Sonke siyazi ukuthi ukulwa nomdlavuza akulula. Phakathi nalolu hambo, udokotela wakho angakunikeza imithi ehlukahlukene. I-Sunitinib ingenye yemithi enjalo, ehlasela amangqamuzana omdlavuza futhi imise ukukhula kwawo. Ngakho-ke, uma unikezwe lo muthi kalula nangokucacile kuzoba usizo olukhulu ohambweni lwakho lokwelashwa. Ake sixoxe ngalokhu.
Uhlobo luni lomuthi i-Sunitinib?
Kalula nje, i-Sunitinib iyisidakamizwa esiwela esigabeni "sokwelashwa okuqondiwe." Lokhu kusho ukuthi lesi sidakamizwa asigcini nje ngokuthinta wonke amaseli emzimbeni, kodwa kunalokho sihlonza futhi simise amaprotheni athile asiza amangqamuzana omdlavuza ukuba akhule futhi asakazeke. Lokhu kufana nokuhlasela isitha ngqo.
Lo muthi usetshenziswa kakhulu ukwelapha izinhlobo ezilandelayo zomdlavuza:
- I-GIST (Izimila Zesisu): Lolu uhlobo oluthile lwesimila oluvela ohlelweni lwethu lokugaya ukudla.
- Umdlavuza Wezinso Othuthukile: Uma umdlavuza wezinso ususakazekele kwezinye izingxenye zomzimba.
- Ama-Pancreatic Neuroendocrine Tumors: Lolu futhi uhlobo olukhethekile lomdlavuza oluvela kuma-pancreas.
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuqala imithi
Ngaphambi kokuqala i-Sunitinib, kubaluleke kakhulu ukutshela udokotela wakho ngomlando wakho wezempilo ophelele. Lokhu kungenxa yokuthi lo muthi ungase uhlangane nezimo ezithile zezokwelapha. Bheka ithebula elingezansi. Uma unezinye zalezi zimo, qiniseka ukuthi utshela udokotela wakho.
| Isimo okudingeka usibike | Kungani kunjalo? (Isizathu okufanele udokotela azi) |
|---|---|
| Izinkinga zokopha noma ukuklwebheka kalula | Lo muthi ungandisa ingozi yokopha. |
| Izinkinga zamazinyo, uma usebenzisa amazinyo okufakelwa | Ukwelashwa kwamazinyo kufanele kuhlelwe kusenesikhathi, njengoba imithi ingathinta umhlathi. |
| Isifo sikashukela | Amazinga kashukela egazini angase athinteke. |
| Uma uzohlinzwa maduze | Ngenxa yokuthi ithinta ukuphulukiswa kwenxeba, umuthi kumele uyekwe ngaphambi nangemva kokuhlinzwa. |
| Isifo senhliziyo, umfutho wegazi ophakeme, ukuphazamiseka kwesigqi senhliziyo | Umuthi ungathinta ukusebenza kwenhliziyo kanye nomfutho wegazi. |
| Izinso (ngaphandle komdlavuza) noma isifo sesibindi | Umsebenzi walezi zitho uthinta umphumela womuthi. |
| Isifo se-thyroid | Umuthi ungathinta amazinga e-hormone ye-thyroid. |
| Uma ukhulelwe, uzama ukukhulelwa, noma uncelisa | Lokhu kubaluleke kakhulu! Lo muthi ungabangela umonakalo omkhulu enganeni esibelethweni. |
| Ukungezwani komzimba ne-Sunitinib noma eminye imithi noma ukudla | Kubalulekile ukwazisa lokhu ukuze ugweme ukusabela kokungezwani komzimba. |
Uyisebenzisa kanjani le mithi?
Indlela yokusebenzisa lokhu ilula kakhulu, kodwa ibaluleke kakhulu.
- Gwinya umuthi wonke ngengilazi yamanzi.
- Ungayithatha ngaphambi noma ngemva kokudla. Ngeke kube yinkinga.
- Into ebaluleke kakhulu ukuthatha umuthi njengoba nje udokotela ewushilo, ngesikhathi osishilo.
- Ungalokothi, nganoma yisiphi isizathu, uyeke ukuthatha imithi noma ushintshe umthamo ngaphandle kweseluleko sikadokotela wakho.
Yini okufanele uyenze uma uphuthelwa umthamo wemithi?
Uma uphuthelwa umthamo, thatha ngokushesha nje lapho ukhumbula. Kodwa-ke, uma kungaphansi kwamahora ayi-12 ngaphambi komthamo wakho olandelayo, yeqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esihleliwe. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa.
Kuthiwani uma ngiphuza umuthi omningi kakhulu?
Uma ucabanga ukuthi uthathe umuthi omningi kunalokho okucabangayo, ungesabi futhi ngokushesha uye eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela esiseduze. Noma shayela i-National Poisons Information Centre e-Colombo National Hospital .
Ezinye izinto ezingase zihlangane ne-Sunitinib
Lokhu kubaluleke kakhulu futhi. Uma uthatha i-Sunitinib, kubalulekile ukutshela udokotela wakho ngayo yonke imithi oyithathayo (kufaka phakathi imithi yezinye izimo, amavithamini, imithi yendabuko, imikhiqizo yamakhambi). Eminye imithi ingasebenzisana ne-Sunitinib futhi inciphise imiphumela yayo, yandise imiphumela yayo, noma ibangele imiphumela emibi eyingozi.
Qaphela kakhulu okulandelayo:
- Eminye imithi ye-HIV noma i-hepatitis
- Imithi yokutheleleka kwesikhunta (isb. i-ketoconazole, i-itraconazole)
- Amanye ama-antibiotic (isb. i-clarithromycin)
- Eminye imithi yokwelapha ukuxhuzula (isib. i-carbamazepine, i-phenytoin)
- Umkhiqizo wezitshalo i-St. John's Wort
- Eminye imithi enweba isikhathi sokuphumula kwe-QT
- Ijusi le-grapefruit: Lokhu kuyinto abantu abaningi abangazi. Ukuphuza ijusi le-grapefruit kungathinta indlela i-Sunitinib esebenza ngayo. Ngakho-ke, gwema ngokuphelele ijusi le-grapefruit kanye ne-grapefruit ngenkathi uthatha lo muthi.
Amaphuzu akhethekile okufanele uwaqaphele lapho uthatha umuthi
Amazinyo kanye nempilo yomlomo
Lo muthi ngezinye izikhathi ungathinta umhlathi (i-Osteonecrosis yomhlathi). Ngakho-ke, kungcono ukubona udokotela wamazinyo ngaphambi kokuqala umuthi bese uxazulula noma yiziphi izinkinga zamazinyo. Futhi, tshela udokotela wamazinyo ukuthi uthatha lo muthi. Kuwukuhlakanipha ukugwema ukuhlinzwa okukhulu kwamazinyo ngenkathi uthatha umuthi.
Ukuhlinzwa kanye nokuphulukiswa kwamanxeba
I-Sunitinib ingase inciphise inqubo yokuphulukiswa kwamanxeba. Uma uzohlinzwa, tshela udokotela wakho womdlavuza. Ngokuvamile kunconywa ukuthi uyeke ukuthatha umuthi amasonto ama-3 ngaphambi kokuhlinzwa bese uwuqala kabusha ngemva kokuba inxeba selipholile kahle (okungenani amasonto ama-2 ngemva kokuhlinzwa).
Ukukhulelwa, ukubeletha kanye nokuncelisa
Lokhu kubaluleke kakhulu!Uma ungowesifazane, gwema ukukhulelwa ngokuphelele ngenkathi uthatha lo muthi futhi okungenani amasonto amane ngemva kokuyeka umuthi. Uma ungowesilisa, gwema ukukhulelwa ngenkathi uthatha umuthi futhi okungenani amasonto ayi-7 ngemva kokuyeka umuthi.
Lo muthi ungabangela umonakalo omkhulu enganeni engakazalwa. Ngakho-ke, kubalulekile ukusebenzisa uhlobo oluthembekile lokuvimbela inzalo phakathi nalesi sikhathi. Futhi, gwema ukuncelisa ngenkathi uthatha lo muthi kanye namasonto ama-4 ngemva kokuyeka.
Yimiphi imiphumela emibi engaba khona?
Njenganoma yimuphi umuthi, i-Sunitinib ingaba nemiphumela emibi. Kodwa-ke, akuwona wonke umuntu oyitholayo. Into ebaluleke kakhulu ukuqaphela lokhu nokwazisa udokotela wakho ngokushesha uma uhlangabezana nanoma yiziphi izinkinga.
| Imiphumela emibi okufanele ibikwe kudokotela wakho noma esibhedlela ngokushesha | |
|---|---|
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe, ulimi |
| Ubunzima bokuphefumula, ubuhlungu besifuba | Inhliziyo noma amaphaphu kungathinteka. |
| Ubuhlungu obukhulu besisu, ukopha okungavamile noma ukuminyana | Kungaba uphawu lokopha kwangaphakathi. |
| Ukuvuvukala kwemilenze, amaqakala, ukukhuluphala ngokuzumayo | Kungaba nenkinga yenhliziyo noma yezinso. |
| Ubuhlungu bomhlathi (ikakhulukazi ngemva kokukhishwa kwezinyo) | Kungaba nomthelela ethanjeni lomhlathi. |
| Ukubomvu, ukuqhakaza, kanye nokuqhekeka kwesikhumba | Isibonakaliso sokusabela okukhulu kwesikhumba. |
| Umfutho wegazi ophakeme, ikhanda elibuhlungu, ukuquleka | Umphumela ohlelweni lwezinzwa noma umfutho wegazi. |
| Tshela udokotela wakho uma kuqhubeka noma kuyakhathaza. | |
| Uhudo | Ukuqunjelwa. |
| Isicanucanu nokuhlanza | Isicanucanu nokuhlanza. |
| Izilonda zomlomo | Izilonda emlonyeni. |
| Izinguquko zesikhumba | Ukuphuzi kwesikhumba, ukoma, ukuqhekeka, kanye nobuhlungu besikhumba ezintendeni nasematheni. |
| Ukushintsha kombala wezinwele | Umbala wezinwele okhanyayo. |
| Ukukhathala | Ukuzizwa ukhathele ngendlela engavamile. |
| Ukulahlekelwa yisifiso sokudla kanye nezinguquko ekunambithekeni | Ukuncipha kwesifiso sokudla kanye nokushintsha kokunambitheka kokudla. |
Umlayezo Wokuya Nawe Ekhaya
- I-Sunitinib umuthi okhethekile ohlasela amangqamuzana omdlavuza.
- Landela imiyalelo kadokotela wakho ngqo. Ungalokothi uyeke ukuthatha umuthi noma ushintshe umthamo ngokwakho.
- Tshela udokotela wakho ngayo yonke eminye imithi, imikhiqizo yamakhambi, kanye nejusi yamagilebhisi oyiphuzayo.
- Gwema ukukhulelwa nokuncelisa ngokuphelele ngenkathi uthatha imithi futhi uma nje udokotela wakho ekuyala. Ukusebenzisa izindlela zokuvimbela inzalo ezithembekile kubalulekile.
- Uma uhlangabezana nanoma yimiphi imiphumela emibi efana nobunzima bokuphefumula, ukopha okungavamile, noma ukuvuvukala komzimba, shesha uye kudokotela wakho noma eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela esiseduze.
- Khuluma nodokotela wakho nganoma yimiphi imibuzo noma ukukhathazeka ongase ube nakho. Bahlala bekulungele ukukusiza.
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