Namuhla, inkinga yezempilo abantu abaningi ezweni lethu abanayo yisifo sikashukela sohlobo lwesibili. Ngakho-ke, njengokwelashwa kwalokhu, sivame ukusebenzisa amaphilisi kanye nemijovo ye-insulin. Kodwa muva nje, kuqaliswe umuthi omusha ophuzwayo owenze umehluko omkhulu ezindleleni zokwelapha isifo sikashukela. Namuhla, sizokhuluma ngalowo muthi, i-Rybelsus. Udokotela wakho kungenzeka ukuthi ukuncomile lokhu, noma kungenzeka ukuthi uke wezwa ngakho. Ake sizame ukuqonda konke ngalo muthi ngendlela elula.
Uhlobo luni lomuthi iRybelsus?
Kalula nje, i-Rybelsus iyisidakamizwa esisesigabeni semithi ebizwa ngokuthi “ama-agonist e-Glucagon-like peptide-1 (GLP-1).” Isithako esisebenzayo kuyo yi-semaglutide. Nakuba igama lingase lizwakale liyinkimbinkimbi kancane, indlela esebenza ngayo ilula kakhulu.
Cabanga nje, imizimba yethu ikhiqiza ngokwemvelo i-hormone ebizwa ngokuthi i-GLP-1. Le hormone isiza ukulawula amazinga ethu kashukela egazini ngemva kokudla. Lokho okwenziwa yi-Rybelsus ukuthi isebenza njengaleyo hormone yemvelo. Okusho ukuthi, ibopha kuma-receptor e-GLP-1 emizimbeni yethu futhi isebenza njenge-hormone yethu.
Ngaphambilini, lolu hlobo lwemithi ye-GLP-1 lwalutholakala kuphela njengomjovo. Kodwa i-Rybelsus iyisidakamizwa sokuqala nesodwa se-GLP-1 esiza ngesimo sephilisi esingathathwa ngomlomo . Lokhu kuyintuthuko enkulu ekwelapheni isifo sikashukela.
Lo muthi ulawula kanjani amazinga kashukela egazini?
I-Rybelsus yehlisa amazinga kashukela egazini lakho, noma i-glucose, ngezindlela ezintathu eziyinhloko.
- Ukukhuthaza ukukhiqizwa kwe-insulin yi-pancreas: Ngemva kokudla, lo muthi utshela i-pancreas yakho ukuthi ikhiqize inani elidingekayo le-insulin. I-insulin iyi-hormone esiza ushukela egazini ukuthi ungene emangqamuzaneni, yehlise amazinga kashukela egazini.
- Kuvimbela ukukhishwa kukashukela esibindini: Isibindi sethu sigcina ushukela. Ngezinye izikhathi lo shukela ogciniwe ukhishwa ngokungadingekile egazini. I-Rybelsus ilawula le nqubo.
- Ukunciphisa ukunyakaza kokudla: Lo muthi wehlisa ijubane ukudla okudlayo okuhamba ngalo esiswini nasemathunjini akho. Lokhu kusho ukuthi ushukela ovela ekudleni awumuncwa egazini lakho ngesikhathi esisodwa, kodwa kancane kancane. Lokhu kusiza ukulawula ukwanda okungazelelwe koshukela egazini ngemva kokudla.
Uyisebenzisa kanjani iphilisi le-Rybelsus?
Lena yinto ebaluleke kakhulu futhi ebaluleke kakhulu okufanele uyiqaphele lapho uthatha lo muthi. Le miyalelo kumele ilandelwe ngqo, ngaphandle kwalokho ukusebenza kahle komuthi kungancipha.
I-Rybelsus kufanele ithathwe njalo ekuseni, esiswini esingenalutho. Lokhu kusho okungenani imizuzu engama-30 ngaphambi kokudla kokuqala, isiphuzo (ngaphandle kwamanzi), noma yimuphi omunye umuthi wosuku.
Leli philisi kufanele liphuzwe ngamanzi angaphansi kwama-ounces angu-4 (cishe amamililitha angu-120) . Gwinya iphilisi lonke . Ungaliphuli, ulichoboze, noma ulihlafune .
Uma ulinda imizuzu engaphansi kwengu-30, noma uma uyiphuza nokudla, isiphuzo esingesiwo amanzi, noma eminye imithi, inani le-Rybelsus elimuncwa ngumzimba lingancipha, futhi umuthi ungase unganikezi umphumela ofiselekayo.
Udokotela wakho uvame ukuqala ngo-3 milligrams (mg) we-insulin ezinsukwini zokuqala ezingama-30 ukusiza umzimba wakho ukuthi ujwayele umuthi. Ngemuva kwalokho, umthamo uzonyuswa ube ngu-7mg. Udokotela wakho angandisa umthamo ube ngu-14mg uma kudingeka, kuye ngamazinga kashukela egazini lakho kanye nemiphumela yokuhlolwa kwe -HbA1c .
Kuyini i-HbA1c?
I-HbA1c ukuhlolwa kwegazi okubonisa amazinga akho ajwayelekile kashukela egazini ezinyangeni ezi-2-3 ezedlule . Kufana 'nekhadi lombiko' lokulawula ushukela egazini lakho. Ukulawula leli nani kungasiza ekunciphiseni ingozi yakho yokuthola izinkinga ezihlobene nesifo sikashukela (njengesifo senhliziyo nesifo sezinso).
Yiziphi izinzuzo zeRybelsus?
Izifundo zezokwelapha ngeRybelsus zikhombisile ukuthi lo muthi, kungakhathaliseki ukuthi uthathwa wodwa noma neminye imithi yesifo sikashukela, uyasiza ekunciphiseni amazinga e-HbA1c kanye nesisindo somzimba.
Amathebula angezansi abonisa imiphumela yalezi zifundo. Kodwa khumbula, lena imiphumela emaphakathi futhi imiphumela yakho ingahluka .
| Ukuqhathaniswa phakathi kweRybelsus neminye imithi | ||
|---|---|---|
| Umuthi oqhathaniswayo | Inani le-HbA1c elinciphile | Ukwehlisa isisindo |
| I-Rybelsus engu-14mg uma iqhathaniswa ne- Jardiance (empagliflozin) engu-25mg | I-Rybelsus yehlise amazinga e-HbA1c kakhulu . | Ukwehlisa isisindo kwakufana kuzo zombili. |
| I-Rybelsus engu-7mg noma engu-14mg uma iqhathaniswa ne -Januvia (sitagliptin) engu-100mg | I-Rybelsus yehlise amazinga e-HbA1c kakhulu . | I-Rybelsus yabangela ukwehla kwesisindo okwengeziwe . |
| I-Rybelsus engu-14mg uma iqhathaniswa nomjovo we -Victoza (liraglutide) ongu-1.8mg | Ukwehla kwe-HbA1c bekufana . | I-Rybelsus yabangela ukwehla kwesisindo okwengeziwe . |
Le miphumela ikhombisa ukuthi i-Rybelsus iyisidakamizwa esingasiza ekulawuleni ushukela egazini kanye nokwehlisa isisindo ngezinga elithile.
Yiziphi imiphumela emibi ye-Rybelsus nokuthi ungayiphatha kanjani?
Njenganoma yimuphi umuthi, i-Rybelsus ingaba nemiphumela emibi. Evame kakhulu yile:
- Isicanucanu
- Isisu esibuhlungu
- Uhudo
- Isifiso sokudla
- Ukuhlanza
- Ukuqunjelwa
Lokhu kufaka phakathi isicanucanu, ukuhlanza, kanye nesifo sohudo, okuvamile lapho uqala ukuthatha imithi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu, phuza uketshezi oluningi ukuze uvimbele ukuphelelwa amanzi emzimbeni . Uma lezi zimpawu ziqhubeka noma ziba zimbi kakhulu, khuluma nodokotela wakho.
Amathiphu okuphatha imiphumela emibi
- Gwema ukudla okunamafutha, okunoshukela omningi, kanye nokudla okunongwe kakhulu.
- Esikhundleni sokudla okuningi ngesikhathi esisodwa, yidla ukudla okuncane okuningana.
- MaMonki, yidlani ukudla kwenu ngokucophelela.
- Ungalali phansi ngokushesha ngemva kokudla.
- Yidla ukudla okulula (isib. isobho, iyogathi, isinkwa esithosiwe, ilayisi).
- Gwema amaphunga anamandla (amaphunga asegadini, amaphunga amakha, amaphunga entuthu).
Yiziphi izimo ezikhethekile okufanele uziqaphele?
I-Pancreatitis
Uma uzwa ubuhlungu obukhulu esiswini obungabekezeleleki futhi busakazekela emhlane wakho, kanye nokuhlanza, yeka ukuthatha i-Rybelsus ngokushesha bese utshela udokotela wakho. Lokhu kungaba uphawu lwesimo esibi esibizwa ngokuthi i-pancreatitis.
Ushukela ophansi egazini (i-Hypoglycemia)
Uma uthatha i-Rybelsus kanye ne-insulin noma eminye imithi ethile yesifo sikashukela (njenge-sulfonylureas), izinga likashukela egazini lakho lingase libe phansi kakhulu (i-hypoglycemia). Buza udokotela wakho ukuthi izinga likashukela egazini lakho liphansi kangakanani.
Uma ushukela wakho wegazi uphansi, yidla ushukela. Isibonelo, ungathatha amaphilisi e-glucose, ijusi yezithelo, ushukela, noma ithisipuni elilodwa loju. Uma unezinye zezimpawu ezilandelayo noma uma izinga lakho likashukela egazini liphansi, khuluma nodokotela wakho.
| Izimpawu zoshukela ophansi egazini (i-Hypoglycemia) | |
|---|---|
| - Isiyezi | - Indlala enkulu |
| - Ukuthuthumela | - Ukushaya kwenhliziyo okusheshayo |
| - Ukujuluka | - Ukulala ngokweqile |
| - Ukungahlaliseki, ukucasuka | - Ikhanda elibuhlungu |
Amanye amaphuzu
- Ukukhulelwa: Tshela udokotela wakho uma uhlela ukukhulelwa. Kufanele uyeke ukuthatha i-Rybelsus okungenani izinyanga ezimbili ngaphambi kokukhulelwa.
- Eminye imithi: I-Rybelsus ingase ithinte indlela umzimba wakho omunca ngayo eminye imithi oyiphuza ngomlomo. Ngakho-ke uma ubona ushintsho endleleni eminye imithi oyiphuza ngayo isebenza, khuluma nodokotela wakho ngalokho.
I-Rybelsus umuthi kadokotela okufanele uthathwe kuphela ngomuthi kadokotela. Udokotela wakho uzonquma ukuthi lo muthi ukulungele yini ngokusekelwe esimweni sakho sempilo, amazinga kashukela egazini, nezinye izici.
Umlayezo Wokuya Nawe Ekhaya
- I-Rybelsus umuthi omusha ophuzwayo wesifo sikashukela sohlobo 2.
- Lokhu kufanele kuthathwe njalo ekuseni esiswini esingenalutho, imizuzu engama-30 ngaphambi kwanoma yini enye, ngamanzi amancane. Ungaliphuli, ulichoboze, noma ulihlafune iphilisi.
- Lokhu kunciphisa amazinga kashukela egazini (i-HbA1c) futhi kungasiza nasekunciphiseni isisindo.
- Kuvamile ukuba nemiphumela emibi efana nokucanuzela kwenhliziyo, ukuhlanza, kanye nesifo sohudo lapho uqala umuthi.
- Funa usizo lwezokwelapha ngokushesha uma uzwa ubuhlungu obukhulu esiswini (uphawu lwe-pancreatitis) noma izimpawu zoshukela wegazi ophansi (hypoglycemia).
- Landela imiyalelo kadokotela wakho ngqo ngaso sonke isikhathi. Gwema ukuzelapha.
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