Kuyini i-Necrosis? Ake sifunde ngokufa kwamaseli akho!

Wake wezwa igama elithi ``necrosis''? Mhlawumbe walizwa kudokotela, noma walifunda ndawana thize. Kalula nje, lisho ukufa kwamaseli emzimbeni wethu. Kungase kwesabe kancane ukulizwa, kodwa uma usuliqonda, lingachaza okuningi. Ake sibone ukuthi liyini.

Kuyini ngempela i-necrosis?

Kalula nje, i-necrosis ukufa kwamaseli ezicutshini zomzimba wakho. Lokhu kungenzeka ngezizathu eziningi. Ngezinye izikhathi kungabangelwa ukulimala, ukutheleleka, noma uhlobo oluthile lwesifo. Kungabangelwa futhi ukuntuleka kokugeleza kwegazi ezicutshini, noma izinto ezinjengokubanda okukhulu noma ukushisa endaweni ezungezile. Into eyodwa okufanele uyikhumbule ukuthi yize izicubu ezifile zingasuswa, azikwazi ukubuyiselwa esimweni sazo.

Yiziphi izinhlobo ezahlukene ze-necrosis ezitholakalayo?

Uma amangqamuzana emzimbeni wakho efa ngenxa ye-necrosis, avela ngezindlela ezahlukene kanye nokubonakala. Lawa maseli afile angabonakala ngezindlela eziyisithupha eziyinhloko. Ake sibheke ukuthi ayini:

1. I-coagulative necrosis

Okwenzekayo ukuthi amangqamuzana afile ahlala eqinile futhi abonakale ejwayelekile izinsuku eziningi, njengokungathi akwenzekanga lutho. Lokhu kungenzeka uma kukhona ukugeleza kwegazi okunciphile noma ukuntuleka komoya-mpilo kunoma iyiphi ingxenye yomzimba wakho ngaphandle kobuchopho bakho.

2. I-necrosis ebangelwa uketshezi

Kulokhu, amangqamuzana afile ayancibilika phakathi namahora ambalwa, ngokuphelele noma ngokwengxenye. Abe esephenduka uketshezi olujiyile nolunamathelayo. Ngezinye izikhathi angabonakala ephuzi, ngoba ubomvu buyakheka. Ukutheleleka kanye nokuntuleka komoya-mpilo ebuchosheni yizona zimbangela eziyinhloko zalokhu.

3. I-Fat necrosis

Kulokhu, ama-enzyme akhishwa emaselini alimele, awaguqule abe uketshezi. Lawa maseli oketshezi ahlangana ne-calcium ukuze akhe ama-deposit amhlophe afana ne-chalk. I-pancreatitis ebukhali iyimbangela eyinhloko yalokhu. Ingabonakala nasezicutshini zebele.

4. I-Caseous necrosis

Kulokhu, amangqamuzana afile abonakala emhlophe futhi enamaqhubu. Abizwa ngokuthi afana noshizi - igama elithi `caseous` lisho `afana noshizi'. Lokhu kubonakala ikakhulukazi ekuthelelekeni kwamaphaphu `Isifo sofuba` .

5. I-Fibrinoid necrosis

Kulokhu, amangqamuzana afile abonakala ebomvana futhi engajwayelekile. Lokhu kungenxa yokuthi amaprotheni e-plasma (ama-fibrin) ayavuza emithanjeni yakho yegazi. Lokhu kungenzeka uma imithambo yakho yegazi yonakele, kungaba ngenxa yesifo sokuzivikela komzimba noma ukutheleleka.

6. I-Gangrenous necrosis

Kulokhu, isikhumba sakho siba mnyama bese siqala ukubola.Lokhu kungenzeka uma igazi eliya emilenzeni linqamuka. Ngezinye izikhathi kungathinta nezandla neminwe.

Yiziphi izinhlobo ezahlukene ze-necrosis?

I-necrosis ingathinta izingxenye eziningi ezahlukene zomzimba wakho. Amathambo, isikhumba, nezitho zangaphakathi kumane nje kuyizimbalwa zazo. Ake sibheke izinhlobo ezahlukene:

I-Avascular necrosis noma i-osteonecrosis

Lokhu kunamagama amaningi. I-Osteonecrosis, i-aseptic necrosis, kanye ne-bone necrosis wonke amagama avamile alokhu. Lokhu kwenzeka lapho ukunikezwa kwegazi ezicutshini zethambo kuyeka. Bese ithambo liphuka kancane kancane bese liyafa. I-hip necrosis uhlobo oluvame kakhulu lwalokhu.

I-Osteonecrosis yomhlathi (ONJ)

Lokhu futhi uhlobo lwe-avascular necrosis. Lesi sifo somlomo sibangelwa ukufa kwamaseli ethanjeni lomhlathi. Lokhu kungabangela ubuhlungu obukhulu emlonyeni nasemhlathini. Kungabangela nokuthi ubomvu buphume emlonyeni nasemhlathini.

I-pancreatic necrosis

Lokhu kuyinkinga enkulu ye-pancreatitis ebukhali. Uma ukuphakelwa kwegazi ku-pancreas kunqanyulwa, izicubu ze-pancreas zingafa. Uma lokho kwenzeka, i-pancreas ingatheleleka. Ukutheleleka kungasakazekela egazini (i-sepsis) futhi kubangele ukwehluleka kwezitho zomzimba.

I-necrosis yamafutha esifubeni

Lesi yisimo esingenabungozi. Kungenzeka uma izicubu ezinamafutha ebeleni zonakele. Ngokuvamile, izicubu ezibomvu zakha esikhundleni sezicubu zebele ezonakele. Kodwa-ke, kulokhu, amanye amaseli amafutha ayafa esikhundleni sokwakha izicubu ezibomvu. Bese kuba khona iqhubu eligcwele uketshezi olunamafutha (i-'oil cyst').

I-acute tubular necrosis (ATN)

Lesi yisifo sezinso. Ukwehluleka okukhulu kwezinso kungenzeka lapho amaseli e-tubule ezinso zakho ewohloka. Lawa ma-tubule angamapayipi amancane asiza ukuhlunga igazi njengoba lidlula ezinso.

I-necrosis yemisebe

Lokhu kuwumphumela ongavamile wokwelashwa ngemisebe esezingeni eliphezulu ebuchosheni, ekhanda nasentanyeni. Kungabangela ukufa kwezicubu zobuchopho unomphela.

I-renal papillary necrosis

Lesi futhi yisifo sezinso. Sivela lapho izingxenye zezinso ezibizwa ngokuthi i-renal papillae zifa. Ama-renal papillae yizimbobo ezisezimbotsheni ezingena ezinso bese zithwala umchamo ziye esinyeni.

I-necrosis yesikhumba noma i-gangrene

Lokhu kwenzeka lapho ukugeleza kwegazi kuya ezicutshini zomzimba noma ezithweni zangaphakathi kuyeka.Kungabangelwa futhi ukutheleleka ngamagciwane. Ngokuvamile kuthinta iminwe, izinzwane, izandla nezinyawo, kodwa kungathinta noma iyiphi ingxenye yomzimba.

I-necrosis yokulunywa yizicabucabu

Lokhu kungenzeka uma ulunywe izinhlobo ezithile zezicabucabu (isb., isicabucabu i-Recluse). Ubuthi balezi zicabucabu bungabangela inxeba elibolisa isikhumba. Kodwa-ke, i-necrosis evela ekulunyweni kwesicabucabu ayivamile.

I-Pulp necrosis

Lokhu kwenzeka lapho izicubu ezithambile (`i-pulp`) ngaphakathi kwezinyo zifa. Ngaphakathi kwezinyo ngalinye kukhona igumbi eliqukethe izingcezu ezincane zenyama. Ngaphakathi kwalawo magumbi kukhona imithambo yegazi nemizwa. Uma izinyo lilimele noma libolile, lelo pulp lingangenwa yileli gciwane bese liyafa.

Uyini umehluko phakathi kwe-Apoptosis ne-Necrosis?

I-Apoptosis kanye ne-necrosis zombili izindlela amaseli afa ngazo.

• I-Apoptosis iyindlela evamile nenempilo yokuthi amaseli afe. ​​Afa ngokwemvelo ukuze kugcinwe ibhalansi yamaseli emzimbeni. I-Apoptosis ibalulekile ukuze umzimba usebenze kahle. Ayidingi ukwelashwa njalo.
• I-Necrosis ukufa okungazelelwe kwamaseli, kungaba ngaphakathi noma ngaphandle komzimba. Kungabangelwa izifo, ukutheleleka, noma ukulimala. Lezi zimo zonakalisa izindonga zamaseli, ziwavimbele ekusebenzeni kahle. I-Necrosis ngokuvamile idinga ukwelashwa.

Cabanga ngale ndlela: I-Apoptosis ifana nokubhidlizwa kwesakhiwo esidala okuhleliwe. Kodwa i-Necrosis ifana nokubhidlika kwesakhiwo engozini.

Kuyini i-Tumor Necrosis Factor (TNF)?

I-Tumor Necrosis Factor (TNF) iyiprotheni esetshenziswa amasosha omzimba wakho ukulwa nokutheleleka. Lapho amangqamuzana athile amhlophe egazi etheleleka, akhipha i-TNF, okubonisa amanye amangqamuzana omzimba ukuthi alwe nokutheleleka. Ukuvuvukala kwenzeka futhi amangqamuzana aqala ukulwa nokutheleleka. I-TNF nayo itholakale ukuthi iyakwazi ukubangela i-necrosis kwezinye izinhlobo zamangqamuzana omdlavuza. Lokhu kufundwa kabanzi ekwelapheni ezinye izinhlobo zomdlavuza.

Ziyini izimpawu ze-necrosis ngemva kokujova nge-filler?

Ama-dermal fillers, ikakhulukazi imijovo ye-hyaluronic acid, ayizinqubo ezincane zobuhle ezisetshenziselwa ukukhuluphala nokukhuluphala kwesikhumba. Nakuba zivame ukusetshenziswa, izinkinga azivamile. Kodwa-ke, kwezinye izimo, i-necrosis iye yaba khona. Izimpawu ze-necrosis zingavela ngokushesha noma emahoreni ambalwa ngemva kokujova i-filler. Lezi zimpawu zifaka:

• Okungaphezu kwalokho obekulindelwe ngemva kokwelashwaUkuzwa ubuhlungu obukhulu nokungakhululeki.
• Ukuzwa ubuhlungu obukhulu uma uthintwa.
• Isikhumba siyashintsha sibe mhlophe (sibe mhlophe).
• Amabala abomvu esikhumbeni.
• Isikhumba siphenduka sibe luhlaza okwesibhakabhaka noma sibe nsomi .

Uma unesinye noma ngaphezulu salezi zimpawu, kubaluleke kakhulu ukufuna iseluleko sezokwelapha ngokushesha.

Ngakho-ke, yini okufanele siyifunde kulokhu? (Umyalezo Wokuya Ekhaya)

I-Necrosis yigama lezokwelapha lokufa kwezicubu emzimbeni wakho. Ingaba nezimbangela eziningi. Futhi, ubukhali kanye nokwelashwa kwezinhlobo ezahlukene ze-necrosis kuyahlukahluka. Nakuba ezinye izimo ze-necrosis zingaxazululeka zodwa, kufanele nakanjani ubone udokotela uma uhlangabezana nanoma yiziphi izimpawu ze-necrosis. Ngoba ezinye izinhlobo ze-necrosis zidinga ukwelashwa okusheshayo. Udokotela angakwazi ukuxilonga isimo sakho futhi akunikeze ukwelashwa okudingekayo. Ngakho-ke, ungathathi lutho kalula, futhi uma uzizwa ungakhululekile, bona udokotela ngokushesha.

I- Necrosis, ukufa kwamangqamuzana, ukufa kwezicubu, i-gangrene, ukuhlinzekwa kwegazi, ukutheleleka