Kuyini i-norepinephrine? Ake sixoxe ngakho kalula!

Wake wazibuza ukuthi kwenzekani emzimbeni wakho uma uvele wesaba noma ukhathazeke ngokuzumayo? Noma yiziphi izinto ezikugcina uqaphile futhi ujabule? Kukhona ikhemikhali encane kodwa ebaluleke kakhulu ekhiqizwa emzimbeni wethu ehlobene nakho konke lokhu. Yi-norepinephrine, ebizwa nangokuthi i-noradrenaline ngabanye. Ake sibone ukuthi lokhu kubaluleke kangakanani emzimbeni wethu.

Iyini ngempela i-norepinephrine?

Kalula nje, le norepinephrine ifana nomuntu owenza izinto ezimbili emzimbeni wethu. Enye ukusebenza njenge -neurotransmitter . Enye ukusebenza njenge -hormone .

Cabanga ngale ndlela: i-neurotransmitter ifana nesithunywa. Isiza amangqamuzana ethu ezinzwa ukuthi axhumane. Ithwala imiyalezo esuka kwelinye iseli lezinzwa iye kwelinye, noma esuka eselini lezinzwa iye eselini lezindlala. Kufana nokuhambisa incwadi evela eposini.

Njenge-hormone, i-norepinephrine ikhiqizwa yizindlala zethu ze-adrenal . Lezi zitholakala phezu kwezinso zethu, njengesembozo. Lawa ma-hormone akhishwa ngqo egazini lethu futhi ahamba emzimbeni wonke ukuze enze imisebenzi eyahlukahlukene.

Njenge-neurotransmitter, i-norepinephrine ikhiqizwa kwenye ikhemikhali ebizwa ngokuthi i-dopamine . Lokhu kukhiqizwa kakhulu ngamaseli ezinzwa ebuchosheni naseduze komgogodla.

I-Norepinephrine iyingxenye yesimiso sethu sezinzwa esinozwela . Yilokhu okulawula impendulo yomzimba wethu "yokulwa noma ukubaleka" ngezikhathi eziphuthumayo, okungukuthi, ngezikhathi zengozi. Ngokwezokwelapha, lokhu kubizwa ngokuthi impendulo yokucindezeleka okukhulu .

Yini eyenziwa yi-norepinephrine emzimbeni?

Nazi ezinye zezinto eziyinhloko ezenziwa yi-norepinephrine njenge-neurotransmitter ebuchosheni bethu nasemgogodleni:

• Kukhulisa ukunaka kwethu, ukuphaphama, kanye nesithakazelo. Kukusiza ukuthi uhlale ugxile lapho ufunda noma wenza umsebenzi obalulekile.
• Kuncipha imithambo yegazi. Lokhu kusiza ukulawula umfutho wegazi ngezikhathi zokucindezeleka.
• Kuphinde kuthinte umjikelezo wethu wokulala nokuvuka, isimo sengqondo kanye nenkumbulo.

Yiziphi izinto ezithinta ukukhishwa kwe-norepinephrine?

Njenge-hormone, ukucindezeleka yisona sizathu esiyinhloko esenza izindlala zethu ze-adrenal zikhiphe i-norepinephrine. Lokhu kusabela kubangela izinguquko eziningi emizimbeni yethu. Yilokhu esikubiza ngokuthi impendulo "yokulwa noma ukubaleka" esikhulume ngakho ekuqaleni.

Iyini le mpendulo "yokulwa noma ukubaleka"?

Kalula nje, yile ndlela umzimba wethu olungiselela ngayo ukubhekana nengozi noma ukwesaba okungazelelwe. Cabanga ukuthi uhamba emgwaqweni bese kuthi kungazelelwe kufike inja enolaka ikuxosha. Bese kufanele ulwe nenja noma uyibalekele. Yilokhu okwenzeka ngaphakathi emzimbeni wethu esimweni esinjalo. Mhlawumbe uma kungazelelwe kufanele ukhulume phambi kwabantu abaningi, umzimba wakho ungase ube nalolu hlobo lokusabela.

Phakathi nale mpendulo "yokulwa noma ukubaleka", ubuchopho bakho buqala ukuqaphela ukuthi kukhona ingozi. Ngemuva kwalokho, imizwa e -hypothalamus yobuchopho bakho ithumela umlayezo ohamba ngomgogodla uye kuwo wonke umzimba wakho. Lo myalezo uphathwa yi-neurotransmitter esikhulume ngayo ebizwa ngokuthi i-norepinephrine. Le norepinephrine iya ezithweni nasezicutshini ezilandelayo, okubangela lezi zimpendulo ezisheshayo:

• Amehlo: Izimbotshana zamehlo ziba zinkulu, okuvumela ukukhanya okwengeziwe ukuthi kungene futhi okuvumela isilwane ukuthi sibone indawo esizungezile kangcono ukuze sigweme ingozi.
• Isikhumba: Isikhumba siba mhlophe. Okwenzekayo ukuthi imithambo yegazi ithunyelwa umlayezo wokuthumela igazi ezindaweni ezidinga umoya-mpilo owengeziwe, okungukuthi, emisipheni. Yilapho uthola khona amandla okulwa noma okugijima.
• Inhliziyo: Inhliziyo iqala ukushaya ngokushesha nangokuqinile. Leli gazi elinomoya-mpilo owengeziwe lithunyelwa ezindaweni ezidinga amandla, njengemisipha. Umfutho wegazi nawo uyakhuphuka ngalesi sikhathi.
• Imisipha: Imisipha ithola igazi nomoya-mpilo owengeziwe, okuyenza isebenze ngamandla nangejubane elengeziwe.
• Isibindi: I-Glycogen egcinwe esibindini iguqulwa ibe yi -glucose, inikeze amandla engeziwe.
• Umgudu wokuphefumula: Ukuphefumula kuyajula futhi kusheshe. Imigudu yomoya iyavuleka, okuvumela umoya-mpilo owengeziwe ukuthi ungene egazini, bese uhamba uye emisipheni.

Le neurotransmitter, i-norepinephrine, nayo iya endlaleni yethu ye-adrenal. Ibe isikhipha ama-hormone i-adrenaline (i-epinephrine) kanye ne-noradrenaline (i-norepinephrine). La ma-hormone ahamba egazini emzimbeni wonke aye emehlweni, enhliziyweni, endleleni yokuphefumula, emithanjeni yegazi esikhumbeni, bese ebuyela endlaleni ye-adrenal. "Umyalezo" onikezwa kulezo zitho zomzimba ukuthi wenze ngale ndlela uze ubalekele ingozi.

Empeleni lena incazelo elula kakhulu yempendulo "yokulwa noma ukubaleka". Ezinye izingxenye zesimiso sethu sezinzwa, ezinye izinhlelo zezitho zomzimba, ama-hormone, kanye nama-neurotransmitter nazo ziyabandakanyeka.

I-norepinephrine isetshenziswa kanjani njengomuthi?

I-Norepinephrine njengomuthi isetshenziswa ezimweni ezilinganiselwe, zesikhashana ukuze kwandiswe futhi kulondolozwe umfutho wegazi lapho umfutho wegazi ophansi uyinkinga. Lokhu kungenzeka ezimweni ezinjengalezi:

• Izimo ezifana nokuma kwenhliziyo
• Lapho kwenziwa i-anesthesia yomgogodla
• I-Septicemia, isimo sobuthi egazini
• Izinkinga ngokumpontshelwa igazi
• Ukusabela okubi kweminye imithi (Ukusabela kwemithi)

Ngokuvamile, i-norepinephrine isetshenziswa kanye neminye imithi kulezi zimo.

Ngaphezu kwalokho, i-norepinephrine nayo inikezwa njengokwelashwa kwezimo ezinzima ezifana nalezi:

• Ukushaqeka kwe-Septic: Lokhu kungaba yingozi empilweni, futhi kuyisimo lapho umfutho wegazi wehla ngendlela engavamile ngemva kokutheleleka.
• Ukushaqeka kwemizwa: Isimo esingaba yingozi empilweni esibangelwa ukulimala komgogodla.
• I-Pericardial tamponade: Isimo lapho uketshezi oluningi luqongelela khona emgodini ozungeze inhliziyo, okubeka ingcindezi enhliziyweni.
• Umfutho wegazi ophansi kakhulu (i-Critical hypotension).

Yimiphi imiphumela emibi engaba khona yokuthatha i-norepinephrine njengomjovo?

Uma kuthathwa njengomjovo we-norepinephrine, kunemiphumela eminingana emibi edinga ukunakekelwa kwezokwelapha. Lena yile:

• Ukusabela kokungezwani komzimba: Ukucasuka kwesikhumba, ukulunywa, ukuqubuka, ukuvuvukala kobuso, izindebe, noma ulimi.
• Ubunzima bokuphefumula, ukukhwehlela.
• Ukushaya kwenhliziyo okungajwayelekile, ukushaya kwenhliziyo okungapheli, noma ubuhlungu besifuba.
• Ubuhlungu, ukubomvu, noma ukuvuvukala lapho kujovwe khona.

Uma kwenzeka into efana nale, kufanele utshele udokotela ngokushesha.

Yiziphi izinkinga zempilo ezingaba khona uma amazinga e-norepinephrine ehla?

Uma izinga le-norepinephrine emzimbeni lehla, kungase kube nezinkinga zempilo ezilandelayo:

• Ukukhathazeka.
• Ukucindezeleka.
• Isifo sokungakwazi ukugxilisa ingqondo (ADHD).
• Ikhanda elibuhlungu.
• Izinkinga zememori.
• Izinkinga zokulala.
• Umfutho wegazi ophansi (i-Hypotension).
• Ushukela ophansi egazini (i-Hypoglycemia).
• Izinguquko ekucindezelweni kwegazi kanye nokushaya kwenhliziyo.
• Ukuntuleka kwe-dopamine beta-hydroxylase. Lesi yisifo esingavamile kakhulu esibangelwa izakhi zofuzo. Kulesi simo, umzimba wethu awukwazi ukwenza i-norepinephrine kusuka ku-dopamine.

Uma unalezi zimpawu, akusikho ukuthi unezinga eliphansi le-norepinephrine. Kodwa kungcono ukubona udokotela ukuze uthole iseluleko.

Kwenzekani uma amazinga e-norepinephrine enyuka?

Uma amazinga e-norepinephrine ekhuphuka emzimbeni, kungase kube nezimo ezilandelayo zempilo:

• Umfutho wegazi ophezulu (i-Hypertension).
• Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile.
• Ukujuluka ngokweqile.
• Isikhumba esibandayo noma esikhanyayo.
• Ikhanda elibuhlungu kakhulu.
• Ukungahlaliseki, ukuthuthumela.
• I-Pheochromocytoma: Lesi isimila esikhula endlaleni ye-adrenal.

Kuthiwa futhi abantu abanamazinga aphezulu e-norepinephrine basengozini enkulu yesifo senhliziyo, isifo semithambo yegazi kanye nokulimala kwezinso.

Yini ongayenza ukuze wandise amazinga e-norepinephrine ngokwemvelo?

Ungakhulisa amazinga akho e-norepinephrine ngokwemvelo ngokwenza izinto ezifana nalezi:

• Ukuzivocavoca okuvamile: Vivinya okungenani imizuzu engama-30 ngosuku, okungenani izinsuku ezinhlanu ngesonto. Cabanga ngokugijima, ukuhamba ngezinyawo, noma ukugibela ibhayisikili.
• Lala ngokwanele: Zama ukulala okungenani amahora ayisikhombisa kuya kwayisishiyagalombili ngosuku. Ukulala kahle kufana nomuthi womzimba nengqondo.
• Yidla ukudla okunomsoco: Faka ukudla okucebile ngamaprotheni njengenyama, inkukhu, inhlanzi, amantongomane (isb. ama-cashew, amantongomane), amaqanda, noshizi. Lokhu kuqukethe i-amino acid tyrosine, esiza ekwenzeni i-norepinephrine.
• Ukulalela umculo, ukwenza into ekwenza ujabule: Uma ulalela ingoma oyithandayo noma uhlanganyela ekuzilibaziseni, uzizwa ujabule. Kuthiwa uma ujabule, ukukhishwa kwe-norepinephrine kuyanda.

Yikuphi ukufana nomehluko phakathi kwe-Epinephrine ne-Norepinephrine?

I-Norepinephrine iyi-neurotransmitter kanye ne-hormone, kodwa ngokuyinhloko isebenza njenge-neurotransmitter. I-Norepinephrine, eyaziwa nangokuthi i-noradrenaline, ibalulekile ekusabeleni komzimba wakho "ukulwa noma ukubaleka". Njengomuthi, i-norepinephrine isetshenziselwa ukwandisa nokugcina umfutho wegazi ezimweni zempilo ezilinganiselwe, zesikhashana, nezibucayi.

I-Epinephrine, eyaziwa nangokuthi i-adrenaline, iyi-hormone kanye ne-neurotransmitter. Zombili zikhiqizwa yizindlala ze-adrenal, futhi zombili zisabela ekucindezelekeni. Kodwa-ke, i-epinephrine isebenza ngokuyinhloko njenge-hormone , ithinta inhliziyo kakhulu kune-norepinephrine,Ithinta indlela umzimba osebenza ngayo. I-Norepinephrine isebenza kahle kakhulu ekucindezeleni imithambo yegazi nasekugcineni umfutho wegazi uphezulu.

Kalula nje, laba ababili bafana nabafowethu ababili abasebenza ndawonye, ​​kodwa imisebenzi yabo eyinhloko ihlukile kancane.

Okokugcina, izinto okufanele uzikhumbule

Ngakho-ke, cishe usuyaqonda manje ukuthi i-norepinephrine iyikhemikhali encane kodwa enamandla kakhulu emizimbeni yethu. Idlala indima enkulu kukho konke kusukela ekusigcineni siqaphile empendulweni "yokulwa noma yokubaleka" esisiza ukuba sisinde uma kwenzeka ingozi.

Kungakhathaliseki ukuthi izinga liphansi kakhulu noma liphezulu kakhulu, izinkinga zempilo zingavela. Ngakho-ke, kubalulekile ukuzama ukugcina lokhu kulinganisela. Singasiza ngalokhu ngezinto ezilula njengokulala kahle, ukuzivocavoca umzimba, ukujabula, kanye nokudla okulinganiselayo.

Uma unemibuzo noma ukungabaza ngalokhu, into engcono kakhulu ongayenza ukubonana nodokotela. Bangakunikeza iseluleko esifanele.

Ngakho-ke, ukuqaphela lezi zinto ezimangalisayo ezenzeka emizimbeni yethu kubaluleke kakhulu empilweni enempilo!

I- Norepinephrine, i-noradrenaline, i-neurotransmitter, i-hormone, ukulwa noma ukubaleka, ukucindezeleka, umfutho wegazi