Uma udokotela wakho ekutshela noma othandekayo wakho ukuthi une-cystic fibrosis (CF), cishe unemibuzo eminingi mayelana nemithi azoyinika. Njengoba kuyisimo esiyinkimbinkimbi, kubalulekile ukwazi ngokugcwele ngemithi azoyinika. Namuhla sizokhuluma ngomunye wemithi enjalo. Yiphilisi elihlanganisiwe elibizwa ngokuthi i-ORKAMBI, okuyinhlanganisela yemithi emibili ebizwa ngokuthi i-Lumacaftor kanye ne-Ivacaftor.
Luhlobo luni lomuthi? Yini ngempela le eyenzayo?
Kalula nje, i-cystic fibrosis (CF) yisimo esibangelwa ukukhubazeka kweprotheni emzimbeni wethu. Lokhu kubangela ukuthi uketshezi olusemaphashini nasezithweni zethu, ikakhulukazi ulwelwesi, lube lujiyile futhi lunamathele. Cabanga ngakho, ngokuvamile ulwelwesi olusemaphashini ethu lugeleza kancane, ngakho luphuma kalula. Kodwa ulwelwesi olukumuntu one-CF empeleni lujiyile, njengeglue. Lolwelwesi olujiyile lubhajwa emaphashini, okubangela ubunzima bokuphefumula, ukukhwehlela, kanye nokutheleleka njalo.
I-Lumacaftor; Lo muthi obizwa ngokuthi i-Ivacaftor usebenza ngokuya kuleyo phrotheni enephutha engikhulume ngayo bese uyilungisa ngezinga elithile. Kufana nokulungisa isango eliphukile. Lapho le phrotheni iqala ukusebenza kahle, indlela usawoti namanzi ahamba ngayo emangqamuzaneni omzimba iyalingana. Khona-ke lowo mucu ojiyile, onamathelayo uba mncane kancane futhi uqala ukuba lula ukuwususa emaphashini. Lokhu kungalawula izimpawu eziningi ze-CF.
Kodwa into eyodwa okufanele uyikhumbule ukuthi lokhu akulona ikhambi le-cystic fibrosis (CF). Kumane kuyindlela yokwelapha esiza ukulawula izimpawu nokwenza impilo ibe lula.
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuthatha umuthi
Ngaphambi kokuqala lo muthi, kubaluleke kakhulu ukwazisa udokotela wakho ngomlando wakho wezempilo ophelele. Ngoba ezinye izimo zidinga ukunakekelwa okukhethekile lapho usebenzisa lo muthi. Uma unezinye zezimo ezilandelayo, qiniseka ukuthi utshela udokotela wakho.
| Isimo sempilo noma ithuba | Kungani udinga ukutshela udokotela? |
|---|---|
| Isifo sesibindi | Lo muthi ungathinta isibindi. Uma usuvele unezinkinga zesibindi, umthamo wakho ungadinga ukulungiswa noma kungadingeka uhlolwe kaningi. |
| Isifo sezinso | Kubalulekile futhi ukukhathazeka ngomsebenzi wezinso. |
| Umfutho wegazi ophakeme | Lo muthi ungabangela ukuthi umfutho wegazi ukhuphuke kakhulu, ngakho-ke kubalulekile ukuqaphela lokho futhi. |
| Uma ukhulelwe noma uzama ukukhulelwa | Kufanele nakanjani ukhulume nodokotela wakho mayelana nokuphepha kwalomuthi ngesikhathi sokukhulelwa. |
| Uma umntwana enceliswa ibele | Xoxa nodokotela wakho ukuthi umuthi udlulela enganeni ngobisi lwebele kanye nemiphumela yawo. |
| Ukungezwani neminye imithi, ukudla, noma udayi | Lolu lwazi lubalulekile ukwazi ukuthi une-allergy kulo muthi noma kunoma yiziphi izithako zawo. |
Uyisebenzisa kanjani le mithi?
Lena yingxenye ebaluleke kakhulu. Uma ungawusebenzisi kahle lo muthi, imiphumela ingase inciphe.
- Yithathe kanye nokudla okunamafutha: Lona umthetho obaluleke kakhulu . Ukuze lo muthi umuncwe kahle ngumzimba, kufanele uthathwe kanye nokudla okunamafutha. Isibonelo, yithathe kanye nento efana namaqanda, ibhotela, ushizi, amakinati, i-avocado. Uma uwunika ingane encane, ungawunika kanye nobisi lwebele, ubisi oluyimpuphu noma imikhiqizo yobisi enamafutha agcwele njenge-yogurt, ushizi.
- Yithathe njengoba nje udokotela wakho ekuyalele: thatha umthamo ofanele, ngesikhathi esifanele. Qhubeka ukuyisebenzisa kuze kube yilapho udokotela wakho ekutshela ukuthi uyeke.
- Ungaphuzi ijusi likagrapefruit: Gwema ukuphuza ijusi likagrapefruit noma likagrapefruit ngenkathi uthatha lo muthi.
- Uma kunikezwa izingane: Lo muthi unganikezwa izingane ezingaphezu kweminyaka engu-6 ubudala. Kodwa-ke, udokotela wakho uzokunikeza imiyalelo ekhethekile ngalokhu.
Kuthiwani uma ngiphuza umuthi omningi kakhulu?
Uma ucabanga ukuthi uthathe umuthi ongaphezu komthamo onqunyiwe, shayela ngokushesha i-National Poisons Information Centre e-Colombo National Hospital, noma uye eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela esiseduze.
Kuthiwani uma ngikhohlwa umthamo?
Uma ukhohlwa ukuthatha umthamo, thatha ngokushesha nje lapho ukhumbula. Kodwa-ke, uma kungaphansi kwamahora ayisithupha ngaphambi komthamo wakho olandelayo, ungawuthathi umthamo ongawutholanga. Yeqa bese uthatha umthamo olandelayo ngesikhathi esihleliwe. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa.
Eminye imithi engase ihlangane nalo muthi
Lokhu kuyinto okufanele uyiqaphele kakhulu. I-ORKAMBI ingasebenzisana neminye imithi eminingi. Lokhu kusho ukuthi ukuyithatha neminye imithi kungashintsha imiphumela ye-ORKAMBI, kushintshe imiphumela yeminye imithi, noma kubangele imiphumela emibi kakhulu.
Ngakho-ke, kufanele utshele udokotela wakho ngayo yonke imithi oyithathayo (imithi yezinye izifo, amavithamini, imithi yamakhambi, imithi ye-Ayurvedic, izithasiselo zokudla).
Ngezansi kuneminye yemithi embalwa engase ihlangane nalo muthi. Lolu hlu aluphelele.
| Ungawuthathi lo muthi kanye nanoma yimuphi omunye umuthi. | |
|---|---|
| I-Artemether, i-lumefantrine | I-Ranolazine |
| I-Lurasidone | Eminye imithi enikezwa i-HIV kanye namagciwane e-Hepatitis C |
| Sicela wazise udokotela wakho ngoba lokhu kungase kuthinte imithi yakho. | |
| Amanye ama-antibiotic (isib. i-Clarithromycin, i-Erythromycin) | Ama-antifungal (isib. i-Fluconazole, i-Ketoconazole) |
| Imithi yesifo sokuwa (ukukhubazeka) (isib. i-Carbamazepine, i-Phenytoin) | Imithi yokucindezeleka noma ukukhathazeka |
| Ama-immunosuppressants (isib. i-Cyclosporine, i-Tacrolimus) | Izinhlobo zama-steroid (isb. i-Prednisone) |
| Amaphilisi okuvimbela inzalo (ama-hormone e-Estrogen/Progestin) | I-Warfarin (isidakamizwa esinciphisa igazi) |
| Izibulala-zinhlungu ezifana ne-ibuprofen | I-St. John's Wort (umuthi wamakhambi) |
Ezinye izinto okufanele uzicabangele lapho uthatha umuthi
- Ukuhlolwa njalo kwezokwelapha: Udokotela wakho uzokutshela ukuthi uze emtholampilo njalo. Hamba ngesikhathi esifanele bese wenza izinto ezifana nokuhlolwa kwegazi. Uma izimpawu zakho zingapheli, mtshele ngakho.
- Qaphela amehlo akho: Lo muthi unengozi encane yokubangela ama-cataract, ikakhulukazi ezinganeni. Ngakho-ke, kufanele uhlolwe amehlo akho ngudokotela wamehlo ngezikhathi ezithile ngenkathi uthatha umuthi. Uma ubona noma yiziphi izinguquko emehlweni akho, tshela udokotela wakho ngokushesha.
- Qaphela ngokulawula inzalo: Lokhu kubaluleke kakhulu uma usebenzisa amaphilisi okulawula inzalo angama-hormone. I-ORKAMBI ingase iwenze angasebenzi kahle. Ngakho-ke, qiniseka ukuthi ukhuluma nodokotela wakho mayelana nokusebenzisa uhlobo olwengeziwe lokulawula inzalo, njengekhondomu noma i-diaphragm .
Imiphumela emibi engase ivele ngenxa yemithi
Njenganoma yimuphi umuthi, lo ungabangela imiphumela emibi kwabanye abantu. Eminye iyingozi, eminye ivamile.
| Imiphumela emibi kakhulu okufanele ibikwe kudokotela ngokushesha | |
|---|---|
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe, ulimi noma umphimbo. |
| Ubunzima bokuphefumula noma ubuhlungu besifuba | Uma unenkinga yokuphefumula noma uzwa isifuba sakho siqina. |
| Izimpawu zokulimala kwesibindi | Ubuhlungu engxenyeni engenhla kwesokudla yesisu, ukulahlekelwa yisifiso sokudla, isicanucanu, indle enombala okhanyayo, umchamo ophuzi noma onsundu omnyama, ukuphuzi kwamehlo noma isikhumba, kanye nokukhathala okukhulu. |
| Umfutho wegazi okhuphukile | Udokotela uzokuhlola lokhu. |
| Ushintsho ekubukeni kwamehlo | Uma umbono wakho ubonakala ungacacile. |
| Imiphumela emibi evame ukungaphuthumi, kodwa okufanele ibikwe kudokotela uma iqhubeka | |
| Isisu esibuhlungu | Igesi |
| Uhudo | Isicanucanu |
| Ikhanda elibuhlungu | Ukukhathala |
| Imijikelezo yokuya esikhathini engajwayelekile kwabesifazane | |
Uwugcina futhi uwulahla kanjani umuthi?
- Indawo Yokugcina: Gcina amaphilisi kude nezingane nezilwane ezifuywayo . Gcina ekamelweni lokushisa (phakathi kwama-degree Celsius angu-20-25). Ungasebenzisi umuthi ophelelwe yisikhathi.
- Ukulahlwa: Indlela engcono kakhulu yokulahla imithi esiphelelwe yisikhathi noma engasadingeki ukukhipha amaphilisi esitsheni, uwaxube nento efana nekhofi esetshenzisiwe, inhlabathi, noma udoti wekati, uwafake esikhwameni esivalwe kahle, bese uwaphonsa emgqonyeni kadoti. Ungayilahli imithi endlini yangasese ngaphandle kokuthi udokotela wakho akutshele ukuthi wenze kanjalo.
Umlayezo Wokuya Nawe Ekhaya
- Njalo thatha i-ORKAMBI (Lumacaftor; Ivacaftor) nokudla okunamafutha njengebhotela, ushizi, noma amaqanda.
- Lo muthi ungowakho kuphela. Ungawubelani nabanye abantu.
- Yazisa udokotela wakho ngayo yonke eminye imithi, amavithamini, kanye nemithi yamakhambi oyithathayo.
- Funa usizo lwezokwelapha ngokushesha uma uhlangabezana nemiphumela emibi kakhulu njengokushintsha kombono, ubunzima bokuphefumula, noma ubuhlungu ohlangothini oluphezulu kwesokudla lwesisu sakho.
- Gcina izinsuku zakho ezihleliwe zomtholampilo kanye nokuhlolwa nodokotela wakho.
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