Ingabe ukhathele ukungezwani nokudla okukhulu? Ake sifunde nge-Xolair (Omalizumab)

Ingabe wena noma ingane yakho ninokungezwani komzimba okukhulu nokudla okuningi? Uma kunjalo, cishe uyazi ukuthi kungaba nzima kangakanani. Ukufunda ilebula kukho konke ukudla okuthengayo esitolo, ukubuza ukuthi ukudla kulungiswa kanjani uma uya endaweni yokudlela, nokukhathazeka ngokudla ngephutha ngisho nento encane oyingezwani nayo... Akulula ukuphila nakho konke lokhu. Kodwa namuhla, sikhuluma ngokwelashwa okusha okungasiza ekuphatheni lesi simo.

Esikhathini esidlule, okuwukuphela kwento umuntu onesifo sokungezwani nokudla esibi ayengayenza kwakuwukugwema ukudla ngokuphelele. Kodwa-ke, kungakhathaliseki ukuthi siqaphile kangakanani, sisengakudla ngengozi. Ngo-2024, i-Xolair yaba umuthi wokuqala owavunyelwa ukunciphisa ubukhali balezi zinkinga zokungezwani nokudla okungahleliwe. Nakuba ingalaphi ukungezwani nokudla, ingasiza kakhulu ekunciphiseni ukwesaba nokukhathazeka okuhambisana nakho.

Iyini i-Xolair? Isebenza kanjani ngempela?

Kalula nje, i-allergy yilapho amasosha ethu omzimba esabela ngokweqile entweni engeyona ingozi. Into ebangela lokhu kusabela ibizwa ngokuthi i-allergen.

Ukungezwani nokudla ngezinye izikhathi kungaba yingozi kakhulu. Lolu hlobo lokusabela okukhulu kokungezwani nokudla lubizwa ngokuthi i-anaphylaxis . Lokhu kungaba yingozi empilweni. Nazi ezinye zezimpawu ezingase zivele.

Indlela engcono kakhulu yokuvimbela lesi simo ukugwema ukudla okubangela ukungezwani komzimba. Kodwa kuthiwani uma ukudle ngengozi?

Yilapho umuthi i-Xolair ungena khona. Isithako esisebenzayo ku-Xolair yi- Omalizumab . Sisebenza ngokuvimba into emzimbeni wethu ebizwa ngokuthi i-Immunoglobulin E (IgE) . Lapho i-allergen ingena emzimbeni, umzimba ukhiqiza inani elikhulu lale IgE. Lapho i-Xolair ivimba le IgE, ukusabela okungafuneki kwesistimu yomzimba kuyancishiswa. Lokhu kusho ukuthi noma ungadla ukudla okuncane ngengozi, amathuba okusabela okukhulu njenge-anaphylaxis ayancishiswa.

Zithini izivivinyo ezenziwe kulo muthi?

Ucwaningo lwezokwelapha ukuze luhlole ukuphepha nokusebenza kahle kwe-Xolair luhilele izingane kanye nabantu abadala abaneminyaka engu-1 kuya kwengu-55 ubudala. Bonke babenokungezwani okukhulu namakinati, okusho ukuthi babengenakukwazi ukudla ngisho nengxenye yamakinati. Ngaphezu kwalokho, bonke babenokungezwani nokudla okungenani okubili okunye ukudla.

Ezinye izinto ezibangela ukungezwani komzimba phakathi kwazo kwakuyilezi:

• Ama-cashew - 56%
• Iqanda - 40%
• Ubisi - 35%
• Ama-walnuts - 44%
• Ama-hazelnut - 13%
• Ukolweni - 11%

Kulolu cwaningo, iqembu elilodwa lanikezwa umuthi i-Xolair, kanti elinye lanikwa i-placebo, umuthi owawufana nomuthi kodwa ongenaso isithako esisebenzayo. Ngemva kwezinyanga ezingu-4-5, ama-67% (izingxenye ezimbili kwezintathu) alabo abathatha i-Xolair abazange babe nokusabela okukhulu ekudleni cishe amantongomane amabili nesigamu. Kodwa-ke, ama-7% kuphela alabo abathatha i-placebo athola.

Futhi, abantu abathatha i-Xolair bakwazi ukudla hhayi nje amantongomane, kodwa nokunye ukudla ababenokungezwani nakho, njenge-cashews, ubisi, namaqanda, ngobuningi obukhulu kunangaphambili, ngaphandle kokusabela okubi kakhulu.

Izinto ezibalulekile okufanele uzazi uma usebenzisa i-Xolair

Kunezinto ezimbalwa okufanele uzikhumbule ngaphambi nangesikhathi usebenzisa lo muthi.

• Gcina umuthi ophuthumayo nawe: Uma une-allergy enkulu, udokotela wakho kungenzeka ukuthi ukunike umuthi ophuthumayo, njenge- epinephrine . Ngisho noma uthatha i-Xolair, kubalulekile ukugcina lo muthi nawe ngaso sonke isikhathi.Uma kwenzeka ukusabela okubi kakhulu, kufanele usebenzise umuthi ngokushesha bese uya egumbini lezimo eziphuthumayo esibhedlela (ETU) ngokushesha okukhulu.
• Lokhu akulona ikhambi elisheshayo: I-Xolair akuyona imithi oyiphuzayo uma une-allergy. Yimithi okudingeka uyiphuze njalo.
• Ungayeki eminye imithi: Ungayeki noma wehlise umthamo wanoma yimiphi eminye imithi yokungezwani komzimba oyisebenzisayo njengamanje ngaphandle kokukhuluma nodokotela wakho.

Ungayisebenzisa kanjani i-Xolair? Ingabe ikhona imiphumela emibi?

I-Xolair umuthi owuketshezi ojovwa ngaphansi kwesikhumba njalo emavikini ama-2 noma ama-4. Udokotela wakho uzonquma umthamo ofanele kanye nesimiso sakho ngokusekelwe esisindweni sakho kanye nezinga le-IgE egazini lakho.

• Imithamo embalwa yokuqala: Izikhathi ezimbalwa zokuqala onikwa ngazo lo muthi nakanjani uzokwenziwa esikhungweni sezempilo njengesibhedlela noma emtholampilo. Lokhu kwenzelwa ukuqapha noma yikuphi ukusabela okubi (i-anaphylaxis) emuthini.
• Indlela yokusebenzisa: Lo muthi unikezwa kusetshenziswa idivayisi elula ukuyisebenzisa, egcwaliswe kusengaphambili ebizwa ngokuthi i-autoinjector noma i-syringe evamile. Tshela udokotela wakho uma une-allergy ne-latex, njengoba amanye ama-syringe angase abe ne-latex.
• Imiphumela emibi: Imiphumela emibi evame kakhulu ubuhlungu nomkhuhlane endaweni yokujova. Akuvamile kakhulu ukuthi kube nokusabela okukhulu kokungezwani nomgomo. Yingakho imithamo embalwa yokuqala inikezwa ngaphansi kokuqashwa kwezokwelapha. Uma uhlangabezana nanoma yiziphi izimpawu ezingavamile, khuluma nodokotela wakho ngokushesha.
• Kwenzekani uma uyeka ukuthatha umuthi? Uma uyeka ukusebenzisa i-Xolair, ukungezwani komzimba kwakho kungase kubuyele esimweni sako sangaphambilini.

Lo muthi awufanele wonke umuntu. Kubalulekile ukuxoxa nodokotela wakho noma udokotela wezifo ezibangelwa ukungezwani komzimba/isazi sokugomela ukuthi ukulungele yini wena, ukuthi yiziphi izinzuzo nezingozi, nokuthi ungawuthola kanjani.