Nawe uke wafakelwa isitho, njengesinso, isibindi, noma inhliziyo, futhi udokotela wakunikeza umuthi okhethekile wokuvimbela isitho esisha ukuba singalahlwa ngumzimba wakho. Isikhathi esiningi, lowo muthi ubizwa ngokuthi i-Tacrolimus. Lo umuthi obaluleke kakhulu, futhi umuthi odinga ukusetshenziswa ngokucophelela. Ngakho-ke, njengomngane wakho, ngilapha ukuzokutshela konke okudingeka ukwazi ngalo muthi ngolimi olulula noluqondakalayo lwesiSinhala.
Kalula nje, iyini iTacrolimus?
Cabanga ngesimiso somzimba wethu sokuzivikela njengebutho elivikela izwe. Leli butho libhubhisa izitha ezifana namagciwane namagciwane avela ngaphandle. Manje, uma uthola ukufakelwa isitho esisha, leli "butho" emzimbeni wethu libona leso sitho esisha "njengesitha." Ngoba kuyinto entsha emzimbeni. Ngakho leli butho liqala ukuhlasela isitho esisha. Yilokhu esikubiza ngokuthi "ukwenqatshwa kwesitho."
I- Tacrolimus umuthi othulisa umsebenzi walelo "butho." Kwezokwelapha, sibiza lawa ma-immunosuppressants . Kalula nje, lo muthi utshela amasosha omzimba wethu ukuthi, "Ungakhathazeki, lesi sitho esisha singumngane wethu, ungasihlaseli." Ngakho isitho esisanda kutshalwa siqala ukusebenza njengengxenye yomzimba wakho ngaphandle kwezinkinga.
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuqala lo muthi
Kubaluleke kakhulu ukuthi udokotela wakho azi kahle isimo sakho sempilo ngaphambi kokukunikeza lo muthi. Ngakho-ke, uma unezinye zezimo ezibalwe ngezansi, qiniseka ukuthi uyamtshela udokotela wakho.
- Uma unesifo sikashukela .
- Uma unesifo senhliziyo .
- Uma une -high blood pressure .
- Uma kukhona enye inkinga ngesimiso somzimba sokuzivikela.
- Uma unesifo esikhona kakade (ngisho nento efana nomkhuhlane, umkhuhlane, ukukhwehlela).
- Uma unesifo sezinso .
- Uma unesifo sesibindi .
- Uma uhlelelwe ukuthola umuthi wokugoma esikhathini esizayo noma usanda kuwuthola.
- Uma uke waba nokusabela kokungezwani komzimba ne-tacrolimus noma yimuphi omunye umuthi, ukudla, noma idayi.
- Uma uzama ukukhulelwa noma ukhulelwe .
- Uma ungumama oncelisayo .
Kubaluleke kakhulu ukuze uphephe ukusho lezi zinto ngaphandle kokuzifihla.
Iyiphi indlela efanele yokusebenzisa umuthi?
Ukuze uthole okuningi kulo muthi, udinga ukuwuthatha njengoba nje kuqondiswe.
- Gwinya umuthi wonke ngengilazi yamanzi.
- Ungawuthathi lo muthi kanye nejusi le-grapefruit noma le-grapefruit nganoma yisiphi isizathu. Lokhu kubaluleke kakhulu. Ijusi le-grapefruit lingabangela amazinga aphezulu e-Tacrolimus emzimbeni.
- Zijwayeze ukuphuza imithi yakho ngesikhathi esifanayo nsuku zonke. Uma kungu-8 ekuseni, yithathe ngo-8 ekuseni nsuku zonke. Lokhu kuzosiza ukugcina amazinga omuthi emzimbeni wakho engaguquguquki.
- Ungawuphuli, ungawuchobozi, noma uwuhlafune umuthi. Wugwinye wonke.
- Ungawuthatha lo muthi ngaphambi noma ngemva kokudla. Kodwa-ke, kufanele ube nomkhuba wokuwuthatha ngesikhathi esifanayo nsuku zonke. Uma uwuthatha ngaphambi kokudla, uwuthathe nsuku zonke ngaphambi kokudla. Uma uwuthatha ngemva kokudla, uwuthathe nsuku zonke ngemva kokudla.
- Qhubeka usebenzisa lo muthi kuze kube yilapho udokotela wakho ekutshela ukuthi uyeke. Ungayeki ngokuzumayo.
Khumbula, lo muthi unikezwe wena wedwa. Ungalokothi unike omunye umuntu umuthi wakho, noma ngabe unezimpawu ezifanayo nezakho.
Yini okufanele uyenze uma uthatha umuthi omningi kakhulu?
Uma ucabanga ukuthi uthathe imithi eminingi kunesilinganiso esinqunyiwe, ungesabi futhi uthathe isinyathelo ngokushesha.
- Uma kungenzeka, hamba uye eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela esiseduze ngokushesha.
- Ngaphandle kwalokho, shayela iNational Poison Information Centre eColombo National Hospital ukuze uthole iseluleko.
Kuthiwani uma ngikhohlwa ukuphuza umuthi wami?
Sonke siyakhohlwa izinto. Uma ukhohlwa ukuphuza imithi yakho, nakhu okufanele ukwenze:
- Thatha umthamo ophuthelwe ngokushesha nje lapho ukhumbula.
- Kodwa-ke, uma sekuyisikhathi somthamo wakho olandelayo uma ukhumbula (isb., kusele amahora ambalwa nje), yeqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esihleliwe.
- Ungalokothi uthathe umthamo ophindwe kabili ukuze ubuyisele umthamo ongawutholanga kanye nomthamo olandelayo.
Eminye imithi engase ihlangane ne-Tacrolimus
I-Tacrolimus ingasebenzisana neminye imithi eminingi. Ngakho-ke, tshela udokotela wakho ngayo yonke imithi oyithathayo (imithi kadokotela, imithi yokwelapha izinhlungu ethengiswa ngaphandle kwemithi kadokotela, amavithamini, imithi yamakhambi, kanye nezithasiselo zamakhambi, njenge-St. John's wort). Ungathola ulwazi olwengeziwe ngalokhu kuthebula elingezansi.
| Uhlobo lomuthi/lokudla | Amanothi akhethekile |
|---|---|
| Ungalokothi uthathe lezi ne-Tacrolimus! | |
| I-Grapefruit kanye nojusi wayo | Kukhuphula izinga le-Tacrolimus emzimbeni ngendlela eyingozi. |
| I-Cyclosporine | Ukuthatha le mithi emibili ndawonye kungalimaza izinso. |
| Imithi yokugomela igciwane ephilayo | Ngenxa yokuzivikela komzimba okuphansi, umuthi wokugoma ungabangela ukugula. |
| Imithi efana ne-Fluconazole, i-Ketoconazole, i-Cidofovir, i-Dronedarone, ne-Pimozide | Lokhu kungathinta kakhulu amazinga e-Tacrolimus. |
| Uma uthatha lezi, qiniseka ukuthi utshela udokotela wakho. | |
| Amanye ama-antibiotic | Isibonelo: i-Clarithromycin, i-Rifampin |
| Imithi yokucindezeleka kwegazi nesifo senhliziyo | Isibonelo: i-Diltiazem, i-Enalapril, i-Losartan |
| Imithi yokulwa nesikhunta | Isibonelo: i-Itraconazole, i-Voriconazole |
| I-wort kaSt. John | Lokhu kunciphisa ukusebenza kahle kwe-Tacrolimus. |
| Ama-antiviral e-HIV noma i-Hepatitis | Lokhu kungathinta amazinga e-Tacrolimus. |
Izinto okufanele uziqaphele kakhulu lapho uthatha lo muthi:
Kuzodingeka wenze izinguquko ezincane endleleni yakho yokuphila ngenkathi uthatha i-tacrolimus. Lezi zibaluleke kakhulu ekuphepheni kwakho.
Ukuhlolwa kwezokwelapha okuhleliwe
Udokotela wakho kuzodingeka akubone njalo. Uzophinde aku-ode ukuhlolwa kwegazi njalo ukuze ahlole amazinga akho e-Tacrolimus kanye nokusebenza kwezinso. Ungalokothi uphuthelwe yilokhu kuhlolwa kwegazi.
Zivikele ezifweni
Ngenxa yokuthi lo muthi unciphisa ukusebenza kwesimiso sakho somzimba, kungenzeka kakhulu ukuthi ube nezifo, ikakhulukazi izifo.
- Nciphisa ukuya ezindaweni ezinabantu abaningi ngangokunokwenzeka.
- Hlala kude nabantu abanezifo ezifana nomkhuhlane kanye nomkhuhlane.
- Geza izandla zakho njalo ngensipho.
- Uma uba nezimpawu zokutheleleka njengomkhuhlane, ukubanda, umphimbo obuhlungu, ukukhwehlela, noma ukushisa lapho uchama, ungaziniki imithi bese ushayela udokotela wakho ucingo ngokushesha.
Ukukhulelwa kanye nokulawula ukubeletha
- Abesifazane: Ukukhulelwa ngenkathi uthatha lo muthi kungabangela izinkinga ezinkulu zokuzalwa enganeni. Ngakho-ke, kubalulekile ukusebenzisa izindlela zokuvimbela inzalo ezithembekile ngaphambi kokuqala umuthi naphakathi nesikhathi sonke osithathayo. Khuluma nodokotela wakho ngalokhu.
- Amadoda: Uma uthatha lo muthi, kubalulekile ukusebenzisa ikhondomu ngesikhathi socansi. Uma umlingani wakho ekhulelwa, yazisa udokotela wakho ngokushesha.
Qaphela ilanga.
I-Tacrolimus ingenza isikhumba sakho sizwele kakhulu elangeni futhi ingandisa kancane ingozi yakho yomdlavuza wesikhumba.
- Gwema ukuphuma elangeni ngangokunokwenzeka.
- Uma uphuma elangeni, gqoka izingubo ezinemikhono emide, isigqoko, bese usebenzisa umuthi omuhle wokuvikela ilanga .
Izinga likashukela egazini
Lo muthi ungabangela amazinga aphezulu kashukela egazini (i-hyperglycemia) . Le ngozi iphezulu kakhulu uma unesifo sikashukela. Qaphela izimpawu ezinjengokoma njalo, ukuchama njalo, kanye nokungaboni kahle.
Imiphumela emibi engase ivele ngenxa yemithi
Njenganoma yimuphi umuthi, i-Tacrolimus ingabangela imiphumela emibi. Eminye iyingozi, kanti eminye incane. Into ebalulekile ukuqaphela lezi zimpawu bese uthatha isinyathelo ngokushesha uma kudingeka.
| Izimpawu zemiphumela emibi | Incazelo nokuthi yini okufanele uyenze |
|---|---|
| Uma uhlangabezana nalezi zimpawu, tshela udokotela wakho ngokushesha! | |
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe, ulimi noma umphimbo. |
| Izimpawu zokutheleleka | Umkhuhlane, ukubanda, umphimbo obuhlungu, amanxeba angapholi. |
| Ukulimala kwezinso | Ukwehla kokukhishwa komchamo, ukuvuvukala kwamaqakala, izandla, noma izinyawo. |
| Umfutho wegazi okhuphukile | Ikhanda elibuhlungu kakhulu, isiyezi. |
| Ukwanda koshukela egazini (i-Hyperglycemia) | Ukoma ngokweqile, ukuchama njalo, ukukhathala okukhulu, ukubona okufiphele. |
| Izinguquko ekushayeni kwenhliziyo | Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile, isiyezi, ubuhlungu besifuba. |
| Izinkinga zesistimu yezinzwa (PRES) | Ikhanda elibuhlungu kakhulu ngokuzumayo, ukudideka, ukushintsha kombono, nokuxhuzula. |
| Imiphumela kumaseli egazi (TTP/HUS) | Amabala ansomi esikhumbeni noma ngaphakathi emlonyeni, isikhumba esikhanyayo, ukuphuzi kwamehlo, ukukhathala okukhulu, umkhuhlane. |
| Lokhu ngokuvamile akukubi kangako, kodwa uma kuqhubeka, tshela udokotela wakho. | |
| Uhudo noma ukuqunjelwa | Lokhu kuvame ukuphela phakathi nezinsuku ezimbalwa. |
| Ukuthuthumela | Ungase uzwe ukuthuthumela, ikakhulukazi ezandleni. |
| Inkinga yokulala | Kungase kube nobunzima bokulala. |
| Ukuba ndikindiki noma ubuhlungu ezithweni | Ungase uzwe umuzwa wokucasuka ezandleni nasezinyaweni zakho. |
Uyigcina futhi uyilahle kanjani imithi ngendlela efanele?
- Gcina umuthi kude nezingane nezilwane ezifuywayo .
- Gcina endaweni yokushisa evamile yegumbi (phakathi kwama-degree Celsius angu-20-25). Ungagcini ezindaweni ezinomswakama ophezulu njengasegumbini lokugezela.
- Ungasebenzisi umuthi ophelelwe yisikhathi.
- Ukuze ulahle imithi engasetshenziswanga noma ephelelwe yisikhathi, kungcono ukuyidlulisela esibhedlela noma ekhemisi. Uma lokho kungenzeki, susa ama-capsule emithi esitsheni, uwaxube nento efana nekhofi eligayiwe, inhlabathi, noma udoti wekati osetshenzisiwe, uwafake esikhwameni esivalwe kahle, bese uwaphonsa emgqonyeni kadoti.
Umlayezo Wokuya Nawe Ekhaya
- I-Tacrolimus umuthi obaluleke kakhulu ovikela isitho sakho esisha. Yiphuze njengoba nje udokotela wakho ekutshelile, ngesikhathi esifanele, ngomthamo ofanele.
- Ungawuthathi lo muthi kanye nejusi lamagilebhisi nganoma yisiphi isizathu.
- Yazisa udokotela wakho ngayo yonke eminye imithi oyithathayo (kufaka phakathi amavithamini kanye nemithi ye-Ayurvedic).
- Njengoba amasosha akho omzimba ephansi, zivikele ezifweni. Uma uba nezimpawu ezifana nomkhuhlane nokukhwehlela, tshela udokotela wakho ngokushesha.
- Qaphela izimpawu zemiphumela emibi kakhulu (ikhanda elibuhlungu kakhulu, ukuvuvukala, ubunzima bokuphefumula). Uma ucabanga ukuthi kukhona okungahambi kahle, shayela udokotela wakho.
- Kuphoqelekile ukuya emihlanganweni kadokotela kanye nokuhlolwa kwegazi ngezinsuku ezihleliwe.
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