Siyazi ukuthi kunzima kangakanani ukulwa nomdlavuza. Kuvamile ukuzizwa ukhungathekile lapho odokotela besho amagama amasha nayinkimbinkimbi njengokuthi "ukwelashwa ngezakhi zofuzo." Kodwa ungakhathazeki. Namuhla sizokhuluma ngenye yokwelashwa okunjalo. Cabanga usebenzisa amangqamuzana omzimba wakho, uwaqeqesha, futhi uwathumela ukubhubhisa amangqamuzana omdlavuza. Yilokho okwenziwa yilolu hlobo lokwelashwa olubizwa ngokuthi iTisagenlecleucel. Ake sixoxe ngakho kalula nangokucacile.
Kuyini i-Tisagenlecleucel (KYMRIAH)?
Kalula nje, leli akulona iphilisi oliphuzayo noma umuthi ojwayelekile owufaka emthanjeni. I-Tisagenlecleucel iyindlela yokwelapha izakhi zofuzo . Kuhilela ukuthatha uhlobo lweseli ohlelweni lwakho lokuzivikela komzimba, ukulushintsha elabhorethri, nokuluqeqesha ukuthi lubone futhi luhlasele amangqamuzana omdlavuza.
Ukuze kube sobala, imizimba yethu inohlobo lweseli lokulwa elibizwa ngokuthi ama-T-cell. Lawa maseli yiwo alwa nezifo. Kulokhu kwelashwa, odokotela bathatha amanye ala ma-T-cell emzimbeni wakho. Bese, elabhorethri, basebenzisa ubuchwepheshe bezakhi zofuzo ukufaka "izibuko ezimbili ezikhethekile" kula ma-T-cell. Okusho ukuthi, baguqula lawa maseli ukuze akwazi ukubona izimpawu ezithile ebusweni bamaseli omdlavuza. Bese, izigidi zala ma-T-cell "anamandla amakhulu" ziyakhuliswa bese zifakwa emzimbeni wakho ngomthambo. Manje lawa maseli aqeqeshwe aya ngqo kumaseli omdlavuza futhi awabhubhise.
Lokhu kwelashwa kusetshenziselwa kakhulu ukwelapha izinhlobo eziningana zomdlavuza, okuhlanganisa i-acute lymphoblastic leukemia (ALL) , uhlobo lwe-leukemia, kanye ne-non-Hodgkin lymphoma .
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuqala ukwelashwa
Ngisho noma lokhu kuyindlela yokwelapha esebenzisa amaseli akho, kubalulekile ukuba nengxoxo evulekile nethimba lakho lokunakekela ngaphambi kokuba uqale. Kufanele baziswe ngalokhu okulandelayo:
- Ukutheleleka Kwamanje: Sitshele uma okwamanje unezifo ezithathelwanayo, njengomkhuhlane, ukukhwehlela, umkhuhlane, noma ukutheleleka komgudu womchamo.
- Izimo zokuvuvukala: Tshela udokotela wakho nganoma yiziphi izifo zokuvuvukala noma kuphi emzimbeni.
- Ukungezwani komzimba: Qiniseka ukuthi ukhuluma nganoma yikuphi ukungezwani komzimba onakho, hhayi nje kulo muthi, kodwa nanoma yimuphi omunye umuthi, ukudla, noma udayi.
- Ukukhulelwa: Uma ukhulelwe, uzama ukukhulelwa, noma usola ukuthi ukhulelwe, tshela udokotela wakho ngokushesha. Lokhu kubaluleke kakhulu.
- Ukuncelisa: Uma uncelisa, yazisa nodokotela.
Ukunikeza kanjani lokhu kwelashwa?
Lokhu kwelashwa kuhilela izinyathelo eziningana futhi kwenziwa ngaphansi kokuqashwa okuseduze kwethimba lezokwelapha esibhedlela noma emtholampilo okhethekile.
1. Ukuqoqwa kwamaseli: Cishe emavikini ama-3-4 ngaphambi kokwelashwa, amaseli e-T aqoqwa emzimbeni wakho. Lokhu kwenziwa ngenqubo ebizwa ngokuthi i-leukapheresis . Kufana nokunikela ngegazi. Igazi lithathwa emthanjeni, lidluliselwe ngomshini okhethekile, ohlukanisa amaseli egazi amhlophe, okuhlanganisa namaseli e-T, bese igazi elisele libuyiselwa emzimbeni wakho.
2. Ukuqeqeshwa kwamaseli: Lawa maseli aqoqiwe abe esethunyelwa elabhorethri futhi aqeqeshwe ukulwa nomdlavuza.
3. Ukumnika: Uma amaseli eseqeqeshwa futhi ekhulile, afakwa emzimbeni wakho ngemithambo yegazi, njengesixazululo sikasawoti. Lonke lolu hlelo lwenzeka esibhedlela.
Into ebaluleke kakhulu ukuthi ngenxa yokuthi lo muthi wenziwe ngamaseli akho, uwukwelashwa okwenzelwe wena . Ngakho-ke, lo muthi awukwazi ukwabelwana ngawo nanoma ubani omunye.
Izinto okufanele uzicabangele lapho uphathwa
Isimo sakho sizoqashwa kakhulu odokotela bakho phakathi nalokhu kwelashwa. Kufanele futhi uqaphele lezi zinto.
- Ukozela nokushayela: Ungase uzizwe ulele futhi unesiyezi . Ngakho-ke , ungenzi noma yini edinga ukuphaphama kwengqondo, njengokushayela noma ukusebenzisa imishini esindayo, uze wazi kahle ukuthi lo muthi uthinta kanjani wena.
- Ingozi yokutheleleka: Lokhu kwelashwa kunganciphisa okwesikhashana ikhono lomzimba wakho lokulwa nokugula. Ngakho-ke zama ukuhlala kude nabantu abagulayo. Uma uba nezimpawu ezifana nomkhuhlane, izinhlungu zomzimba, noma umphimbo obuhlungu , shayela udokotela wakho ngokushesha esikhundleni sokuzelapha.
- Ukunikela ngegazi noma ngezitho zomzimba: Gwema ukunikela ngegazi, izitho zomzimba, izicubu, isidoda, noma amaqanda (ama-oocyte) ngenkathi uthatha lolu hlobo lokwelashwa kanye nesikhathi esithile ngemva kwalokho.
- Ukukhulelwa (Kubaluleke Kakhulu): Ungakhulelwa nganoma yisiphi isizathu ngenkathi uthatha lo muthi. Futhi, uma uhlela ukuba nomntwana noma usola ukuthi ukhulelwe, kufanele utshele udokotela wakho ngokushesha. Lo muthi ungalimaza kakhulu ingane engakazalwa.
- Eminye imithi: Tshela udokotela wakho nganoma yimiphi eminye imithi oyithathayo (kufaka phakathi amavithamini kanye nemithi yamakhambi). Imithi yokugoma ephilayo ayitholakali ikakhulukazi ngalesi sikhathi.
- Isimo Esiphuthumayo:Lokhu kunikezwa esibhedlela, ngakho ngeke uphuze imithi eminingi kakhulu. Kodwa-ke, uma kuvela isimo esiphuthumayo, yazisa ithimba lezokwelapha ngokushesha. Uma kudingeka, bazokudlulisela e-Emergency Treatment Unit (ETU) . Uma usola ukuthi kukhona ubuthi, ungashayela i-National Poisons Information Centre e-Colombo National Hospital .
Imiphumela emibi engaba khona yalo muthi
Njengayo yonke imithi, lena ingaba nemiphumela emibi. Eminye yale miphumela kufanele ibikwe ngokushesha, kanti eminye ayibi kakhulu. Bheka ithebula elingezansi.
| Ukuhlukaniswa kwemiphumela emibi | |
|---|---|
| Izinto okufanele uzibike kudokotela wakho noma eqenjini lezokwelapha ngokushesha | |
| Ukungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe noma ulimi. |
| Ubunzima bokuphefumula | Ubunzima bokuphefumula. |
| Izinguquko zengqondo | Ukudideka, ubunzima bokukhuluma noma ukuqonda. |
| Izimpawu zokubalwa kwamaseli egazi aphansi | Izimpawu zokutheleleka: umkhuhlane, ukubanda, umphimbo obuhlungu. Izimpawu zokopha: ukuklwebheka, amabala abomvu esikhumbeni, indle emnyama, igazi emchameni. Inani eliphansi lamaseli abomvu egazi: ukukhathala okukhulu, ukuquleka, ukuphaphatheka. |
| Ezinye izimpawu ezinkulu | Uhudo, ukulahlekelwa yibhalansi, ubuhlungu bemisipha noma amalunga, isicanucanu, ukuhlanza, ukuxhuzula, izimpawu zomfutho wegazi ophansi (isiyezi, ukuquleka). |
| Uma kuqhubeka noma kukhathaza, tshela udokotela wakho. | |
| Imiphumela emibi evamile | Ukuqunjelwa, ukulahlekelwa yisifiso sokudla, ikhanda elibuhlungu, ubuhlungu besisu, ukuvuvukala kwemilenze nezinyawo. |
Lolu hlu aluhlanganisi yonke imiphumela emibi engaba khona. Uma uhlangabezana nanoma yini engavamile, khuluma nodokotela wakho ngayo.
Umlayezo Wokuya Nawe Ekhaya
- I-Tisagenlecleucel iyindlela yokwelapha izakhi zofuzo eyenzelwe wena esebenzisa amangqamuzana akho omzimba ukwelapha umdlavuza.
- Lokhu ukwelashwa okukhethekile okunikezwa esibhedlela, okusetshenziselwa izimo ezinzima ze-leukemia kanye ne-lymphoma.
- Kubalulekile ukuthi utshele udokotela wakho yonke imininingwane yakho yezempilo (izifo, ukungezwani komzimba, ukukhulelwa) ngaphambi kokuqala ukwelashwa.
- Ngesikhathi sokwelashwa, qaphela kakhulu izimpawu zokutheleleka (umkhuhlane, ukukhwehlela). Uma kuvela izimpawu ezinjalo, funa iseluleko sikadokotela ngokushesha.
- Njengoba ungase uzizwe ulele, gwema ukushayela nokwenza imisebenzi edinga ukunakekelwa kuze kube yilapho usululame ngokugcwele.
- Gwema ukukhulelwa ngokuphelele ngesikhathi sokwelashwa. Lokhu kubaluleke kakhulu.
- Ungesabi ukukhuluma nethimba lakho lezokwelapha nganoma yikuphi ukukhathazeka noma ukungabaza ongase ube nakho. Bakhona ukukusiza.
💬 Comments (0)
Awekho amazwana athunyelwe okwamanje. Faka amazwana akho lapha okokuqala ngqa.
Engeza amazwana akho