Ukwelashwa komdlavuza kuvame ukuba uhambo olunzima noluyinselele. Siyazi ukuthi imiphumela ehlukahlukene ingenzeka emzimbeni ngesikhathi salokhu kwelashwa. Kodwa-ke, kunemithi ekhethekile engakuvikela kuleyo miphumela emibi futhi isize ukwenza uhambo lube lula kuwe. Namuhla sizokhuluma "ngomsizi" onjalo ovikela ingxenye ebalulekile yomzimba wakho ngesikhathi sokwelashwa komdlavuza. Lowo umuthi wokugomela iMesna.
Uyini uMesna? Kalula nje...
Ake sithi unikezwa umuthi we-chemotherapy obizwa ngokuthi i-`ifosfamide` womdlavuza. Lo muthi unamandla kakhulu ekubulaleni amangqamuzana omdlavuza. Kodwa-ke, ungabangela nomonakalo othile kwesinye sakho, ikakhulukazi ukuphuma kwegazi ngomchamo wakho.
Yilapho umuthi obizwa ngokuthi iMesna ungena khona. IMesna akuyona umuthi womdlavuza. Isebenza "njengomqaphi" wesinye. Umsebenzi oyinhloko weMesna ukuvimbela umonakalo ongase ubangelwe umuthi `ifosfamide` esinyeni nokuvimbela ukuphuma kwegazi.
Okubalulekile, iMesna ivimbela kuphela ukuphuma kwegazi kwesinye okubangelwa umuthi i-`ifosfamide`. Ayikwazi ukuvimbela eminye imiphumela emibi yokwelashwa komdlavuza, njengokulahlekelwa izinwele kanye nesicanucanu.
Izinto ezibaluleke kakhulu okufanele uzitshele udokotela wakho ngaphambi kokusebenzisa lo muthi yilezi:
Ngaphambi kokuqala ukwelashwa kweMesna, kubalulekile ukuthi udokotela wakho azi kahle isimo sakho sempilo. Qiniseka ukuthi umtshela ngalokhu okulandelayo ikakhulukazi:
- Uma unesifo sokuzivikela komzimba: Isibonelo, uma unezifo ezifana ne-lupus, i-nephritis (isifo esithinta izinso), noma i-rheumatoid arthritis (isimo sokuvuvukala kwamalunga).
- Uma une-allergies: Tshela udokotela wakho uma une-allergy ku-Mesna, noma yiluphi uhlobo lwe-benzyl alcohol oluqukethwe yiyo, noma yimiphi imithi equkethe i-sulfur, noma yimiphi eminye imithi, ukudla, udayi, noma izithasiselo.
- Uma ukhulelwe, uzama ukukhulelwa, noma uncelisa: Kubaluleke kakhulu ukwazisa udokotela wakho ngalezi zimo.
Umuthi wokugomela iMesna unikezwa kanjani?
Lo muthi akuyona into ongayithatha uye nayo ekhaya. Ungumjovo onikezwa njengomjovo emthanjeni, njenge-saline. Ngakho-ke unikezwa uchwepheshe wezempilo esibhedlela noma emtholampilo. Ngakho-ke akudingeki ukhathazeke ngokulahlekelwa umthamo noma ukuphuthelwa umthamo.
Izingane zingadinga ukunakekelwa okukhethekile lapho zinikeza lo muthi. Udokotela wezingane uzonquma lokhu futhi akunike njengoba kudingeka.
Kuthiwani uma ngiphuza umuthi omningi kakhulu?
Lokhu kunikezwa esibhedlela, ngakho-ke amathuba okuba lokhu kwenzeke mancane kakhulu. Kodwa-ke, uma usola ukuthi uphuze ngokweqile, xhumana ngokushesha ne-National Poisons Information Centre e-Colombo National Hospital . Noma uye e -Emergency Treatment Unit (ETU) eseduze.
Izinto okufanele siziqaphele ngokukhethekile lapho sithatha lo muthi:
Udokotela wakho uzoqapha isimo sakho njalo ngesikhathi sokwelashwa kwakho kweMesna, futhi kubalulekile ukuthi uqaphele lezi zinkinga.
1. Phuza amanzi amaningi: Kufanele uphuze okungenani ilitha lamanzi (cishe izingilazi ezi-4) nsuku zonke ngenkathi uthatha lo muthi. Lokhu kuzosiza ukugcina isinye sakho sihlanzekile.
2. Qaphela umbala womchamo wakho: Uma ubona ukuthi umchamo wakho uphenduka upinki noma ubomvu, kungaba uphawu lokopha. Uma nje uqaphela lokhu, tshela udokotela wakho ngokushesha.
3. Izinguquko zesikhumba: Ngezinye izikhathi ukusabela okukhulu kwesikhumba kungenzeka ngisho namasonto ngemuva kokuqala lo muthi. Qaphela lezi zimpawu:
- Ukuqhuma okungazelelwe okunezimpawu ezifana nomkhuhlane kanye nokubanda.
- Izilonda ziba bomvu noma zibe nsomi, bese zikhula zibe amabhamuza noma isikhumba siphume.
- Isikhumba esibomvu nesilumayo esinama-lymph node avuvukele ebusweni, ezindebeni, entanyeni, noma emakhwapheni.
Uma ubona into efana nale, funa iseluleko sezokwelapha ngokushesha.
Yimiphi imiphumela emibi engaba khona?
Njenganoma yimuphi umuthi, iMesna ingabangela imiphumela emibi. Eminye yale miphumela kufanele ibikwe ngokushesha, kanti eminye ayibi kangako.
| Umphumela Ongemuhle |
|---|
| Imiphumela emibi kakhulu okufanele ibikwe kudokotela wakho ngokushesha |
| Ukusabela kokungezwani komzimba okufana nokuqubuka kwesikhumba, ukulunywa noma ukuqubuka, ukuvuvukala kobuso, izindebe noma ulimi |
| Ubunzima bokuphefumula |
| Igazi emchameni noma umchamo opinki/obomvu |
| Umkhuhlane, ukubanda, noma umphimbo obuhlungu |
| Ukubomvu kwesikhumba noma ukushawa |
| Izilonda zomlomo |
| Ubuhlungu noma ukubomvu endaweni yokujova |
| Ukubomvu, ukuqubuka, ukuxebuka kwesikhumba (ngisho nangaphakathi emlonyeni) |
| Ukuvuvukala kweqakala noma unyawo |
| Ukuhlanza |
| Imiphumela emibi okufanele ibikwe kudokotela uma iqhubeka noma ikhathaza |
| Ubuhlungu nobuhlungu bomzimba |
| Ukuzwa ukunambitheka okungathandeki emlonyeni |
| Uhudo |
| Isiyezi |
| Ukulahlekelwa izinwele |
| Ikhanda elibuhlungu |
| Isicanucanu |
Uma uhlangabezana nanoma yiziphi ezinye izimpawu ezingavamile ezingashiwongo kulolu hlu, sicela wazise udokotela wakho ngazo.
Umlayezo Wokuya Nawe Ekhaya
- I-Mesna ayiyona imithi yomdlavuza. Iwumuthi ovikelayo ovimbela umonakalo wesinye obangelwa umuthi womdlavuza i-`ifosfamide`.
- Ngaphambi kokuqala ukwelashwa, tshela udokotela wakho ngazo zonke izimo zakho zezokwelapha kanye nokungezwani komzimba.
- Ungakhohlwa ukuphuza amanzi amaningi ngezinsuku othatha ngazo lo muthi.
- Uma umchamo wakho uphenduka obomvu/opinki noma ubona ukusabela okukhulu kwesikhumba, yazisa udokotela wakho ngokushesha.
- Njengoba lo muthi unikezwa esibhedlela, akudingeki ukhathazeke ngokulahlekelwa umthamo noma ukuwugcina.
- Uma unemibuzo noma ukungabaza ngalo muthi, ungesabi ukubuza udokotela wakho.
👩🏽⚕️ Imibuzo eyengeziwe (ama-FAQ)
💬 Umuthi/amaphilisi eMesna/Mesnex umuthi okhethekile kakhulu onikezwa yisiphi isifo?
Lona akusiwo umuthi ojwayelekile wephilisi/wokulwa nomdlavuza! Lona umuthi kuphela osindisa impilo (i-Chemoprotectant) ongamisa i-Hemorrhagic Cystitis (ukopha ngomchamo) futhi 'uvikele isinyi ngo-100%' ezigulini ezinomdlavuza ezinikezwa imijovo yomdlavuza enamandla kakhulu/enamandla ebizwa ngokuthi 'i-Cyclophosphamide (Cytoxan)' kanye ne-'Ifosfamide', okubangelwa ubuthi obubulalayo (i-Acrolein) obukhiqizwa yileyo mijovo, elimaza ngokuphelele isinyi sesiguli futhi ibangele ukopha!
💬 Uma imijovo yomdlavuza izoshisa esinyeni, lo mjovo (Mesna) uwuvikela kanjani esinyeni?
Uma umuthi wokugomela umdlavuza (i-Ifosfamide) unikezwa umzimba, ukhiqiza ubuthi obubizwa ngokuthi 'i-Acrolein' obukhulu kangangokuthi bushisa inyama yesinye. Lobu buthi buya esinyini. Kodwa uma lo mjovo 'we-Mesna' unikezwa ngaphambi kokuba umuthi womdlavuza unikezwe, uya ngqo esinyini (iqembu le-Thiol libopha i-Acrolein) bese uguqula lobo buthi obubi bube yinto engenangozi, njengamanzi amnandi! Khona-ke leyo mijovo yomdlavuza izobulala umdlavuza kuphela futhi ingalimazi esinyeni.
💬 Yimiphi imibono eyiphutha kanye nemiphumela emibi engabekezeleleki okufanele abantu abasebenzisa lo muthi (iMesna) baqaphele ngokuqinisekile?
Umbono ongalungile omkhulu ukuthi lokhu akuzivikeli izitho zomzimba ngaphandle kwesinyi (isibindi, izinso, imizwa) ezingozini zalowo muthi womdlavuza (ezinye izifo zizofika noma kunjalo)! Futhi, ngemva kokuthatha lo muthi, abanye abantu bangase babe ne-allergy (Hypersensitivity) futhi babe namaqhubu emzimbeni wonke futhi umfutho wegazi wabo ungase wehle uye ku-zero. Enye into ecasulayo ukuthi noma ngabe uwuthatha ngomlomo noma uwujova, ngokuqinisekile uzoba 'nesicanucanu/ukuhlanza' okungabekezeleleki.
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