane kungavimbela ukulimala kwamathambo isikhathi eside.

Ngakho-ke, uma unalezi zimpawu, ungangabazi ukubona udokotela bese uthola iseluleko. Ukwelashwa kusenesikhathi kuyindlela engcono kakhulu yokuphila impilo enempilo!

` I-Giant Cell Tumor, i-GCT, i-osteoclastoma, i-benign tumor, i-bone tumor, ubuhlungu bethambo, ukwelashwa kwe-tumor