Uma unesifo sikashukela sohlobo lwesibili, udokotela wakho kungenzeka ukuthi ukunike umuthi obizwa ngokuthi i-Canagliflozin (ngokuvamile owaziwa ngokuthi i-Invokana ezweni lakithi) ukusiza ukulawula amazinga kashukela egazini lakho. Lo muthi usebenza kahle kakhulu uma usetshenziswa kanye nokudla okunempilo kanye nokuzivocavoca kwansuku zonke. Ngakho-ke, ake sixoxe ngezinye zezinto ezibaluleke kakhulu okudingeka uzazi ngalo muthi.
1. Yiziphi izimo ezelapha iCanagliflozin?
Isifo sikashukela nesifo senhliziyo kuvame ukuhambisana. Eqinisweni, ucwaningo luthole ukuthi abantu abanesifo sikashukela banamathuba aphindwe kabili okuthola isifo senhliziyo noma ukwehluleka kwenhliziyo kunabantu abangenaso isifo sikashukela.
I-Canagliflozin ingeyesigaba semithi ebizwa ngokuthi i-sodium-glucose co-transporter 2 (SGLT2) inhibitors. Kalula nje, isebenza ngokunciphisa inani likashukela elikhishwa ngumzimba wakho emchameni wakho, okwehlisa amazinga kashukela egazini lakho.
Enye inzuzo ekhethekile yalokhu ukuthi lo muthi uvunyelwe ukunciphisa ingozi yokufa ngenxa yezimo ezimbi njengokuhlaselwa yinhliziyo kanye nohlangothi kubantu abadala abanesifo sikashukela sohlobo lwesibili abanesifo senhliziyo, noma abasengozini enkulu yokuthola izifo ezinjalo.
Ngaphezu kwalokho, lo muthi usiza ekunciphiseni izici ezilandelayo eziyingozi:
- Isifo sezinso sesigaba sokugcina
- Ukusebenza kwezinso okungasebenzi kahle
- Ukulaliswa esibhedlela ngenxa yokwehluleka kwenhliziyo
- Ukulaliswa esibhedlela ngenxa yokulimala kwezinso okubangelwa isifo sikashukela (Diabetic Nephropathy)
Okubaluleke kakhulu, lo muthi awufanele abantu abanesifo sikashukela sohlobo 1. Futhi, abantu abanesifo sezinso esibi kakhulu abakwazi ukuwuthatha lo muthi.
2. Ungayisebenzisa kanjani le mithi?
Lona umuthi oza ngesimo sephilisi. Kufanele uwuthathe kanye ngosuku, ngokuvamile ngaphambi kokudla kwakho kokuqala kosuku.
Lo muthi ungathathwa neminye imithi yesifo sikashukela, njenge-metformin. Kodwa-ke, ngezinye izikhathi le mithi ingasebenzisana. Uma lokhu kwenzeka, ukusebenza kwayo kungancipha noma imiphumela emibi ingase ivele. Ngakho-ke, kubalulekile ukutshela udokotela wakho ngayo yonke imithi, amavithamini, kanye nezithasiselo zokudla ozithathayo.
Udokotela wakho uzolungisa umthamo uma kudingeka. Gcina lo muthi ezingeni lokushisa legumbi, esitsheni esivaliwe. Gcina kude nokushisa okukhulu, umswakama, kanye nokukhanya kwelanga okuqondile. Lahla umuthi ophelelwe yisikhathi ngokuphephile.
Unjani umthamo wemithi?
Udokotela wakho cishe uzokuqala ngephilisi elingu-100 milligram (100mg). Uma udinga ukulawula okwengeziwe amazinga kashukela egazini lakho, umthamo wakho ungase ukhuphuke ube ngu-300 milligram (300mg) ngosuku. Uma uphuthelwa umthamo, thatha ngokushesha nje lapho ukhumbula. Kodwa uma sekuyisikhathi somthamo wakho olandelayo, ungathathi imithamo emibili ngesikhathi esisodwa. Yeqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo njengokujwayelekile.
3. Yimiphi imiphumela emibi engaba khona?
Abanye abantu bangase babe nemiphumela emibi emnene, ephakathi nendawo, noma enzima evela kulo muthi. Masiqaphele.
| Uhlobo lomphumela ongemuhle | Izici okufanele uziqaphele |
|---|---|
| Imiphumela emibi evame ukubonwa | |
| Izifo Zomgudu Womchamo | Ukusha lapho uchama, ubuhlungu besisu esingezansi, isidingo sokuchama njalo, igazi emchameni. |
| Ushukela ophansi egazini (i-Hypoglycemia) | Lokhu kungenzeka uma kuthathwa neminye imithi yesifo sikashukela. Izimpawu zifaka phakathi isiyezi, ikhanda elibuhlungu, ukujuluka, ukuthuthumela, kanye nokushaya kwenhliziyo okusheshayo. |
| Imiphumela emibi kakhulu/esheshayo yokufuna ukunakekelwa kwezokwelapha | |
| Ukutheleleka okungavamile kwebhaktheriya (Necrotizing Fasciitis) | Ukutheleleka okuyingozi okubhubhisa izicubu ezingaphansi kwesikhumba ezizungeze indawo yangasese kanye ne-anus. Funa iseluleko sezokwelapha ngokushesha uma uhlangabezana nezimpawu ezifana nobuhlungu, ukuvuvukala, kanye nokubomvu. |
| Ukusabela okukhulu kokungezwani komzimba | Ukuqubuka kwesikhumba, ukuvuvukala, amaqhubu, noma ukulunywa okukhulu. Lezi futhi yizimo ezidinga ukunakekelwa kwezokwelapha okusheshayo . |
| Ukuphuka Kwamathambo | Ucwaningo lukhombisile ukuthi lo muthi ungandisa kancane ingozi yokuqhekeka kwamathambo. |
| Ezinye izimpawu ezinzima | Ukulahlekelwa umbono, ukubona okufiphele, ubuhlungu bamehlo, ubunzima bokuphefumula, ukushaya kwenhliziyo okungajwayelekile, ukuquleka, ubunzima bokukhuluma, ubunzima bokuhamba, ukujuluka ngokweqile, noma umkhuhlane. |
Uma uhlangabezana nanoma yimiphi yale miphumela emibi kakhulu , ungalibali bese ushayela ucingo ngokushesha kwi-ambulensi ka-1990 noma uye e-Emergency Treatment Unit (ETU) yesibhedlela esiseduze.
4. Izixwayiso ezikhethekile kanye nokuphepha (Izixwayiso)
Ingozi yokususwa kwezinyawo
Kukhona impikiswano mayelana nokuthi lo muthi uyayandisa yini ingozi yokunqunywa kwezitho zomzimba, ikakhulukazi izinyawo nemilenze engezansi. Lokhu akuvamile neze. Kodwa-ke, uma uke wahlinzwa kanjalo ngaphambili, noma uma unezilonda noma izifo ezinyaweni njalo, kubalulekile ukuqaphela lokhu futhi unakekele izinyawo zakho ngokukhethekile.
Isimo se-ketoacidosis yesifo sikashukela (i-DKA)
Lokhu kuyinto ebaluleke kakhulu okufanele uyazi ngalo muthi. Lo muthi ungabangela isimo esiyingozi kakhulu esibizwa ngokuthi i-Diabetic Ketoacidosis (DKA) kwabanye abantu abanesifo sikashukela sohlobo lwesibili.
Kalula nje, i-DKA yenzeka lapho umzimba wakho ungenayo i-insulin eyanele yokuguqula ushukela egazini lakho ube amandla. Umzimba wakho bese uqala ukushisa amafutha ukuze uthole amandla. Phakathi nale nqubo, amakhemikhali abizwa ngokuthi ama-ketone ayanda egazini lakho. Lapho la ma-ketone eyanda ngokweqile, igazi lakho liba ne-asidi, okungaba ubuthi emzimbeni wakho futhi kukwenze ugule kakhulu. Ezimweni ezimbi kakhulu, ungangena kwi-coma yesifo sikashukela noma ngisho nokufa.
Izimpawu zokuqala ze-DKA ukoma ngokweqile kanye nokuchama njalo. Lesi yisibonakaliso esiyisixwayiso sokuthi isifo sakho sikashukela asisalawuleki. Khuluma nodokotela wakho mayelana nendlela yokuvimbela i-DKA futhi ugcine amazinga akho e-insulin kanye noshukela egazini esezingeni elifanele.
5. Yiziphi izinyathelo zokuphepha okufanele zithathwe ngaphambi kokuhlinzwa?
Yebo. Uma unokuhlinzwa okuhleliwe, kufanele uyeke ukuthatha lo muthi ezinsukwini ezi-3 ngaphambi kokuhlinzwa ukuze unciphise ingozi ye-DKA. Kubalulekile ukwazisa udokotela wakho ohlinzayo kanye nodokotela wakho wesifo sikashukela ngalokhu. Phakathi nalesi sikhathi, udokotela wakho uzoqapha amazinga kashukela egazini lakho futhi asebenzise ezinye izindlela ukuwalawula.
6. Ubani okungafanele asebenzise i-Canagliflozin?
Odokotela abawuncomi lo muthi uma unezimo ezilandelayo:
- Uma unesifo sesibindi esibi kakhulu
- Uma ukhulelwe noma unethemba lokukhulelwa
- Uma ungumama oncelisayo
- Uma ungaphansi kweminyaka eyi-18 ubudala
- Uma uke waba nokusabela okukhulu kokungezwani komzimba (isb., i-anaphylaxis noma ukuvuvukala okufana ne-angioedema) kulo muthi
- Uma usebenzisa i-dialysis yezinso
Ngaphambi kokusebenzisa lo muthi, kubaluleke kakhulu ukukhuluma nodokotela wakho ukuqinisekisa ukuthi lo muthi ulungele wena ukulawula isifo sikashukela sakho.
Umlayezo Wokuya Nawe Ekhaya
- I-Canagliflozin umuthi osetshenziselwa ukwelapha isifo sikashukela sohlobo 2. Futhi iyasiza ekunciphiseni ingozi yesifo senhliziyo nesifo sezinso.
- Leli philisi kufanele lithathwe kanye ngosuku, ngaphambi kokudla kokuqala.
- Ungakhohlwa ukutshela udokotela wakho ngayo yonke eminye imithi oyithathayo.
- Qaphela imiphumela emibi efana nokutheleleka komgudu womchamo, ushukela ophansi egazini (i-hypoglycemia), kanye nokutheleleka okungavamile kwezitho zangasese.
- Qaphela izimpawu zesimo esiyingozi esibizwa ngokuthi i-Diabetic Ketoacidosis (DKA) (ukoma ngokweqile, ukuchama njalo).
- Lo muthi kufanele uyekwe ezinsukwini ezi-3 ngaphambi kwanoma yikuphi ukuhlinzwa, njengoba kuqondiswe udokotela wakho.
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